Cancer metastasis database

Annotation category 5

Gene information

Gene ID 3586
Symbol

IL10

Synonymous

CSIF|GVHDS|IL-10|IL10A|TGIF

Full name

interleukin 10

Gene description

T-cell growth inhibitory factor|cytokine synthesis inhibitory factor|interleukin-10

Cytoband

1q31-q32

Gene type

protein-coding

Synonymous

MIM:124092; HGNC:HGNC:5962; Ensembl:ENSG00000136634; HPRD:00495; Vega:OTTHUMG00000036386

COSMIC somatic mutation

Mutation (CDS; AA; Chr)

Site

Histology

Mutation Type

c.530G>A; p.R177Q; 1:206768643-206768643

 skinmalignant_melanomaSubstitution - Missense

c.498C>T; p.N166N; 1:206768675-206768675

 central_nervous_system; brainglioma; astrocytoma_Grade_IVSubstitution - coding silent

c.498C>T; p.N166N; 1:206768675-206768675

 central_nervous_system; brainglioma; astrocytoma_Grade_IVSubstitution - coding silent

c.312C>T; p.D104D; 1:206770973-206770973

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - coding silent

c.360G>A; p.R120R; 1:206770925-206770925

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.255G>A; p.E85E; 1:206771030-206771030

 large_intestinecarcinoma; adenocarcinomaSubstitution - coding silent

c.320C>T; p.A107V; 1:206770965-206770965

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.342G>T; p.E114D; 1:206770943-206770943

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - Missense

c.373C>T; p.R125C; 1:206770912-206770912

 prostatecarcinomaSubstitution - Missense

c.373C>T; p.R125C; 1:206770912-206770912

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.373C>T; p.R125C; 1:206770912-206770912

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.73C>T; p.Q25*; 1:206772363-206772363

 ovarycarcinoma; serous_carcinomaSubstitution - Nonsense

c.188A>G; p.N63S; 1:206771393-206771393

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.239G>A; p.C80Y; 1:206771046-206771046

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.376T>C; p.C126R; 1:206770909-206770909

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.72C>A; p.T24T; 1:206772364-206772364

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.382C>G; p.R128G; 1:206769891-206769891

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.297G>A; p.E99E; 1:206770988-206770988

 urinary_tract; bladdercarcinomaSubstitution - coding silent

c.258G>A; p.M86I; 1:206771027-206771027

 skinmalignant_melanomaSubstitution - Missense

c.414C>T; p.A138A; 1:206769859-206769859

 bone; femurEwings_sarcoma-peripheral_primitive_neuroectodermal_tumourSubstitution - coding silent

c.27C>T; p.C9C; 1:206772409-206772409

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.166C>T; p.Q56*; 1:206771415-206771415

 lungcarcinoma; adenocarcinomaSubstitution - Nonsense

c.327G>T; p.V109V; 1:206770958-206770958

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.388C>A; p.L130I; 1:206769885-206769885

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - Missense

c.379-1G>A; p.?; 1:206769895-206769895

 stomachcarcinoma; adenocarcinomaUnknown

c.445-3_475del34; p.?; 1:206768698-206768731

 ovarycarcinoma; serous_carcinomaUnknown

c.285G>A; p.M95I; 1:206771000-206771000

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.382C>T; p.R128*; 1:206769891-206769891

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Nonsense

c.248_272del25; p.L83fs*4; 1:206771013-206771037

 stomachcarcinoma; intestinal_adenocarcinomaDeletion - Frameshift

c.2T>C; p.M1T; 1:206772434-206772434

 oesophaguscarcinomaSubstitution - Missense

c.179A>G; p.Q60R; 1:206771402-206771402

 stomachcarcinoma; intestinal_adenocarcinomaSubstitution - Missense

c.337G>C; p.G113R; 1:206770948-206770948

 lungcarcinoma; small_cell_carcinomaSubstitution - Missense

c.321G>A; p.A107A; 1:206770964-206770964

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - coding silent

c.321G>A; p.A107A; 1:206770964-206770964

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.415G>A; p.V139M; 1:206769858-206769858

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.415G>A; p.V139M; 1:206769858-206769858

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.500A>G; p.Y167C; 1:206768673-206768673

 ovaryother; neoplasmSubstitution - Missense

c.444G>A; p.K148K; 1:206769829-206769829

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent