| Gene ID | 3570 |
| Symbol | IL6R |
| Synonymous | CD126|IL-6R-1|IL-6RA|IL6Q|IL6RA|IL6RQ|gp80 |
| Full name | interleukin 6 receptor |
| Gene description | CD126 antigen|IL-6 receptor subunit alpha|IL-6R 1|interleukin-6 receptor subunit alpha|membrane glycoprotein 80 |
| Cytoband | 1q21 |
| Gene type | protein-coding |
| Synonymous | MIM:147880; HGNC:HGNC:6019; Ensembl:ENSG00000160712; HPRD:01000; Vega:OTTHUMG00000036073 |
Mutation (CDS; AA; Chr) | Site | Histology | Mutation Type |
|---|---|---|---|
c.580G>A; p.V194I; 1:154434640-154434640 |
ovary | carcinoma; serous_carcinoma | Substitution - Missense |
c.1329G>A; p.S443S; 1:154465302-154465302 |
ovary | carcinoma; serous_carcinoma | Substitution - coding silent |
c.841G>A; p.D281N; 1:154436002-154436002 |
large_intestine; caecum | carcinoma; adenocarcinoma | Substitution - Missense |
c.448G>T; p.V150L; 1:154430596-154430596 |
breast | carcinoma | Substitution - Missense |
c.836_838>A; p.I279fs*45; 1:154435997-154435999 |
breast | carcinoma; ductal_carcinoma | Complex - frameshift |
c.981G>T; p.V327V; 1:154448156-154448156 |
ovary | carcinoma; serous_carcinoma | Substitution - coding silent |