Cancer metastasis database

Annotation category 5

Gene information

Gene ID 3552
Symbol

IL1A

Synonymous

IL-1A|IL1|IL1-ALPHA|IL1F1

Full name

interleukin 1, alpha

Gene description

IL-1 alpha|hematopoietin-1|interleukin-1 alpha|preinterleukin 1 alpha|pro-interleukin-1-alpha

Cytoband

2q14

Gene type

protein-coding

Synonymous

MIM:147760; HGNC:HGNC:5991; HPRD:00988

COSMIC somatic mutation

Mutation (CDS; AA; Chr)

Site

Histology

Mutation Type

c.234G>A; p.G78G; 2:112781689-112781689

 skinmalignant_melanomaSubstitution - coding silent

c.234G>A; p.G78G; 2:112781689-112781689

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.300C>T; p.I100I; 2:112781623-112781623

 oesophaguscarcinoma; adenocarcinomaSubstitution - coding silent

c.652G>A; p.E218K; 2:112775231-112775231

 breastcarcinomaSubstitution - Missense

c.381G>A; p.M127I; 2:112779605-112779605

 central_nervous_system; brainglioma; astrocytoma_Grade_IVSubstitution - Missense

c.432A>G; p.I144M; 2:112779554-112779554

 livercarcinomaSubstitution - Missense

c.461C>T; p.A154V; 2:112779525-112779525

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.184A>T; p.T62S; 2:112781739-112781739

 lungcarcinoma; small_cell_carcinomaSubstitution - Missense

c.184A>T; p.T62S; 2:112781739-112781739

 lungcarcinoma; small_cell_carcinomaSubstitution - Missense

c.659A>G; p.N220S; 2:112775224-112775224

 skinmalignant_melanomaSubstitution - Missense

c.121G>A; p.G41S; 2:112781802-112781802

 skinmalignant_melanomaSubstitution - Missense

c.72C>A; p.S24S; 2:112782740-112782740

 kidneycarcinoma; papillary_renal_cell_carcinomaSubstitution - coding silent

c.232G>C; p.G78R; 2:112781691-112781691

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.793C>T; p.Q265*; 2:112775090-112775090

 urinary_tract; bladdercarcinomaSubstitution - Nonsense

c.676delG; p.E226fs*>46; 2:112775207-112775207

 skin; head_neckcarcinoma; squamous_cell_carcinomaDeletion - Frameshift

c.320A>G; p.E107G; 2:112779666-112779666

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.715C>A; p.H239N; 2:112775168-112775168

 lung; right_upper_lobecarcinoma; adenocarcinomaSubstitution - Missense

c.215T>G; p.V72G; 2:112781708-112781708

 breastcarcinomaSubstitution - Missense

c.340G>T; p.A114S; 2:112779646-112779646

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.340G>T; p.A114S; 2:112779646-112779646

 haematopoietic_and_lymphoid_tissuehaematopoietic_neoplasm; acute_myeloid_leukaemiaSubstitution - Missense

c.685G>A; p.G229S; 2:112775198-112775198

 breastcarcinomaSubstitution - Missense

c.76G>A; p.D26N; 2:112782736-112782736

 skinmalignant_melanomaSubstitution - Missense

c.544G>A; p.V182M; 2:112778058-112778058

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.804A>C; p.E268D; 2:112775079-112775079

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.258G>C; p.L86F; 2:112781665-112781665

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.97-1G>T; p.?; 2:112781827-112781827

 livercarcinomaUnknown

c.253C>T; p.R85W; 2:112781670-112781670

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.397G>T; p.E133*; 2:112779589-112779589

 prostatecarcinoma; adenocarcinomaSubstitution - Nonsense

c.110A>G; p.H37R; 2:112781813-112781813

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.568C>T; p.Q190*; 2:112778034-112778034

 skinmalignant_melanomaSubstitution - Nonsense

c.79C>A; p.H27N; 2:112782733-112782733

 autonomic_ganglianeuroblastomaSubstitution - Missense

c.554G>A; p.R185K; 2:112778048-112778048

 skinmalignant_melanomaSubstitution - Missense

c.813G>A; p.A271A; 2:112775070-112775070

 central_nervous_system; brainglioma; astrocytoma_Grade_IVSubstitution - coding silent

c.36G>A; p.K12K; 2:112783735-112783735

 skinmalignant_melanomaSubstitution - coding silent

c.125C>A; p.P42Q; 2:112781798-112781798

 kidneyother; neoplasmSubstitution - Missense

c.623C>G; p.P208R; 2:112775260-112775260

 lung; right_upper_lobecarcinoma; adenocarcinomaSubstitution - Missense

c.623C>G; p.P208R; 2:112775260-112775260

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.49G>A; p.E17K; 2:112782763-112782763

 skinmalignant_melanomaSubstitution - Missense

c.586C>T; p.Q196*; 2:112778016-112778016

 urinary_tract; bladdercarcinoma; transitional_cell_carcinomaSubstitution - Nonsense

c.586C>T; p.Q196*; 2:112778016-112778016

 urinary_tract; bladdercarcinomaSubstitution - Nonsense

c.397G>A; p.E133K; 2:112779589-112779589

 skinmalignant_melanomaSubstitution - Missense

c.768G>A; p.G256G; 2:112775115-112775115

 skinmalignant_melanomaSubstitution - coding silent

c.319+2T>C; p.?; 2:112781602-112781602

 large_intestine; coloncarcinoma; adenocarcinomaUnknown

c.168C>G; p.I56M; 2:112781755-112781755

 upper_aerodigestive_tract; mouthcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.168C>G; p.I56M; 2:112781755-112781755

 upper_aerodigestive_tract; mouthcarcinomaSubstitution - Missense

c.505G>T; p.G169C; 2:112778097-112778097

 large_intestine; colonNSSubstitution - Missense

c.321A>G; p.E107E; 2:112779665-112779665

 lungcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.622C>T; p.P208S; 2:112775261-112775261

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.324C>T; p.I108I; 2:112779662-112779662

 skinmalignant_melanomaSubstitution - coding silent

c.129C>A; p.L43L; 2:112781794-112781794

 boneEwings_sarcoma-peripheral_primitive_neuroectodermal_tumourSubstitution - coding silent

c.301G>A; p.A101T; 2:112781622-112781622

 stomachcarcinoma; adenocarcinomaSubstitution - Missense