Cancer metastasis database

Annotation category 5

Gene information

Gene ID 3399
Symbol

ID3

Synonymous

HEIR-1|bHLHb25

Full name

inhibitor of DNA binding 3, dominant negative helix-loop-helix protein

Gene description

DNA-binding protein inhibitor ID-3|ID-like protein inhibitor HLH 1R21|class B basic helix-loop-helix protein 25|helix-loop-helix protein HEIR-1|inhibitor of differentiation 3

Cytoband

1p36.13-p36.12

Gene type

protein-coding

Synonymous

MIM:600277; HGNC:HGNC:5362; Ensembl:ENSG00000117318; HPRD:02608; Vega:OTTHUMG00000003229

COSMIC somatic mutation

Mutation (CDS; AA; Chr)

Site

Histology

Mutation Type

c.173T>A; p.V58D; 1:23559254-23559254

 haematopoietic_and_lymphoid_tissue; lymph_nodelymphoid_neoplasm; follicular_lymphomaSubstitution - Missense

c.173T>A; p.V58D; 1:23559254-23559254

 haematopoietic_and_lymphoid_tissue; soft_tissuelymphoid_neoplasm; diffuse_large_B_cell_lymphomaSubstitution - Missense

c.127_129delGAC; p.D43delD; 1:23559298-23559300

 stomachcarcinoma; intestinal_adenocarcinomaDeletion - In frame

c.121C>T; p.L41L; 1:23559306-23559306

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.155G>T; p.R52L; 1:23559272-23559272

 lung; right_upper_lobecarcinoma; adenocarcinomaSubstitution - Missense

c.17C>T; p.P6L; 1:23559410-23559410

 lungcarcinoma; small_cell_carcinomaSubstitution - Missense

c.17C>T; p.P6L; 1:23559410-23559410

 livercarcinomaSubstitution - Missense

c.17C>T; p.P6L; 1:23559410-23559410

 livercarcinomaSubstitution - Missense

c.120G>TG; p.L40fs*26; 1:23559307-23559307

 haematopoietic_and_lymphoid_tissuelymphoid_neoplasm; Burkitt_lymphomaComplex - frameshift

c.301-1G>A; p.?; 1:23559020-23559020

 haematopoietic_and_lymphoid_tissuelymphoid_neoplasm; Burkitt_lymphomaUnknown

c.227A>G; p.Y76C; 1:23559200-23559200

 haematopoietic_and_lymphoid_tissuelymphoid_neoplasm; Burkitt_lymphomaSubstitution - Missense

c.241C>T; p.Q81*; 1:23559186-23559186

 haematopoietic_and_lymphoid_tissuelymphoid_neoplasm; Burkitt_lymphomaSubstitution - Nonsense

c.277G>A; p.D93N; 1:23559150-23559150

 haematopoietic_and_lymphoid_tissuelymphoid_neoplasm; Burkitt_lymphomaSubstitution - Missense

c.241C>T; p.Q81*; 1:23559186-23559186

 haematopoietic_and_lymphoid_tissuelymphoid_neoplasm; Burkitt_lymphomaSubstitution - Nonsense

c.228_229insTAC; p.Y76_I77insY; 1:23559198-23559199

 haematopoietic_and_lymphoid_tissuelymphoid_neoplasm; Burkitt_lymphomaInsertion - In frame

c.250C>G; p.L84V; 1:23559177-23559177

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.65T>C; p.L22P; 1:23559362-23559362

 livercarcinoma; hepatocellular_carcinomaSubstitution - Missense

c.206delT; p.I69fs*14; 1:23559221-23559221

 haematopoietic_and_lymphoid_tissuelymphoid_neoplasm; Burkitt_lymphomaDeletion - Frameshift

c.200T>G; p.V67G; 1:23559227-23559227

 breastcarcinomaSubstitution - Missense

c.249C>T; p.V83V; 1:23559178-23559178

 large_intestinecarcinoma; adenocarcinomaSubstitution - coding silent

c.154C>T; p.R52W; 1:23559273-23559273

 haematopoietic_and_lymphoid_tissuelymphoid_neoplasm; Burkitt_lymphomaSubstitution - Missense

c.157G>A; p.E53K; 1:23559270-23559270

 haematopoietic_and_lymphoid_tissuelymphoid_neoplasm; Burkitt_lymphomaSubstitution - Missense

c.166C>T; p.P56S; 1:23559261-23559261

 haematopoietic_and_lymphoid_tissuelymphoid_neoplasm; Burkitt_lymphomaSubstitution - Missense

c.166C>T; p.P56S; 1:23559261-23559261

 haematopoietic_and_lymphoid_tissuelymphoid_neoplasm; Burkitt_lymphomaSubstitution - Missense

c.166C>T; p.P56S; 1:23559261-23559261

 haematopoietic_and_lymphoid_tissuelymphoid_neoplasm; Burkitt_lymphomaSubstitution - Missense

c.166C>T; p.P56S; 1:23559261-23559261

 haematopoietic_and_lymphoid_tissuelymphoid_neoplasm; Burkitt_lymphomaSubstitution - Missense

c.204A>T; p.E68D; 1:23559223-23559223

 haematopoietic_and_lymphoid_tissuelymphoid_neoplasm; Burkitt_lymphomaSubstitution - Missense

c.167C>T; p.P56L; 1:23559260-23559260

 haematopoietic_and_lymphoid_tissuelymphoid_neoplasm; Burkitt_lymphomaSubstitution - Missense

c.167C>T; p.P56L; 1:23559260-23559260

 haematopoietic_and_lymphoid_tissuelymphoid_neoplasm; Burkitt_lymphomaSubstitution - Missense

c.283C>T; p.P95S; 1:23559144-23559144

 central_nervous_system; brainglioma; astrocytoma_Grade_IVSubstitution - Missense

c.300G>A; p.Q100Q; 1:23559127-23559127

 haematopoietic_and_lymphoid_tissuelymphoid_neoplasmSubstitution - coding silent

c.188A>G; p.Q63R; 1:23559239-23559239

 stomachcarcinoma; intestinal_adenocarcinomaSubstitution - Missense

c.187C>T; p.Q63*; 1:23559240-23559240

 haematopoietic_and_lymphoid_tissuelymphoid_neoplasm; Burkitt_lymphomaSubstitution - Nonsense

c.144C>G; p.Y48*; 1:23559283-23559283

 haematopoietic_and_lymphoid_tissuelymphoid_neoplasm; Burkitt_lymphomaSubstitution - Nonsense

c.235G>T; p.D79Y; 1:23559192-23559192

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.208C>G; p.L70V; 1:23559219-23559219

 haematopoietic_and_lymphoid_tissuelymphoid_neoplasmSubstitution - Missense

c.156G>A; p.R52R; 1:23559271-23559271

 lungcarcinoma; adenocarcinomaSubstitution - coding silent

c.130A>G; p.M44V; 1:23559297-23559297

 haematopoietic_and_lymphoid_tissuelymphoid_neoplasm; Burkitt_lymphomaSubstitution - Missense

c.284C>A; p.P95H; 1:23559143-23559143

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.190C>T; p.L64F; 1:23559237-23559237

 haematopoietic_and_lymphoid_tissuelymphoid_neoplasm; Burkitt_lymphomaSubstitution - Missense

c.190C>T; p.L64F; 1:23559237-23559237

 haematopoietic_and_lymphoid_tissuelymphoid_neoplasmSubstitution - Missense

c.190C>T; p.L64F; 1:23559237-23559237

 haematopoietic_and_lymphoid_tissuelymphoid_neoplasmSubstitution - Missense

c.143_145delACT; p.Y48delY; 1:23559282-23559284

 haematopoietic_and_lymphoid_tissuelymphoid_neoplasm; Burkitt_lymphomaDeletion - In frame

c.300+2T>C; p.?; 1:23559125-23559125

 haematopoietic_and_lymphoid_tissuelymphoid_neoplasm; Burkitt_lymphomaUnknown