Cancer metastasis database

Annotation category 5

Gene information

Gene ID 3383
Symbol

ICAM1

Synonymous

BB2|CD54|P3.58

Full name

intercellular adhesion molecule 1

Gene description

ICAM-1|cell surface glycoprotein P3.58|intercellular adhesion molecule 1 (CD54), human rhinovirus receptor|major group rhinovirus receptor

Cytoband

19p13.3-p13.2

Gene type

protein-coding

Synonymous

MIM:147840; HGNC:HGNC:5344; Ensembl:ENSG00000090339; HPRD:00996; Vega:OTTHUMG00000180403

COSMIC somatic mutation

Mutation (CDS; AA; Chr)

Site

Histology

Mutation Type

c.1503C>T; p.Y501Y; 19:10285191-10285191

 lungcarcinoma; adenocarcinomaSubstitution - coding silent

c.1534T>C; p.Y512H; 19:10285222-10285222

 upper_aerodigestive_tract; mouthcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.811T>C; p.S271P; 19:10284206-10284206

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.1022C>T; p.T341M; 19:10284499-10284499

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.1022C>T; p.T341M; 19:10284499-10284499

 central_nervous_system; brainglioma; astrocytoma_Grade_IVSubstitution - Missense

c.1359C>G; p.G453G; 19:10284961-10284961

 lungcarcinoma; adenocarcinomaSubstitution - coding silent

c.747G>A; p.Q249Q; 19:10284142-10284142

 prostatecarcinoma; adenocarcinomaSubstitution - coding silent

c.1287C>G; p.L429L; 19:10284889-10284889

 urinary_tract; bladdercarcinomaSubstitution - coding silent

c.941A>G; p.N314S; 19:10284418-10284418

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.761T>A; p.L254Q; 19:10284156-10284156

 autonomic_ganglianeuroblastomaSubstitution - Missense

c.279T>G; p.Y93*; 19:10274976-10274976

 skin; trunkmalignant_melanomaSubstitution - Nonsense

c.932C>T; p.P311L; 19:10284409-10284409

 ovarycarcinoma; serous_carcinomaSubstitution - Missense

c.453C>T; p.L151L; 19:10283602-10283602

 skinmalignant_melanomaSubstitution - coding silent

c.96C>T; p.S32S; 19:10274793-10274793

 skinmalignant_melanomaSubstitution - coding silent

c.936G>A; p.A312A; 19:10284413-10284413

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - coding silent

c.494A>G; p.E165G; 19:10283643-10283643

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.1416G>C; p.V472V; 19:10285018-10285018

 lungcarcinoma; adenocarcinomaSubstitution - coding silent

c.1243C>T; p.Q415*; 19:10284845-10284845

 stomachcarcinoma; adenocarcinomaSubstitution - Nonsense

c.1324delG; p.E443fs*3; 19:10284926-10284926

 large_intestine; coloncarcinoma; adenocarcinomaDeletion - Frameshift

c.1249C>G; p.P417A; 19:10284851-10284851

 urinary_tract; bladdercarcinomaSubstitution - Missense

c.1063C>T; p.Q355*; 19:10284540-10284540

 skinmalignant_melanomaSubstitution - Nonsense

c.802G>A; p.D268N; 19:10284197-10284197

 central_nervous_system; braingliomaSubstitution - Missense

c.771G>C; p.Q257H; 19:10284166-10284166

 urinary_tract; bladdercarcinomaSubstitution - Missense

c.581C>T; p.P194L; 19:10283730-10283730

 skinmalignant_melanomaSubstitution - Missense

c.516G>A; p.T172T; 19:10283665-10283665

 pancreascarcinoma; ductal_carcinomaSubstitution - coding silent

c.366C>T; p.P122P; 19:10283515-10283515

 central_nervous_system; brainglioma; astrocytoma_Grade_IVSubstitution - coding silent

c.1403G>A; p.R468H; 19:10285005-10285005

 pancreascarcinoma; acinar_carcinomaSubstitution - Missense

c.1468G>A; p.A490T; 19:10285156-10285156

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.1468G>A; p.A490T; 19:10285156-10285156

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.10A>C; p.S4R; 19:10271169-10271169

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.733G>T; p.V245F; 19:10284128-10284128

 haematopoietic_and_lymphoid_tissuelymphoid_neoplasm; acute_lymphoblastic_leukaemiaSubstitution - Missense

c.226C>T; p.R76W; 19:10274923-10274923

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.1056G>C; p.P352P; 19:10284533-10284533

 urinary_tract; bladdercarcinomaSubstitution - coding silent

c.1056G>C; p.P352P; 19:10284533-10284533

 urinary_tract; bladdercarcinoma; transitional_cell_carcinomaSubstitution - coding silent

c.272T>C; p.M91T; 19:10274969-10274969

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.292G>C; p.D98H; 19:10274989-10274989

 urinary_tract; bladdercarcinomaSubstitution - Missense

c.1519C>T; p.R507W; 19:10285207-10285207

 haematopoietic_and_lymphoid_tissuelymphoid_neoplasm; mantle_cell_lymphomaSubstitution - Missense

c.1185C>T; p.G395G; 19:10284787-10284787

 large_intestinecarcinoma; adenocarcinomaSubstitution - coding silent

c.1147C>A; p.H383N; 19:10284624-10284624

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.1351C>T; p.L451F; 19:10284953-10284953

 skin; facecarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.1171C>T; p.R391C; 19:10284648-10284648

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.1090G>A; p.D364N; 19:10284567-10284567

 oesophaguscarcinoma; adenocarcinomaSubstitution - Missense

c.236A>G; p.Y79C; 19:10274933-10274933

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.354G>A; p.L118L; 19:10283503-10283503

 stomachcarcinoma; adenocarcinomaSubstitution - coding silent

c.51C>T; p.L17L; 19:10271210-10271210

 thyroidcarcinomaSubstitution - coding silent

c.720C>T; p.D240D; 19:10284115-10284115

 stomachcarcinoma; adenocarcinomaSubstitution - coding silent

c.720C>T; p.D240D; 19:10284115-10284115

 central_nervous_system; brainglioma; astrocytoma_Grade_IVSubstitution - coding silent

c.720C>T; p.D240D; 19:10284115-10284115

 central_nervous_system; brainglioma; astrocytoma_Grade_IVSubstitution - coding silent

c.860G>A; p.R287Q; 19:10284255-10284255

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.306A>G; p.T102T; 19:10275003-10275003

 stomachcarcinoma; adenocarcinomaSubstitution - coding silent

c.1392G>A; p.G464G; 19:10284994-10284994

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.969A>G; p.S323S; 19:10284446-10284446

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.663T>C; p.L221L; 19:10284058-10284058

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - coding silent

c.979G>A; p.E327K; 19:10284456-10284456

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.1589C>T; p.T530M; 19:10285277-10285277

 upper_aerodigestive_tract; mouthcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.1589C>T; p.T530M; 19:10285277-10285277

 upper_aerodigestive_tract; mouthcarcinomaSubstitution - Missense

c.1404C>T; p.R468R; 19:10285006-10285006

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.428G>T; p.R143L; 19:10283577-10283577

 prostatecarcinoma; adenocarcinomaSubstitution - Missense

c.601G>C; p.E201Q; 19:10283750-10283750

 breastcarcinomaSubstitution - Missense

c.706G>T; p.V236F; 19:10284101-10284101

 livercarcinomaSubstitution - Missense

c.706G>T; p.V236F; 19:10284101-10284101

 livercarcinomaSubstitution - Missense

c.1494C>T; p.L498L; 19:10285182-10285182

 lung; right_upper_lobecarcinoma; adenocarcinomaSubstitution - coding silent

c.1267G>A; p.G423R; 19:10284869-10284869

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.674G>A; p.R225Q; 19:10284069-10284069

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.652C>T; p.P218S; 19:10284047-10284047

 breastcarcinomaSubstitution - Missense

c.867G>A; p.T289T; 19:10284262-10284262

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.1446C>T; p.V482V; 19:10285134-10285134

 thyroidcarcinomaSubstitution - coding silent

c.1211C>T; p.P404L; 19:10284813-10284813

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.571G>C; p.D191H; 19:10283720-10283720

 haematopoietic_and_lymphoid_tissuelymphoid_neoplasm; plasma_cell_myelomaSubstitution - Missense

c.1475T>A; p.I492K; 19:10285163-10285163

 kidneycarcinoma; papillary_renal_cell_carcinomaSubstitution - Missense