Cancer metastasis database

Annotation category 5

Gene information

Gene ID 335
Symbol

APOA1

Synonymous

-

Full name

apolipoprotein A-I

Gene description

apo-AI

Cytoband

11q23-q24

Gene type

protein-coding

Synonymous

MIM:107680; HGNC:HGNC:600; Ensembl:ENSG00000118137; HPRD:02517; Vega:OTTHUMG00000046112

COSMIC somatic mutation

Mutation (CDS; AA; Chr)

Site

Histology

Mutation Type

c.772G>C; p.E258Q; 11:116835840-116835840

 lung; right_upper_lobecarcinoma; adenocarcinomaSubstitution - Missense

c.779A>G; p.Y260C; 11:116835833-116835833

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.11C>T; p.A4V; 11:116837377-116837377

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.577G>A; p.E193K; 11:116836035-116836035

 oesophaguscarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.278A>G; p.Q93R; 11:116836334-116836334

 skinmalignant_melanomaSubstitution - Missense

c.687G>A; p.E229E; 11:116835925-116835925

 breastcarcinomaSubstitution - coding silent

c.254G>A; p.R85H; 11:116836358-116836358

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.254G>A; p.R85H; 11:116836358-116836358

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.529C>T; p.R177C; 11:116836083-116836083

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.92C>T; p.P31L; 11:116837109-116837109

 skin; extremitymalignant_melanomaSubstitution - Missense

c.43G>T; p.G15W; 11:116837345-116837345

 livercarcinoma; hepatocellular_carcinomaSubstitution - Missense

c.433C>G; p.P145A; 11:116836179-116836179

 lungcarcinoma; small_cell_carcinomaSubstitution - Missense

c.115G>A; p.A39T; 11:116837086-116837086

 prostatecarcinomaSubstitution - Missense

c.211C>A; p.L71I; 11:116836401-116836401

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.44G>A; p.G15E; 11:116837157-116837157

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.280G>A; p.E94K; 11:116836332-116836332

 central_nervous_system; braingliomaSubstitution - Missense

c.699C>A; p.P233P; 11:116835913-116835913

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - coding silent

c.41C>T; p.T14M; 11:116837347-116837347

 lungcarcinoma; small_cell_carcinomaSubstitution - Missense

c.41C>T; p.T14M; 11:116837347-116837347

 large_intestine; coloncarcinomaSubstitution - Missense

c.41C>T; p.T14M; 11:116837347-116837347

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.146G>A; p.S49N; 11:116837055-116837055

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.85delC; p.Q29fs*7; 11:116837116-116837116

 large_intestine; coloncarcinoma; adenocarcinomaDeletion - Frameshift

c.85delC; p.Q29fs*7; 11:116837116-116837116

 large_intestine; caecumcarcinoma; adenocarcinomaDeletion - Frameshift

c.55C>T; p.R19W; 11:116837146-116837146

 stomachcarcinoma; intestinal_adenocarcinomaSubstitution - Missense

c.85delC; p.Q29fs*7; 11:116837116-116837116

 large_intestine; coloncarcinoma; adenocarcinomaDeletion - Frameshift

c.256G>A; p.E86K; 11:116836356-116836356

 oesophagus; lower_thirdcarcinoma; adenocarcinomaSubstitution - Missense

c.179C>T; p.S60F; 11:116837022-116837022

 skin; extremitymalignant_melanomaSubstitution - Missense

c.156C>T; p.D52D; 11:116837045-116837045

 skinmalignant_melanomaSubstitution - coding silent

c.750G>T; p.K250N; 11:116835862-116835862

 kidneyother; neoplasmSubstitution - Missense

c.230T>C; p.V77A; 11:116836382-116836382

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.28G>A; p.V10M; 11:116837360-116837360

 breastcarcinomaSubstitution - Missense

c.28G>A; p.V10M; 11:116837360-116837360

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.190A>G; p.K64E; 11:116837011-116837011

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.503T>G; p.L168R; 11:116836109-116836109

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.330G>C; p.M110I; 11:116836282-116836282

 breastcarcinomaSubstitution - Missense

c.85_86insC; p.Q29fs*30; 11:116837115-116837116

 large_intestine; coloncarcinoma; adenocarcinomaInsertion - Frameshift

c.528G>A; p.A176A; 11:116836084-116836084

 stomachcarcinoma; adenocarcinomaSubstitution - coding silent

c.315C>A; p.G105G; 11:116836297-116836297

 upper_aerodigestive_tract; mouthcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.315C>A; p.G105G; 11:116836297-116836297

 upper_aerodigestive_tract; mouthcarcinomaSubstitution - coding silent

c.504_505GG>AA; p.G169S; 11:116836107-116836108

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.313G>T; p.G105C; 11:116836299-116836299

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.648C>T; p.Y216Y; 11:116835964-116835964

 large_intestinecarcinoma; adenocarcinomaSubstitution - coding silent

c.100C>T; p.R34*; 11:116837101-116837101

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Nonsense

c.401A>C; p.E134A; 11:116836211-116836211

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.766G>T; p.A256S; 11:116835846-116835846

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.101G>A; p.R34Q; 11:116837100-116837100

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.315C>T; p.G105G; 11:116836297-116836297

 stomachcarcinoma; adenocarcinomaSubstitution - coding silent

c.44G>T; p.G15V; 11:116837157-116837157

 skinmalignant_melanomaSubstitution - Missense

c.518G>A; p.R173H; 11:116836094-116836094

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.76G>A; p.E26K; 11:116837125-116837125

 lung; right_upper_lobecarcinoma; adenocarcinomaSubstitution - Missense