lung cancer gene and literature database Home

Annotation category 5

Basic annotation
Ontology and pathways
Literature evidence
Curated literatures
Expression
Gene expression chart
Somatic mutation
COSMIC and TCGA mutations
Network
Gene interaction
ceRNA
Gene-related ceRNA

Gene information

Gene ID	3304
Symbol	HSPA1B
Synonymous	HSP70-1B\|HSP70-2
Full name	heat shock 70kDa protein 1B
Gene description	HSP70-1/HSP70-2\|HSP70.1/HSP70.2\|heat shock 70 kDa protein 1/2\|heat shock 70 kDa protein 1A/1B\|heat shock 70kD protein 1B
Cytoband	6p21.3
Gene type	protein-coding
Synonymous	MIM:603012; HGNC:HGNC:5233; Ensembl:ENSG00000204388; HPRD:06784; Vega:OTTHUMG00000031202

COSMIC somatic mutation

Mutation (CDS; AA; Chr)	Site	Histology	Mutation Type
c.5C>T; p.A2V; 6:31827955-31827955	breast	carcinoma	Substitution - Missense
c.1860C>G; p.G620G; 6:31829810-31829810	liver	carcinoma; hepatocellular_carcinoma	Substitution - coding silent
c.1860C>G; p.G620G; 6:31829810-31829810	thyroid	other; neoplasm	Substitution - coding silent
c.1545C>A; p.I515I; 6:31829495-31829495	thyroid	other; neoplasm	Substitution - coding silent
c.1907C>A; p.T636N; 6:31829857-31829857	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.1758G>T; p.L586F; 6:31829708-31829708	biliary_tract; bile_duct	carcinoma; adenocarcinoma	Substitution - Missense
c.80A>G; p.E27G; 6:31828030-31828030	urinary_tract; bladder	carcinoma	Substitution - Missense
c.222T>C; p.I74I; 6:31828172-31828172	thyroid	other; neoplasm	Substitution - coding silent
c.222T>C; p.I74I; 6:31828172-31828172	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.222T>C; p.I74I; 6:31828172-31828172	thyroid	other; neoplasm	Substitution - coding silent
c.1242C>G; p.I414M; 6:31829192-31829192	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1736C>A; p.S579*; 6:31829686-31829686	breast	carcinoma; ductal_carcinoma	Substitution - Nonsense
c.1753A>C; p.T585P; 6:31829703-31829703	biliary_tract; bile_duct	carcinoma; adenocarcinoma	Substitution - Missense
c.112_113insC; p.S40fs*30; 6:31828062-31828063	large_intestine; colon	carcinoma; adenocarcinoma	Insertion - Frameshift
c.1761C>G; p.A587A; 6:31829711-31829711	prostate	carcinoma; adenocarcinoma	Substitution - coding silent
c.1710T>G; p.V570V; 6:31829660-31829660	thyroid	other; neoplasm	Substitution - coding silent
c.330G>C; p.E110D; 6:31828280-31828280	thyroid	other; neoplasm	Substitution - Missense
c.330G>C; p.E110D; 6:31828280-31828280	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.330G>C; p.E110D; 6:31828280-31828280	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense