Cancer metastasis database

Annotation category 5

Gene information

Gene ID 3291
Symbol

HSD11B2

Synonymous

AME|AME1|HSD11K|HSD2|SDR9C3

Full name

hydroxysteroid (11-beta) dehydrogenase 2

Gene description

-HSD11 type II|11-DH2|11-beta-HSD2|11-beta-hydroxysteroid dehydrogenase type 2|11-beta-hydroxysteroid dehydrogenase type II|NAD-dependent 11-beta-hydroxysteroid dehydrogenase|corticosteroid 11-beta-dehydrogenase isozyme 2|short chain dehydrogenase/reducta

Cytoband

16q22

Gene type

protein-coding

Synonymous

MIM:614232; HGNC:HGNC:5209; Ensembl:ENSG00000176387; HPRD:01958; Vega:OTTHUMG00000137507

COSMIC somatic mutation

Mutation (CDS; AA; Chr)

Site

Histology

Mutation Type

c.643G>A; p.V215M; 16:67436121-67436121

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.1017C>G; p.Y339*; 16:67436802-67436802

 livercarcinoma; hepatocellular_carcinomaSubstitution - Nonsense

c.1017C>G; p.Y339*; 16:67436802-67436802

 livercarcinoma; hepatocellular_carcinomaSubstitution - Nonsense

c.850C>T; p.L284L; 16:67436635-67436635

 kidneyother; neoplasmSubstitution - coding silent

c.1007G>A; p.R336H; 16:67436792-67436792

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.698G>T; p.G233V; 16:67436282-67436282

 breastcarcinomaSubstitution - Missense

c.1082G>A; p.R361H; 16:67436867-67436867

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Missense

c.336C>T; p.T112T; 16:67435698-67435698

 lungcarcinoma; small_cell_carcinomaSubstitution - coding silent

c.880G>C; p.A294P; 16:67436665-67436665

 livercarcinomaSubstitution - Missense

c.880G>C; p.A294P; 16:67436665-67436665

 livercarcinomaSubstitution - Missense

c.934C>T; p.R312C; 16:67436719-67436719

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.656G>A; p.S219N; 16:67436134-67436134

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.708A>C; p.K236N; 16:67436292-67436292

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.518T>C; p.V173A; 16:67435996-67435996

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.704C>T; p.S235F; 16:67436288-67436288

 breastcarcinomaSubstitution - Missense

c.1076G>A; p.R359Q; 16:67436861-67436861

 livercarcinomaSubstitution - Missense

c.1076G>A; p.R359Q; 16:67436861-67436861

 livercarcinomaSubstitution - Missense

c.971C>A; p.A324D; 16:67436756-67436756

 upper_aerodigestive_tract; pharynxcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.587C>T; p.A196V; 16:67436065-67436065

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.759G>A; p.W253*; 16:67436343-67436343

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Nonsense

c.1116G>A; p.L372L; 16:67436901-67436901

 urinary_tract; bladdercarcinomaSubstitution - coding silent

c.468C>A; p.T156T; 16:67435830-67435830

 thyroidother; neoplasmSubstitution - coding silent

c.586G>A; p.A196T; 16:67436064-67436064

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.781C>A; p.Q261K; 16:67436365-67436365

 skinmalignant_melanomaSubstitution - Missense

c.829G>A; p.E277K; 16:67436614-67436614

 skinmalignant_melanomaSubstitution - Missense

c.921C>G; p.F307L; 16:67436706-67436706

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.1074G>A; p.L358L; 16:67436859-67436859

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - coding silent

c.713C>T; p.A238V; 16:67436297-67436297

 livercarcinomaSubstitution - Missense

c.1125A>G; p.A375A; 16:67436910-67436910

 stomachcarcinoma; adenocarcinomaSubstitution - coding silent

c.713C>T; p.A238V; 16:67436297-67436297

 livercarcinomaSubstitution - Missense

c.1059C>T; p.Y353Y; 16:67436844-67436844

 stomachcarcinoma; adenocarcinomaSubstitution - coding silent

c.912T>C; p.H304H; 16:67436697-67436697

 oesophagus; lower_thirdcarcinoma; adenocarcinomaSubstitution - coding silent

c.440G>A; p.R147H; 16:67435802-67435802

 oesophaguscarcinoma; adenocarcinomaSubstitution - Missense

c.1020C>A; p.P340P; 16:67436805-67436805

 lungcarcinoma; adenocarcinomaSubstitution - coding silent

c.945G>A; p.M315I; 16:67436730-67436730

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.665-4G>T; p.?; 16:67436245-67436245

 pancreascarcinomaUnknown

c.354C>T; p.S118S; 16:67435716-67435716

 large_intestinecarcinoma; adenocarcinomaSubstitution - coding silent

c.1079G>A; p.R360H; 16:67436864-67436864

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.1079G>A; p.R360H; 16:67436864-67436864

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.1064C>T; p.P355L; 16:67436849-67436849

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.585C>T; p.G195G; 16:67436063-67436063

 large_intestinecarcinoma; adenocarcinomaSubstitution - coding silent

c.1161G>T; p.Q387H; 16:67436946-67436946

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.616C>T; p.L206L; 16:67436094-67436094

 stomachcarcinoma; adenocarcinomaSubstitution - coding silent