lung cancer gene and literature database Home

Annotation category 5

Basic annotation
Ontology and pathways
Literature evidence
Curated literatures
Expression
Gene expression chart
Somatic mutation
COSMIC and TCGA mutations
Network
Gene interaction
ceRNA
Gene-related ceRNA

Gene information

Gene ID	3181
Symbol	HNRNPA2B1
Synonymous	HNRNPA2\|HNRNPB1\|HNRPA2\|HNRPA2B1\|HNRPB1\|IBMPFD2\|RNPA2\|SNRPB1
Full name	heterogeneous nuclear ribonucleoprotein A2/B1
Gene description	heterogeneous nuclear ribonucleoproteins A2/B1\|hnRNP A2 / hnRNP B1\|nuclear ribonucleoprotein particle A2 protein
Cytoband	7p15
Gene type	protein-coding
Synonymous	MIM:600124; HGNC:HGNC:5033; Ensembl:ENSG00000122566; HPRD:02526; Vega:OTTHUMG00000023471

COSMIC somatic mutation

Mutation (CDS; AA; Chr)	Site	Histology	Mutation Type
c.363G>T; p.E121D; 7:26196919-26196919	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.757G>A; p.G253R; 7:26193659-26193659	skin	malignant_melanoma	Substitution - Missense
c.413G>A; p.G138E; 7:26196869-26196869	thyroid	other; neoplasm	Substitution - Missense
c.334G>C; p.E112Q; 7:26196948-26196948	breast	carcinoma	Substitution - Missense
c.10G>A; p.E4K; 7:26197729-26197729	breast	carcinoma	Substitution - Missense
c.186G>C; p.E62D; 7:26197393-26197393	kidney	other; neoplasm	Substitution - Missense
c.241C>T; p.P81S; 7:26197338-26197338	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1012A>G; p.R338G; 7:26192530-26192530	breast	carcinoma	Substitution - Missense
c.532A>G; p.R178G; 7:26196602-26196602	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.781G>T; p.G261*; 7:26193635-26193635	liver	carcinoma	Substitution - Nonsense
c.287A>C; p.H96P; 7:26196995-26196995	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.4G>A; p.E2K; 7:26200574-26200574	skin; upper_leg	malignant_melanoma	Substitution - Missense
c.662G>C; p.G221A; 7:26195906-26195906	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.524C>T; p.A175V; 7:26196610-26196610	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.592G>A; p.G198R; 7:26196467-26196467	skin; mucosal	malignant_melanoma	Substitution - Missense
c.422G>C; p.R141T; 7:26196860-26196860	urinary_tract; bladder	carcinoma	Substitution - Missense
c.676C>A; p.R226S; 7:26195892-26195892	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.802G>T; p.G268C; 7:26193614-26193614	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.463G>C; p.D155H; 7:26196819-26196819	ovary	other; neoplasm	Substitution - Missense
c.463G>C; p.D155H; 7:26196819-26196819	ovary	other; neoplasm	Substitution - Missense
c.123G>C; p.M41I; 7:26197456-26197456	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.733G>T; p.G245*; 7:26193683-26193683	breast	carcinoma	Substitution - Nonsense
c.651A>G; p.G217G; 7:26196408-26196408	liver	carcinoma	Substitution - coding silent
c.651A>G; p.G217G; 7:26196408-26196408	liver	carcinoma	Substitution - coding silent
c.296_297delTG; p.V99fs*9; 7:26196985-26196986	skin; upper_leg	malignant_melanoma	Deletion - Frameshift
c.200T>C; p.M67T; 7:26197379-26197379	genital_tract; extragonadal	germ_cell_tumour; seminoma	Substitution - Missense
c.404G>A; p.R135K; 7:26196878-26196878	skin	malignant_melanoma	Substitution - Missense
c.642C>A; p.N214K; 7:26196417-26196417	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.361G>C; p.E121Q; 7:26196921-26196921	urinary_tract; bladder	carcinoma	Substitution - Missense
c.813C>T; p.Y271Y; 7:26193603-26193603	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.810C>G; p.G270G; 7:26193606-26193606	ovary	carcinoma; serous_carcinoma	Substitution - coding silent
c.78G>A; p.R26R; 7:26197661-26197661	urinary_tract; bladder	carcinoma	Substitution - coding silent
c.927delT; p.F309fs*>33; 7:26193288-26193288	liver	carcinoma	Deletion - Frameshift
c.88G>C; p.E30Q; 7:26197651-26197651	breast	carcinoma	Substitution - Missense
c.875G>A; p.G292E; 7:26193340-26193340	skin	malignant_melanoma	Substitution - Missense
c.568G>A; p.G190R; 7:26196566-26196566	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.268T>G; p.S90A; 7:26197014-26197014	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.718G>C; p.G240R; 7:26195850-26195850	skin	malignant_melanoma	Substitution - Missense
c.833A>G; p.Y278C; 7:26193583-26193583	breast	carcinoma	Substitution - Missense
c.679G>A; p.G227R; 7:26195889-26195889	kidney	carcinoma; papillary_renal_cell_carcinoma	Substitution - Missense
c.915G>C; p.K305N; 7:26193300-26193300	breast	carcinoma	Substitution - Missense
c.915G>C; p.K305N; 7:26193300-26193300	upper_aerodigestive_tract; mouth	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.297G>A; p.V99V; 7:26196985-26196985	prostate	adenoma	Substitution - coding silent
c.529T>C; p.S177P; 7:26196605-26196605	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.158G>T; p.G53V; 7:26197421-26197421	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.875G>C; p.G292A; 7:26193340-26193340	upper_aerodigestive_tract; mouth	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.739A>T; p.S247C; 7:26193677-26193677	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.276A>C; p.K92N; 7:26197006-26197006	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.676C>T; p.R226C; 7:26195892-26195892	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.743_744CC>TT; p.P248L; 7:26193672-26193673	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.238G>C; p.E80Q; 7:26197341-26197341	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.727A>T; p.N243Y; 7:26193689-26193689	lung; right_lower_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.50G>A; p.S17N; 7:26197689-26197689	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.538G>A; p.E180K; 7:26196596-26196596	skin	malignant_melanoma	Substitution - Missense
c.473T>C; p.V158A; 7:26196809-26196809	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.473T>C; p.V158A; 7:26196809-26196809	large_intestine; colon	carcinoma	Substitution - Missense
c.473T>C; p.V158A; 7:26196809-26196809	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.674G>T; p.G225V; 7:26195894-26195894	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.523G>A; p.A175T; 7:26196611-26196611	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.200T>G; p.M67R; 7:26197379-26197379	central_nervous_system; medulla	primitive_neuroectodermal_tumour-medulloblastoma; classic	Substitution - Missense
c.977C>T; p.P326L; 7:26192565-26192565	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.817G>A; p.G273S; 7:26193599-26193599	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.975T>C; p.G325G; 7:26192567-26192567	skin	malignant_melanoma	Substitution - coding silent
c.460G>A; p.V154M; 7:26196822-26196822	urinary_tract; bladder	carcinoma; transitional_cell_carcinoma	Substitution - Missense
c.460G>A; p.V154M; 7:26196822-26196822	urinary_tract; bladder	carcinoma	Substitution - Missense
c.946G>T; p.G316W; 7:26193269-26193269	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.464A>G; p.D155G; 7:26196818-26196818	liver	carcinoma; hepatocellular_carcinoma	Substitution - Missense
c.464A>G; p.D155G; 7:26196818-26196818	liver	carcinoma	Substitution - Missense
c.950delG; p.G317fs*>25; 7:26193265-26193265	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.950delG; p.G317fs*>25; 7:26193265-26193265	liver	carcinoma; hepatocellular_carcinoma	Deletion - Frameshift
c.950delG; p.G317fs*>25; 7:26193265-26193265	liver	carcinoma	Deletion - Frameshift
c.149G>T; p.R50I; 7:26197430-26197430	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.393A>G; p.I131M; 7:26196889-26196889	urinary_tract; bladder	carcinoma	Substitution - Missense
c.576_577+1delAGG; p.?; 7:26196556-26196558	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Unknown
c.206C>G; p.A69G; 7:26197373-26197373	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense

Annotation category 5

Basic annotation

Literature evidence

Expression

Somatic mutation

Network

ceRNA

Gene information

COSMIC somatic mutation