lung cancer gene and literature database Home

Annotation category 5

Basic annotation
Ontology and pathways
Literature evidence
Curated literatures
Expression
Gene expression chart
Somatic mutation
COSMIC and TCGA mutations
Network
Gene interaction
ceRNA
Gene-related ceRNA

Gene information

Gene ID	3106
Symbol	HLA-B
Synonymous	AS\|HLAB\|SPDA1
Full name	major histocompatibility complex, class I, B
Gene description	HLA class I histocompatibility antigen, B alpha chain\|MHC Class I HLA heavy chain\|MHC HLA-B cell surface glycoprotein\|MHC HLA-B transmembrane glycoprotein\|MHC class I antigen GN00104\|MHC class I antigen HLA-B heavy chain\|MHC class I antigen SHCHA\|leukocyt
Cytoband	6p21.3
Gene type	protein-coding
Synonymous	MIM:142830; HGNC:HGNC:4932; Ensembl:ENSG00000234745; HPRD:00828; Vega:OTTHUMG00000031153

COSMIC somatic mutation

Mutation (CDS; AA; Chr)	Site	Histology	Mutation Type
c.618T>G; p.A206A; 6:31356168-31356168	urinary_tract; bladder	carcinoma	Substitution - coding silent
c.618T>G; p.A206A; 6:31356168-31356168	thyroid	other; neoplasm	Substitution - coding silent
c.618T>G; p.A206A; 6:31356168-31356168	thyroid	other; neoplasm	Substitution - coding silent
c.618T>G; p.A206A; 6:31356168-31356168	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.363C>G; p.S121R; 6:31356423-31356423	thyroid	other; neoplasm	Substitution - Missense
c.272A>C; p.Y91S; 6:31356759-31356759	thyroid	other; neoplasm	Substitution - Missense
c.272A>C; p.Y91S; 6:31356759-31356759	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.272A>C; p.Y91S; 6:31356759-31356759	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.272A>C; p.Y91S; 6:31356759-31356759	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.272A>C; p.Y91S; 6:31356759-31356759	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.272A>C; p.Y91S; 6:31356759-31356759	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.272A>C; p.Y91S; 6:31356759-31356759	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.252G>A; p.W84*; 6:31356779-31356779	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Nonsense
c.272A>C; p.Y91S; 6:31356759-31356759	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.272A>C; p.Y91S; 6:31356759-31356759	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.261C>G; p.N87K; 6:31356770-31356770	thyroid	other; neoplasm	Substitution - Missense
c.261C>G; p.N87K; 6:31356770-31356770	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; plasma_cell_myeloma	Substitution - Missense
c.635_636delAC; p.H212fs*8; 6:31355576-31355577	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.756T>C; p.T252T; 6:31355456-31355456	thyroid	other; neoplasm	Substitution - coding silent
c.48C>A; p.A16A; 6:31357111-31357111	liver	carcinoma; hepatocellular_carcinoma	Substitution - coding silent
c.603C>G; p.D201E; 6:31356183-31356183	pancreas	carcinoma; ductal_carcinoma	Substitution - Missense
c.603C>G; p.D201E; 6:31356183-31356183	thyroid	other; neoplasm	Substitution - Missense
c.603C>G; p.D201E; 6:31356183-31356183	pancreas	pancreatic_intraepithelial_neoplasia_(PanIN)	Substitution - Missense
c.603C>G; p.D201E; 6:31356183-31356183	thyroid	other; neoplasm	Substitution - Missense
c.603C>G; p.D201E; 6:31356183-31356183	pancreas	pancreatic_intraepithelial_neoplasia_(PanIN)	Substitution - Missense
c.486G>C; p.T162T; 6:31356300-31356300	thyroid	other; neoplasm	Substitution - coding silent
c.486G>C; p.T162T; 6:31356300-31356300	thyroid	other; neoplasm	Substitution - coding silent
c.486G>C; p.T162T; 6:31356300-31356300	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.256C>G; p.R86G; 6:31356775-31356775	urinary_tract; bladder	carcinoma	Substitution - Missense
c.739G>A; p.D247N; 6:31355473-31355473	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.933_934insT; p.V312fs*22; 6:31355185-31355186	large_intestine; colon	carcinoma; adenocarcinoma	Insertion - Frameshift
c.797A>G; p.Q266R; 6:31355415-31355415	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.356T>G; p.L119R; 6:31356430-31356430	thyroid	other; neoplasm	Substitution - Missense
c.356T>G; p.L119R; 6:31356430-31356430	thyroid	other; neoplasm	Substitution - Missense
c.893_894GG>AA; p.W298*; 6:31355318-31355319	upper_aerodigestive_tract; mouth	carcinoma; squamous_cell_carcinoma	Substitution - Nonsense
c.278C>G; p.A93G; 6:31356753-31356753	urinary_tract; bladder	carcinoma	Substitution - Missense
c.278C>G; p.A93G; 6:31356753-31356753	urinary_tract; bladder	carcinoma	Substitution - Missense
c.49C>G; p.L17V; 6:31357110-31357110	liver	carcinoma; hepatocellular_carcinoma	Substitution - Missense
c.97T>G; p.Y33D; 6:31356934-31356934	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.97T>G; p.Y33D; 6:31356934-31356934	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.97T>G; p.Y33D; 6:31356934-31356934	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1043C>T; p.A348V; 6:31354635-31354635	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.97T>G; p.Y33D; 6:31356934-31356934	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.105C>T; p.S35S; 6:31356926-31356926	urinary_tract; bladder	carcinoma	Substitution - coding silent
c.97T>G; p.Y33D; 6:31356934-31356934	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.424T>C; p.Y142H; 6:31356362-31356362	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.538_539delCG; p.R180fs*27; 6:31356247-31356248	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.559G>C; p.E187Q; 6:31356227-31356227	thyroid	other; neoplasm	Substitution - Missense
c.559G>C; p.E187Q; 6:31356227-31356227	thyroid	other; neoplasm	Substitution - Missense
c.559G>C; p.E187Q; 6:31356227-31356227	thyroid	other; neoplasm	Substitution - Missense
c.559G>C; p.E187Q; 6:31356227-31356227	pancreas	pancreatic_intraepithelial_neoplasia_(PanIN)	Substitution - Missense
c.559G>C; p.E187Q; 6:31356227-31356227	pancreas	pancreatic_intraepithelial_neoplasia_(PanIN)	Substitution - Missense
c.11T>C; p.M4T; 6:31357148-31357148	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.11T>C; p.M4T; 6:31357148-31357148	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.11T>C; p.M4T; 6:31357148-31357148	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.11T>C; p.M4T; 6:31357148-31357148	thyroid	other; neoplasm	Substitution - Missense
c.11T>C; p.M4T; 6:31357148-31357148	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.11T>C; p.M4T; 6:31357148-31357148	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.11T>C; p.M4T; 6:31357148-31357148	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.11T>C; p.M4T; 6:31357148-31357148	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.11T>C; p.M4T; 6:31357148-31357148	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.11T>C; p.M4T; 6:31357148-31357148	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.11T>C; p.M4T; 6:31357148-31357148	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.11T>C; p.M4T; 6:31357148-31357148	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.11T>C; p.M4T; 6:31357148-31357148	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.11T>C; p.M4T; 6:31357148-31357148	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.11T>C; p.M4T; 6:31357148-31357148	upper_aerodigestive_tract; mouth	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.11T>C; p.M4T; 6:31357148-31357148	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.11T>C; p.M4T; 6:31357148-31357148	thyroid	other; neoplasm	Substitution - Missense
c.11T>C; p.M4T; 6:31357148-31357148	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.11T>C; p.M4T; 6:31357148-31357148	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.11T>C; p.M4T; 6:31357148-31357148	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.757G>A; p.E253K; 6:31355455-31355455	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.319G>C; p.G107R; 6:31356712-31356712	thyroid	other; neoplasm	Substitution - Missense
c.319G>C; p.G107R; 6:31356712-31356712	thyroid	other; neoplasm	Substitution - Missense
c.895+1G>T; p.?; 6:31355316-31355316	large_intestine; colon	carcinoma; adenocarcinoma	Unknown
c.873G>A; p.P291P; 6:31355339-31355339	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - coding silent
c.649C>T; p.P217S; 6:31355563-31355563	skin	malignant_melanoma	Substitution - Missense
c.206A>T; p.E69V; 6:31356825-31356825	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.206A>T; p.E69V; 6:31356825-31356825	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.722G>A; p.W241*; 6:31355490-31355490	pancreas	carcinoma	Substitution - Nonsense
c.527A>T; p.E176V; 6:31356259-31356259	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.527A>T; p.E176V; 6:31356259-31356259	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.527A>T; p.E176V; 6:31356259-31356259	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.265_266delCA; p.Q89fs*9; 6:31356765-31356766	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.167A>T; p.Q56L; 6:31356864-31356864	thyroid	other; neoplasm	Substitution - Missense
c.735C>G; p.G245G; 6:31355477-31355477	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - coding silent
c.527A>T; p.E176V; 6:31356259-31356259	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.527A>T; p.E176V; 6:31356259-31356259	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.527A>T; p.E176V; 6:31356259-31356259	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.527A>T; p.E176V; 6:31356259-31356259	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.527A>T; p.E176V; 6:31356259-31356259	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.527A>T; p.E176V; 6:31356259-31356259	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.527A>T; p.E176V; 6:31356259-31356259	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.527A>T; p.E176V; 6:31356259-31356259	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.527A>T; p.E176V; 6:31356259-31356259	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.527A>T; p.E176V; 6:31356259-31356259	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.527A>T; p.E176V; 6:31356259-31356259	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.527A>T; p.E176V; 6:31356259-31356259	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.527A>T; p.E176V; 6:31356259-31356259	thyroid	other; neoplasm	Substitution - Missense
c.527A>T; p.E176V; 6:31356259-31356259	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.527A>T; p.E176V; 6:31356259-31356259	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.527A>T; p.E176V; 6:31356259-31356259	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.527A>T; p.E176V; 6:31356259-31356259	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.527A>T; p.E176V; 6:31356259-31356259	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.206A>C; p.E69A; 6:31356825-31356825	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.206A>C; p.E69A; 6:31356825-31356825	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.206A>C; p.E69A; 6:31356825-31356825	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.206A>C; p.E69A; 6:31356825-31356825	thyroid	other; neoplasm	Substitution - Missense
c.206A>C; p.E69A; 6:31356825-31356825	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.206A>C; p.E69A; 6:31356825-31356825	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.206A>C; p.E69A; 6:31356825-31356825	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.206A>C; p.E69A; 6:31356825-31356825	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.700C>G; p.P234A; 6:31355512-31355512	haematopoietic_and_lymphoid_tissue; lymph_node	lymphoid_neoplasm; diffuse_large_B_cell_lymphoma	Substitution - Missense
c.206A>C; p.E69A; 6:31356825-31356825	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.206A>C; p.E69A; 6:31356825-31356825	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.206A>C; p.E69A; 6:31356825-31356825	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.206A>C; p.E69A; 6:31356825-31356825	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.5T>G; p.L2R; 6:31357154-31357154	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.5T>G; p.L2R; 6:31357154-31357154	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.5T>G; p.L2R; 6:31357154-31357154	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.5T>G; p.L2R; 6:31357154-31357154	thyroid	other; neoplasm	Substitution - Missense
c.5T>G; p.L2R; 6:31357154-31357154	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.5T>G; p.L2R; 6:31357154-31357154	thyroid	other; neoplasm	Substitution - Missense
c.5T>G; p.L2R; 6:31357154-31357154	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.5T>G; p.L2R; 6:31357154-31357154	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.5T>G; p.L2R; 6:31357154-31357154	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.5T>G; p.L2R; 6:31357154-31357154	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.5T>G; p.L2R; 6:31357154-31357154	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.420C>A; p.Y140*; 6:31356366-31356366	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Nonsense
c.420C>A; p.Y140*; 6:31356366-31356366	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Nonsense
c.5T>G; p.L2R; 6:31357154-31357154	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.420C>A; p.Y140*; 6:31356366-31356366	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Nonsense
c.5T>G; p.L2R; 6:31357154-31357154	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.5T>G; p.L2R; 6:31357154-31357154	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.5T>G; p.L2R; 6:31357154-31357154	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.5T>G; p.L2R; 6:31357154-31357154	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.420C>A; p.Y140*; 6:31356366-31356366	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Nonsense
c.5T>G; p.L2R; 6:31357154-31357154	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.5T>G; p.L2R; 6:31357154-31357154	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.5T>G; p.L2R; 6:31357154-31357154	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.773G>A; p.R258K; 6:31355439-31355439	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.204A>G; p.R68R; 6:31356827-31356827	thyroid	other; neoplasm	Substitution - coding silent
c.204A>G; p.R68R; 6:31356827-31356827	thyroid	other; neoplasm	Substitution - coding silent
c.654C>T; p.I218I; 6:31355558-31355558	thyroid	carcinoma	Substitution - coding silent
c.907C>T; p.Q303*; 6:31355212-31355212	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Nonsense
c.736G>A; p.E246K; 6:31355476-31355476	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.343+1G>A; p.?; 6:31356687-31356687	upper_aerodigestive_tract; mouth	carcinoma; squamous_cell_carcinoma	Unknown
c.907C>T; p.Q303*; 6:31355212-31355212	skin	malignant_melanoma	Substitution - Nonsense
c.343+1G>A; p.?; 6:31356687-31356687	large_intestine; caecum	carcinoma; adenocarcinoma	Unknown
c.320_321insCC; p.Y108fs*44; 6:31356710-31356711	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Insertion - Frameshift
c.418T>G; p.Y140D; 6:31356368-31356368	liver	carcinoma; hepatocellular_carcinoma	Substitution - Missense
c.280C>A; p.Q94K; 6:31356751-31356751	thyroid	other; neoplasm	Substitution - Missense
c.206_207insC; p.E69fs*30; 6:31356824-31356825	large_intestine; rectum	carcinoma; adenocarcinoma	Insertion - Frameshift
c.206_207insC; p.E69fs*30; 6:31356824-31356825	breast	carcinoma	Insertion - Frameshift
c.206_207insC; p.E69fs*30; 6:31356824-31356825	large_intestine; colon	carcinoma; adenocarcinoma	Insertion - Frameshift
c.206_207insC; p.E69fs*30; 6:31356824-31356825	breast	carcinoma	Insertion - Frameshift
c.280C>A; p.Q94K; 6:31356751-31356751	thyroid	other; neoplasm	Substitution - Missense
c.206_207insC; p.E69fs*30; 6:31356824-31356825	breast	carcinoma	Insertion - Frameshift
c.1047C>G; p.C349W; 6:31354525-31354525	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.463C>A; p.R155S; 6:31356323-31356323	urinary_tract; bladder	carcinoma	Substitution - Missense
c.463C>A; p.R155S; 6:31356323-31356323	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.463C>A; p.R155S; 6:31356323-31356323	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.463C>A; p.R155S; 6:31356323-31356323	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1047C>G; p.C349W; 6:31354525-31354525	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.463C>A; p.R155S; 6:31356323-31356323	thyroid	other; neoplasm	Substitution - Missense
c.463C>A; p.R155S; 6:31356323-31356323	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1047C>G; p.C349W; 6:31354525-31354525	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.463C>A; p.R155S; 6:31356323-31356323	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.463C>A; p.R155S; 6:31356323-31356323	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.463C>A; p.R155S; 6:31356323-31356323	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.463C>A; p.R155S; 6:31356323-31356323	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.463C>A; p.R155S; 6:31356323-31356323	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1047C>G; p.C349W; 6:31354525-31354525	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.1047C>G; p.C349W; 6:31354525-31354525	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.1047C>G; p.C349W; 6:31354525-31354525	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.463C>A; p.R155S; 6:31356323-31356323	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1047C>G; p.C349W; 6:31354525-31354525	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.463C>A; p.R155S; 6:31356323-31356323	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1047C>G; p.C349W; 6:31354525-31354525	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.463C>A; p.R155S; 6:31356323-31356323	thyroid	other; neoplasm	Substitution - Missense
c.463C>A; p.R155S; 6:31356323-31356323	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1047C>G; p.C349W; 6:31354525-31354525	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.463C>A; p.R155S; 6:31356323-31356323	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.463C>A; p.R155S; 6:31356323-31356323	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1047C>G; p.C349W; 6:31354525-31354525	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.1047C>G; p.C349W; 6:31354525-31354525	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.463C>A; p.R155S; 6:31356323-31356323	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.463C>A; p.R155S; 6:31356323-31356323	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.283G>A; p.A95T; 6:31356748-31356748	thyroid	other; neoplasm	Substitution - Missense
c.842A>G; p.Y281C; 6:31355370-31355370	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.19C>T; p.R7*; 6:31357140-31357140	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Nonsense
c.283G>A; p.A95T; 6:31356748-31356748	thyroid	other; neoplasm	Substitution - Missense
c.283G>A; p.A95T; 6:31356748-31356748	thyroid	other; neoplasm	Substitution - Missense
c.311delA; p.N104fs*47; 6:31356720-31356720	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Deletion - Frameshift
c.19C>T; p.R7*; 6:31357140-31357140	oesophagus	carcinoma; adenocarcinoma	Substitution - Nonsense
c.539G>T; p.R180L; 6:31356247-31356247	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.539G>T; p.R180L; 6:31356247-31356247	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.539G>T; p.R180L; 6:31356247-31356247	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.911C>G; p.S304C; 6:31355208-31355208	breast	carcinoma	Substitution - Missense
c.1012G>A; p.G338S; 6:31355107-31355107	skin	malignant_melanoma	Substitution - Missense
c.539G>T; p.R180L; 6:31356247-31356247	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.539G>T; p.R180L; 6:31356247-31356247	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.539G>T; p.R180L; 6:31356247-31356247	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.539G>T; p.R180L; 6:31356247-31356247	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.539G>T; p.R180L; 6:31356247-31356247	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.539G>T; p.R180L; 6:31356247-31356247	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.539G>T; p.R180L; 6:31356247-31356247	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.539G>T; p.R180L; 6:31356247-31356247	thyroid	other; neoplasm	Substitution - Missense
c.539G>T; p.R180L; 6:31356247-31356247	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.149G>A; p.G50D; 6:31356882-31356882	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.539G>T; p.R180L; 6:31356247-31356247	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.539G>T; p.R180L; 6:31356247-31356247	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.144A>C; p.S48S; 6:31356887-31356887	urinary_tract; bladder	carcinoma	Substitution - coding silent
c.539G>T; p.R180L; 6:31356247-31356247	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.539G>T; p.R180L; 6:31356247-31356247	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.272A>T; p.Y91F; 6:31356759-31356759	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.693T>C; p.G231G; 6:31355519-31355519	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - coding silent
c.272A>T; p.Y91F; 6:31356759-31356759	thyroid	other; neoplasm	Substitution - Missense
c.880C>T; p.L294F; 6:31355332-31355332	thyroid	other; neoplasm	Substitution - Missense
c.355C>T; p.L119F; 6:31356431-31356431	thyroid	other; neoplasm	Substitution - Missense
c.861T>C; p.H287H; 6:31355351-31355351	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - coding silent
c.355C>T; p.L119F; 6:31356431-31356431	thyroid	other; neoplasm	Substitution - Missense
c.861T>C; p.H287H; 6:31355351-31355351	thyroid	other; neoplasm	Substitution - coding silent
c.861T>C; p.H287H; 6:31355351-31355351	thyroid	other; neoplasm	Substitution - coding silent
c.240delG; p.P81fs*70; 6:31356791-31356791	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.981C>T; p.V327V; 6:31355138-31355138	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.771C>G; p.T257T; 6:31355441-31355441	skin	malignant_melanoma	Substitution - coding silent
c.453C>T; p.N151N; 6:31356333-31356333	thyroid	other; neoplasm	Substitution - coding silent
c.354C>T; p.T118T; 6:31356432-31356432	thyroid	other; neoplasm	Substitution - coding silent
c.354C>T; p.T118T; 6:31356432-31356432	thyroid	other; neoplasm	Substitution - coding silent
c.986C>T; p.A329V; 6:31355133-31355133	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.986C>T; p.A329V; 6:31355133-31355133	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.848G>A; p.C283Y; 6:31355364-31355364	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.986C>T; p.A329V; 6:31355133-31355133	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.319G>T; p.G107C; 6:31356712-31356712	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.38T>C; p.L13P; 6:31357121-31357121	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.986C>T; p.A329V; 6:31355133-31355133	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.874A>G; p.K292E; 6:31355338-31355338	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.874A>G; p.K292E; 6:31355338-31355338	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.874A>G; p.K292E; 6:31355338-31355338	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.874A>G; p.K292E; 6:31355338-31355338	thyroid	other; neoplasm	Substitution - Missense
c.874A>G; p.K292E; 6:31355338-31355338	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.874A>G; p.K292E; 6:31355338-31355338	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.874A>G; p.K292E; 6:31355338-31355338	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.874A>G; p.K292E; 6:31355338-31355338	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.874A>G; p.K292E; 6:31355338-31355338	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.874A>G; p.K292E; 6:31355338-31355338	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.874A>G; p.K292E; 6:31355338-31355338	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.874A>G; p.K292E; 6:31355338-31355338	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.15G>A; p.A5A; 6:31357144-31357144	upper_aerodigestive_tract; mouth	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.874A>G; p.K292E; 6:31355338-31355338	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.874A>G; p.K292E; 6:31355338-31355338	thyroid	other; neoplasm	Substitution - Missense
c.874A>G; p.K292E; 6:31355338-31355338	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.874A>G; p.K292E; 6:31355338-31355338	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.595_596GG>AA; p.G199K; 6:31356190-31356191	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.301A>G; p.S101G; 6:31356730-31356730	thyroid	other; neoplasm	Substitution - Missense
c.589G>A; p.E197K; 6:31356197-31356197	breast	carcinoma	Substitution - Missense
c.259A>G; p.N87D; 6:31356772-31356772	thyroid	other; neoplasm	Substitution - Missense
c.259A>G; p.N87D; 6:31356772-31356772	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; plasma_cell_myeloma	Substitution - Missense
c.589G>A; p.E197K; 6:31356197-31356197	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.589G>A; p.E197K; 6:31356197-31356197	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.205G>A; p.E69K; 6:31356826-31356826	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.205G>A; p.E69K; 6:31356826-31356826	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.205G>A; p.E69K; 6:31356826-31356826	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.205G>A; p.E69K; 6:31356826-31356826	thyroid	other; neoplasm	Substitution - Missense
c.205G>A; p.E69K; 6:31356826-31356826	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.205G>A; p.E69K; 6:31356826-31356826	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.205G>A; p.E69K; 6:31356826-31356826	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.205G>A; p.E69K; 6:31356826-31356826	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.205G>A; p.E69K; 6:31356826-31356826	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.205G>A; p.E69K; 6:31356826-31356826	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.205G>A; p.E69K; 6:31356826-31356826	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.205G>A; p.E69K; 6:31356826-31356826	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.205G>A; p.E69K; 6:31356826-31356826	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.205G>A; p.E69K; 6:31356826-31356826	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1002G>A; p.R334R; 6:31355117-31355117	urinary_tract; bladder	carcinoma	Substitution - coding silent
c.872C>A; p.P291Q; 6:31355340-31355340	thyroid	other; neoplasm	Substitution - Missense
c.881T>G; p.L294R; 6:31355331-31355331	thyroid	other; neoplasm	Substitution - Missense
c.401_403delTCC; p.L134delL; 6:31356383-31356385	large_intestine; caecum	carcinoma; adenocarcinoma	Deletion - In frame
c.668C>T; p.A223V; 6:31355544-31355544	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.846A>G; p.T282T; 6:31355366-31355366	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - coding silent
c.266A>G; p.Q89R; 6:31356765-31356765	upper_aerodigestive_tract; mouth	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.846A>G; p.T282T; 6:31355366-31355366	thyroid	other; neoplasm	Substitution - coding silent
c.369C>T; p.Y123Y; 6:31356417-31356417	thyroid	other; neoplasm	Substitution - coding silent
c.369C>T; p.Y123Y; 6:31356417-31356417	urinary_tract; bladder	carcinoma	Substitution - coding silent
c.846A>G; p.T282T; 6:31355366-31355366	thyroid	other; neoplasm	Substitution - coding silent
c.568G>T; p.E190*; 6:31356218-31356218	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Nonsense
c.863A>T; p.E288V; 6:31355349-31355349	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.213G>C; p.P71P; 6:31356818-31356818	thyroid	other; neoplasm	Substitution - coding silent
c.213G>C; p.P71P; 6:31356818-31356818	urinary_tract; bladder	carcinoma	Substitution - coding silent
c.213G>C; p.P71P; 6:31356818-31356818	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.213G>C; p.P71P; 6:31356818-31356818	thyroid	other; neoplasm	Substitution - coding silent
c.610G>C; p.E204Q; 6:31356176-31356176	urinary_tract; bladder	carcinoma	Substitution - Missense
c.610G>C; p.E204Q; 6:31356176-31356176	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.610G>C; p.E204Q; 6:31356176-31356176	thyroid	other; neoplasm	Substitution - Missense
c.610G>C; p.E204Q; 6:31356176-31356176	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.610G>C; p.E204Q; 6:31356176-31356176	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.610G>C; p.E204Q; 6:31356176-31356176	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.610G>C; p.E204Q; 6:31356176-31356176	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.610G>C; p.E204Q; 6:31356176-31356176	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.240G>T; p.G80G; 6:31356791-31356791	breast	carcinoma	Substitution - coding silent
c.610G>C; p.E204Q; 6:31356176-31356176	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.610G>C; p.E204Q; 6:31356176-31356176	thyroid	other; neoplasm	Substitution - Missense
c.610G>C; p.E204Q; 6:31356176-31356176	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.610G>C; p.E204Q; 6:31356176-31356176	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.610G>C; p.E204Q; 6:31356176-31356176	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.610G>C; p.E204Q; 6:31356176-31356176	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.485C>A; p.T162K; 6:31356301-31356301	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.617_618delCT; p.A206fs*14; 6:31356168-31356169	stomach	carcinoma; intestinal_adenocarcinoma	Deletion - Frameshift
c.1047C>T; p.C349C; 6:31354525-31354525	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - coding silent
c.485C>A; p.T162K; 6:31356301-31356301	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.485C>A; p.T162K; 6:31356301-31356301	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.485C>A; p.T162K; 6:31356301-31356301	pancreas	pancreatic_intraepithelial_neoplasia_(PanIN)	Substitution - Missense
c.485C>A; p.T162K; 6:31356301-31356301	pancreas	carcinoma; ductal_carcinoma	Substitution - Missense
c.485C>A; p.T162K; 6:31356301-31356301	pancreas	pancreatic_intraepithelial_neoplasia_(PanIN)	Substitution - Missense
c.459C>T; p.D153D; 6:31356327-31356327	breast	carcinoma	Substitution - coding silent
c.650C>T; p.P217L; 6:31355562-31355562	central_nervous_system; brainstem	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.459C>T; p.D153D; 6:31356327-31356327	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - coding silent
c.228A>G; p.I76M; 6:31356803-31356803	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.228A>G; p.I76M; 6:31356803-31356803	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.228A>G; p.I76M; 6:31356803-31356803	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.774A>G; p.R258R; 6:31355438-31355438	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - coding silent
c.193G>A; p.A65T; 6:31356838-31356838	thyroid	other; neoplasm	Substitution - Missense
c.193G>A; p.A65T; 6:31356838-31356838	thyroid	other; neoplasm	Substitution - Missense
c.774A>G; p.R258R; 6:31355438-31355438	thyroid	other; neoplasm	Substitution - coding silent
c.309G>C; p.R103R; 6:31356722-31356722	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.774A>G; p.R258R; 6:31355438-31355438	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.412G>C; p.D138H; 6:31356374-31356374	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.314delT; p.L105fs*46; 6:31356717-31356717	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Deletion - Frameshift
c.448_449insC; p.L150fs*27; 6:31356337-31356338	large_intestine; colon	carcinoma; adenocarcinoma	Insertion - Frameshift
c.19C>G; p.R7G; 6:31357140-31357140	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.206A>G; p.E69G; 6:31356825-31356825	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.506G>T; p.R169L; 6:31356280-31356280	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.19C>G; p.R7G; 6:31357140-31357140	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.506G>T; p.R169L; 6:31356280-31356280	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.165C>G; p.T55T; 6:31356866-31356866	thyroid	other; neoplasm	Substitution - coding silent
c.180C>T; p.F60F; 6:31356851-31356851	kidney	carcinoma; papillary_renal_cell_carcinoma	Substitution - coding silent
c.180C>T; p.F60F; 6:31356851-31356851	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.705G>A; p.A235A; 6:31355507-31355507	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.74-4C>T; p.?; 6:31356961-31356961	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Unknown
c.705G>A; p.A235A; 6:31355507-31355507	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.74-8A>G; p.?; 6:31356965-31356965	thyroid	other; neoplasm	Unknown
c.74-8A>G; p.?; 6:31356965-31356965	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Unknown
c.689T>C; p.L230P; 6:31355523-31355523	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.672C>T; p.T224T; 6:31355540-31355540	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.721T>C; p.W241R; 6:31355491-31355491	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.704C>A; p.A235E; 6:31355508-31355508	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.698A>G; p.Y233C; 6:31355514-31355514	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.362G>C; p.S121T; 6:31356424-31356424	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.986C>A; p.A329D; 6:31355133-31355133	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.755C>T; p.T252I; 6:31355457-31355457	skin	malignant_melanoma	Substitution - Missense
c.971G>T; p.G324V; 6:31355148-31355148	thyroid	other; neoplasm	Substitution - Missense
c.971G>T; p.G324V; 6:31355148-31355148	thyroid	other; neoplasm	Substitution - Missense
c.538C>G; p.R180G; 6:31356248-31356248	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.538C>G; p.R180G; 6:31356248-31356248	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.538C>G; p.R180G; 6:31356248-31356248	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.538C>G; p.R180G; 6:31356248-31356248	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.538C>G; p.R180G; 6:31356248-31356248	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.371G>A; p.G124D; 6:31356415-31356415	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.922_923insA; p.I308fs*26; 6:31355196-31355197	large_intestine; colon	carcinoma; adenocarcinoma	Insertion - Frameshift
c.206_207insT; p.E69fs*30; 6:31356824-31356825	large_intestine; rectum	carcinoma; adenocarcinoma	Insertion - Frameshift
c.206_207insT; p.E69fs*30; 6:31356824-31356825	large_intestine; colon	carcinoma; adenocarcinoma	Insertion - Frameshift
c.206_207insT; p.E69fs*30; 6:31356824-31356825	breast	carcinoma	Insertion - Frameshift
c.387G>C; p.P129P; 6:31356399-31356399	thyroid	other; neoplasm	Substitution - coding silent
c.782G>C; p.G261A; 6:31355430-31355430	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.387G>C; p.P129P; 6:31356399-31356399	thyroid	other; neoplasm	Substitution - coding silent
c.387G>C; p.P129P; 6:31356399-31356399	thyroid	other; neoplasm	Substitution - coding silent
c.207_208insT; p.E70fs*1; 6:31356823-31356824	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Insertion - Frameshift
c.560A>C; p.E187A; 6:31356226-31356226	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.560A>C; p.E187A; 6:31356226-31356226	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.560A>C; p.E187A; 6:31356226-31356226	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.560A>C; p.E187A; 6:31356226-31356226	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.560A>C; p.E187A; 6:31356226-31356226	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.560A>C; p.E187A; 6:31356226-31356226	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.560A>C; p.E187A; 6:31356226-31356226	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.560A>C; p.E187A; 6:31356226-31356226	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.419A>T; p.Y140F; 6:31356367-31356367	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.605A>C; p.K202T; 6:31356181-31356181	pancreas	carcinoma; ductal_carcinoma	Substitution - Missense
c.605A>C; p.K202T; 6:31356181-31356181	thyroid	other; neoplasm	Substitution - Missense
c.419A>T; p.Y140F; 6:31356367-31356367	urinary_tract; bladder	carcinoma	Substitution - Missense
c.419A>T; p.Y140F; 6:31356367-31356367	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.605A>C; p.K202T; 6:31356181-31356181	pancreas	pancreatic_intraepithelial_neoplasia_(PanIN)	Substitution - Missense
c.419A>T; p.Y140F; 6:31356367-31356367	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.419A>T; p.Y140F; 6:31356367-31356367	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.419A>T; p.Y140F; 6:31356367-31356367	thyroid	other; neoplasm	Substitution - Missense
c.419A>T; p.Y140F; 6:31356367-31356367	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.605A>C; p.K202T; 6:31356181-31356181	thyroid	other; neoplasm	Substitution - Missense
c.419A>T; p.Y140F; 6:31356367-31356367	thyroid	other; neoplasm	Substitution - Missense
c.605A>C; p.K202T; 6:31356181-31356181	pancreas	pancreatic_intraepithelial_neoplasia_(PanIN)	Substitution - Missense
c.419A>T; p.Y140F; 6:31356367-31356367	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.419A>T; p.Y140F; 6:31356367-31356367	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.419A>T; p.Y140F; 6:31356367-31356367	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.985G>A; p.A329T; 6:31355134-31355134	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.985G>A; p.A329T; 6:31355134-31355134	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.985G>A; p.A329T; 6:31355134-31355134	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.985G>A; p.A329T; 6:31355134-31355134	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.106G>A; p.V36M; 6:31356925-31356925	urinary_tract; bladder	carcinoma	Substitution - Missense
c.269T>A; p.I90N; 6:31356762-31356762	thyroid	other; neoplasm	Substitution - Missense
c.106G>A; p.V36M; 6:31356925-31356925	thyroid	other; neoplasm	Substitution - Missense
c.106G>A; p.V36M; 6:31356925-31356925	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.106G>A; p.V36M; 6:31356925-31356925	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.299A>T; p.E100V; 6:31356732-31356732	thyroid	other; neoplasm	Substitution - Missense
c.106G>A; p.V36M; 6:31356925-31356925	thyroid	other; neoplasm	Substitution - Missense
c.560A>T; p.E187V; 6:31356226-31356226	thyroid	other; neoplasm	Substitution - Missense
c.560A>T; p.E187V; 6:31356226-31356226	thyroid	other; neoplasm	Substitution - Missense
c.560A>T; p.E187V; 6:31356226-31356226	thyroid	other; neoplasm	Substitution - Missense
c.560A>T; p.E187V; 6:31356226-31356226	pancreas	pancreatic_intraepithelial_neoplasia_(PanIN)	Substitution - Missense
c.560A>T; p.E187V; 6:31356226-31356226	pancreas	pancreatic_intraepithelial_neoplasia_(PanIN)	Substitution - Missense
c.572G>C; p.W191S; 6:31356214-31356214	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.572G>C; p.W191S; 6:31356214-31356214	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.572G>C; p.W191S; 6:31356214-31356214	liver	carcinoma; hepatocellular_carcinoma	Substitution - Missense
c.499A>T; p.T167S; 6:31356287-31356287	urinary_tract; bladder	carcinoma	Substitution - Missense
c.572G>C; p.W191S; 6:31356214-31356214	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.572G>C; p.W191S; 6:31356214-31356214	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.477C>G; p.A159A; 6:31356309-31356309	thyroid	other; neoplasm	Substitution - coding silent
c.477C>G; p.A159A; 6:31356309-31356309	thyroid	other; neoplasm	Substitution - coding silent
c.477C>G; p.A159A; 6:31356309-31356309	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.103T>G; p.S35A; 6:31356928-31356928	urinary_tract; bladder	carcinoma	Substitution - Missense
c.103T>G; p.S35A; 6:31356928-31356928	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.103T>G; p.S35A; 6:31356928-31356928	thyroid	other; neoplasm	Substitution - Missense
c.103T>G; p.S35A; 6:31356928-31356928	thyroid	other; neoplasm	Substitution - Missense
c.620-2A>C; p.?; 6:31355594-31355594	stomach	carcinoma; adenocarcinoma	Unknown
c.968T>C; p.I323T; 6:31355151-31355151	thyroid	other; neoplasm	Substitution - Missense
c.312C>A; p.N104K; 6:31356719-31356719	prostate	carcinoma; adenocarcinoma	Substitution - Missense
c.212C>T; p.P71L; 6:31356819-31356819	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.636C>T; p.H212H; 6:31355576-31355576	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.246G>A; p.E82E; 6:31356785-31356785	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.862G>T; p.E288*; 6:31355350-31355350	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Nonsense
c.710T>G; p.I237S; 6:31355502-31355502	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.583T>C; p.Y195H; 6:31356203-31356203	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.583T>C; p.Y195H; 6:31356203-31356203	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.583T>C; p.Y195H; 6:31356203-31356203	thyroid	other; neoplasm	Substitution - Missense
c.583T>C; p.Y195H; 6:31356203-31356203	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.583T>C; p.Y195H; 6:31356203-31356203	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.583T>C; p.Y195H; 6:31356203-31356203	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.859C>T; p.H287Y; 6:31355353-31355353	haematopoietic_and_lymphoid_tissue; central_nervous_system	lymphoid_neoplasm; primary_central_nervous_system_lymphoma	Substitution - Missense
c.343G>A; p.G115R; 6:31356688-31356688	urinary_tract; bladder	carcinoma	Substitution - Missense
c.648C>T; p.H216H; 6:31355564-31355564	liver	carcinoma	Substitution - coding silent
c.855A>G; p.V285V; 6:31355357-31355357	thyroid	other; neoplasm	Substitution - coding silent
c.855A>G; p.V285V; 6:31355357-31355357	thyroid	other; neoplasm	Substitution - coding silent
c.355C>A; p.L119I; 6:31356431-31356431	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.355C>A; p.L119I; 6:31356431-31356431	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.355C>A; p.L119I; 6:31356431-31356431	thyroid	other; neoplasm	Substitution - Missense
c.355C>A; p.L119I; 6:31356431-31356431	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.355C>A; p.L119I; 6:31356431-31356431	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.355C>A; p.L119I; 6:31356431-31356431	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.355C>A; p.L119I; 6:31356431-31356431	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.409C>T; p.H137Y; 6:31356377-31356377	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.714_715delAC; p.L239fs*14; 6:31355497-31355498	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; NK-T_cell_lymphoma	Deletion - Frameshift
c.409C>T; p.H137Y; 6:31356377-31356377	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.409C>T; p.H137Y; 6:31356377-31356377	liver	carcinoma; hepatocellular_carcinoma	Substitution - Missense
c.311A>T; p.N104I; 6:31356720-31356720	thyroid	other; neoplasm	Substitution - Missense
c.539G>A; p.R180Q; 6:31356247-31356247	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.681C>A; p.C227*; 6:31355531-31355531	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Nonsense
c.539G>A; p.R180Q; 6:31356247-31356247	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.539G>A; p.R180Q; 6:31356247-31356247	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.681C>A; p.C227*; 6:31355531-31355531	stomach	carcinoma; adenocarcinoma	Substitution - Nonsense
c.409C>T; p.H137Y; 6:31356377-31356377	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.409C>T; p.H137Y; 6:31356377-31356377	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.539G>A; p.R180Q; 6:31356247-31356247	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.409C>T; p.H137Y; 6:31356377-31356377	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.409C>T; p.H137Y; 6:31356377-31356377	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.311A>T; p.N104I; 6:31356720-31356720	thyroid	other; neoplasm	Substitution - Missense
c.539G>A; p.R180Q; 6:31356247-31356247	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.409C>T; p.H137Y; 6:31356377-31356377	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.409C>T; p.H137Y; 6:31356377-31356377	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.409C>T; p.H137Y; 6:31356377-31356377	biliary_tract; gallbladder	carcinoma; adenocarcinoma	Substitution - Missense
c.409C>T; p.H137Y; 6:31356377-31356377	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.409C>T; p.H137Y; 6:31356377-31356377	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.539G>A; p.R180Q; 6:31356247-31356247	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.409C>T; p.H137Y; 6:31356377-31356377	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1044G>A; p.A348A; 6:31354634-31354634	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - coding silent
c.1044G>A; p.A348A; 6:31354634-31354634	pancreas	carcinoma	Substitution - coding silent
c.353C>T; p.T118I; 6:31356433-31356433	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.353C>T; p.T118I; 6:31356433-31356433	thyroid	other; neoplasm	Substitution - Missense
c.353C>T; p.T118I; 6:31356433-31356433	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.353C>T; p.T118I; 6:31356433-31356433	thyroid	other; neoplasm	Substitution - Missense
c.353C>T; p.T118I; 6:31356433-31356433	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.353C>T; p.T118I; 6:31356433-31356433	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.926_927delTG; p.V309fs*24; 6:31355192-31355193	upper_aerodigestive_tract; mouth	carcinoma; squamous_cell_carcinoma	Deletion - Frameshift
c.353C>T; p.T118I; 6:31356433-31356433	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.419A>C; p.Y140S; 6:31356367-31356367	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.353C>T; p.T118I; 6:31356433-31356433	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.767A>T; p.E256V; 6:31355445-31355445	stomach	carcinoma; intestinal_adenocarcinoma	Substitution - Missense
c.344-1G>C; p.?; 6:31356443-31356443	large_intestine; colon	carcinoma; adenocarcinoma	Unknown
c.724C>T; p.Q242*; 6:31355488-31355488	stomach	carcinoma; adenocarcinoma	Substitution - Nonsense
c.207_208insC; p.E70fs*29; 6:31356823-31356824	upper_aerodigestive_tract; mouth	carcinoma; squamous_cell_carcinoma	Insertion - Frameshift
c.709A>T; p.I237F; 6:31355503-31355503	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.141C>T; p.I47I; 6:31356890-31356890	urinary_tract; bladder	carcinoma	Substitution - coding silent
c.141C>T; p.I47I; 6:31356890-31356890	urinary_tract; bladder	carcinoma	Substitution - coding silent
c.141C>T; p.I47I; 6:31356890-31356890	urinary_tract; bladder	carcinoma	Substitution - coding silent
c.720delC; p.W241fs*56; 6:31355492-31355492	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.317G>T; p.R106L; 6:31356714-31356714	thyroid	other; neoplasm	Substitution - Missense
c.317G>T; p.R106L; 6:31356714-31356714	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.317G>T; p.R106L; 6:31356714-31356714	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.317G>T; p.R106L; 6:31356714-31356714	thyroid	other; neoplasm	Substitution - Missense
c.317G>T; p.R106L; 6:31356714-31356714	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.787A>G; p.R263G; 6:31355425-31355425	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.787A>G; p.R263G; 6:31355425-31355425	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.787A>G; p.R263G; 6:31355425-31355425	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.787A>G; p.R263G; 6:31355425-31355425	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.787A>G; p.R263G; 6:31355425-31355425	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.272A>G; p.Y91C; 6:31356759-31356759	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.787A>G; p.R263G; 6:31355425-31355425	thyroid	other; neoplasm	Substitution - Missense
c.787A>G; p.R263G; 6:31355425-31355425	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.787A>G; p.R263G; 6:31355425-31355425	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.272A>G; p.Y91C; 6:31356759-31356759	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.204delA; p.E69fs*8; 6:31356827-31356827	large_intestine; rectum	carcinoma; adenocarcinoma	Deletion - Frameshift
c.204delA; p.E69fs*8; 6:31356827-31356827	large_intestine; rectum	carcinoma; adenocarcinoma	Deletion - Frameshift
c.626_627insC; p.T211fs*10; 6:31355585-31355586	oesophagus	carcinoma; adenocarcinoma	Insertion - Frameshift
c.1012+1G>A; p.?; 6:31355106-31355106	stomach	carcinoma; adenocarcinoma	Unknown
c.626_627insC; p.T211fs*10; 6:31355585-31355586	oesophagus	carcinoma; adenocarcinoma	Insertion - Frameshift
c.204delA; p.E69fs*8; 6:31356827-31356827	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.1012+1G>A; p.?; 6:31355106-31355106	large_intestine; colon	carcinoma; adenocarcinoma	Unknown
c.626_627insC; p.T211fs*10; 6:31355585-31355586	large_intestine; colon	carcinoma; adenocarcinoma	Insertion - Frameshift
c.204delA; p.E69fs*8; 6:31356827-31356827	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Deletion - Frameshift
c.204delA; p.E69fs*8; 6:31356827-31356827	upper_aerodigestive_tract; mouth	carcinoma; squamous_cell_carcinoma	Deletion - Frameshift
c.313C>G; p.L105V; 6:31356718-31356718	thyroid	other; neoplasm	Substitution - Missense
c.313C>G; p.L105V; 6:31356718-31356718	urinary_tract; bladder	carcinoma	Substitution - Missense
c.559G>A; p.E187K; 6:31356227-31356227	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.924C>T; p.I308I; 6:31355195-31355195	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.559G>A; p.E187K; 6:31356227-31356227	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.538C>T; p.R180W; 6:31356248-31356248	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.538C>T; p.R180W; 6:31356248-31356248	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.559G>A; p.E187K; 6:31356227-31356227	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.538C>T; p.R180W; 6:31356248-31356248	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.133_134insC; p.R45fs*54; 6:31356897-31356898	large_intestine; colon	carcinoma; adenocarcinoma	Insertion - Frameshift
c.538C>T; p.R180W; 6:31356248-31356248	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.313C>G; p.L105V; 6:31356718-31356718	thyroid	other; neoplasm	Substitution - Missense
c.559G>A; p.E187K; 6:31356227-31356227	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.559G>A; p.E187K; 6:31356227-31356227	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.538C>T; p.R180W; 6:31356248-31356248	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.559G>A; p.E187K; 6:31356227-31356227	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.538C>T; p.R180W; 6:31356248-31356248	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.44delC; p.A15fs*5; 6:31357115-31357115	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.559G>A; p.E187K; 6:31356227-31356227	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.538C>T; p.R180W; 6:31356248-31356248	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.538C>T; p.R180W; 6:31356248-31356248	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.559G>A; p.E187K; 6:31356227-31356227	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.620-1G>C; p.?; 6:31355593-31355593	lung	carcinoma; adenocarcinoma	Unknown
c.142T>G; p.S48A; 6:31356889-31356889	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.142T>G; p.S48A; 6:31356889-31356889	thyroid	other; neoplasm	Substitution - Missense
c.292G>T; p.D98Y; 6:31356739-31356739	thyroid	other; neoplasm	Substitution - Missense
c.512G>T; p.W171L; 6:31356274-31356274	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.226A>G; p.I76V; 6:31356805-31356805	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.80A>C; p.H27P; 6:31356951-31356951	urinary_tract; bladder	carcinoma	Substitution - Missense
c.226A>G; p.I76V; 6:31356805-31356805	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.292G>T; p.D98Y; 6:31356739-31356739	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.226A>G; p.I76V; 6:31356805-31356805	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.379G>C; p.V127L; 6:31356407-31356407	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.379G>C; p.V127L; 6:31356407-31356407	thyroid	other; neoplasm	Substitution - Missense
c.379G>C; p.V127L; 6:31356407-31356407	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.379G>C; p.V127L; 6:31356407-31356407	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.626delC; p.P209fs*5; 6:31355586-31355586	large_intestine; caecum	carcinoma; adenocarcinoma	Deletion - Frameshift
c.626delC; p.P209fs*5; 6:31355586-31355586	stomach	carcinoma; intestinal_adenocarcinoma	Deletion - Frameshift
c.412G>A; p.D138N; 6:31356374-31356374	urinary_tract; bladder	carcinoma	Substitution - Missense
c.412G>A; p.D138N; 6:31356374-31356374	thyroid	other; neoplasm	Substitution - Missense
c.142T>A; p.S48T; 6:31356889-31356889	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.142T>A; p.S48T; 6:31356889-31356889	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.142T>A; p.S48T; 6:31356889-31356889	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.209A>C; p.E70A; 6:31356822-31356822	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.209A>C; p.E70A; 6:31356822-31356822	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.209A>C; p.E70A; 6:31356822-31356822	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.435G>A; p.K145K; 6:31356351-31356351	thyroid	other; neoplasm	Substitution - coding silent
c.334A>C; p.S112R; 6:31356697-31356697	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.470G>A; p.W157*; 6:31356316-31356316	urinary_tract; bladder	carcinoma; transitional_cell_carcinoma	Substitution - Nonsense
c.470G>A; p.W157*; 6:31356316-31356316	urinary_tract; bladder	carcinoma	Substitution - Nonsense
c.917delT; p.V306fs*13; 6:31355202-31355202	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.895G>A; p.E299K; 6:31355317-31355317	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.895G>A; p.E299K; 6:31355317-31355317	thyroid	other; neoplasm	Substitution - Missense
c.895G>A; p.E299K; 6:31355317-31355317	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.302G>A; p.S101N; 6:31356729-31356729	thyroid	other; neoplasm	Substitution - Missense
c.282G>C; p.Q94H; 6:31356749-31356749	thyroid	other; neoplasm	Substitution - Missense
c.270C>T; p.I90I; 6:31356761-31356761	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.74-9C>T; p.?; 6:31356966-31356966	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Unknown
c.74-9C>T; p.?; 6:31356966-31356966	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Unknown
c.282G>C; p.Q94H; 6:31356749-31356749	thyroid	other; neoplasm	Substitution - Missense
c.74-9C>T; p.?; 6:31356966-31356966	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Unknown
c.74-9C>T; p.?; 6:31356966-31356966	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Unknown
c.282G>C; p.Q94H; 6:31356749-31356749	thyroid	other; neoplasm	Substitution - Missense
c.222G>A; p.P74P; 6:31356809-31356809	urinary_tract; bladder	carcinoma	Substitution - coding silent
c.45G>A; p.A15A; 6:31357114-31357114	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.25G>C; p.V9L; 6:31357134-31357134	central_nervous_system; cerebellum	glioma; ependymoma	Substitution - Missense
c.1016G>C; p.G339A; 6:31354662-31354662	skin	malignant_melanoma	Substitution - Missense
c.723G>A; p.W241*; 6:31355489-31355489	stomach	carcinoma; adenocarcinoma	Substitution - Nonsense
c.956C>A; p.A319E; 6:31355163-31355163	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.786T>C; p.D262D; 6:31355426-31355426	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.314T>C; p.L105P; 6:31356717-31356717	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.314T>C; p.L105P; 6:31356717-31356717	thyroid	other; neoplasm	Substitution - Missense
c.314T>C; p.L105P; 6:31356717-31356717	urinary_tract; bladder	carcinoma	Substitution - Missense
c.229G>C; p.E77Q; 6:31356802-31356802	urinary_tract; bladder	carcinoma	Substitution - Missense
c.314T>C; p.L105P; 6:31356717-31356717	pancreas	carcinoma	Substitution - Missense
c.314T>C; p.L105P; 6:31356717-31356717	thyroid	other; neoplasm	Substitution - Missense
c.314T>C; p.L105P; 6:31356717-31356717	urinary_tract; bladder	carcinoma	Substitution - Missense
c.314T>C; p.L105P; 6:31356717-31356717	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.357C>G; p.L119L; 6:31356429-31356429	thyroid	other; neoplasm	Substitution - coding silent
c.895+2T>C; p.?; 6:31355315-31355315	stomach	carcinoma; adenocarcinoma	Unknown
c.357C>G; p.L119L; 6:31356429-31356429	thyroid	other; neoplasm	Substitution - coding silent
c.285A>G; p.A95A; 6:31356746-31356746	thyroid	other; neoplasm	Substitution - coding silent

Annotation category 5

Basic annotation

Literature evidence

Expression

Somatic mutation

Network

ceRNA

Gene information

COSMIC somatic mutation