Cancer metastasis database

Annotation category 5

Gene information

Gene ID 29968
Symbol

PSAT1

Synonymous

EPIP|NLS2|PSA|PSAT|PSATD

Full name

phosphoserine aminotransferase 1

Gene description

endometrial progesterone-induced protein|phosphohydroxythreonine aminotransferase|phosphoserine aminotransferase

Cytoband

9q21.2

Gene type

protein-coding

Synonymous

MIM:610936; HGNC:HGNC:19129; Ensembl:ENSG00000135069; HPRD:17918; Vega:OTTHUMG00000020066

COSMIC somatic mutation

Mutation (CDS; AA; Chr)

Site

Histology

Mutation Type

c.7_8insC; p.R5fs*34; 9:78297217-78297218

 large_intestine; coloncarcinoma; adenocarcinomaInsertion - Frameshift

c.253G>C; p.A85P; 9:78304796-78304796

 lungcarcinoma; small_cell_carcinomaSubstitution - Missense

c.253G>C; p.A85P; 9:78304796-78304796

 lungcarcinoma; small_cell_carcinomaSubstitution - Missense

c.239G>A; p.C80Y; 9:78304782-78304782

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.665G>A; p.R222Q; 9:78308508-78308508

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.646C>T; p.L216L; 9:78308489-78308489

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.239G>A; p.C80Y; 9:78304782-78304782

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.381A>G; p.K127K; 9:78304924-78304924

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.369C>T; p.I123I; 9:78304912-78304912

 skinmalignant_melanomaSubstitution - coding silent

c.369C>T; p.I123I; 9:78304912-78304912

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.543C>T; p.F181F; 9:78306459-78306459

 skinmalignant_melanomaSubstitution - coding silent

c.321G>T; p.W107C; 9:78304864-78304864

 breastcarcinomaSubstitution - Missense

c.519G>A; p.L173L; 9:78306435-78306435

 skinmalignant_melanomaSubstitution - coding silent

c.254C>T; p.A85V; 9:78304797-78304797

 skinmalignant_melanomaSubstitution - Missense

c.279G>T; p.L93F; 9:78304822-78304822

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.934G>A; p.G312R; 9:78328115-78328115

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.217_218insT; p.L75fs*26; 9:78304760-78304761

 large_intestine; caecumcarcinoma; adenocarcinomaInsertion - Frameshift

c.455G>A; p.C152Y; 9:78306371-78306371

 prostatecarcinoma; adenocarcinomaSubstitution - Missense

c.74T>C; p.I25T; 9:78300615-78300615

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.257T>A; p.V86D; 9:78304800-78304800

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.487G>A; p.D163N; 9:78306403-78306403

 central_nervous_system; brainglioma; astrocytoma_Grade_IVSubstitution - Missense

c.183G>A; p.R61R; 9:78302015-78302015

 skinmalignant_melanomaSubstitution - coding silent

c.241G>A; p.G81S; 9:78304784-78304784

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.401T>C; p.I134T; 9:78306317-78306317

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.328A>C; p.K110Q; 9:78304871-78304871

 thyroidcarcinomaSubstitution - Missense

c.181C>T; p.R61W; 9:78302013-78302013

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.511G>A; p.A171T; 9:78306427-78306427

 central_nervous_system; brainglioma; astrocytoma_Grade_IVSubstitution - Missense

c.346A>G; p.K116E; 9:78304889-78304889

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.323C>T; p.S108L; 9:78304866-78304866

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.607G>A; p.G203S; 9:78308450-78308450

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.973C>T; p.L325F; 9:78328154-78328154

 skinmalignant_melanomaSubstitution - Missense

c.171G>T; p.E57D; 9:78302003-78302003

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.171G>T; p.E57D; 9:78302003-78302003

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - Missense

c.373C>T; p.H125Y; 9:78304916-78304916

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.397+2T>C; p.?; 9:78304942-78304942

 kidneycarcinoma; clear_cell_renal_cell_carcinomaUnknown

c.508G>T; p.G170*; 9:78306424-78306424

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Nonsense

c.848A>T; p.D283V; 9:78317783-78317783

 oesophagus; middle_thirdcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.910C>T; p.P304S; 9:78328091-78328091

 skinmalignant_melanomaSubstitution - Missense

c.741C>T; p.S247S; 9:78317676-78317676

 livercarcinomaSubstitution - coding silent

c.917G>A; p.R306H; 9:78328098-78328098

 breastcarcinomaSubstitution - Missense

c.499G>A; p.D167N; 9:78306415-78306415

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.747C>T; p.Y249Y; 9:78317682-78317682

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.873T>C; p.C291C; 9:78328054-78328054

 stomachcarcinoma; adenocarcinomaSubstitution - coding silent

c.280A>G; p.K94E; 9:78304823-78304823

 livercarcinomaSubstitution - Missense

c.1059C>T; p.D353D; 9:78329032-78329032

 haematopoietic_and_lymphoid_tissuehaematopoietic_neoplasm; acute_myeloid_leukaemiaSubstitution - coding silent

c.286G>A; p.G96R; 9:78304829-78304829

 skinmalignant_melanomaSubstitution - Missense

c.682C>T; p.L228L; 9:78308525-78308525

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.1015G>T; p.G339*; 9:78328988-78328988

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Nonsense

c.297T>G; p.A99A; 9:78304840-78304840

 thyroidother; neoplasmSubstitution - coding silent

c.578T>C; p.V193A; 9:78308421-78308421

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.877G>A; p.V293M; 9:78328058-78328058

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.950_951insA; p.R319fs*4; 9:78328131-78328132

 stomachcarcinoma; intestinal_adenocarcinomaInsertion - Frameshift

c.661C>T; p.L221F; 9:78308504-78308504

 skinmalignant_melanomaSubstitution - Missense

c.178G>T; p.V60L; 9:78302010-78302010

 lung; right_upper_lobecarcinoma; adenocarcinomaSubstitution - Missense

c.128G>A; p.S43N; 9:78301960-78301960

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.850A>T; p.N284Y; 9:78317785-78317785

 lungcarcinoma; small_cell_carcinomaSubstitution - Missense

c.307G>A; p.V103M; 9:78304850-78304850

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.961C>A; p.L321I; 9:78328142-78328142

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.636C>T; p.V212V; 9:78308479-78308479

 skinmalignant_melanomaSubstitution - coding silent

c.988T>C; p.L330L; 9:78328169-78328169

 lung; right_lower_lobecarcinoma; adenocarcinomaSubstitution - coding silent

c.999_1005delAGGGCAT; p.H335fs*25; 9:78328180-78328186

 ovarycarcinoma; serous_carcinomaDeletion - Frameshift

c.59C>G; p.S20*; 9:78297269-78297269

 urinary_tract; bladdercarcinomaSubstitution - Nonsense

c.1089A>T; p.K363N; 9:78329062-78329062

 stomachcarcinoma; adenocarcinomaSubstitution - Missense