Cancer metastasis database

Annotation category 5

Gene information

Gene ID 2941
Symbol

GSTA4

Synonymous

GSTA4-4|GTA4

Full name

glutathione S-transferase alpha 4

Gene description

GST class-alpha member 4|S-(hydroxyalkyl)glutathione lyase A4|glutathione S-alkyltransferase A4|glutathione S-aralkyltransferase A4|glutathione S-aryltransferase A4|glutathione S-transferase A4|glutathione S-transferase A4-4|glutathione transferase A4-4

Cytoband

6p12.1

Gene type

protein-coding

Synonymous

MIM:605450; HGNC:HGNC:4629; Ensembl:ENSG00000170899; HPRD:06899; Vega:OTTHUMG00000014868

COSMIC somatic mutation

Mutation (CDS; AA; Chr)

Site

Histology

Mutation Type

c.97G>T; p.E33*; 6:52987399-52987399

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Nonsense

c.191A>C; p.K64T; 6:52985532-52985532

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.197T>C; p.V66A; 6:52985526-52985526

 skin; upper_legmalignant_melanomaSubstitution - Missense

c.357G>T; p.K119N; 6:52984521-52984521

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.386T>G; p.I129R; 6:52984492-52984492

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - Missense

c.323T>A; p.M108K; 6:52984555-52984555

 eye; uveal_tractmalignant_melanoma; mixedSubstitution - Missense

c.310G>A; p.E104K; 6:52984568-52984568

 urinary_tract; bladdercarcinoma; transitional_cell_carcinomaSubstitution - Missense

c.175G>A; p.E59K; 6:52985548-52985548

 urinary_tract; bladdercarcinomaSubstitution - Missense

c.310G>A; p.E104K; 6:52984568-52984568

 urinary_tract; bladdercarcinomaSubstitution - Missense

c.430G>T; p.G144*; 6:52982690-52982690

 haematopoietic_and_lymphoid_tissuelymphoid_neoplasm; hairy_cell_leukaemiaSubstitution - Nonsense

c.283T>C; p.Y95H; 6:52984595-52984595

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.602G>T; p.G201V; 6:52978537-52978537

 ovarycarcinoma; serous_carcinomaSubstitution - Missense

c.136G>A; p.D46N; 6:52987360-52987360

 livercarcinoma; hepatocellular_carcinomaSubstitution - Missense

c.240T>C; p.N80N; 6:52985483-52985483

 bone; tibiaEwings_sarcoma-peripheral_primitive_neuroectodermal_tumourSubstitution - coding silent

c.589T>C; p.F197L; 6:52978550-52978550

 skin; scalpcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.535C>T; p.P179S; 6:52982585-52982585

 skin; scalpcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.430G>A; p.G144R; 6:52982690-52982690

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.623delC; p.P208fs*6; 6:52978516-52978516

 large_intestine; coloncarcinoma; adenocarcinomaDeletion - Frameshift

c.136G>T; p.D46Y; 6:52987360-52987360

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.98A>G; p.E33G; 6:52987398-52987398

 salivary_gland; parotidcarcinoma; adenoid_cystic_carcinomaSubstitution - Missense

c.145C>T; p.H49Y; 6:52985578-52985578

 central_nervous_system; brainglioma; astrocytoma_Grade_IVSubstitution - Missense

c.252G>T; p.K84N; 6:52985471-52985471

 lung; right_upper_lobecarcinoma; adenocarcinomaSubstitution - Missense

c.507G>T; p.E169D; 6:52982613-52982613

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.176A>G; p.E59G; 6:52985547-52985547

 biliary_tract; gallbladdercarcinoma; adenocarcinomaSubstitution - Missense

c.523C>A; p.L175M; 6:52982597-52982597

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.523C>A; p.L175M; 6:52982597-52982597

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.352C>T; p.Q118*; 6:52984526-52984526

 breastcarcinomaSubstitution - Nonsense

c.177A>C; p.E59D; 6:52985546-52985546

 central_nervous_system; brainglioma; astrocytoma_Grade_IVSubstitution - Missense

c.177A>C; p.E59D; 6:52985546-52985546

 central_nervous_system; brainglioma; astrocytoma_Grade_IVSubstitution - Missense

c.291G>T; p.E97D; 6:52984587-52984587

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.285C>T; p.Y95Y; 6:52984593-52984593

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - coding silent

c.553A>G; p.T185A; 6:52978586-52978586

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.293G>A; p.G98E; 6:52984585-52984585

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.601G>T; p.G201C; 6:52978538-52978538

 autonomic_ganglianeuroblastomaSubstitution - Missense

c.415-1G>A; p.?; 6:52982706-52982706

 skinmalignant_melanomaUnknown

c.368A>C; p.N123T; 6:52984510-52984510

 upper_aerodigestive_tract; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.646G>A; p.V216I; 6:52978493-52978493

 livercarcinomaSubstitution - Missense

c.646G>A; p.V216I; 6:52978493-52978493

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.646G>A; p.V216I; 6:52978493-52978493

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense