lung cancer gene and literature database Home

Annotation category 5

Basic annotation
Ontology and pathways
Literature evidence
Curated literatures
Expression
Gene expression chart
Somatic mutation
COSMIC and TCGA mutations
Network
Gene interaction
ceRNA
Gene-related ceRNA

Gene information

Gene ID	2939
Symbol	GSTA2
Synonymous	GST2\|GSTA2-2\|GTA2\|GTH2
Full name	glutathione S-transferase alpha 2
Gene description	GST HA subunit 2\|GST class-alpha member 2\|GST-gamma\|S-(hydroxyalkyl)glutathione lyase A2\|glutathione S-alkyltransferase A2\|glutathione S-aralkyltransferase A2\|glutathione S-aryltransferase A2\|glutathione S-transferase A2\|liver GST2
Cytoband	6p12.1
Gene type	protein-coding
Synonymous	MIM:138360; HGNC:HGNC:4627; Ensembl:ENSG00000244067; HPRD:00709; Vega:OTTHUMG00000016263

COSMIC somatic mutation

Mutation (CDS; AA; Chr)	Site	Histology	Mutation Type
c.318C>T; p.I106I; 6:52752950-52752950	upper_aerodigestive_tract; mouth	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.318C>T; p.I106I; 6:52752950-52752950	upper_aerodigestive_tract; mouth	carcinoma	Substitution - coding silent
c.431G>A; p.G144E; 6:52751692-52751692	thyroid	carcinoma	Substitution - Missense
c.66C>T; p.L22L; 6:52757882-52757882	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.67C>T; p.L23L; 6:52757881-52757881	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - coding silent
c.477C>A; p.H159Q; 6:52751646-52751646	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.181G>C; p.D61H; 6:52755034-52755034	breast	carcinoma; basal_(triple-negative)_carcinoma	Substitution - Missense
c.289G>A; p.E97K; 6:52752979-52752979	skin; neck	malignant_melanoma	Substitution - Missense
c.399C>T; p.F133F; 6:52752869-52752869	skin	malignant_melanoma	Substitution - coding silent
c.351A>T; p.Q117H; 6:52752917-52752917	kidney	carcinoma; papillary_renal_cell_carcinoma	Substitution - Missense
c.103A>T; p.I35L; 6:52756294-52756294	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.103A>T; p.I35L; 6:52756294-52756294	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.378G>T; p.E126D; 6:52752890-52752890	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.378G>T; p.E126D; 6:52752890-52752890	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.167delC; p.P56fs*8; 6:52755048-52755048	skin	malignant_melanoma	Deletion - Frameshift
c.629A>C; p.E210A; 6:52750617-52750617	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.96G>T; p.E32D; 6:52756301-52756301	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.591T>G; p.F197L; 6:52750655-52750655	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.29C>G; p.S10C; 6:52757919-52757919	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.446T>C; p.V149A; 6:52751677-52751677	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.430G>A; p.G144R; 6:52751693-52751693	skin; trunk	malignant_melanoma	Substitution - Missense
c.341C>T; p.P114L; 6:52752927-52752927	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.430G>A; p.G144R; 6:52751693-52751693	skin; trunk	malignant_melanoma	Substitution - Missense
c.299C>T; p.A100V; 6:52752969-52752969	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.124G>A; p.D42N; 6:52756273-52756273	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.220T>A; p.Y74N; 6:52754995-52754995	urinary_tract; bladder	carcinoma	Substitution - Missense
c.220T>A; p.Y74N; 6:52754995-52754995	urinary_tract; bladder	carcinoma; transitional_cell_carcinoma	Substitution - Missense
c.585G>C; p.K195N; 6:52750661-52750661	urinary_tract; bladder	carcinoma	Substitution - Missense
c.391C>T; p.R131C; 6:52752877-52752877	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.585G>A; p.K195K; 6:52750661-52750661	skin	malignant_melanoma	Substitution - coding silent
c.96G>A; p.E32E; 6:52756301-52756301	upper_aerodigestive_tract; pharynx	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.55A>T; p.I19F; 6:52757893-52757893	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.527C>A; p.S176Y; 6:52751596-52751596	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.663G>T; p.R221S; 6:52750583-52750583	urinary_tract; bladder	carcinoma	Substitution - Missense
c.554A>G; p.K185R; 6:52750692-52750692	skin	malignant_melanoma	Substitution - Missense
c.13C>G; p.P5A; 6:52757935-52757935	bone; extraskeletal	Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	Substitution - Missense
c.538C>G; p.L180V; 6:52751585-52751585	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.4G>A; p.A2T; 6:52757944-52757944	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.594A>G; p.L198L; 6:52750652-52750652	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.498C>T; p.Y166Y; 6:52751625-52751625	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - coding silent
c.651G>A; p.R217R; 6:52750595-52750595	skin	malignant_melanoma	Substitution - coding silent
c.243C>T; p.L81L; 6:52754972-52754972	skin	malignant_melanoma	Substitution - coding silent
c.666T>G; p.F222L; 6:52750580-52750580	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.536C>T; p.P179L; 6:52751587-52751587	skin	malignant_melanoma	Substitution - Missense
c.177G>A; p.E59E; 6:52755038-52755038	oesophagus; lower_third	carcinoma; adenocarcinoma	Substitution - coding silent
c.618T>C; p.P206P; 6:52750628-52750628	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - coding silent
c.487C>T; p.L163F; 6:52751636-52751636	breast	carcinoma	Substitution - Missense
c.455A>T; p.K152M; 6:52751668-52751668	prostate	carcinoma; adenocarcinoma	Substitution - Missense
c.335G>C; p.S112T; 6:52752933-52752933	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.319C>T; p.L107F; 6:52752949-52752949	skin	malignant_melanoma	Substitution - Missense
c.617C>A; p.P206H; 6:52750629-52750629	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.173T>C; p.V58A; 6:52755042-52755042	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.587A>C; p.K196T; 6:52750659-52750659	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.328C>T; p.P110S; 6:52752940-52752940	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.328C>T; p.P110S; 6:52752940-52752940	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.635C>T; p.S212F; 6:52750611-52750611	skin; mucosal	malignant_melanoma	Substitution - Missense
c.422A>G; p.K141R; 6:52751701-52751701	skin	malignant_melanoma	Substitution - Missense

Annotation category 5

Basic annotation

Literature evidence

Expression

Somatic mutation

Network

ceRNA

Gene information

COSMIC somatic mutation