Cancer metastasis database

Annotation category 5

Gene information

Gene ID 2938
Symbol

GSTA1

Synonymous

GST2|GSTA1-1|GTH1

Full name

glutathione S-transferase alpha 1

Gene description

GST HA subunit 1|GST class-alpha member 1|GST, class alpha, 1|GST-epsilon|S-(hydroxyalkyl)glutathione lyase A1|glutathione S-alkyltransferase A1|glutathione S-aryltransferase A1|glutathione S-transferase 2|glutathione S-transferase A1|glutathione S-transf

Cytoband

6p12.1

Gene type

protein-coding

Synonymous

MIM:138359; HGNC:HGNC:4626; HPRD:00708

COSMIC somatic mutation

Mutation (CDS; AA; Chr)

Site

Histology

Mutation Type

c.436G>A; p.D146N; 6:52792966-52792966

 skinmalignant_melanomaSubstitution - Missense

c.330C>T; p.P110P; 6:52794209-52794209

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.135A>T; p.R45S; 6:52797590-52797590

 livercarcinoma; hepatocellular_carcinomaSubstitution - Missense

c.234A>G; p.K78K; 6:52796220-52796220

 lungcarcinoma; adenocarcinomaSubstitution - coding silent

c.506A>G; p.E169G; 6:52792896-52792896

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.355G>A; p.A119T; 6:52794184-52794184

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.500T>G; p.V167G; 6:52792902-52792902

 lung; right_upper_lobecarcinoma; adenocarcinomaSubstitution - Missense

c.660C>G; p.F220L; 6:52791867-52791867

 upper_aerodigestive_tract; mouthcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.654G>A; p.K218K; 6:52791873-52791873

 skinmalignant_melanomaSubstitution - coding silent

c.237C>A; p.Y79*; 6:52796217-52796217

 autonomic_ganglianeuroblastomaSubstitution - Nonsense

c.395A>G; p.Y132C; 6:52794144-52794144

 livercarcinomaSubstitution - Missense

c.531C>A; p.S177R; 6:52792871-52792871

 autonomic_ganglianeuroblastomaSubstitution - Missense

c.252A>T; p.K84N; 6:52796202-52796202

 pancreascarcinomaSubstitution - Missense

c.425G>T; p.S142I; 6:52792977-52792977

 livercarcinoma; hepatocellular_carcinomaSubstitution - Missense

c.515C>G; p.S172C; 6:52792887-52792887

 lungcarcinoma; bronchioloalveolar_adenocarcinomaSubstitution - Missense

c.319C>G; p.L107V; 6:52794220-52794220

 urinary_tract; bladdercarcinomaSubstitution - Missense

c.181G>A; p.D61N; 6:52796273-52796273

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.498C>G; p.Y166*; 6:52792904-52792904

 lung; right_upper_lobecarcinoma; adenocarcinomaSubstitution - Nonsense

c.325C>T; p.L109L; 6:52794214-52794214

 lung; right_upper_lobecarcinoma; adenocarcinomaSubstitution - coding silent

c.325C>T; p.L109L; 6:52794214-52794214

 lungcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.404C>T; p.A135V; 6:52794135-52794135

 livercarcinomaSubstitution - Missense

c.391C>T; p.R131C; 6:52794148-52794148

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.391C>T; p.R131C; 6:52794148-52794148

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.266G>A; p.R89K; 6:52796188-52796188

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.157C>A; p.Q53K; 6:52796297-52796297

 haematopoietic_and_lymphoid_tissuelymphoid_neoplasm; chronic_lymphocytic_leukaemia-small_lymphocytic_lymphomaSubstitution - Missense

c.15C>T; p.P5P; 6:52799253-52799253

 haematopoietic_and_lymphoid_tissuehaematopoietic_neoplasm; acute_myeloid_leukaemiaSubstitution - coding silent

c.15C>T; p.P5P; 6:52799253-52799253

 haematopoietic_and_lymphoid_tissuehaematopoietic_neoplasm; acute_myeloid_leukaemiaSubstitution - coding silent

c.490C>A; p.L164I; 6:52792912-52792912

 lungcarcinoma; small_cell_carcinomaSubstitution - Missense

c.43A>G; p.R15G; 6:52799225-52799225

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.331G>A; p.V111I; 6:52794208-52794208

 central_nervous_system; brainglioma; astrocytoma_Grade_IVSubstitution - Missense

c.227C>T; p.A76V; 6:52796227-52796227

 breastcarcinomaSubstitution - Missense

c.30C>G; p.F10L; 6:52799238-52799238

 breastcarcinomaSubstitution - Missense

c.643G>A; p.E215K; 6:52791884-52791884

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - Missense

c.349A>C; p.K117Q; 6:52794190-52794190

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.643G>A; p.E215K; 6:52791884-52791884

 skinmalignant_melanomaSubstitution - Missense

c.650G>A; p.R217K; 6:52791877-52791877

 skinmalignant_melanomaSubstitution - Missense

c.470A>T; p.D157V; 6:52792932-52792932

 livercarcinoma; hepatocellular_carcinomaSubstitution - Missense

c.463C>A; p.R155R; 6:52792939-52792939

 stomachcarcinoma; adenocarcinomaSubstitution - coding silent

c.381A>C; p.K127N; 6:52794158-52794158

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.630G>T; p.E210D; 6:52791897-52791897

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Missense

c.142G>T; p.G48*; 6:52796312-52796312

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Nonsense

c.272+1G>T; p.?; 6:52796181-52796181

 lungcarcinoma; adenocarcinomaUnknown

c.462C>A; p.S154R; 6:52792940-52792940

 lung; middle_lobecarcinoma; adenocarcinomaSubstitution - Missense

c.662G>A; p.R221K; 6:52791865-52791865

 skinmalignant_melanomaSubstitution - Missense

c.442C>A; p.L148I; 6:52792960-52792960

 lung; right_upper_lobecarcinoma; adenocarcinomaSubstitution - Missense

c.179T>G; p.I60S; 6:52796275-52796275

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.516C>T; p.S172S; 6:52792886-52792886

 skinmalignant_melanomaSubstitution - coding silent

c.392G>A; p.R131H; 6:52794147-52794147

 central_nervous_system; brainglioma; astrocytoma_Grade_IVSubstitution - Missense

c.432A>G; p.G144G; 6:52792970-52792970

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.462C>G; p.S154R; 6:52792940-52792940

 skinmalignant_melanomaSubstitution - Missense

c.239A>G; p.N80S; 6:52796215-52796215

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.536C>G; p.P179R; 6:52792866-52792866

 skinmalignant_melanomaSubstitution - Missense

c.464G>A; p.R155Q; 6:52792938-52792938

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.534C>T; p.F178F; 6:52792868-52792868

 skinmalignant_melanomaSubstitution - coding silent

c.593T>C; p.L198P; 6:52791934-52791934

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.534C>T; p.F178F; 6:52792868-52792868

 skinmalignant_melanomaSubstitution - coding silent

c.578C>A; p.T193K; 6:52791949-52791949

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.202A>G; p.T68A; 6:52796252-52796252

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.651G>A; p.R217R; 6:52791876-52791876

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.394T>C; p.Y132H; 6:52794145-52794145

 kidneycarcinoma; papillary_renal_cell_carcinomaSubstitution - Missense

c.499G>A; p.V167I; 6:52792903-52792903

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.104T>C; p.I35T; 6:52797621-52797621

 boneEwings_sarcoma-peripheral_primitive_neuroectodermal_tumourSubstitution - Missense

c.451A>G; p.N151D; 6:52792951-52792951

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.375A>G; p.K125K; 6:52794164-52794164

 haematopoietic_and_lymphoid_tissuehaematopoietic_neoplasm; acute_myeloid_leukaemiaSubstitution - coding silent

c.375A>G; p.K125K; 6:52794164-52794164

 haematopoietic_and_lymphoid_tissuehaematopoietic_neoplasm; acute_myeloid_leukaemiaSubstitution - coding silent

c.14C>T; p.P5L; 6:52799254-52799254

 skinmalignant_melanomaSubstitution - Missense

c.495C>A; p.Y165*; 6:52792907-52792907

 lung; right_upper_lobecarcinoma; adenocarcinomaSubstitution - Nonsense

c.270_271CC>TT; p.(=); 6:52796183-52796184

 skin; head_neckcarcinoma; squamous_cell_carcinomaUnknown

c.405C>T; p.A135A; 6:52794134-52794134

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.430G>C; p.G144R; 6:52792972-52792972

 ovarycarcinoma; serous_carcinomaSubstitution - Missense