Cancer metastasis database

Annotation category 5

Gene information

Gene ID 28987
Symbol

NOB1

Synonymous

ART-4|MST158|MSTP158|NOB1P|PSMD8BP1

Full name

NIN1/RPN12 binding protein 1 homolog (S. cerevisiae)

Gene description

PSMD8 binding protein 1|RNA-binding protein NOB1|adenocarcinoma antigen recognized by T lymphocytes 4|nin one binding protein|phosphorylation regulatory protein HP-10|protein ART-4

Cytoband

16q22.3

Gene type

protein-coding

Synonymous

MIM:613586; HGNC:HGNC:29540; Ensembl:ENSG00000141101; HPRD:11395; Vega:OTTHUMG00000137576

COSMIC somatic mutation

Mutation (CDS; AA; Chr)

Site

Histology

Mutation Type

c.728A>G; p.N243S; 16:69748328-69748328

 breastcarcinoma; basal_(triple-negative)_carcinomaSubstitution - Missense

c.1141C>T; p.R381C; 16:69742430-69742430

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Missense

c.63+1G>T; p.?; 16:69754847-69754847

 oesophagus; lower_thirdcarcinoma; squamous_cell_carcinomaUnknown

c.845G>A; p.R282Q; 16:69744997-69744997

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.246G>A; p.T82T; 16:69752322-69752322

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.1080C>T; p.N360N; 16:69742491-69742491

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - coding silent

c.789C>A; p.A263A; 16:69748267-69748267

 livercarcinomaSubstitution - coding silent

c.168G>T; p.K56N; 16:69754622-69754622

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.567_569delGGA; p.E191delE; 16:69749075-69749077

 large_intestine; rectumcarcinoma; adenocarcinomaDeletion - In frame

c.567_569delGGA; p.E191delE; 16:69749075-69749077

 large_intestine; rectumcarcinoma; adenocarcinomaDeletion - In frame

c.567_569delGGA; p.E191delE; 16:69749075-69749077

 large_intestine; caecumcarcinoma; adenocarcinomaDeletion - In frame

c.806G>A; p.R269H; 16:69748250-69748250

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.613G>T; p.G205W; 16:69749031-69749031

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.843C>T; p.S281S; 16:69744999-69744999

 skinmalignant_melanomaSubstitution - coding silent

c.897C>T; p.T299T; 16:69744945-69744945

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - coding silent

c.1102G>A; p.A368T; 16:69742469-69742469

 biliary_tract; bile_ductcarcinoma; adenocarcinomaSubstitution - Missense

c.400-7A>G; p.?; 16:69749345-69749345

 livercarcinomaUnknown

c.217A>G; p.T73A; 16:69752351-69752351

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.1188G>C; p.R396R; 16:69742383-69742383

 cervixcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.400-7A>G; p.?; 16:69749345-69749345

 livercarcinomaUnknown

c.1034G>A; p.R345H; 16:69742537-69742537

 pancreascarcinomaSubstitution - Missense

c.125C>T; p.T42I; 16:69754665-69754665

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.138C>G; p.L46L; 16:69754652-69754652

 breastcarcinomaSubstitution - coding silent

c.231delC; p.S78fs*26; 16:69752337-69752337

 large_intestine; coloncarcinoma; adenocarcinomaDeletion - Frameshift

c.806G>T; p.R269L; 16:69748250-69748250

 central_nervous_system; brainglioma; astrocytoma_Grade_IVSubstitution - Missense

c.43C>T; p.L15L; 16:69754868-69754868

 thyroidother; neoplasmSubstitution - coding silent

c.324G>A; p.Q108Q; 16:69752244-69752244

 upper_aerodigestive_tract; mouthcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.775C>T; p.L259L; 16:69748281-69748281

 oesophaguscarcinomaSubstitution - coding silent

c.543C>T; p.D181D; 16:69749101-69749101

 oesophagus; lower_thirdcarcinoma; adenocarcinomaSubstitution - coding silent

c.516G>T; p.Q172H; 16:69749222-69749222

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.332A>T; p.K111M; 16:69749626-69749626

 livercarcinomaSubstitution - Missense

c.488C>T; p.P163L; 16:69749250-69749250

 NSmalignant_melanomaSubstitution - Missense

c.1188G>A; p.R396R; 16:69742383-69742383

 urinary_tract; bladdercarcinomaSubstitution - coding silent

c.692G>A; p.R231Q; 16:69748952-69748952

 thyroidother; neoplasmSubstitution - Missense

c.672T>C; p.C224C; 16:69748972-69748972

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - coding silent

c.263C>T; p.A88V; 16:69752305-69752305

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.966C>T; p.L322L; 16:69744876-69744876

 skinmalignant_melanomaSubstitution - coding silent

c.824+1G>T; p.?; 16:69748231-69748231

 large_intestine; rectumcarcinoma; adenocarcinomaUnknown

c.1138A>G; p.S380G; 16:69742433-69742433

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.1033C>T; p.R345C; 16:69742538-69742538

 urinary_tract; bladdercarcinomaSubstitution - Missense

c.77A>T; p.N26I; 16:69754713-69754713

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.761C>T; p.A254V; 16:69748295-69748295

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.761C>T; p.A254V; 16:69748295-69748295

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.106G>T; p.E36*; 16:69754684-69754684

 skinmalignant_melanomaSubstitution - Nonsense

c.156G>A; p.E52E; 16:69754634-69754634

 lungcarcinoma; adenocarcinomaSubstitution - coding silent

c.864T>C; p.C288C; 16:69744978-69744978

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.678C>T; p.V226V; 16:69748966-69748966

 skinmalignant_melanomaSubstitution - coding silent

c.934C>T; p.R312C; 16:69744908-69744908

 skinmalignant_melanomaSubstitution - Missense

c.678C>T; p.V226V; 16:69748966-69748966

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.583G>A; p.E195K; 16:69749061-69749061

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.1002C>T; p.Y334Y; 16:69742569-69742569

 large_intestinecarcinoma; adenocarcinomaSubstitution - coding silent

c.1002C>T; p.Y334Y; 16:69742569-69742569

 large_intestinecarcinoma; adenocarcinomaSubstitution - coding silent

c.772A>C; p.M258L; 16:69748284-69748284

 skinmalignant_melanomaSubstitution - Missense

c.568G>T; p.E190*; 16:69749076-69749076

 skinmalignant_melanomaSubstitution - Nonsense

c.1091C>T; p.P364L; 16:69742480-69742480

 skinmalignant_melanomaSubstitution - Missense