lung cancer gene and literature database Home

Annotation category 5

Basic annotation
Ontology and pathways
Literature evidence
Curated literatures
Expression
Gene expression chart
Somatic mutation
COSMIC and TCGA mutations
Network
Gene interaction
ceRNA
Gene-related ceRNA

Gene information

Gene ID	284
Symbol	ANGPT1
Synonymous	AGP1\|AGPT\|ANG1
Full name	angiopoietin 1
Gene description	ANG-1\|angiopoietin-1
Cytoband	8q23.1
Gene type	protein-coding
Synonymous	MIM:601667; HGNC:HGNC:484; Ensembl:ENSG00000154188; HPRD:03392; Vega:OTTHUMG00000164812

COSMIC somatic mutation

Mutation (CDS; AA; Chr)	Site	Histology	Mutation Type
c.604G>A; p.E202K; 8:107322100-107322100	upper_aerodigestive_tract; mouth	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.604G>A; p.E202K; 8:107322100-107322100	upper_aerodigestive_tract; mouth	carcinoma	Substitution - Missense
c.565G>A; p.E189K; 8:107336160-107336160	skin	malignant_melanoma	Substitution - Missense
c.1388C>G; p.A463G; 8:107251961-107251961	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.701A>G; p.E234G; 8:107322003-107322003	skin	malignant_melanoma	Substitution - Missense
c.441T>A; p.D147E; 8:107346954-107346954	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.1008C>A; p.F336L; 8:107293963-107293963	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.821G>A; p.G274E; 8:107303352-107303352	skin	malignant_melanoma	Substitution - Missense
c.821G>A; p.G274E; 8:107303352-107303352	skin	malignant_melanoma	Substitution - Missense
c.1311A>G; p.K437K; 8:107264243-107264243	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - coding silent
c.821G>A; p.G274E; 8:107303352-107303352	skin	malignant_melanoma	Substitution - Missense
c.821G>A; p.G274E; 8:107303352-107303352	skin; arm	malignant_melanoma	Substitution - Missense
c.767A>G; p.D256G; 8:107321937-107321937	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.1268A>C; p.D423A; 8:107264286-107264286	stomach	carcinoma; intestinal_adenocarcinoma	Substitution - Missense
c.1235G>A; p.G412E; 8:107264319-107264319	skin	malignant_melanoma	Substitution - Missense
c.275A>C; p.N92T; 8:107497284-107497284	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1024G>A; p.E342K; 8:107293947-107293947	skin	malignant_melanoma	Substitution - Missense
c.1024G>A; p.E342K; 8:107293947-107293947	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1235G>A; p.G412E; 8:107264319-107264319	skin	malignant_melanoma	Substitution - Missense
c.1235G>A; p.G412E; 8:107264319-107264319	skin	malignant_melanoma	Substitution - Missense
c.64C>G; p.Q22E; 8:107497495-107497495	breast	carcinoma	Substitution - Missense
c.1235G>A; p.G412E; 8:107264319-107264319	skin; arm	malignant_melanoma	Substitution - Missense
c.562C>T; p.H188Y; 8:107336163-107336163	skin	malignant_melanoma	Substitution - Missense
c.1037G>A; p.G346D; 8:107284847-107284847	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.439G>A; p.D147N; 8:107346956-107346956	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.142C>T; p.P48S; 8:107497417-107497417	skin	malignant_melanoma	Substitution - Missense
c.1456C>T; p.R486C; 8:107251893-107251893	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.1333G>T; p.G445*; 8:107264221-107264221	lung	carcinoma; adenocarcinoma	Substitution - Nonsense
c.64C>T; p.Q22*; 8:107497495-107497495	upper_aerodigestive_tract; mouth	carcinoma; squamous_cell_carcinoma	Substitution - Nonsense
c.1166A>G; p.D389G; 8:107284718-107284718	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.663C>G; p.G221G; 8:107322041-107322041	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.1151C>T; p.A384V; 8:107284733-107284733	skin; scalp	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.40C>T; p.L14L; 8:107497519-107497519	urinary_tract; bladder	carcinoma	Substitution - coding silent
c.1001T>C; p.L334P; 8:107293970-107293970	liver	carcinoma	Substitution - Missense
c.1181G>A; p.G394E; 8:107284703-107284703	skin	malignant_melanoma	Substitution - Missense
c.886A>G; p.S296G; 8:107303287-107303287	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1181G>A; p.G394E; 8:107284703-107284703	skin	malignant_melanoma	Substitution - Missense
c.832G>A; p.E278K; 8:107303341-107303341	skin	malignant_melanoma	Substitution - Missense
c.1181G>A; p.G394E; 8:107284703-107284703	skin; upper_leg	malignant_melanoma	Substitution - Missense
c.1388C>T; p.A463V; 8:107251961-107251961	stomach	carcinoma; intestinal_adenocarcinoma	Substitution - Missense
c.1388C>T; p.A463V; 8:107251961-107251961	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.329C>T; p.S110L; 8:107347066-107347066	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.329C>T; p.S110L; 8:107347066-107347066	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1075G>A; p.E359K; 8:107284809-107284809	skin	malignant_melanoma	Substitution - Missense
c.970A>G; p.T324A; 8:107294001-107294001	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.603G>A; p.M201I; 8:107322101-107322101	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.398G>A; p.S133N; 8:107346997-107346997	skin	malignant_melanoma	Substitution - Missense
c.754C>T; p.L252L; 8:107321950-107321950	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - coding silent
c.1411A>G; p.N471D; 8:107251938-107251938	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1390G>C; p.G464R; 8:107251959-107251959	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.576-1G>C; p.?; 8:107322129-107322129	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Unknown
c.640G>A; p.E214K; 8:107322064-107322064	skin; arm	malignant_melanoma	Substitution - Missense
c.640G>A; p.E214K; 8:107322064-107322064	skin	malignant_melanoma	Substitution - Missense
c.1402G>A; p.G468R; 8:107251947-107251947	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.361C>A; p.Q121K; 8:107347034-107347034	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.510C>A; p.T170T; 8:107336215-107336215	ovary	carcinoma; serous_carcinoma	Substitution - coding silent
c.757G>A; p.E253K; 8:107321947-107321947	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1389G>T; p.A463A; 8:107251960-107251960	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.155G>T; p.G52V; 8:107497404-107497404	liver	carcinoma	Substitution - Missense
c.1303A>T; p.M435L; 8:107264251-107264251	liver	carcinoma	Substitution - Missense
c.765G>A; p.M255I; 8:107321939-107321939	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.155G>T; p.G52V; 8:107497404-107497404	liver	carcinoma	Substitution - Missense
c.547G>A; p.E183K; 8:107336178-107336178	skin	malignant_melanoma	Substitution - Missense
c.547G>A; p.E183K; 8:107336178-107336178	skin	malignant_melanoma	Substitution - Missense
c.1148G>A; p.R383Q; 8:107284736-107284736	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1037G>T; p.G346V; 8:107284847-107284847	breast	carcinoma	Substitution - Missense
c.467C>A; p.T156N; 8:107336258-107336258	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.1333+1G>A; p.?; 8:107264220-107264220	skin	malignant_melanoma	Unknown
c.1035G>T; p.M345I; 8:107293936-107293936	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.211G>A; p.A71T; 8:107497348-107497348	haematopoietic_and_lymphoid_tissue; central_nervous_system	lymphoid_neoplasm; primary_central_nervous_system_lymphoma	Substitution - Missense
c.1057G>A; p.E353K; 8:107284827-107284827	skin	malignant_melanoma	Substitution - Missense
c.1143G>A; p.G381G; 8:107284741-107284741	skin	malignant_melanoma	Substitution - coding silent
c.1477C>T; p.R493*; 8:107251872-107251872	pancreas	carcinoma	Substitution - Nonsense
c.1477C>T; p.R493*; 8:107251872-107251872	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Nonsense
c.1477C>T; p.R493*; 8:107251872-107251872	pancreas	carcinoma	Substitution - Nonsense
c.1340G>A; p.W447*; 8:107252009-107252009	skin	malignant_melanoma	Substitution - Nonsense
c.447G>A; p.E149E; 8:107346948-107346948	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.660A>G; p.Q220Q; 8:107322044-107322044	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - coding silent
c.660A>G; p.Q220Q; 8:107322044-107322044	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.985C>T; p.R329C; 8:107293986-107293986	skin	malignant_melanoma	Substitution - Missense
c.985C>T; p.R329C; 8:107293986-107293986	skin	malignant_melanoma	Substitution - Missense
c.158A>T; p.N53I; 8:107497401-107497401	pancreas	carcinoma	Substitution - Missense
c.158A>T; p.N53I; 8:107497401-107497401	pancreas	carcinoma	Substitution - Missense
c.750G>T; p.Q250H; 8:107321954-107321954	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.879T>C; p.F293F; 8:107303294-107303294	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.250C>T; p.Q84*; 8:107497309-107497309	urinary_tract; bladder	carcinoma	Substitution - Nonsense
c.661G>A; p.G221S; 8:107322043-107322043	skin	malignant_melanoma	Substitution - Missense
c.124G>A; p.A42T; 8:107497435-107497435	NS	malignant_melanoma	Substitution - Missense
c.394A>G; p.T132A; 8:107347001-107347001	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1470G>A; p.M490I; 8:107251879-107251879	skin	malignant_melanoma	Substitution - Missense
c.965G>T; p.G322V; 8:107294006-107294006	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.907A>G; p.I303V; 8:107303266-107303266	breast	carcinoma	Substitution - Missense
c.1328C>T; p.T443I; 8:107264226-107264226	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1232C>A; p.A411E; 8:107264322-107264322	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1232C>A; p.A411E; 8:107264322-107264322	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.109C>A; p.Q37K; 8:107497450-107497450	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.797C>G; p.T266S; 8:107321907-107321907	breast	carcinoma	Substitution - Missense
c.1373G>A; p.G458E; 8:107251976-107251976	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1457G>A; p.R486H; 8:107251892-107251892	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.841C>T; p.P281S; 8:107303332-107303332	skin	malignant_melanoma	Substitution - Missense
c.342G>C; p.Q114H; 8:107347053-107347053	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.476T>C; p.L159P; 8:107336249-107336249	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.15T>A; p.L5L; 8:107497544-107497544	liver	carcinoma	Substitution - coding silent
c.15T>A; p.L5L; 8:107497544-107497544	liver	carcinoma	Substitution - coding silent
c.395C>T; p.T132I; 8:107347000-107347000	skin; trunk	malignant_melanoma	Substitution - Missense
c.809T>C; p.L270S; 8:107303364-107303364	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.1473G>A; p.M491I; 8:107251876-107251876	skin	malignant_melanoma	Substitution - Missense
c.1473G>A; p.M491I; 8:107251876-107251876	skin	malignant_melanoma	Substitution - Missense
c.376A>G; p.T126A; 8:107347019-107347019	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.681A>C; p.T227T; 8:107322023-107322023	skin	malignant_melanoma	Substitution - coding silent
c.1132G>A; p.D378N; 8:107284752-107284752	skin	malignant_melanoma	Substitution - Missense
c.1132G>A; p.D378N; 8:107284752-107284752	skin	malignant_melanoma	Substitution - Missense
c.1132G>A; p.D378N; 8:107284752-107284752	skin	malignant_melanoma	Substitution - Missense
c.1132G>A; p.D378N; 8:107284752-107284752	skin	malignant_melanoma	Substitution - Missense
c.1070G>A; p.G357E; 8:107284814-107284814	skin	malignant_melanoma	Substitution - Missense
c.676C>G; p.Q226E; 8:107322028-107322028	prostate	carcinoma	Substitution - Missense
c.854_855insAA; p.C285fs*1; 8:107303318-107303319	ovary	carcinoma; serous_carcinoma	Insertion - Frameshift
c.1416G>A; p.G472G; 8:107251933-107251933	skin	malignant_melanoma	Substitution - coding silent
c.700G>A; p.E234K; 8:107322004-107322004	skin	malignant_melanoma	Substitution - Missense
c.477T>C; p.L159L; 8:107336248-107336248	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.405C>G; p.L135L; 8:107346990-107346990	breast	carcinoma	Substitution - coding silent
c.1187A>G; p.E396G; 8:107284697-107284697	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.738C>T; p.V246V; 8:107321966-107321966	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.738C>T; p.V246V; 8:107321966-107321966	skin	malignant_melanoma	Substitution - coding silent
c.899C>T; p.T300I; 8:107303274-107303274	skin	malignant_melanoma	Substitution - Missense
c.1478G>A; p.R493Q; 8:107251871-107251871	pancreas	carcinoma	Substitution - Missense
c.1478G>A; p.R493Q; 8:107251871-107251871	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.17_21delCCTTT; p.S6fs*27; 8:107497538-107497542	large_intestine; caecum	carcinoma; adenocarcinoma	Deletion - Frameshift
c.1478G>A; p.R493Q; 8:107251871-107251871	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.12C>T; p.F4F; 8:107497547-107497547	skin	malignant_melanoma	Substitution - coding silent
c.12C>T; p.F4F; 8:107497547-107497547	skin	malignant_melanoma	Substitution - coding silent
c.1215A>G; p.K405K; 8:107264339-107264339	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - coding silent
c.535C>T; p.Q179*; 8:107336190-107336190	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Nonsense
c.201G>A; p.L67L; 8:107497358-107497358	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.1223C>A; p.T408N; 8:107264331-107264331	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.663C>T; p.G221G; 8:107322041-107322041	skin	malignant_melanoma	Substitution - coding silent
c.762G>T; p.L254L; 8:107321942-107321942	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.655C>A; p.L219I; 8:107322049-107322049	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1267G>A; p.D423N; 8:107264287-107264287	skin	malignant_melanoma	Substitution - Missense
c.1066C>T; p.L356L; 8:107284818-107284818	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.1066C>T; p.L356L; 8:107284818-107284818	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.228G>T; p.P76P; 8:107497331-107497331	breast	carcinoma	Substitution - coding silent
c.489G>A; p.L163L; 8:107336236-107336236	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.664T>C; p.L222L; 8:107322040-107322040	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.1198T>C; p.Y400H; 8:107284686-107284686	salivary_gland; parotid	carcinoma; adenoid_cystic_carcinoma	Substitution - Missense
c.887G>T; p.S296I; 8:107303286-107303286	lung	carcinoma; small_cell_carcinoma	Substitution - Missense
c.790C>G; p.L264V; 8:107321914-107321914	breast	carcinoma	Substitution - Missense
c.1421A>C; p.K474T; 8:107251928-107251928	pancreas	carcinoma	Substitution - Missense
c.1382A>G; p.Y461C; 8:107251967-107251967	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.370A>T; p.T124S; 8:107347025-107347025	lung	carcinoma; small_cell_carcinoma	Substitution - Missense
c.375T>C; p.A125A; 8:107347020-107347020	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - coding silent
c.1057G>T; p.E353*; 8:107284827-107284827	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Nonsense
c.673C>T; p.R225C; 8:107322031-107322031	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.333G>A; p.E111E; 8:107347062-107347062	liver	carcinoma	Substitution - coding silent
c.333G>A; p.E111E; 8:107347062-107347062	liver	carcinoma	Substitution - coding silent
c.396C>A; p.T132T; 8:107346999-107346999	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.409C>G; p.Q137E; 8:107346986-107346986	breast	carcinoma	Substitution - Missense
c.396C>A; p.T132T; 8:107346999-107346999	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.388A>T; p.I130L; 8:107347007-107347007	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.1354G>A; p.G452S; 8:107251995-107251995	skin	malignant_melanoma	Substitution - Missense
c.690C>T; p.I230I; 8:107322014-107322014	skin	malignant_melanoma	Substitution - coding silent
c.587A>C; p.H196P; 8:107322117-107322117	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.829G>A; p.E277K; 8:107303344-107303344	skin	malignant_melanoma	Substitution - Missense
c.1023G>T; p.K341N; 8:107293948-107293948	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1481C>T; p.P494L; 8:107251868-107251868	skin	malignant_melanoma	Substitution - Missense
c.781C>T; p.L261F; 8:107321923-107321923	skin	malignant_melanoma	Substitution - Missense
c.1203G>C; p.R401S; 8:107264351-107264351	skin	malignant_melanoma	Substitution - Missense
c.594C>T; p.I198I; 8:107322110-107322110	skin	malignant_melanoma	Substitution - coding silent
c.385G>A; p.E129K; 8:107347010-107347010	skin	malignant_melanoma	Substitution - Missense
c.510C>T; p.T170T; 8:107336215-107336215	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.351G>C; p.Q117H; 8:107347044-107347044	breast	carcinoma	Substitution - Missense
c.174G>T; p.T58T; 8:107497385-107497385	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - coding silent
c.432G>A; p.K144K; 8:107346963-107346963	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.1403G>T; p.G468V; 8:107251946-107251946	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.208_209delGA; p.D70fs*31; 8:107497350-107497351	ovary	carcinoma; serous_carcinoma	Deletion - Frameshift
c.208_209delGA; p.D70fs*31; 8:107497350-107497351	ovary	carcinoma; serous_carcinoma	Deletion - Frameshift
c.208_209delGA; p.D70fs*31; 8:107497350-107497351	ovary	carcinoma; serous_carcinoma	Deletion - Frameshift
c.208_209delGA; p.D70fs*31; 8:107497350-107497351	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.208_209delGA; p.D70fs*31; 8:107497350-107497351	ovary	carcinoma; serous_carcinoma	Deletion - Frameshift
c.208_209delGA; p.D70fs*31; 8:107497350-107497351	ovary	carcinoma; serous_carcinoma	Deletion - Frameshift
c.208_209delGA; p.D70fs*31; 8:107497350-107497351	ovary	carcinoma; serous_carcinoma	Deletion - Frameshift
c.208_209delGA; p.D70fs*31; 8:107497350-107497351	ovary	carcinoma; serous_carcinoma	Deletion - Frameshift
c.576-1G>A; p.?; 8:107322129-107322129	ovary	carcinoma; serous_carcinoma	Unknown
c.473G>A; p.R158Q; 8:107336252-107336252	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1138G>A; p.E380K; 8:107284746-107284746	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.707A>G; p.Q236R; 8:107321997-107321997	skin	malignant_melanoma	Substitution - Missense
c.621A>G; p.E207E; 8:107322083-107322083	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.1180G>A; p.G394R; 8:107284704-107284704	skin	malignant_melanoma	Substitution - Missense
c.888T>A; p.S296R; 8:107303285-107303285	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.843A>T; p.P281P; 8:107303330-107303330	breast	carcinoma	Substitution - coding silent
c.917T>C; p.M306T; 8:107303256-107303256	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.145G>C; p.E49Q; 8:107497414-107497414	liver	carcinoma	Substitution - Missense
c.893T>C; p.I298T; 8:107303280-107303280	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.145G>C; p.E49Q; 8:107497414-107497414	liver	carcinoma	Substitution - Missense
c.1357C>T; p.P453S; 8:107251992-107251992	skin	malignant_melanoma	Substitution - Missense
c.966T>A; p.G322G; 8:107294005-107294005	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.27C>T; p.F9F; 8:107497532-107497532	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - coding silent
c.43A>G; p.T15A; 8:107497516-107497516	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.367C>T; p.H123Y; 8:107347028-107347028	skin	malignant_melanoma	Substitution - Missense
c.852C>T; p.D284D; 8:107303321-107303321	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.704A>G; p.K235R; 8:107322000-107322000	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; mantle_cell_lymphoma	Substitution - Missense
c.1247G>A; p.S416N; 8:107264307-107264307	skin; mucosal	malignant_melanoma	Substitution - Missense
c.576-5T>A; p.?; 8:107322133-107322133	lung	carcinoma; squamous_cell_carcinoma	Unknown
c.410A>G; p.Q137R; 8:107346985-107346985	upper_aerodigestive_tract; mouth	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.648A>C; p.K216N; 8:107322056-107322056	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.801A>G; p.K267K; 8:107321903-107321903	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1101G>A; p.Q367Q; 8:107284783-107284783	skin	malignant_melanoma	Substitution - coding silent
c.1298A>G; p.N433S; 8:107264256-107264256	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1403G>A; p.G468E; 8:107251946-107251946	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1403G>A; p.G468E; 8:107251946-107251946	skin	malignant_melanoma	Substitution - Missense
c.1403G>A; p.G468E; 8:107251946-107251946	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1403G>A; p.G468E; 8:107251946-107251946	skin	malignant_melanoma	Substitution - Missense
c.656T>C; p.L219P; 8:107322048-107322048	liver	carcinoma	Substitution - Missense
c.656T>C; p.L219P; 8:107322048-107322048	liver	carcinoma; hepatocellular_carcinoma	Substitution - Missense
c.139C>T; p.L47F; 8:107497420-107497420	pancreas	carcinoma	Substitution - Missense
c.411G>A; p.Q137Q; 8:107346984-107346984	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.793T>C; p.C265R; 8:107321911-107321911	oesophagus; lower_third	carcinoma; adenocarcinoma	Substitution - Missense
c.945T>A; p.N315K; 8:107294026-107294026	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.945T>A; p.N315K; 8:107294026-107294026	liver	carcinoma	Substitution - Missense
c.446A>G; p.E149G; 8:107346949-107346949	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.301G>A; p.E101K; 8:107347094-107347094	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.301G>A; p.E101K; 8:107347094-107347094	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1426C>T; p.H476Y; 8:107251923-107251923	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.962G>A; p.G321E; 8:107294009-107294009	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.392G>A; p.G131E; 8:107347003-107347003	skin; head_neck	malignant_melanoma; superficial_spreading	Substitution - Missense
c.1451C>T; p.S484F; 8:107251898-107251898	skin	malignant_melanoma	Substitution - Missense
c.392G>A; p.G131E; 8:107347003-107347003	skin	malignant_melanoma	Substitution - Missense
c.987T>C; p.R329R; 8:107293984-107293984	central_nervous_system; brain	glioma	Substitution - coding silent
c.848G>A; p.R283K; 8:107303325-107303325	skin	malignant_melanoma	Substitution - Missense
c.1482T>A; p.P494P; 8:107251867-107251867	skin	malignant_melanoma	Substitution - coding silent

Annotation category 5

Basic annotation

Literature evidence

Expression

Somatic mutation

Network

ceRNA

Gene information

COSMIC somatic mutation