Cancer metastasis database

Annotation category 5

Gene information

Gene ID 2833
Symbol

CXCR3

Synonymous

CD182|CD183|CKR-L2|CMKAR3|GPR9|IP10-R|Mig-R|MigR

Full name

chemokine (C-X-C motif) receptor 3

Gene description

C-X-C chemokine receptor type 3|G protein-coupled receptor 9|IP-10 receptor|Mig receptor|interferon-inducible protein 10 receptor

Cytoband

Xq13

Gene type

protein-coding

Synonymous

MIM:300574; HGNC:HGNC:4540; Ensembl:ENSG00000186810; HPRD:02936; Vega:OTTHUMG00000033326

COSMIC somatic mutation

Mutation (CDS; AA; Chr)

Site

Histology

Mutation Type

c.242G>A; p.R81Q; 23:71617230-71617230

central_nervous_system; brainatypical_teratoid-rhabdoid_tumourSubstitution - Missense

c.756G>A; p.R252R; 23:71616716-71616716

skinmalignant_melanomaSubstitution - coding silent

c.19G>A; p.D7N; 23:71617453-71617453

ovarycarcinoma; serous_carcinomaSubstitution - Missense

c.1079C>A; p.T360N; 23:71616393-71616393

breastcarcinomaSubstitution - Missense

c.20A>G; p.D7G; 23:71617452-71617452

large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.944C>T; p.P315L; 23:71616528-71616528

large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.944C>T; p.P315L; 23:71616528-71616528

skinmalignant_melanomaSubstitution - Missense

c.808C>A; p.P270T; 23:71616664-71616664

thyroidother; neoplasmSubstitution - Missense

c.494delC; p.P165fs*4; 23:71616978-71616978

large_intestine; coloncarcinoma; adenocarcinomaDeletion - Frameshift

c.429C>G; p.A143A; 23:71617043-71617043

lungcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.945G>A; p.P315P; 23:71616527-71616527

large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - coding silent

c.1107+3C>T; p.?; 23:71616362-71616362

central_nervous_system; brainglioma; astrocytoma_Grade_IVUnknown

c.230T>A; p.V77E; 23:71617242-71617242

lung; right_lower_lobecarcinoma; adenocarcinomaSubstitution - Missense

c.1014C>T; p.C338C; 23:71616458-71616458

lungcarcinoid-endocrine_tumour; atypicalSubstitution - coding silent

c.320C>T; p.P107L; 23:71617152-71617152

breastcarcinomaSubstitution - Missense

c.129C>T; p.C43C; 23:71617343-71617343

large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.501C>T; p.R167R; 23:71616971-71616971

large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - coding silent

c.943C>T; p.P315S; 23:71616529-71616529

lung; right_upper_lobecarcinoma; adenocarcinomaSubstitution - Missense

c.1028G>A; p.G343E; 23:71616444-71616444

skinmalignant_melanomaSubstitution - Missense

c.14T>A; p.V5E; 23:71617458-71617458

ovaryother; neoplasmSubstitution - Missense

c.902C>T; p.S301L; 23:71616570-71616570

endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.299C>T; p.T100M; 23:71617173-71617173

oesophaguscarcinoma; adenocarcinomaSubstitution - Missense

c.877G>T; p.E293*; 23:71616595-71616595

ovarycarcinoma; serous_carcinomaSubstitution - Nonsense

c.476T>A; p.L159H; 23:71616996-71616996

breastcarcinomaSubstitution - Missense

c.107C>T; p.S36L; 23:71617365-71617365

breastcarcinomaSubstitution - Missense

c.862C>T; p.R288C; 23:71616610-71616610

urinary_tract; bladdercarcinomaSubstitution - Missense

c.389T>C; p.L130P; 23:71617083-71617083

large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - Missense

c.507C>A; p.T169T; 23:71616965-71616965

lungcarcinoma; adenocarcinomaSubstitution - coding silent

c.852C>T; p.G284G; 23:71616620-71616620

stomachcarcinoma; adenocarcinomaSubstitution - coding silent

c.556G>A; p.D186N; 23:71616916-71616916

endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.485G>A; p.R162Q; 23:71616987-71616987

large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.583G>A; p.D195N; 23:71616889-71616889

lungcarcinoma; adenocarcinomaSubstitution - Missense

c.583G>A; p.D195N; 23:71616889-71616889

skinmalignant_melanomaSubstitution - Missense

c.305T>C; p.L102P; 23:71617167-71617167

skinmalignant_melanomaSubstitution - Missense

c.879A>C; p.E293D; 23:71616593-71616593

skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.384T>G; p.G128G; 23:71617088-71617088

thyroidother; neoplasmSubstitution - coding silent

c.384T>G; p.G128G; 23:71617088-71617088

thyroidother; neoplasmSubstitution - coding silent

c.384T>G; p.G128G; 23:71617088-71617088

thyroidother; neoplasmSubstitution - coding silent

c.384T>G; p.G128G; 23:71617088-71617088

thyroidother; neoplasmSubstitution - coding silent

c.500G>A; p.R167H; 23:71616972-71616972

large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.582C>T; p.H194H; 23:71616890-71616890

breastcarcinomaSubstitution - coding silent

c.500G>A; p.R167H; 23:71616972-71616972

ovarycarcinoma; serous_carcinomaSubstitution - Missense

c.797T>G; p.L266R; 23:71616675-71616675

skinmalignant_melanomaSubstitution - Missense

c.547G>A; p.A183T; 23:71616925-71616925

breastcarcinomaSubstitution - Missense

c.241C>T; p.R81W; 23:71617231-71617231

large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.1058G>A; p.R353Q; 23:71616414-71616414

large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.300G>A; p.T100T; 23:71617172-71617172

lungcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.839T>C; p.L280P; 23:71616633-71616633

endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.800G>T; p.C267F; 23:71616672-71616672

lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.363T>A; p.S121S; 23:71617109-71617109

ovarycarcinoma; serous_carcinomaSubstitution - coding silent

c.724C>T; p.L242L; 23:71616748-71616748

stomachcarcinoma; adenocarcinomaSubstitution - coding silent

c.875G>A; p.R292Q; 23:71616597-71616597

skinmalignant_melanomaSubstitution - Missense

c.586G>A; p.E196K; 23:71616886-71616886

large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - Missense

c.295G>A; p.D99N; 23:71617177-71617177

breastcarcinomaSubstitution - Missense

c.213C>T; p.N71N; 23:71617259-71617259

central_nervous_system; braingliomaSubstitution - coding silent

c.502G>A; p.V168M; 23:71616970-71616970

endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.48delT; p.A17fs*33; 23:71617424-71617424

endometriumcarcinoma; endometrioid_carcinomaDeletion - Frameshift

c.132A>C; p.P44P; 23:71617340-71617340

urinary_tract; bladdercarcinomaSubstitution - coding silent

c.314C>A; p.T105K; 23:71617158-71617158

kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - Missense

c.153C>T; p.F51F; 23:71617319-71617319

endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.142A>T; p.S48C; 23:71617330-71617330

lungcarcinoma; adenocarcinomaSubstitution - Missense

c.165C>T; p.F55F; 23:71617307-71617307

large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - coding silent

c.652C>T; p.L218L; 23:71616820-71616820

large_intestinecarcinoma; adenocarcinomaSubstitution - coding silent

c.652C>T; p.L218L; 23:71616820-71616820

large_intestinecarcinoma; adenocarcinomaSubstitution - coding silent

c.46G>A; p.V16I; 23:71617426-71617426

boneEwings_sarcoma-peripheral_primitive_neuroectodermal_tumourSubstitution - Missense