Cancer metastasis database

Annotation category 5

Gene information

Gene ID 2810
Symbol

SFN

Synonymous

YWHAS

Full name

stratifin

Gene description

14-3-3 protein sigma|14-3-3 sigma|epithelial cell marker protein 1

Cytoband

1p36.11

Gene type

protein-coding

Synonymous

MIM:601290; HGNC:HGNC:10773; Ensembl:ENSG00000175793; HPRD:03185; Vega:OTTHUMG00000004093

COSMIC somatic mutation

Mutation (CDS; AA; Chr)

Site

Histology

Mutation Type

c.34C>T; p.L12L; 1:26863246-26863246

 breastcarcinomaSubstitution - coding silent

c.334G>T; p.G112W; 1:26863546-26863546

 central_nervous_system; brainglioma; astrocytoma_Grade_IVSubstitution - Missense

c.176G>A; p.W59*; 1:26863388-26863388

 boneEwings_sarcoma-peripheral_primitive_neuroectodermal_tumourSubstitution - Nonsense

c.52C>T; p.R18C; 1:26863264-26863264

 livercarcinomaSubstitution - Missense

c.732G>A; p.Q244Q; 1:26863944-26863944

 skinmalignant_melanomaSubstitution - coding silent

c.93G>C; p.E31D; 1:26863305-26863305

 urinary_tract; bladdercarcinomaSubstitution - Missense

c.610G>A; p.D204N; 1:26863822-26863822

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.733G>A; p.E245K; 1:26863945-26863945

 skinmalignant_melanomaSubstitution - Missense

c.562G>C; p.E188Q; 1:26863774-26863774

 cervixcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.369G>T; p.M123I; 1:26863581-26863581

 breastcarcinomaSubstitution - Missense

c.238G>C; p.E80Q; 1:26863450-26863450

 lung; right_upper_lobecarcinoma; adenocarcinomaSubstitution - Missense

c.212A>G; p.E71G; 1:26863424-26863424

 kidneycarcinoma; papillary_renal_cell_carcinomaSubstitution - Missense

c.488C>T; p.P163L; 1:26863700-26863700

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.376G>A; p.D126N; 1:26863588-26863588

 haematopoietic_and_lymphoid_tissuelymphoid_neoplasm; acute_lymphoblastic_leukaemiaSubstitution - Missense

c.147G>C; p.K49N; 1:26863359-26863359

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.36G>A; p.L12L; 1:26863248-26863248

 skin; head_neckmalignant_melanoma; superficial_spreadingSubstitution - coding silent

c.114C>T; p.C38C; 1:26863326-26863326

 haematopoietic_and_lymphoid_tissuelymphoid_neoplasm; acute_lymphoblastic_T_cell_leukaemiaSubstitution - coding silent

c.114C>T; p.C38C; 1:26863326-26863326

 haematopoietic_and_lymphoid_tissuelymphoid_neoplasm; acute_lymphoblastic_T_cell_leukaemiaSubstitution - coding silent

c.294C>G; p.T98T; 1:26863506-26863506

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.289G>A; p.D97N; 1:26863501-26863501

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - Missense

c.96G>T; p.K32N; 1:26863308-26863308

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.579G>A; p.L193L; 1:26863791-26863791

 lungcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.251A>G; p.Y84C; 1:26863463-26863463

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.228G>A; p.E76E; 1:26863440-26863440

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.228G>A; p.E76E; 1:26863440-26863440

 stomachcarcinoma; adenocarcinomaSubstitution - coding silent

c.108C>G; p.L36L; 1:26863320-26863320

 pancreascarcinomaSubstitution - coding silent

c.415_417delGAC; p.D139delD; 1:26863627-26863629

 large_intestine; coloncarcinoma; adenocarcinomaDeletion - In frame

c.24G>A; p.Q8Q; 1:26863236-26863236

 urinary_tract; bladdercarcinomaSubstitution - coding silent

c.12C>A; p.A4A; 1:26863224-26863224

 livercarcinomaSubstitution - coding silent

c.477G>A; p.K159K; 1:26863689-26863689

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.221C>T; p.S74L; 1:26863433-26863433

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.412_414delGAC; p.D139delD; 1:26863624-26863626

 large_intestinecarcinoma; adenocarcinomaDeletion - In frame

c.337G>A; p.D113N; 1:26863549-26863549

 skinmalignant_melanomaSubstitution - Missense

c.131T>A; p.L44H; 1:26863343-26863343

 breastcarcinoma; basal_(triple-negative)_carcinomaSubstitution - Missense

c.515T>A; p.L172Q; 1:26863727-26863727

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.397G>A; p.E133K; 1:26863609-26863609

 skin; scalpcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.732G>T; p.Q244H; 1:26863944-26863944

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.664C>A; p.L222M; 1:26863876-26863876

 central_nervous_system; brainstemglioma; astrocytoma_Grade_IVSubstitution - Missense

c.18G>T; p.L6L; 1:26863230-26863230

 breastcarcinomaSubstitution - coding silent