lung cancer gene and literature database Home

Annotation category 5

Basic annotation
Ontology and pathways
Literature evidence
Curated literatures
Expression
Gene expression chart
Somatic mutation
COSMIC and TCGA mutations
Network
Gene interaction
ceRNA
Gene-related ceRNA

Gene information

Gene ID	27346
Symbol	TMEM97
Synonymous	MAC30
Full name	transmembrane protein 97
Gene description	-
Cytoband	17q11.2
Gene type	protein-coding
Synonymous	MIM:612912; HGNC:HGNC:28106; Ensembl:ENSG00000109084; HPRD:14343; Vega:OTTHUMG00000132497

COSMIC somatic mutation

Mutation (CDS; AA; Chr)	Site	Histology	Mutation Type
c.290G>A; p.R97Q; 17:28326552-28326552	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.426C>T; p.T142T; 17:28326688-28326688	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - coding silent
c.264C>T; p.F88F; 17:28325640-28325640	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.518_519insA; p.*177fs?; 17:28326780-28326781	large_intestine; caecum	carcinoma; adenocarcinoma	Insertion - Frameshift
c.518_519insA; p.*177fs?; 17:28326780-28326781	skin	malignant_melanoma	Insertion - Frameshift
c.148T>C; p.Y50H; 17:28325524-28325524	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.338C>T; p.P113L; 17:28326600-28326600	stomach	carcinoma; mixed_intestinal_and_diffuse_adenocarcinoma-unclassifiable	Substitution - Missense
c.487C>T; p.R163W; 17:28326749-28326749	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.487C>T; p.R163W; 17:28326749-28326749	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.57C>T; p.L19L; 17:28319296-28319296	urinary_tract; bladder	carcinoma	Substitution - coding silent
c.519delA; p.K176fs?; 17:28326781-28326781	large_intestine; rectum	carcinoma; adenocarcinoma	Deletion - Frameshift
c.519delA; p.K176fs?; 17:28326781-28326781	lung	carcinoma; small_cell_carcinoma	Deletion - Frameshift
c.519delA; p.K176fs?; 17:28326781-28326781	large_intestine; rectum	carcinoma; adenocarcinoma	Deletion - Frameshift
c.519delA; p.K176fs?; 17:28326781-28326781	large_intestine; rectum	carcinoma; adenocarcinoma	Deletion - Frameshift
c.519delA; p.K176fs?; 17:28326781-28326781	skin; head_neck	carcinoma; squamous_cell_carcinoma	Deletion - Frameshift
c.519delA; p.K176fs?; 17:28326781-28326781	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.519delA; p.K176fs?; 17:28326781-28326781	large_intestine; caecum	carcinoma; adenocarcinoma	Deletion - Frameshift
c.519delA; p.K176fs?; 17:28326781-28326781	large_intestine; caecum	carcinoma; adenocarcinoma	Deletion - Frameshift
c.519delA; p.K176fs?; 17:28326781-28326781	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.519delA; p.K176fs?; 17:28326781-28326781	large_intestine; caecum	carcinoma; adenocarcinoma	Deletion - Frameshift
c.519delA; p.K176fs?; 17:28326781-28326781	large_intestine; caecum	carcinoma; adenocarcinoma	Deletion - Frameshift
c.519delA; p.K176fs?; 17:28326781-28326781	large_intestine; caecum	carcinoma; adenocarcinoma	Deletion - Frameshift
c.519delA; p.K176fs?; 17:28326781-28326781	stomach	carcinoma; intestinal_adenocarcinoma	Deletion - Frameshift
c.519delA; p.K176fs?; 17:28326781-28326781	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.519delA; p.K176fs?; 17:28326781-28326781	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.519delA; p.K176fs?; 17:28326781-28326781	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.519delA; p.K176fs?; 17:28326781-28326781	large_intestine; caecum	carcinoma; adenocarcinoma	Deletion - Frameshift
c.519delA; p.K176fs?; 17:28326781-28326781	large_intestine; caecum	carcinoma; adenocarcinoma	Deletion - Frameshift
c.519delA; p.K176fs?; 17:28326781-28326781	stomach	carcinoma; intestinal_adenocarcinoma	Deletion - Frameshift
c.217G>T; p.E73*; 17:28325593-28325593	lung	carcinoma; squamous_cell_carcinoma	Substitution - Nonsense
c.97G>C; p.V33L; 17:28319336-28319336	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.59G>T; p.S20I; 17:28319298-28319298	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.401C>T; p.P134L; 17:28326663-28326663	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.112C>G; p.L38V; 17:28319351-28319351	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	Substitution - Missense
c.183G>A; p.E61E; 17:28325559-28325559	lung	carcinoma; small_cell_carcinoma	Substitution - coding silent
c.10C>G; p.P4A; 17:28319249-28319249	urinary_tract; bladder	carcinoma	Substitution - Missense
c.219G>A; p.E73E; 17:28325595-28325595	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.7G>T; p.A3S; 17:28319246-28319246	liver	carcinoma	Substitution - Missense
c.7G>T; p.A3S; 17:28319246-28319246	upper_aerodigestive_tract; larynx	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.7G>T; p.A3S; 17:28319246-28319246	liver	carcinoma	Substitution - Missense
c.218A>G; p.E73G; 17:28325594-28325594	skin	malignant_melanoma	Substitution - Missense
c.493C>G; p.P165A; 17:28326755-28326755	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.21G>T; p.R7S; 17:28319260-28319260	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.357G>C; p.L119L; 17:28326619-28326619	breast	carcinoma	Substitution - coding silent

Annotation category 5

Basic annotation

Literature evidence

Expression

Somatic mutation

Network

ceRNA

Gene information

COSMIC somatic mutation