lung cancer gene and literature database Home

Annotation category 5

Basic annotation
Ontology and pathways
Literature evidence
Curated literatures
Expression
Gene expression chart
Somatic mutation
COSMIC and TCGA mutations
Network
Gene interaction
ceRNA
Gene-related ceRNA

Gene information

Gene ID	26575
Symbol	RGS17
Synonymous	RGS-17\|RGSZ2\|hRGS17
Full name	regulator of G-protein signaling 17
Gene description	-
Cytoband	6q25.3
Gene type	protein-coding
Synonymous	MIM:607191; HGNC:HGNC:14088; Ensembl:ENSG00000091844; HPRD:06223

COSMIC somatic mutation

Mutation (CDS; AA; Chr)	Site	Histology	Mutation Type
c.498C>T; p.P166P; 6:153011709-153011709	pancreas	NS	Substitution - coding silent
c.498C>T; p.P166P; 6:153011709-153011709	pancreas	carcinoma	Substitution - coding silent
c.580C>G; p.Q194E; 6:153011627-153011627	cervix	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.232G>A; p.V78I; 6:153024474-153024474	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.42C>T; p.A14A; 6:153043977-153043977	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.521C>T; p.A174V; 6:153011686-153011686	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.279A>T; p.A93A; 6:153024427-153024427	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.181A>C; p.M61L; 6:153026482-153026482	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.461G>T; p.R154L; 6:153011746-153011746	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.632A>G; p.211; 6:153011575-153011575	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.416A>G; p.D139G; 6:153024290-153024290	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.372G>T; p.Q124H; 6:153024334-153024334	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.540T>A; p.T180T; 6:153011667-153011667	kidney	carcinoma; papillary_renal_cell_carcinoma	Substitution - coding silent
c.147G>T; p.G49G; 6:153026516-153026516	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.585T>G; p.I195M; 6:153011622-153011622	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.171C>T; p.H57H; 6:153026492-153026492	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.493G>A; p.D165N; 6:153011714-153011714	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.252T>A; p.N84K; 6:153024454-153024454	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.241T>A; p.W81R; 6:153024465-153024465	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.566G>T; p.R189M; 6:153011641-153011641	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.264G>T; p.M88I; 6:153024442-153024442	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.531G>C; p.Q177H; 6:153011676-153011676	cervix	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.311C>T; p.T104I; 6:153024395-153024395	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.514G>A; p.E172K; 6:153011693-153011693	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.369G>A; p.E123E; 6:153024337-153024337	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.401G>T; p.R134M; 6:153024305-153024305	breast	carcinoma	Substitution - Missense
c.205G>A; p.E69K; 6:153026458-153026458	bone; extraskeletal	Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	Substitution - Missense
c.70C>T; p.P24S; 6:153043949-153043949	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.155C>T; p.A52V; 6:153026508-153026508	upper_aerodigestive_tract; larynx	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.155C>T; p.A52V; 6:153026508-153026508	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.155C>T; p.A52V; 6:153026508-153026508	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.54T>G; p.A18A; 6:153043965-153043965	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.54T>G; p.A18A; 6:153043965-153043965	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - coding silent
c.186G>A; p.E62E; 6:153026477-153026477	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.108C>T; p.C36C; 6:153043911-153043911	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.391G>T; p.E131*; 6:153024315-153024315	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Nonsense
c.387delT; p.I129fs*7; 6:153024319-153024319	breast	carcinoma	Deletion - Frameshift
c.234C>T; p.V78V; 6:153024472-153024472	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.96G>T; p.W32C; 6:153043923-153043923	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.84T>C; p.C28C; 6:153043935-153043935	skin	malignant_melanoma	Substitution - coding silent
c.482G>T; p.R161I; 6:153011725-153011725	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.111C>T; p.S37S; 6:153043908-153043908	prostate	adenoma	Substitution - coding silent
c.327G>T; p.E109D; 6:153024379-153024379	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.327G>T; p.E109D; 6:153024379-153024379	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.449G>C; p.S150T; 6:153011758-153011758	breast	carcinoma	Substitution - Missense
c.553G>T; p.D185Y; 6:153011654-153011654	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.553G>T; p.D185Y; 6:153011654-153011654	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.162A>G; p.R54R; 6:153026501-153026501	autonomic_ganglia	neuroblastoma	Substitution - coding silent
c.311C>G; p.T104R; 6:153024395-153024395	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.551G>A; p.R184K; 6:153011656-153011656	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.381A>C; p.K127N; 6:153024325-153024325	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.157G>A; p.G53R; 6:153026506-153026506	skin; face	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.457T>A; p.S153T; 6:153011750-153011750	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.169C>A; p.H57N; 6:153026494-153026494	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.531G>A; p.Q177Q; 6:153011676-153011676	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - coding silent
c.356A>G; p.D119G; 6:153024350-153024350	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense

Annotation category 5

Basic annotation

Literature evidence

Expression

Somatic mutation

Network

ceRNA

Gene information

COSMIC somatic mutation