Cancer metastasis database

Annotation category 5

Gene information

Gene ID 26135
Symbol

SERBP1

Synonymous

CGI-55|CHD3IP|HABP4L|PAI-RBP1|PAIRBP1

Full name

SERPINE1 mRNA binding protein 1

Gene description

PAI-1 mRNA binding protein|PAI1 RNA-binding protein 1|SERPINE1 mRNA-binding protein 1|chromodomain helicase DNA binding protein 3 interacting protein|plasminogen activator inhibitor 1 RNA binding protein|plasminogen activator inhibitor 1 RNA-binding prote

Cytoband

1p31

Gene type

protein-coding

Synonymous

MIM:607378; HGNC:HGNC:17860; Ensembl:ENSG00000142864; Vega:OTTHUMG00000009372

COSMIC somatic mutation

Mutation (CDS; AA; Chr)

Site

Histology

Mutation Type

c.959A>G; p.K320R; 1:67420046-67420046

 central_nervous_system; brainglioma; astrocytoma_Grade_IIISubstitution - Missense

c.797C>T; p.P266L; 1:67424221-67424221

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.105G>C; p.E35D; 1:67430196-67430196

 upper_aerodigestive_tract; pharynxcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.39C>G; p.V13V; 1:67430262-67430262

 skinmalignant_melanomaSubstitution - coding silent

c.229G>T; p.D77Y; 1:67430072-67430072

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.295G>C; p.V99L; 1:67430006-67430006

 oesophaguscarcinoma; adenocarcinomaSubstitution - Missense

c.822G>T; p.E274D; 1:67420183-67420183

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - Missense

c.221C>T; p.S74F; 1:67430080-67430080

 prostatecarcinoma; adenocarcinomaSubstitution - Missense

c.415G>C; p.E139Q; 1:67426184-67426184

 breastcarcinomaSubstitution - Missense

c.294C>T; p.P98P; 1:67430007-67430007

 lungcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.325G>T; p.V109F; 1:67426274-67426274

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.1220T>C; p.L407P; 1:67413214-67413214

 skinmalignant_melanomaSubstitution - Missense

c.176C>G; p.A59G; 1:67430125-67430125

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.1048G>T; p.D350Y; 1:67415288-67415288

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.530G>A; p.R177H; 1:67425158-67425158

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.171C>A; p.A57A; 1:67430130-67430130

 large_intestinecarcinoma; adenocarcinomaSubstitution - coding silent

c.288G>A; p.Q96Q; 1:67430013-67430013

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.293C>T; p.P98L; 1:67430008-67430008

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.764C>T; p.T255I; 1:67424254-67424254

 oesophagus; lower_thirdcarcinoma; adenocarcinomaSubstitution - Missense

c.1132C>T; p.R378C; 1:67415204-67415204

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.1058C>T; p.S353F; 1:67415278-67415278

 skinmalignant_melanomaSubstitution - Missense

c.494G>A; p.R165H; 1:67425194-67425194

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Missense

c.606-2_607delAGTT; p.?; 1:67424976-67424979

 large_intestine; caecumcarcinoma; adenocarcinomaUnknown

c.129G>A; p.G43G; 1:67430172-67430172

 ovarycarcinoma; serous_carcinomaSubstitution - coding silent

c.666C>A; p.H222Q; 1:67424917-67424917

 lungcarcinoma; small_cell_carcinomaSubstitution - Missense

c.605C>T; p.S202F; 1:67425083-67425083

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.1105G>A; p.G369S; 1:67415231-67415231

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.248C>T; p.P83L; 1:67430053-67430053

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.997-9T>C; p.?; 1:67415348-67415348

 pancreascarcinomaUnknown

c.424C>T; p.L142F; 1:67426175-67426175

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.699G>T; p.E233D; 1:67424319-67424319

 lung; right_upper_lobecarcinoma; adenocarcinomaSubstitution - Missense

c.550G>A; p.G184R; 1:67425138-67425138

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.523C>T; p.R175C; 1:67425165-67425165

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - Missense

c.114A>G; p.K38K; 1:67430187-67430187

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.448G>A; p.E150K; 1:67426151-67426151

 breastcarcinomaSubstitution - Missense

c.1141C>T; p.R381C; 1:67415195-67415195

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.636C>T; p.H212H; 1:67424947-67424947

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.401G>A; p.R134H; 1:67426198-67426198

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.708A>T; p.K236N; 1:67424310-67424310

 upper_aerodigestive_tract; larynxcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.146C>A; p.P49H; 1:67430155-67430155

 oesophaguscarcinoma; adenocarcinomaSubstitution - Missense

c.173C>T; p.A58V; 1:67430128-67430128

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.1175G>A; p.S392N; 1:67413259-67413259

 upper_aerodigestive_tract; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.1099C>T; p.R367C; 1:67415237-67415237

 prostateadenomaSubstitution - Missense

c.6T>C; p.P2P; 1:67430295-67430295

 stomachcarcinoma; adenocarcinomaSubstitution - coding silent

c.681C>T; p.V227V; 1:67424902-67424902

 urinary_tract; bladdercarcinomaSubstitution - coding silent

c.430G>T; p.E144*; 1:67426169-67426169

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - Nonsense

c.787G>A; p.E263K; 1:67424231-67424231

 lung; right_upper_lobecarcinoma; adenocarcinomaSubstitution - Missense

c.464+1G>T; p.?; 1:67426134-67426134

 stomachcarcinoma; adenocarcinomaUnknown

c.447C>T; p.G149G; 1:67426152-67426152

 skin; armmalignant_melanomaSubstitution - coding silent

c.410G>T; p.R137I; 1:67426189-67426189

 kidneyother; neoplasmSubstitution - Missense

c.1115G>A; p.G372E; 1:67415221-67415221

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.420G>A; p.K140K; 1:67426179-67426179

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - coding silent

c.1186C>G; p.P396A; 1:67413248-67413248

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.233G>T; p.R78L; 1:67430068-67430068

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.892A>G; p.N298D; 1:67420113-67420113

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.251C>T; p.P84L; 1:67430050-67430050

 skinmalignant_melanomaSubstitution - Missense