Cancer metastasis database

Annotation category 5

Gene information

Gene ID 259
Symbol

AMBP

Synonymous

A1M|EDC1|HCP|HI30|IATIL|ITI|ITIL|ITILC|UTI

Full name

alpha-1-microglobulin/bikunin precursor

Gene description

bikunin|complex-forming glycoprotein heterogeneous in charge|growth-inhibiting protein 19|inter-alpha-trypsin inhibitor light chain|protein AMBP|protein HC|trypstatin|uristatin|uronic-acid-rich protein

Cytoband

9q32-q33

Gene type

protein-coding

Synonymous

MIM:176870; HGNC:HGNC:453; Ensembl:ENSG00000106927; HPRD:01467; Vega:OTTHUMG00000020534

COSMIC somatic mutation

Mutation (CDS; AA; Chr)

Site

Histology

Mutation Type

c.438T>G; p.I146M; 9:114074052-114074052

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.75G>A; p.P25P; 9:114078135-114078135

 prostatecarcinoma; adenocarcinomaSubstitution - coding silent

c.75G>A; p.P25P; 9:114078135-114078135

 breastcarcinoma; ductal_carcinomaSubstitution - coding silent

c.75G>A; p.P25P; 9:114078135-114078135

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - coding silent

c.171G>T; p.K57N; 9:114076687-114076687

 ovarycarcinoma; serous_carcinomaSubstitution - Missense

c.465G>A; p.P155P; 9:114073016-114073016

 stomachcarcinoma; adenocarcinomaSubstitution - coding silent

c.1012G>A; p.G338S; 9:114060940-114060940

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.524C>T; p.P175L; 9:114072957-114072957

 skinmalignant_melanomaSubstitution - Missense

c.324C>T; p.L108L; 9:114074973-114074973

 skinmalignant_melanomaSubstitution - coding silent

c.969C>T; p.N323N; 9:114060983-114060983

 large_intestinecarcinoma; adenocarcinomaSubstitution - coding silent

c.561A>G; p.E187E; 9:114069741-114069741

 large_intestinecarcinoma; adenocarcinomaSubstitution - coding silent

c.879G>A; p.R293R; 9:114061073-114061073

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.76C>G; p.P26A; 9:114078134-114078134

 breastcarcinomaSubstitution - Missense

c.781T>C; p.Y261H; 9:114061496-114061496

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.403A>T; p.T135S; 9:114074087-114074087

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.782A>G; p.Y261C; 9:114061495-114061495

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.263A>C; p.K88T; 9:114075034-114075034

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.994G>A; p.E332K; 9:114060958-114060958

 skinmalignant_melanomaSubstitution - Missense

c.408G>A; p.K136K; 9:114074082-114074082

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.758C>T; p.S253F; 9:114061519-114061519

 skinmalignant_melanomaSubstitution - Missense

c.771G>A; p.E257E; 9:114061506-114061506

 breastcarcinomaSubstitution - coding silent

c.120C>A; p.I40I; 9:114076738-114076738

 endometriumcarcinoma; serous_carcinomaSubstitution - coding silent

c.49delG; p.V17fs*1; 9:114078161-114078161

 large_intestine; coloncarcinoma; adenocarcinomaDeletion - Frameshift

c.786C>T; p.G262G; 9:114061491-114061491

 breastcarcinomaSubstitution - coding silent

c.341G>T; p.W114L; 9:114074149-114074149

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.928G>A; p.G310R; 9:114061024-114061024

 skinmalignant_melanomaSubstitution - Missense

c.993G>T; p.K331N; 9:114060959-114060959

 skinmalignant_melanomaSubstitution - Missense

c.993G>T; p.K331N; 9:114060959-114060959

 skinmalignant_melanomaSubstitution - Missense

c.25T>C; p.L9L; 9:114078185-114078185

 skinmalignant_melanomaSubstitution - coding silent

c.88C>T; p.Q30*; 9:114078122-114078122

 oesophaguscarcinoma; squamous_cell_carcinomaSubstitution - Nonsense

c.131G>T; p.W44L; 9:114076727-114076727

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - Missense

c.116G>C; p.R39P; 9:114078094-114078094

 ovarycarcinoma; serous_carcinomaSubstitution - Missense

c.588G>A; p.E196E; 9:114069714-114069714

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.650G>A; p.G217D; 9:114062712-114062712

 lung; right_upper_lobecarcinoma; adenocarcinomaSubstitution - Missense

c.952G>A; p.G318R; 9:114061000-114061000

 skinmalignant_melanomaSubstitution - Missense

c.215A>G; p.E72G; 9:114076643-114076643

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.1050C>A; p.F350L; 9:114060248-114060248

 livercarcinoma; hepatocellular_carcinomaSubstitution - Missense

c.942C>A; p.L314L; 9:114061010-114061010

 pancreascarcinomaSubstitution - coding silent

c.834G>A; p.L278L; 9:114061443-114061443

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.1045C>T; p.R349C; 9:114060253-114060253

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.631G>T; p.E211*; 9:114062731-114062731

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - Nonsense

c.3G>C; p.M1I; 9:114078207-114078207

 breastcarcinomaSubstitution - Missense

c.36C>T; p.S12S; 9:114078174-114078174

 urinary_tract; bladdercarcinoma; transitional_cell_carcinomaSubstitution - coding silent

c.36C>T; p.S12S; 9:114078174-114078174

 urinary_tract; bladdercarcinomaSubstitution - coding silent

c.102C>T; p.N34N; 9:114078108-114078108

 stomachcarcinoma; adenocarcinomaSubstitution - coding silent

c.78C>T; p.P26P; 9:114078132-114078132

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.130T>G; p.W44G; 9:114076728-114076728

 thyroidcarcinomaSubstitution - Missense

c.477A>C; p.E159D; 9:114073004-114073004

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.346A>G; p.I116V; 9:114074144-114074144

 lung; right_upper_lobecarcinoma; adenocarcinomaSubstitution - Missense

c.1022G>C; p.G341A; 9:114060930-114060930

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - Missense

c.336C>A; p.S112S; 9:114074961-114074961

 central_nervous_system; brainprimitive_neuroectodermal_tumour-medulloblastomaSubstitution - coding silent

c.528G>A; p.E176E; 9:114072953-114072953

 skinmalignant_melanomaSubstitution - coding silent

c.590C>T; p.P197L; 9:114069712-114069712

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.954G>A; p.G318G; 9:114060998-114060998

 skin; upper_legmalignant_melanomaSubstitution - coding silent

c.72G>A; p.T24T; 9:114078138-114078138

 central_nervous_system; braingliomaSubstitution - coding silent

c.72G>A; p.T24T; 9:114078138-114078138

 urinary_tract; bladdercarcinomaSubstitution - coding silent

c.418C>T; p.R140C; 9:114074072-114074072

 prostatecarcinoma; adenocarcinomaSubstitution - Missense

c.231G>A; p.A77A; 9:114076627-114076627

 stomachcarcinoma; adenocarcinomaSubstitution - coding silent

c.685G>A; p.D229N; 9:114062677-114062677

 skinmalignant_melanomaSubstitution - Missense

c.333A>T; p.K111N; 9:114074964-114074964

 skinmalignant_melanomaSubstitution - Missense

c.603G>A; p.P201P; 9:114069699-114069699

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.16G>A; p.A6T; 9:114078194-114078194

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.16G>A; p.A6T; 9:114078194-114078194

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.16G>A; p.A6T; 9:114078194-114078194

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.408G>T; p.K136N; 9:114074082-114074082

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.205G>A; p.V69M; 9:114076653-114076653

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.71C>T; p.T24M; 9:114078139-114078139

 kidneycarcinoma; papillary_renal_cell_carcinomaSubstitution - Missense

c.952G>T; p.G318W; 9:114061000-114061000

 prostatecarcinoma; adenocarcinomaSubstitution - Missense

c.451T>C; p.Y151H; 9:114074039-114074039

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.31C>T; p.L11L; 9:114078179-114078179

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.717C>A; p.P239P; 9:114061560-114061560

 large_intestinecarcinoma; adenocarcinomaSubstitution - coding silent

c.717C>A; p.P239P; 9:114061560-114061560

 large_intestinecarcinoma; adenocarcinomaSubstitution - coding silent

c.809A>G; p.N270S; 9:114061468-114061468

 haematopoietic_and_lymphoid_tissuelymphoid_neoplasm; chronic_lymphocytic_leukaemia-small_lymphocytic_lymphomaSubstitution - Missense