Cancer metastasis database

Annotation category 5

Gene information

Gene ID 25794
Symbol

FSCN2

Synonymous

RFSN|RP30

Full name

fascin actin-bundling protein 2, retinal

Gene description

fascin homolog 2, actin-bundling protein, retinal|fascin-2

Cytoband

17q25

Gene type

protein-coding

Synonymous

MIM:607643; HGNC:HGNC:3960; Ensembl:ENSG00000186765; HPRD:06366; Vega:OTTHUMG00000167477

COSMIC somatic mutation

Mutation (CDS; AA; Chr)

Site

Histology

Mutation Type

c.867C>T; p.H289H; 17:81535092-81535092

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.915delC; p.Y306fs*38; 17:81535140-81535140

 endometriumcarcinoma; endometrioid_carcinomaDeletion - Frameshift

c.935A>G; p.Y312C; 17:81535160-81535160

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.794C>T; p.A265V; 17:81529325-81529325

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.416C>A; p.P139Q; 17:81528947-81528947

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.547C>G; p.R183G; 17:81529078-81529078

 urinary_tract; bladdercarcinomaSubstitution - Missense

c.55G>A; p.D19N; 17:81528586-81528586

 bone; extraskeletalEwings_sarcoma-peripheral_primitive_neuroectodermal_tumourSubstitution - Missense

c.629A>G; p.Y210C; 17:81529160-81529160

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.568G>C; p.D190H; 17:81529099-81529099

 breastcarcinomaSubstitution - Missense

c.333C>T; p.F111F; 17:81528864-81528864

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.279G>A; p.L93L; 17:81528810-81528810

 stomachcarcinoma; adenocarcinomaSubstitution - coding silent

c.318G>A; p.P106P; 17:81528849-81528849

 breastcarcinomaSubstitution - coding silent

c.1035C>G; p.L345L; 17:81536197-81536197

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.781G>T; p.V261L; 17:81529312-81529312

 prostatecarcinoma; adenocarcinomaSubstitution - Missense

c.822G>A; p.R274R; 17:81529353-81529353

 kidneycarcinoma; papillary_renal_cell_carcinomaSubstitution - coding silent

c.48C>T; p.L16L; 17:81528579-81528579

 ovarycarcinoma; serous_carcinomaSubstitution - coding silent

c.96G>T; p.K32N; 17:81528627-81528627

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.1317C>T; p.S439S; 17:81536761-81536761

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - coding silent

c.1217C>A; p.P406H; 17:81536661-81536661

 livercarcinoma; hepatocellular_carcinomaSubstitution - Missense

c.157G>A; p.G53R; 17:81528688-81528688

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.1362C>A; p.F454L; 17:81536891-81536891

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.142C>A; p.L48M; 17:81528673-81528673

 livercarcinoma; hepatocellular_carcinomaSubstitution - Missense

c.1134G>A; p.G378G; 17:81536578-81536578

 skinmalignant_melanomaSubstitution - coding silent

c.377C>T; p.S126F; 17:81528908-81528908

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.402C>T; p.H134H; 17:81528933-81528933

 skinmalignant_melanomaSubstitution - coding silent

c.778C>T; p.Q260*; 17:81529309-81529309

 large_intestinecarcinoma; adenocarcinomaSubstitution - Nonsense

c.281C>T; p.P94L; 17:81528812-81528812

 skinmalignant_melanomaSubstitution - Missense

c.1200C>G; p.L400L; 17:81536644-81536644

 urinary_tract; bladdercarcinomaSubstitution - coding silent

c.12C>T; p.N4N; 17:81528543-81528543

 autonomic_ganglianeuroblastomaSubstitution - coding silent

c.734G>A; p.R245Q; 17:81529265-81529265

 skinmalignant_melanomaSubstitution - Missense

c.1351G>T; p.D451Y; 17:81536880-81536880

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.1411G>C; p.E471Q; 17:81536940-81536940

 urinary_tract; bladdercarcinomaSubstitution - Missense

c.1169C>G; p.S390C; 17:81536613-81536613

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.354G>C; p.L118L; 17:81528885-81528885

 livercarcinomaSubstitution - coding silent

c.341C>T; p.T114I; 17:81528872-81528872

 skinmalignant_melanomaSubstitution - Missense

c.596G>A; p.R199H; 17:81529127-81529127

 upper_aerodigestive_tract; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.567T>C; p.C189C; 17:81529098-81529098

 breastcarcinomaSubstitution - coding silent

c.19C>A; p.H7N; 17:81528550-81528550

 oesophagus; lower_thirdcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.1431C>T; p.F477F; 17:81536960-81536960

 oesophaguscarcinoma; adenocarcinomaSubstitution - coding silent

c.1400G>C; p.G467A; 17:81536929-81536929

 pancreascarcinomaSubstitution - Missense

c.65G>A; p.R22H; 17:81528596-81528596

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.1262G>A; p.R421H; 17:81536706-81536706

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.525C>T; p.L175L; 17:81529056-81529056

 large_intestinecarcinoma; adenocarcinomaSubstitution - coding silent

c.1399G>C; p.G467R; 17:81536928-81536928

 pancreascarcinomaSubstitution - Missense

c.1022G>A; p.R341Q; 17:81536184-81536184

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - Missense

c.879G>T; p.L293L; 17:81535104-81535104

 kidneyother; neoplasmSubstitution - coding silent

c.583C>T; p.R195C; 17:81529114-81529114

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.567_568TG>CC; p.D190H; 17:81529098-81529099

 breastcarcinomaSubstitution - Missense

c.45C>T; p.G15G; 17:81528576-81528576

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - coding silent

c.33G>T; p.K11N; 17:81528564-81528564

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.438G>A; p.V146V; 17:81528969-81528969

 lungcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.702C>A; p.P234P; 17:81529233-81529233

 lungcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.193C>A; p.L65M; 17:81528724-81528724

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense