| Gene ID | 252969 |
| Symbol | NEIL2 |
| Synonymous | NEH2|NEI2 |
| Full name | nei endonuclease VIII-like 2 (E. coli) |
| Gene description | DNA glycosylase/AP lyase Neil2|DNA-(apurinic or apyrimidinic site) lyase Neil2|endonuclease 8-like 2|endonuclease VIII-like 2|nei homolog 2|nei like 2|nei-like protein 2 |
| Cytoband | 8p23.1 |
| Gene type | protein-coding |
| Synonymous | MIM:608933; HGNC:HGNC:18956; Ensembl:ENSG00000154328; HPRD:16406; Vega:OTTHUMG00000090753 |
Mutation (CDS; AA; Chr) | Site | Histology | Mutation Type |
|---|---|---|---|
c.138G>T; p.Q46H; 8:11771585-11771585 |
large_intestine; colon | carcinoma; adenocarcinoma | Substitution - Missense |
c.859C>T; p.Q287*; 8:11786133-11786133 |
stomach | carcinoma; adenocarcinoma | Substitution - Nonsense |
c.422T>C; p.V141A; 8:11779881-11779881 |
pancreas | carcinoma | Substitution - Missense |
c.422T>C; p.V141A; 8:11779881-11779881 |
pancreas | carcinoma | Substitution - Missense |
c.770G>T; p.R257L; 8:11786044-11786044 |
haematopoietic_and_lymphoid_tissue | haematopoietic_neoplasm; acute_myeloid_leukaemia | Substitution - Missense |
c.240G>A; p.K80K; 8:11779699-11779699 |
stomach | carcinoma; adenocarcinoma | Substitution - coding silent |
c.433G>A; p.D145N; 8:11779892-11779892 |
endometrium | carcinoma; endometrioid_carcinoma | Substitution - Missense |
c.874C>A; p.P292T; 8:11786148-11786148 |
large_intestine; colon | carcinoma; adenocarcinoma | Substitution - Missense |
c.878C>T; p.A293V; 8:11786152-11786152 |
stomach | carcinoma; adenocarcinoma | Substitution - Missense |
c.491G>C; p.R164T; 8:11779950-11779950 |
bone | Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour | Substitution - Missense |
c.364G>A; p.A122T; 8:11779823-11779823 |
large_intestine; colon | carcinoma; adenocarcinoma | Substitution - Missense |
c.821G>A; p.G274D; 8:11786095-11786095 |
central_nervous_system; brain | glioma; astrocytoma_Grade_IV | Substitution - Missense |
c.401G>A; p.S134N; 8:11779860-11779860 |
stomach | carcinoma; intestinal_adenocarcinoma | Substitution - Missense |
c.367C>T; p.P123S; 8:11779826-11779826 |
skin | malignant_melanoma | Substitution - Missense |
c.688G>T; p.G230W; 8:11783399-11783399 |
lung; right_upper_lobe | carcinoma; adenocarcinoma | Substitution - Missense |
c.321C>T; p.L107L; 8:11779780-11779780 |
skin | malignant_melanoma | Substitution - coding silent |
c.321C>T; p.L107L; 8:11779780-11779780 |
large_intestine; colon | carcinoma; adenocarcinoma | Substitution - coding silent |
c.860A>T; p.Q287L; 8:11786134-11786134 |
lung; right_upper_lobe | carcinoma; adenocarcinoma | Substitution - Missense |
c.253G>T; p.D85Y; 8:11779712-11779712 |
large_intestine; colon | carcinoma; adenocarcinoma | Substitution - Missense |
c.31C>T; p.H11Y; 8:11771478-11771478 |
endometrium | carcinoma; endometrioid_carcinoma | Substitution - Missense |
c.526G>A; p.A176T; 8:11783237-11783237 |
large_intestine; colon | carcinoma; adenocarcinoma | Substitution - Missense |
c.525G>T; p.L175L; 8:11783236-11783236 |
lung | carcinoma; squamous_cell_carcinoma | Substitution - coding silent |
c.913G>A; p.E305K; 8:11786187-11786187 |
stomach | carcinoma; adenocarcinoma | Substitution - Missense |
c.376G>C; p.D126H; 8:11779835-11779835 |
urinary_tract; bladder | carcinoma | Substitution - Missense |
c.651C>T; p.C217C; 8:11783362-11783362 |
large_intestine; colon | carcinoma; adenocarcinoma | Substitution - coding silent |
c.355G>T; p.E119*; 8:11779814-11779814 |
lung | carcinoma; squamous_cell_carcinoma | Substitution - Nonsense |
c.931C>G; p.L311V; 8:11786205-11786205 |
bone | Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour | Substitution - Missense |
c.903G>A; p.A301A; 8:11786177-11786177 |
upper_aerodigestive_tract; mouth | carcinoma; squamous_cell_carcinoma | Substitution - coding silent |
c.251C>T; p.A84V; 8:11779710-11779710 |
large_intestine; rectum | carcinoma; adenocarcinoma | Substitution - Missense |
c.251C>T; p.A84V; 8:11779710-11779710 |
stomach | carcinoma; adenocarcinoma | Substitution - Missense |
c.72G>A; p.K24K; 8:11771519-11771519 |
skin | malignant_melanoma | Substitution - coding silent |
c.282G>A; p.G94G; 8:11779741-11779741 |
stomach | carcinoma; adenocarcinoma | Substitution - coding silent |
c.688+1G>A; p.?; 8:11783400-11783400 |
skin | malignant_melanoma | Unknown |
c.804T>C; p.S268S; 8:11786078-11786078 |
stomach | carcinoma; adenocarcinoma | Substitution - coding silent |
c.581G>A; p.C194Y; 8:11783292-11783292 |
lung | carcinoma; small_cell_carcinoma | Substitution - Missense |
c.209C>T; p.T70I; 8:11779668-11779668 |
kidney | carcinoma; clear_cell_renal_cell_carcinoma | Substitution - Missense |
c.72G>C; p.K24N; 8:11771519-11771519 |
skin; head_neck | carcinoma; squamous_cell_carcinoma | Substitution - Missense |
c.363C>T; p.D121D; 8:11779822-11779822 |
endometrium | carcinoma; endometrioid_carcinoma | Substitution - coding silent |
c.363C>T; p.D121D; 8:11779822-11779822 |
stomach | carcinoma; adenocarcinoma | Substitution - coding silent |
c.384G>A; p.G128G; 8:11779843-11779843 |
skin; head_neck | carcinoma; squamous_cell_carcinoma | Substitution - coding silent |
c.15G>A; p.P5P; 8:11771462-11771462 |
lung; right_upper_lobe | carcinoma; adenocarcinoma | Substitution - coding silent |
c.479A>G; p.D160G; 8:11779938-11779938 |
large_intestine; rectum | carcinoma; adenocarcinoma | Substitution - Missense |
c.972G>A; p.E324E; 8:11786246-11786246 |
large_intestine; colon | carcinoma; adenocarcinoma | Substitution - coding silent |