lung cancer gene and literature database Home

Annotation category 5

Basic annotation
Ontology and pathways
Literature evidence
Curated literatures
Expression
Gene expression chart
Somatic mutation
COSMIC and TCGA mutations
Network
Gene interaction
ceRNA
Gene-related ceRNA

Gene information

Gene ID	2528
Symbol	FUT6
Synonymous	FCT3A\|FT1A\|Fuc-TVI\|FucT-VI
Full name	fucosyltransferase 6 (alpha (1,3) fucosyltransferase)
Gene description	alpha-(1,3)-fucosyltransferase 6\|fucosyltransferase VI\|galactoside 3-L-fucosyltransferase
Cytoband	19p13.3
Gene type	protein-coding
Synonymous	MIM:136836; HGNC:HGNC:4017; Ensembl:ENSG00000156413; HPRD:00651; Vega:OTTHUMG00000167335

COSMIC somatic mutation

Mutation (CDS; AA; Chr)	Site	Histology	Mutation Type
c.1058G>A; p.G353D; 19:5831510-5831510	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.647T>A; p.L216H; 19:5831921-5831921	liver	carcinoma	Substitution - Missense
c.647T>A; p.L216H; 19:5831921-5831921	liver	carcinoma	Substitution - Missense
c.407T>C; p.M136T; 19:5832161-5832161	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.682C>A; p.L228M; 19:5831886-5831886	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.458A>G; p.N153S; 19:5832110-5832110	breast	carcinoma	Substitution - Missense
c.184C>T; p.P62S; 19:5832384-5832384	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.121C>T; p.P41S; 19:5832447-5832447	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.855A>G; p.P285P; 19:5831713-5831713	liver	carcinoma; hepatocellular_carcinoma	Substitution - coding silent
c.700A>T; p.M234L; 19:5831868-5831868	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.965G>A; p.R322Q; 19:5831603-5831603	skin	malignant_melanoma	Substitution - Missense
c.667C>T; p.R223C; 19:5831901-5831901	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.280G>A; p.A94T; 19:5832288-5832288	pancreas	carcinoma	Substitution - Missense
c.1046A>G; p.Y349C; 19:5831522-5831522	oesophagus; lower_third	carcinoma; adenocarcinoma	Substitution - Missense
c.342C>G; p.Y114*; 19:5832226-5832226	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Nonsense
c.49C>A; p.L17M; 19:5832519-5832519	kidney	carcinoma; papillary_renal_cell_carcinoma	Substitution - Missense
c.175C>G; p.H59D; 19:5832393-5832393	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.172G>A; p.A58T; 19:5832396-5832396	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.213T>A; p.F71L; 19:5832355-5832355	skin	malignant_melanoma	Substitution - Missense
c.399G>T; p.W133C; 19:5832169-5832169	urinary_tract; bladder	carcinoma; transitional_cell_carcinoma	Substitution - Missense
c.480C>A; p.S160R; 19:5832088-5832088	bone; tibia	Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	Substitution - Missense
c.224T>C; p.I75T; 19:5832344-5832344	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.517C>T; p.P173S; 19:5832051-5832051	liver	carcinoma	Substitution - Missense
c.517C>T; p.P173S; 19:5832051-5832051	liver	carcinoma	Substitution - Missense
c.439G>C; p.A147P; 19:5832129-5832129	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.324C>G; p.H108Q; 19:5832244-5832244	breast	carcinoma	Substitution - Missense
c.810C>T; p.P270P; 19:5831758-5831758	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.371C>T; p.P124L; 19:5832197-5832197	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.670T>C; p.S224P; 19:5831898-5831898	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.1004C>A; p.A335D; 19:5831564-5831564	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.617T>G; p.V206G; 19:5831951-5831951	breast	carcinoma	Substitution - Missense
c.913C>A; p.L305M; 19:5831655-5831655	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.58C>G; p.L20V; 19:5832510-5832510	salivary_gland	carcinoma; adenoid_cystic_carcinoma	Substitution - Missense
c.691G>A; p.G231R; 19:5831877-5831877	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.412T>C; p.S138P; 19:5832156-5832156	urinary_tract; bladder	carcinoma	Substitution - Missense
c.907C>G; p.R303G; 19:5831661-5831661	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.907C>G; p.R303G; 19:5831661-5831661	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.907C>G; p.R303G; 19:5831661-5831661	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.907C>G; p.R303G; 19:5831661-5831661	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.741G>T; p.E247D; 19:5831827-5831827	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.262G>A; p.A88T; 19:5832306-5832306	thyroid	carcinoma; anaplastic_carcinoma	Substitution - Missense
c.388C>T; p.R130*; 19:5832180-5832180	breast	carcinoma	Substitution - Nonsense
c.1026A>G; p.K342K; 19:5831542-5831542	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.398G>T; p.W133L; 19:5832170-5832170	urinary_tract; bladder	carcinoma; transitional_cell_carcinoma	Substitution - Missense
c.982C>T; p.R328C; 19:5831586-5831586	skin	malignant_melanoma	Substitution - Missense
c.86G>A; p.C29Y; 19:5832482-5832482	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.628C>T; p.Q210*; 19:5831940-5831940	skin	malignant_melanoma	Substitution - Nonsense
c.1003G>A; p.A335T; 19:5831565-5831565	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.189G>A; p.L63L; 19:5832379-5832379	oesophagus	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.771G>T; p.E257D; 19:5831797-5831797	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.252G>A; p.V84V; 19:5832316-5832316	oesophagus; middle_third	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.17C>T; p.P6L; 19:5832551-5832551	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.17C>T; p.P6L; 19:5832551-5832551	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.353C>A; p.A118D; 19:5832215-5832215	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.376C>T; p.R126W; 19:5832192-5832192	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.716G>C; p.R239P; 19:5831852-5831852	kidney	other; neoplasm	Substitution - Missense
c.376C>T; p.R126W; 19:5832192-5832192	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.476G>A; p.R159H; 19:5832092-5832092	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.962G>A; p.W321*; 19:5831606-5831606	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Nonsense
c.204G>A; p.T68T; 19:5832364-5832364	bone; tibia	Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	Substitution - coding silent
c.739G>A; p.E247K; 19:5831829-5831829	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.236G>A; p.R79H; 19:5832332-5832332	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.945C>A; p.Y315*; 19:5831623-5831623	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Nonsense
c.206G>A; p.W69*; 19:5832362-5832362	skin	malignant_melanoma	Substitution - Nonsense
c.786C>T; p.N262N; 19:5831782-5831782	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.406A>G; p.M136V; 19:5832162-5832162	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense

Annotation category 5

Basic annotation

Literature evidence

Expression

Somatic mutation

Network

ceRNA

Gene information

COSMIC somatic mutation