lung cancer gene and literature database Home

Annotation category 5

Basic annotation
Ontology and pathways
Literature evidence
Curated literatures
Expression
Gene expression chart
Somatic mutation
COSMIC and TCGA mutations
Network
Gene interaction
ceRNA
Gene-related ceRNA

Gene information

Gene ID	2525
Symbol	FUT3
Synonymous	CD174\|FT3B\|FucT-III\|LE\|Les
Full name	fucosyltransferase 3 (galactoside 3(4)-L-fucosyltransferase, Lewis blood group)
Gene description	Lewis FT\|alpha-(1,3/1,4)-fucosyltransferase\|blood group Lewis alpha-4-fucosyltransferase\|fucosyltransferase III\|galactoside 3(4)-L-fucosyltransferase
Cytoband	19p13.3
Gene type	protein-coding
Synonymous	MIM:111100; HGNC:HGNC:4014; Ensembl:ENSG00000171124; HPRD:00196; Vega:OTTHUMG00000180614

COSMIC somatic mutation

Mutation (CDS; AA; Chr)	Site	Histology	Mutation Type
c.380C>T; p.P127L; 19:5844460-5844460	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.940G>A; p.A314T; 19:5843900-5843900	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.391C>T; p.R131C; 19:5844449-5844449	breast	carcinoma	Substitution - Missense
c.710C>T; p.T237M; 19:5844130-5844130	breast	carcinoma	Substitution - Missense
c.710C>T; p.T237M; 19:5844130-5844130	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.570C>T; p.T190T; 19:5844270-5844270	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.71T>C; p.L24P; 19:5844769-5844769	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.259G>T; p.G87C; 19:5844581-5844581	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.202C>T; p.R68W; 19:5844638-5844638	liver	carcinoma; hepatocellular_carcinoma	Substitution - Missense
c.202C>T; p.R68W; 19:5844638-5844638	liver	carcinoma; hepatocellular_carcinoma	Substitution - Missense
c.202C>T; p.R68W; 19:5844638-5844638	thyroid	other; neoplasm	Substitution - Missense
c.202C>T; p.R68W; 19:5844638-5844638	thyroid	other; neoplasm	Substitution - Missense
c.190C>T; p.L64L; 19:5844650-5844650	skin	malignant_melanoma	Substitution - coding silent
c.141T>C; p.A47A; 19:5844699-5844699	ovary	other; neoplasm	Substitution - coding silent
c.141T>C; p.A47A; 19:5844699-5844699	ovary	other; neoplasm	Substitution - coding silent
c.268G>A; p.D90N; 19:5844572-5844572	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.844G>A; p.E282K; 19:5843996-5843996	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.1029A>G; p.K343K; 19:5843811-5843811	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - coding silent
c.1029A>G; p.K343K; 19:5843811-5843811	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	Substitution - coding silent
c.1083C>T; p.T361T; 19:5843757-5843757	skin	malignant_melanoma	Substitution - coding silent
c.230C>A; p.A77D; 19:5844610-5844610	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.459C>T; p.F153F; 19:5844381-5844381	skin	malignant_melanoma	Substitution - coding silent
c.379C>T; p.P127S; 19:5844461-5844461	skin	malignant_melanoma	Substitution - Missense
c.961C>T; p.R321C; 19:5843879-5843879	skin	malignant_melanoma	Substitution - Missense
c.359G>A; p.R120H; 19:5844481-5844481	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.571G>A; p.E191K; 19:5844269-5844269	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.571G>A; p.E191K; 19:5844269-5844269	skin	malignant_melanoma	Substitution - Missense
c.571G>A; p.E191K; 19:5844269-5844269	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.253G>C; p.V85L; 19:5844587-5844587	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.127G>T; p.G43*; 19:5844713-5844713	thyroid	carcinoma	Substitution - Nonsense
c.314T>C; p.M105T; 19:5844526-5844526	thyroid	other; neoplasm	Substitution - Missense
c.314T>C; p.M105T; 19:5844526-5844526	thyroid	other; neoplasm	Substitution - Missense
c.742G>A; p.E248K; 19:5844098-5844098	cervix	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.19_21delGCC; p.A7delA; 19:5844819-5844821	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Deletion - In frame
c.1083C>A; p.T361T; 19:5843757-5843757	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.790G>A; p.A264T; 19:5844050-5844050	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.182C>T; p.P61L; 19:5844658-5844658	kidney	other; neoplasm	Substitution - Missense
c.182C>T; p.P61L; 19:5844658-5844658	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.391C>G; p.R131G; 19:5844449-5844449	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.167C>T; p.T56I; 19:5844673-5844673	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.257C>T; p.P86L; 19:5844583-5844583	skin	malignant_melanoma	Substitution - Missense
c.374C>T; p.P125L; 19:5844466-5844466	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.587C>T; p.A196V; 19:5844253-5844253	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.651C>T; p.L217L; 19:5844189-5844189	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - coding silent
c.347A>G; p.N116S; 19:5844493-5844493	skin	malignant_melanoma	Substitution - Missense
c.199C>A; p.L67I; 19:5844641-5844641	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.178C>T; p.R60C; 19:5844662-5844662	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.157C>T; p.R53*; 19:5844683-5844683	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Nonsense
c.152C>A; p.S51Y; 19:5844688-5844688	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.856C>T; p.P286S; 19:5843984-5843984	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.657G>T; p.V219V; 19:5844183-5844183	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.179G>C; p.R60P; 19:5844661-5844661	prostate	carcinoma; adenocarcinoma	Substitution - Missense
c.179G>C; p.R60P; 19:5844661-5844661	breast	carcinoma	Substitution - Missense
c.451A>G; p.R151G; 19:5844389-5844389	thyroid	carcinoma	Substitution - Missense
c.778C>A; p.L260M; 19:5844062-5844062	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.943C>A; p.R315S; 19:5843897-5843897	breast	carcinoma	Substitution - Missense
c.16G>A; p.A6T; 19:5844824-5844824	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.392G>A; p.R131H; 19:5844448-5844448	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.59T>G; p.L20R; 19:5844781-5844781	breast	carcinoma	Substitution - Missense
c.209G>A; p.W70*; 19:5844631-5844631	skin	malignant_melanoma	Substitution - Nonsense
c.134delC; p.P45fs*20; 19:5844706-5844706	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.223C>T; p.P75S; 19:5844617-5844617	skin	malignant_melanoma	Substitution - Missense
c.1036C>G; p.Q346E; 19:5843804-5843804	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.203G>T; p.R68L; 19:5844637-5844637	skin	malignant_melanoma	Substitution - Missense
c.596A>T; p.N199I; 19:5844244-5844244	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.517G>A; p.E173K; 19:5844323-5844323	urinary_tract; bladder	carcinoma	Substitution - Missense
c.1067T>A; p.I356K; 19:5843773-5843773	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.195C>G; p.I65M; 19:5844645-5844645	upper_aerodigestive_tract; larynx	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.113G>A; p.R38Q; 19:5844727-5844727	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.267C>T; p.A89A; 19:5844573-5844573	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.1044C>T; p.S348S; 19:5843796-5843796	skin	malignant_melanoma	Substitution - coding silent
c.1041A>G; p.E347E; 19:5843799-5843799	oesophagus	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.623G>A; p.R208H; 19:5844217-5844217	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.698C>T; p.T233I; 19:5844142-5844142	skin	malignant_melanoma	Substitution - Missense

Annotation category 5

Basic annotation

Literature evidence

Expression

Somatic mutation

Network

ceRNA

Gene information

COSMIC somatic mutation