Cancer metastasis database

Annotation category 5

Gene information

Gene ID 2520
Symbol

GAST

Synonymous

GAS

Full name

gastrin

Gene description

preprogastrin

Cytoband

17q21

Gene type

protein-coding

Synonymous

MIM:137250; HGNC:HGNC:4164; Ensembl:ENSG00000184502; HPRD:00671; Vega:OTTHUMG00000133496

COSMIC somatic mutation

Mutation (CDS; AA; Chr)

Site

Histology

Mutation Type

c.277G>A; p.G93S; 17:41715843-41715843

stomachcarcinoma; diffuse_adenocarcinomaSubstitution - Missense

c.284G>A; p.R95H; 17:41715850-41715850

large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - Missense

c.242A>G; p.E81G; 17:41715808-41715808

thyroidother; neoplasmSubstitution - Missense

c.300G>T; p.E100D; 17:41715866-41715866

endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.22G>A; p.V8M; 17:41715458-41715458

stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.229G>A; p.G77R; 17:41715795-41715795

skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.229G>A; p.G77R; 17:41715795-41715795

skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.54C>A; p.F18L; 17:41715490-41715490

large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.264A>G; p.G88G; 17:41715830-41715830

large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - coding silent

c.118A>G; p.R40G; 17:41715554-41715554

stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.7C>T; p.R3*; 17:41715443-41715443

prostatecarcinoma; adenocarcinomaSubstitution - Nonsense

c.276C>T; p.F92F; 17:41715842-41715842

large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - coding silent

c.82C>T; p.Q28*; 17:41715518-41715518

lungcarcinoma; small_cell_carcinomaSubstitution - Nonsense

c.23T>C; p.V8A; 17:41715459-41715459

breastcarcinomaSubstitution - Missense

c.111G>T; p.G37G; 17:41715547-41715547

lungcarcinoma; adenocarcinomaSubstitution - coding silent

c.161C>G; p.S54C; 17:41715597-41715597

oesophagus; middle_thirdcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.120G>A; p.R40R; 17:41715556-41715556

skinmalignant_melanomaSubstitution - coding silent

c.47C>T; p.A16V; 17:41715483-41715483

endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.283C>A; p.R95S; 17:41715849-41715849

kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - Missense

c.77G>A; p.R26H; 17:41715513-41715513

large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.289G>A; p.A97T; 17:41715855-41715855

livercarcinomaSubstitution - Missense

c.281G>A; p.R94H; 17:41715847-41715847

large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.115A>G; p.N39D; 17:41715551-41715551

endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.169C>T; p.R57*; 17:41715605-41715605

large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Nonsense

c.225G>A; p.K75K; 17:41715791-41715791

skinmalignant_melanomaSubstitution - coding silent

c.169C>T; p.R57*; 17:41715605-41715605

endometriumcarcinoma; endometrioid_carcinomaSubstitution - Nonsense

c.178C>G; p.L60V; 17:41715614-41715614

pancreascarcinoma; acinar_carcinomaSubstitution - Missense

c.110G>A; p.G37E; 17:41715546-41715546

central_nervous_system; braingliomaSubstitution - Missense

c.219C>T; p.S73S; 17:41715785-41715785

skinmalignant_melanomaSubstitution - coding silent