lung cancer gene and literature database Home

Annotation category 5

Basic annotation
Ontology and pathways
Literature evidence
Curated literatures
Expression
Gene expression chart
Somatic mutation
COSMIC and TCGA mutations
Network
Gene interaction
ceRNA
Gene-related ceRNA

Gene information

Gene ID	23650
Symbol	TRIM29
Synonymous	ATDC
Full name	tripartite motif containing 29
Gene description	ataxia telangiectasia group D-associated protein\|ataxia-telangiectasia group D-associated protein\|tripartite motif protein TRIM29\|tripartite motif-containing 29\|tripartite motif-containing protein 29
Cytoband	11q23.3
Gene type	protein-coding
Synonymous	MIM:610658; HGNC:HGNC:17274; Ensembl:ENSG00000137699; HPRD:10280; Vega:OTTHUMG00000140377

COSMIC somatic mutation

Mutation (CDS; AA; Chr)	Site	Histology	Mutation Type
c.663G>T; p.E221D; 11:120137369-120137369	liver	carcinoma; hepatocellular_carcinoma	Substitution - Missense
c.663G>T; p.E221D; 11:120137369-120137369	liver	carcinoma	Substitution - Missense
c.72C>A; p.G24G; 11:120137960-120137960	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.1674G>T; p.Q558H; 11:120115368-120115368	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.602C>T; p.P201L; 11:120137430-120137430	skin	malignant_melanoma	Substitution - Missense
c.602C>T; p.P201L; 11:120137430-120137430	prostate	carcinoma; adenocarcinoma	Substitution - Missense
c.436G>A; p.G146R; 11:120137596-120137596	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1761C>A; p.A587A; 11:120112420-120112420	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - coding silent
c.170G>A; p.G57D; 11:120137862-120137862	skin	malignant_melanoma	Substitution - Missense
c.1646G>A; p.R549Q; 11:120115396-120115396	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1500G>T; p.K500N; 11:120120601-120120601	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1401C>T; p.T467T; 11:120122988-120122988	skin	malignant_melanoma	Substitution - coding silent
c.353C>A; p.P118H; 11:120137679-120137679	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1444C>T; p.R482W; 11:120120657-120120657	skin	malignant_melanoma	Substitution - Missense
c.353C>A; p.P118H; 11:120137679-120137679	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.406C>A; p.R136R; 11:120137626-120137626	prostate	carcinoma; adenocarcinoma	Substitution - coding silent
c.704T>G; p.F235C; 11:120137328-120137328	breast	carcinoma	Substitution - Missense
c.1394C>T; p.P465L; 11:120122995-120122995	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1394C>T; p.P465L; 11:120122995-120122995	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.17C>A; p.A6D; 11:120138015-120138015	upper_aerodigestive_tract; mouth	carcinoma	Substitution - Missense
c.592C>T; p.H198Y; 11:120137440-120137440	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.17C>A; p.A6D; 11:120138015-120138015	upper_aerodigestive_tract; mouth	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.519C>T; p.C173C; 11:120137513-120137513	prostate	carcinoma; adenocarcinoma	Substitution - coding silent
c.1697C>A; p.T566N; 11:120115345-120115345	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1429C>T; p.P477S; 11:120122960-120122960	skin; arm	malignant_melanoma	Substitution - Missense
c.1171C>T; p.P391S; 11:120125853-120125853	skin	malignant_melanoma	Substitution - Missense
c.502T>C; p.S168P; 11:120137530-120137530	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1631A>G; p.Y544C; 11:120115411-120115411	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.370A>T; p.K124*; 11:120137662-120137662	skin	malignant_melanoma	Substitution - Nonsense
c.993G>A; p.A331A; 11:120127477-120127477	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.893G>A; p.R298H; 11:120128407-120128407	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.261C>G; p.D87E; 11:120137771-120137771	ovary	carcinoma	Substitution - Missense
c.668G>A; p.R223H; 11:120137364-120137364	liver	carcinoma	Substitution - Missense
c.586G>A; p.E196K; 11:120137446-120137446	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1670C>T; p.P557L; 11:120115372-120115372	skin	malignant_melanoma	Substitution - Missense
c.1270G>T; p.V424F; 11:120125754-120125754	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1045_1046insGATG; p.A349fs*5; 11:120127424-120127425	liver	carcinoma; hepatocellular_carcinoma	Insertion - Frameshift
c.714C>G; p.T238T; 11:120137318-120137318	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.1541C>T; p.S514F; 11:120118309-120118309	breast	carcinoma; ductal_carcinoma	Substitution - Missense
c.260A>C; p.D87A; 11:120137772-120137772	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1594G>A; p.V532I; 11:120118256-120118256	stomach	carcinoma; intestinal_adenocarcinoma	Substitution - Missense
c.1638C>T; p.S546S; 11:120115404-120115404	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; acute_lymphoblastic_B_cell_leukaemia	Substitution - coding silent
c.390C>T; p.S130S; 11:120137642-120137642	skin	malignant_melanoma	Substitution - coding silent
c.469G>A; p.D157N; 11:120137563-120137563	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.469G>A; p.D157N; 11:120137563-120137563	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.1090C>A; p.R364R; 11:120127380-120127380	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.1497G>A; p.Q499Q; 11:120120604-120120604	skin	malignant_melanoma	Substitution - coding silent
c.1596C>T; p.V532V; 11:120118254-120118254	oesophagus; lower_third	carcinoma; adenocarcinoma	Substitution - coding silent
c.666C>T; p.A222A; 11:120137366-120137366	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.616G>A; p.A206T; 11:120137416-120137416	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.931G>A; p.E311K; 11:120127539-120127539	skin	malignant_melanoma	Substitution - Missense
c.384C>G; p.R128R; 11:120137648-120137648	urinary_tract; bladder	carcinoma	Substitution - coding silent
c.957G>T; p.R319R; 11:120127513-120127513	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - coding silent
c.580T>A; p.F194I; 11:120137452-120137452	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; chronic_lymphocytic_leukaemia-small_lymphocytic_lymphoma	Substitution - Missense
c.580T>A; p.F194I; 11:120137452-120137452	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; chronic_lymphocytic_leukaemia-small_lymphocytic_lymphoma	Substitution - Missense
c.736C>T; p.L246F; 11:120137296-120137296	skin	malignant_melanoma	Substitution - Missense
c.351A>T; p.P117P; 11:120137681-120137681	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - coding silent
c.693G>A; p.T231T; 11:120137339-120137339	skin	malignant_melanoma	Substitution - coding silent
c.1647G>A; p.R549R; 11:120115395-120115395	skin	malignant_melanoma	Substitution - coding silent
c.1395G>A; p.P465P; 11:120122994-120122994	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.1534T>C; p.Y512H; 11:120118316-120118316	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1534T>C; p.Y512H; 11:120118316-120118316	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.120C>T; p.A40A; 11:120137912-120137912	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.467C>T; p.A156V; 11:120137565-120137565	skin	malignant_melanoma	Substitution - Missense
c.229C>T; p.R77*; 11:120137803-120137803	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; acute_lymphoblastic_leukaemia	Substitution - Nonsense
c.992C>T; p.A331V; 11:120127478-120127478	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.707G>A; p.C236Y; 11:120137325-120137325	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.1365G>A; p.T455T; 11:120123024-120123024	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.1365G>A; p.T455T; 11:120123024-120123024	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - coding silent
c.546_547GG>TT; p.K182_A183>11:120137485-120137486	lung	carcinoma; adenocarcinoma	Complex - compound substitution
c.1162T>A; p.S388T; 11:120125862-120125862	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.190G>A; p.E64K; 11:120137842-120137842	skin	malignant_melanoma	Substitution - Missense
c.1474C>T; p.R492C; 11:120120627-120120627	pancreas	carcinoma	Substitution - Missense
c.398C>T; p.S133L; 11:120137634-120137634	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1693C>A; p.Q565K; 11:120115349-120115349	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.1312G>A; p.E438K; 11:120125712-120125712	urinary_tract; bladder	carcinoma	Substitution - Missense
c.230G>A; p.R77Q; 11:120137802-120137802	skin	malignant_melanoma	Substitution - Missense
c.230G>A; p.R77Q; 11:120137802-120137802	skin; upper_leg	malignant_melanoma	Substitution - Missense
c.1090C>T; p.R364W; 11:120127380-120127380	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1162T>C; p.S388P; 11:120125862-120125862	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.365C>A; p.A122D; 11:120137667-120137667	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1562C>T; p.S521F; 11:120118288-120118288	breast	carcinoma	Substitution - Missense
c.387G>A; p.K129K; 11:120137645-120137645	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.487C>T; p.R163W; 11:120137545-120137545	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.792G>T; p.K264N; 11:120137240-120137240	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; hairy_cell_leukaemia	Substitution - Missense
c.1259G>T; p.C420F; 11:120125765-120125765	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.212C>T; p.A71V; 11:120137820-120137820	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.1208A>T; p.E403V; 11:120125816-120125816	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1134+5C>A; p.?; 11:120127331-120127331	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Unknown
c.14A>C; p.D5A; 11:120138018-120138018	prostate	adenoma	Substitution - Missense
c.262G>C; p.D88H; 11:120137770-120137770	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.224G>T; p.W75L; 11:120137808-120137808	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.631C>T; p.H211Y; 11:120137401-120137401	skin	malignant_melanoma	Substitution - Missense
c.226C>T; p.R76W; 11:120137806-120137806	lung	carcinoma; small_cell_carcinoma	Substitution - Missense
c.439G>A; p.E147K; 11:120137593-120137593	skin	malignant_melanoma	Substitution - Missense
c.1301G>A; p.R434H; 11:120125723-120125723	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.1461C>T; p.P487P; 11:120120640-120120640	pancreas	carcinoma; adenocarcinoma	Substitution - coding silent
c.1461C>T; p.P487P; 11:120120640-120120640	pancreas	carcinoma	Substitution - coding silent
c.817T>C; p.L273L; 11:120128483-120128483	thyroid	other; neoplasm	Substitution - coding silent
c.1290G>T; p.A430A; 11:120125734-120125734	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1655G>A; p.S552N; 11:120115387-120115387	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.124A>G; p.T42A; 11:120137908-120137908	breast	carcinoma	Substitution - Missense
c.918G>A; p.E306E; 11:120127552-120127552	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.1685C>T; p.S562F; 11:120115357-120115357	skin	malignant_melanoma	Substitution - Missense
c.375C>T; p.G125G; 11:120137657-120137657	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1118C>T; p.S373F; 11:120127352-120127352	breast	carcinoma	Substitution - Missense
c.372G>A; p.K124K; 11:120137660-120137660	skin	malignant_melanoma	Substitution - coding silent
c.449G>A; p.R150Q; 11:120137583-120137583	skin	malignant_melanoma	Substitution - Missense
c.449G>A; p.R150Q; 11:120137583-120137583	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.202G>A; p.A68T; 11:120137830-120137830	prostate	carcinoma; adenocarcinoma	Substitution - Missense
c.202G>A; p.A68T; 11:120137830-120137830	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1617C>T; p.F539F; 11:120118233-120118233	kidney	carcinoma; papillary_renal_cell_carcinoma	Substitution - coding silent
c.1279A>C; p.M427L; 11:120125745-120125745	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1184C>T; p.T395I; 11:120125840-120125840	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.222G>A; p.E74E; 11:120137810-120137810	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.1169C>T; p.P390L; 11:120125855-120125855	skin	malignant_melanoma	Substitution - Missense
c.1053T>G; p.D351E; 11:120127417-120127417	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1247T>G; p.L416R; 11:120125777-120125777	skin	malignant_melanoma	Substitution - Missense
c.1546G>T; p.V516F; 11:120118304-120118304	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.379C>G; p.L127V; 11:120137653-120137653	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.358A>C; p.T120P; 11:120137674-120137674	pancreas	carcinoma	Substitution - Missense
c.1248G>C; p.L416L; 11:120125776-120125776	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - coding silent
c.819G>A; p.L273L; 11:120128481-120128481	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.774G>T; p.V258V; 11:120137258-120137258	pancreas	carcinoma	Substitution - coding silent
c.1265G>A; p.R422H; 11:120125759-120125759	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.1265G>A; p.R422H; 11:120125759-120125759	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.210C>T; p.F70F; 11:120137822-120137822	skin	malignant_melanoma	Substitution - coding silent
c.305A>T; p.K102M; 11:120137727-120137727	lung; right_lower_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.1172delC; p.P391fs*19; 11:120125852-120125852	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.1172delC; p.P391fs*19; 11:120125852-120125852	large_intestine	carcinoma; adenocarcinoma	Deletion - Frameshift
c.52G>A; p.D18N; 11:120137980-120137980	skin; extremity	malignant_melanoma	Substitution - Missense
c.1172delC; p.P391fs*19; 11:120125852-120125852	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.1172delC; p.P391fs*19; 11:120125852-120125852	large_intestine	carcinoma; adenocarcinoma	Deletion - Frameshift
c.1495C>A; p.Q499K; 11:120120606-120120606	skin; head_neck	malignant_melanoma; superficial_spreading	Substitution - Missense
c.1035G>T; p.V345V; 11:120127435-120127435	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.367G>A; p.E123K; 11:120137665-120137665	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.77G>A; p.S26N; 11:120137955-120137955	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1082A>G; p.K361R; 11:120127388-120127388	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.958G>A; p.D320N; 11:120127512-120127512	skin	malignant_melanoma	Substitution - Missense
c.1346G>A; p.R449H; 11:120123043-120123043	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1270G>A; p.V424I; 11:120125754-120125754	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	Substitution - Missense
c.1270G>A; p.V424I; 11:120125754-120125754	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.399G>A; p.S133S; 11:120137633-120137633	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.399G>A; p.S133S; 11:120137633-120137633	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.1079A>G; p.D360G; 11:120127391-120127391	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.857A>C; p.E286A; 11:120128443-120128443	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.31G>A; p.G11R; 11:120138001-120138001	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.1291G>T; p.D431Y; 11:120125733-120125733	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.95G>A; p.G32D; 11:120137937-120137937	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1064A>C; p.K355T; 11:120127406-120127406	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.1260C>T; p.C420C; 11:120125764-120125764	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.186A>T; p.P62P; 11:120137846-120137846	lung; right_lower_lobe	carcinoma; adenocarcinoma	Substitution - coding silent
c.230G>T; p.R77L; 11:120137802-120137802	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1543C>T; p.R515W; 11:120118307-120118307	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.751G>A; p.E251K; 11:120137281-120137281	skin	malignant_melanoma	Substitution - Missense
c.1334G>T; p.G445V; 11:120123055-120123055	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.71G>A; p.G24D; 11:120137961-120137961	stomach	carcinoma; adenocarcinoma	Substitution - Missense

Annotation category 5

Basic annotation

Literature evidence

Expression

Somatic mutation

Network

ceRNA

Gene information

COSMIC somatic mutation