lung cancer gene and literature database Home

Annotation category 5

Basic annotation
Ontology and pathways
Literature evidence
Curated literatures
Expression
Gene expression chart
Somatic mutation
COSMIC and TCGA mutations
Network
Gene interaction
ceRNA
Gene-related ceRNA

Gene information

Gene ID	23603
Symbol	CORO1C
Synonymous	HCRNN4
Full name	coronin, actin binding protein, 1C
Gene description	coronin 1C\|coronin, actin-binding protein, 1C\|coronin-1C\|coronin-3
Cytoband	12q24.1
Gene type	protein-coding
Synonymous	MIM:605269; HGNC:HGNC:2254; Ensembl:ENSG00000110880; HPRD:09244; Vega:OTTHUMG00000169381

COSMIC somatic mutation

Mutation (CDS; AA; Chr)	Site	Histology	Mutation Type
c.123C>T; p.V41V; 12:108701196-108701196	urinary_tract; bladder	carcinoma	Substitution - coding silent
c.123C>T; p.V41V; 12:108701196-108701196	urinary_tract; bladder	carcinoma; transitional_cell_carcinoma	Substitution - coding silent
c.1112C>T; p.A371V; 12:108648798-108648798	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.926G>A; p.S309N; 12:108652347-108652347	skin; extremity	malignant_melanoma	Substitution - Missense
c.1166C>T; p.S389F; 12:108648744-108648744	skin	malignant_melanoma	Substitution - Missense
c.321A>G; p.V107V; 12:108662156-108662156	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.903C>T; p.Y301Y; 12:108652370-108652370	pancreas	carcinoma	Substitution - coding silent
c.903C>T; p.Y301Y; 12:108652370-108652370	pancreas	carcinoid-endocrine_tumour	Substitution - coding silent
c.727C>T; p.R243W; 12:108657327-108657327	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1382G>A; p.R461H; 12:108647446-108647446	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.34C>T; p.H12Y; 12:108701285-108701285	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.212A>C; p.K71T; 12:108678378-108678378	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.399C>T; p.V133V; 12:108662078-108662078	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.399C>T; p.V133V; 12:108662078-108662078	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.1123G>A; p.E375K; 12:108648787-108648787	lung	carcinoma; small_cell_carcinoma	Substitution - Missense
c.551G>A; p.R184Q; 12:108658817-108658817	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1190G>A; p.G397D; 12:108648720-108648720	breast	carcinoma	Substitution - Missense
c.998C>T; p.A333V; 12:108652275-108652275	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.274A>G; p.N92D; 12:108678316-108678316	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1390A>G; p.K464E; 12:108647438-108647438	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1261G>A; p.D421N; 12:108648649-108648649	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1295C>G; p.T432R; 12:108648615-108648615	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; chronic_lymphocytic_leukaemia-small_lymphocytic_lymphoma	Substitution - Missense
c.1295C>G; p.T432R; 12:108648615-108648615	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; chronic_lymphocytic_leukaemia-small_lymphocytic_lymphoma	Substitution - Missense
c.1295C>G; p.T432R; 12:108648615-108648615	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; chronic_lymphocytic_leukaemia-small_lymphocytic_lymphoma	Substitution - Missense
c.149T>C; p.I50T; 12:108701170-108701170	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.8G>C; p.R3P; 12:108701311-108701311	urinary_tract; bladder	carcinoma	Substitution - Missense
c.371T>C; p.V124A; 12:108662106-108662106	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1260C>T; p.C420C; 12:108648650-108648650	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - coding silent
c.369G>A; p.V123V; 12:108662108-108662108	oesophagus; lower_third	carcinoma; adenocarcinoma	Substitution - coding silent
c.69C>T; p.C23C; 12:108701250-108701250	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.888G>A; p.T296T; 12:108652385-108652385	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.1158C>A; p.I386I; 12:108648752-108648752	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - coding silent
c.31C>T; p.R11W; 12:108701288-108701288	urinary_tract; bladder	carcinoma	Substitution - Missense
c.472T>G; p.W158G; 12:108658896-108658896	urinary_tract; bladder	carcinoma	Substitution - Missense
c.1331T>G; p.I444S; 12:108647497-108647497	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.345C>T; p.L115L; 12:108662132-108662132	breast	carcinoma	Substitution - coding silent
c.861C>T; p.D287D; 12:108652412-108652412	skin	malignant_melanoma	Substitution - coding silent
c.1263C>T; p.D421D; 12:108648647-108648647	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.37G>T; p.V13L; 12:108701282-108701282	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.473G>T; p.W158L; 12:108658895-108658895	lung	carcinoma; small_cell_carcinoma	Substitution - Missense
c.473G>T; p.W158L; 12:108658895-108658895	lung	carcinoma; small_cell_carcinoma	Substitution - Missense
c.195G>A; p.K65K; 12:108701124-108701124	skin; arm	malignant_melanoma	Substitution - coding silent
c.1148C>T; p.A383V; 12:108648762-108648762	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1164C>G; p.I388M; 12:108648746-108648746	breast	carcinoma	Substitution - Missense
c.57A>C; p.K19N; 12:108701262-108701262	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.11T>C; p.V4A; 12:108701308-108701308	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.11T>C; p.V4A; 12:108701308-108701308	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.803T>G; p.V268G; 12:108654358-108654358	breast	carcinoma	Substitution - Missense
c.215C>G; p.S72C; 12:108678375-108678375	breast	carcinoma	Substitution - Missense
c.1264C>A; p.L422M; 12:108648646-108648646	soft_tissue; striated_muscle	rhabdomyosarcoma; embryonal	Substitution - Missense
c.1264C>A; p.L422M; 12:108648646-108648646	soft_tissue; striated_muscle	rhabdomyosarcoma; embryonal	Substitution - Missense
c.1264C>A; p.L422M; 12:108648646-108648646	soft_tissue; striated_muscle	rhabdomyosarcoma	Substitution - Missense
c.1071C>T; p.F357F; 12:108648839-108648839	skin	malignant_melanoma	Substitution - coding silent
c.203G>A; p.R68Q; 12:108678387-108678387	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.203G>A; p.R68Q; 12:108678387-108678387	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.448G>A; p.G150S; 12:108662029-108662029	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1018G>T; p.E340*; 12:108649004-108649004	lung	carcinoma; squamous_cell_carcinoma	Substitution - Nonsense
c.1420G>T; p.A474S; 12:108647408-108647408	liver	carcinoma; hepatocellular_carcinoma	Substitution - Missense
c.991G>C; p.E331Q; 12:108652282-108652282	central_nervous_system; brainstem	glioma; oligoastrocytoma_Grade_III	Substitution - Missense
c.739C>T; p.L247F; 12:108657315-108657315	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.678C>T; p.F226F; 12:108657376-108657376	skin	malignant_melanoma	Substitution - coding silent
c.1110C>T; p.A370A; 12:108648800-108648800	upper_aerodigestive_tract; mouth	carcinoma	Substitution - coding silent
c.1110C>T; p.A370A; 12:108648800-108648800	upper_aerodigestive_tract; mouth	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1134C>T; p.F378F; 12:108648776-108648776	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.1153C>T; p.P385S; 12:108648757-108648757	skin	malignant_melanoma	Substitution - Missense
c.1153C>T; p.P385S; 12:108648757-108648757	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.1372C>G; p.Q458E; 12:108647456-108647456	breast	carcinoma	Substitution - Missense
c.1154C>T; p.P385L; 12:108648756-108648756	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.926G>T; p.S309I; 12:108652347-108652347	lung; right_lower_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.1154C>T; p.P385L; 12:108648756-108648756	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.942G>C; p.Q314H; 12:108652331-108652331	lung; right_lower_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.954T>C; p.G318G; 12:108652319-108652319	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.897C>T; p.S299S; 12:108652376-108652376	skin	malignant_melanoma	Substitution - coding silent
c.1383T>C; p.R461R; 12:108647445-108647445	skin	malignant_melanoma	Substitution - coding silent
c.644C>T; p.A215V; 12:108657410-108657410	breast	carcinoma	Substitution - Missense
c.524A>T; p.D175V; 12:108658844-108658844	skin	malignant_melanoma	Substitution - Missense
c.150A>G; p.I50M; 12:108701169-108701169	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.1325A>G; p.D442G; 12:108647503-108647503	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1324G>A; p.D442N; 12:108647504-108647504	skin	malignant_melanoma	Substitution - Missense
c.353C>T; p.S118F; 12:108662124-108662124	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.353C>T; p.S118F; 12:108662124-108662124	skin	malignant_melanoma	Substitution - Missense
c.1138G>T; p.G380C; 12:108648772-108648772	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.286A>G; p.I96V; 12:108678304-108678304	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.685G>A; p.D229N; 12:108657369-108657369	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.454G>T; p.D152Y; 12:108658914-108658914	pancreas	carcinoma; ductal_carcinoma	Substitution - Missense
c.1213G>T; p.V405F; 12:108648697-108648697	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.859G>C; p.D287H; 12:108652414-108652414	central_nervous_system; brainstem	glioma; oligoastrocytoma_Grade_III	Substitution - Missense
c.329T>A; p.I110N; 12:108662148-108662148	skin	malignant_melanoma	Substitution - Missense
c.904G>A; p.V302I; 12:108652369-108652369	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.1001+1G>A; p.?; 12:108652271-108652271	endometrium	carcinoma; endometrioid_carcinoma	Unknown
c.889G>A; p.D297N; 12:108652384-108652384	skin	malignant_melanoma	Substitution - Missense
c.558C>G; p.G186G; 12:108658810-108658810	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - coding silent

Annotation category 5

Basic annotation

Literature evidence

Expression

Somatic mutation

Network

ceRNA

Gene information

COSMIC somatic mutation