Cancer metastasis database

Annotation category 5

Gene information

Gene ID 2348
Symbol

FOLR1

Synonymous

FBP|FOLR

Full name

folate receptor 1 (adult)

Gene description

FR-alpha|KB cells FBP|adult folate-binding protein|folate binding protein|folate receptor alpha|folate receptor, adult|ovarian tumor-associated antigen MOv18

Cytoband

11q13.3-q14.1

Gene type

protein-coding

Synonymous

MIM:136430; HGNC:HGNC:3791; Ensembl:ENSG00000110195; HPRD:00638; Vega:OTTHUMG00000167876

COSMIC somatic mutation

Mutation (CDS; AA; Chr)

Site

Histology

Mutation Type

c.190G>A; p.A64T; 11:72195292-72195292

 ovarycarcinoma; serous_carcinomaSubstitution - Missense

c.653A>G; p.Q218R; 11:72196056-72196056

 stomachcarcinoma; intestinal_adenocarcinomaSubstitution - Missense

c.653A>G; p.Q218R; 11:72196056-72196056

 stomachadenocarcinomaSubstitution - Missense

c.83G>A; p.W28*; 11:72192256-72192256

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Nonsense

c.705G>A; p.G235G; 11:72196108-72196108

 skinmalignant_melanomaSubstitution - coding silent

c.619G>A; p.G207S; 11:72196022-72196022

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.288C>A; p.C96*; 11:72195390-72195390

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - Nonsense

c.108C>G; p.V36V; 11:72192281-72192281

 cervixcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.388C>A; p.L130M; 11:72195642-72195642

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.426G>A; p.W142*; 11:72195680-72195680

 large_intestinecarcinoma; adenocarcinomaSubstitution - Nonsense

c.571G>A; p.E191K; 11:72195974-72195974

 ovarycarcinoma; serous_carcinomaSubstitution - Missense

c.677C>T; p.A226V; 11:72196080-72196080

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.236C>T; p.S79F; 11:72195338-72195338

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.617G>A; p.S206N; 11:72196020-72196020

 pancreascarcinomaSubstitution - Missense

c.59G>T; p.G20V; 11:72192232-72192232

 prostatecarcinoma; adenocarcinomaSubstitution - Missense

c.373C>T; p.R125C; 11:72195627-72195627

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.357G>T; p.Q119H; 11:72195459-72195459

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.132G>A; p.K44K; 11:72192305-72192305

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.67C>T; p.Q23*; 11:72192240-72192240

 cervixcarcinoma; squamous_cell_carcinomaSubstitution - Nonsense

c.11G>A; p.R4Q; 11:72192184-72192184

 skinmalignant_melanomaSubstitution - Missense

c.393C>T; p.N131N; 11:72195647-72195647

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - coding silent

c.393C>T; p.N131N; 11:72195647-72195647

 breastcarcinomaSubstitution - coding silent

c.293G>A; p.R98Q; 11:72195395-72195395

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.668A>T; p.E223V; 11:72196071-72196071

 breastcarcinomaSubstitution - Missense

c.717G>A; p.W239*; 11:72196120-72196120

 skinmalignant_melanomaSubstitution - Nonsense

c.647C>T; p.P216L; 11:72196050-72196050

 thyroidother; neoplasmSubstitution - Missense

c.728C>T; p.P243L; 11:72196131-72196131

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.229G>A; p.D77N; 11:72195331-72195331

 skinmalignant_melanomaSubstitution - Missense

c.59G>A; p.G20E; 11:72192232-72192232

 skinmalignant_melanomaSubstitution - Missense

c.232G>A; p.V78I; 11:72195334-72195334

 lung; right_upper_lobecarcinoma; adenocarcinomaSubstitution - Missense

c.507C>T; p.C169C; 11:72195910-72195910

 stomachcarcinoma; adenocarcinomaSubstitution - coding silent

c.507C>T; p.C169C; 11:72195910-72195910

 oesophaguscarcinoma; adenocarcinomaSubstitution - coding silent

c.507C>T; p.C169C; 11:72195910-72195910

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.507C>T; p.C169C; 11:72195910-72195910

 large_intestinecarcinoma; adenocarcinomaSubstitution - coding silent

c.547C>T; p.P183S; 11:72195950-72195950

 skinmalignant_melanomaSubstitution - Missense

c.133G>A; p.E45K; 11:72192306-72192306

 skinmalignant_melanomaSubstitution - Missense

c.43T>C; p.W15R; 11:72192216-72192216

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.163G>A; p.E55K; 11:72192336-72192336

 skinmalignant_melanomaSubstitution - Missense

c.74G>A; p.R25K; 11:72192247-72192247

 skinmalignant_melanomaSubstitution - Missense

c.331C>T; p.P111S; 11:72195433-72195433

 upper_aerodigestive_tract; mouthcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.268G>A; p.G90R; 11:72195370-72195370

 skinmalignant_melanomaSubstitution - Missense

c.548C>A; p.P183H; 11:72195951-72195951

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Missense

c.482A>C; p.N161T; 11:72195736-72195736

 skinmalignant_melanomaSubstitution - Missense

c.374G>A; p.R125H; 11:72195628-72195628

 central_nervous_system; brainglioma; astrocytoma_Grade_IVSubstitution - Missense

c.610C>T; p.R204*; 11:72196013-72196013

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Nonsense

c.440G>C; p.R147P; 11:72195694-72195694

 haematopoietic_and_lymphoid_tissue; central_nervous_systemlymphoid_neoplasm; primary_central_nervous_system_lymphomaSubstitution - Missense

c.623G>A; p.R208H; 11:72196026-72196026

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.678G>A; p.A226A; 11:72196081-72196081

 skinmalignant_melanomaSubstitution - coding silent

c.146_147CC>TT; p.P49L; 11:72192319-72192320

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.669G>A; p.E223E; 11:72196072-72196072

 skinmalignant_melanomaSubstitution - coding silent

c.645C>T; p.D215D; 11:72196048-72196048

 skinmalignant_melanomaSubstitution - coding silent

c.143G>A; p.G48D; 11:72192316-72192316

 pancreascarcinoma; acinar_carcinomaSubstitution - Missense

c.449A>T; p.Y150F; 11:72195703-72195703

 pancreascarcinoma; acinar_carcinomaSubstitution - Missense

c.494-2A>C; p.?; 11:72195895-72195895

 lungcarcinoma; adenocarcinomaUnknown

c.667G>A; p.E223K; 11:72196070-72196070

 skinmalignant_melanomaSubstitution - Missense

c.588C>T; p.S196S; 11:72195991-72195991

 skinmalignant_melanomaSubstitution - coding silent

c.300C>T; p.F100F; 11:72195402-72195402

 skinmalignant_melanomaSubstitution - coding silent

c.300C>T; p.F100F; 11:72195402-72195402

 skinmalignant_melanomaSubstitution - coding silent

c.648A>G; p.P216P; 11:72196051-72196051

 thyroidother; neoplasmSubstitution - coding silent