Cancer metastasis database

Annotation category 5

Gene information

Gene ID 23406
Symbol

COTL1

Synonymous

CLP

Full name

coactosin-like F-actin binding protein 1

Gene description

coactosin-like 1|coactosin-like protein

Cytoband

16q24.1

Gene type

protein-coding

Synonymous

MIM:606748; HGNC:HGNC:18304; Ensembl:ENSG00000103187; HPRD:09482; Vega:OTTHUMG00000137634

COSMIC somatic mutation

Mutation (CDS; AA; Chr)

Site

Histology

Mutation Type

c.188G>C; p.R63P; 16:84590235-84590235

 lung; right_upper_lobecarcinoma; adenocarcinomaSubstitution - Missense

c.324C>T; p.F108F; 16:84566950-84566950

 prostatecarcinoma; adenocarcinomaSubstitution - coding silent

c.324C>T; p.F108F; 16:84566950-84566950

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - coding silent

c.324C>T; p.F108F; 16:84566950-84566950

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - coding silent

c.363G>A; p.E121E; 16:84566911-84566911

 livercarcinomaSubstitution - coding silent

c.363G>A; p.E121E; 16:84566911-84566911

 livercarcinomaSubstitution - coding silent

c.363G>A; p.E121E; 16:84566911-84566911

 skinmalignant_melanomaSubstitution - coding silent

c.230C>T; p.A77V; 16:84590193-84590193

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.144C>G; p.F48L; 16:84617517-84617517

 breastcarcinomaSubstitution - Missense

c.246C>T; p.I82I; 16:84590177-84590177

 skinmalignant_melanomaSubstitution - coding silent

c.359T>A; p.L120Q; 16:84566915-84566915

 livercarcinoma; hepatocellular_carcinomaSubstitution - Missense

c.274G>A; p.A92T; 16:84590149-84590149

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.274G>A; p.A92T; 16:84590149-84590149

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.234C>T; p.L78L; 16:84590189-84590189

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.198C>T; p.T66T; 16:84590225-84590225

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.289G>T; p.D97Y; 16:84590134-84590134

 breastcarcinomaSubstitution - Missense

c.308A>G; p.E103G; 16:84590115-84590115

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.390G>A; p.K130K; 16:84566884-84566884

 lungcarcinoma; adenocarcinomaSubstitution - coding silent

c.422C>T; p.T141M; 16:84566852-84566852

 pancreascarcinomaSubstitution - Missense

c.422C>T; p.T141M; 16:84566852-84566852

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.411C>T; p.Y137Y; 16:84566863-84566863

 large_intestinecarcinoma; adenocarcinomaSubstitution - coding silent

c.411C>T; p.Y137Y; 16:84566863-84566863

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.343A>C; p.S115R; 16:84566931-84566931

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.148C>T; p.Q50*; 16:84617513-84617513

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Nonsense

c.380G>T; p.S127I; 16:84566894-84566894

 livercarcinoma; hepatocellular_carcinomaSubstitution - Missense

c.147C>T; p.I49I; 16:84617514-84617514

 skinmalignant_melanomaSubstitution - coding silent

c.413A>G; p.D138G; 16:84566861-84566861

 haematopoietic_and_lymphoid_tissuelymphoid_neoplasm; chronic_lymphocytic_leukaemia-small_lymphocytic_lymphomaSubstitution - Missense

c.174G>C; p.L58F; 16:84590249-84590249

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.401delG; p.G134fs*>9; 16:84566873-84566873

 large_intestine; coloncarcinoma; adenocarcinomaDeletion - Frameshift

c.429A>C; p.*143Y; 16:84566845-84566845

 skinmalignant_melanomaNonstop extension

c.429A>C; p.*143Y; 16:84566845-84566845

 skinmalignant_melanomaNonstop extension

c.375C>G; p.I125M; 16:84566899-84566899

 livercarcinomaSubstitution - Missense

c.256G>A; p.V86I; 16:84590167-84590167

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense