lung cancer gene and literature database Home

Annotation category 5

Basic annotation
Ontology and pathways
Literature evidence
Curated literatures
Expression
Gene expression chart
Somatic mutation
COSMIC and TCGA mutations
Network
Gene interaction
ceRNA
Gene-related ceRNA

Gene information

Gene ID	23059
Symbol	CLUAP1
Synonymous	CFAP22\|FAP22
Full name	clusterin associated protein 1
Gene description	cilia and flagella associated protein 22\|clusterin-associated protein 1\|flagellar associated protein 22, qilin-like protein, homolog\|qilin
Cytoband	16p13.3
Gene type	protein-coding
Synonymous	HGNC:HGNC:19009; Ensembl:ENSG00000103351; HPRD:10013; Vega:OTTHUMG00000177581

COSMIC somatic mutation

Mutation (CDS; AA; Chr)	Site	Histology	Mutation Type
c.1078G>C; p.D360H; 16:3532827-3532827	breast	carcinoma; ductal_carcinoma	Substitution - Missense
c.974A>T; p.D325V; 16:3530613-3530613	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.652G>A; p.E218K; 16:3519975-3519975	urinary_tract; bladder	carcinoma	Substitution - Missense
c.652G>A; p.E218K; 16:3519975-3519975	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.652G>A; p.E218K; 16:3519975-3519975	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.664T>G; p.L222V; 16:3519987-3519987	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.320C>T; p.A107V; 16:3508389-3508389	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.901G>A; p.E301K; 16:3526457-3526457	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.308T>C; p.V103A; 16:3508377-3508377	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.609C>A; p.L203L; 16:3519932-3519932	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - coding silent
c.185G>T; p.R62L; 16:3506381-3506381	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.315T>A; p.Y105*; 16:3508384-3508384	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Nonsense
c.840G>A; p.E280E; 16:3523284-3523284	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.49G>T; p.G17*; 16:3504746-3504746	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Nonsense
c.1224G>C; p.E408D; 16:3536253-3536253	pancreas	carcinoma	Substitution - Missense
c.310C>T; p.L104F; 16:3508379-3508379	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.995G>A; p.R332Q; 16:3530634-3530634	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.371A>G; p.N124S; 16:3508440-3508440	breast	carcinoma	Substitution - Missense
c.1050A>T; p.K350N; 16:3532799-3532799	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1201C>T; p.R401W; 16:3536230-3536230	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.545delA; p.V184fs*1; 16:3515557-3515557	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.454G>A; p.A152T; 16:3512437-3512437	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.147G>T; p.Q49H; 16:3506343-3506343	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.24T>C; p.N8N; 16:3504721-3504721	kidney	carcinoma; papillary_renal_cell_carcinoma	Substitution - coding silent
c.442A>G; p.T148A; 16:3512425-3512425	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.771C>T; p.D257D; 16:3523215-3523215	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.976A>G; p.S326G; 16:3530615-3530615	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.771C>T; p.D257D; 16:3523215-3523215	ovary	carcinoma; serous_carcinoma	Substitution - coding silent
c.683G>T; p.R228L; 16:3520006-3520006	prostate	carcinoma; adenocarcinoma	Substitution - Missense
c.1147G>A; p.D383N; 16:3536176-3536176	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.1002C>A; p.P334P; 16:3530641-3530641	stomach	carcinoma; diffuse_adenocarcinoma	Substitution - coding silent
c.406G>A; p.D136N; 16:3512389-3512389	lung; right_lower_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.432G>A; p.A144A; 16:3512415-3512415	upper_aerodigestive_tract; mouth	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.432G>A; p.A144A; 16:3512415-3512415	upper_aerodigestive_tract; mouth	carcinoma	Substitution - coding silent
c.689G>A; p.R230Q; 16:3520012-3520012	bone	Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	Substitution - Missense
c.1099T>C; p.S367P; 16:3536128-3536128	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1111G>C; p.E371Q; 16:3536140-3536140	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.873C>T; p.L291L; 16:3526429-3526429	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.714-1G>A; p.?; 16:3523157-3523157	ovary	other; neoplasm	Unknown
c.714-1G>A; p.?; 16:3523157-3523157	ovary	other; neoplasm	Unknown
c.714-1G>A; p.?; 16:3523157-3523157	ovary	other; neoplasm	Unknown
c.1173C>G; p.L391L; 16:3536202-3536202	liver	carcinoma	Substitution - coding silent
c.1146C>T; p.D382D; 16:3536175-3536175	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.278C>T; p.A93V; 16:3508347-3508347	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.278C>T; p.A93V; 16:3508347-3508347	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.388C>G; p.L130V; 16:3508457-3508457	breast	carcinoma	Substitution - Missense
c.400-1G>A; p.?; 16:3512382-3512382	skin	malignant_melanoma	Unknown
c.1192C>T; p.R398*; 16:3536221-3536221	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Nonsense
c.871C>A; p.L291I; 16:3526427-3526427	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.92A>C; p.N31T; 16:3504789-3504789	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.307G>T; p.V103F; 16:3508376-3508376	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.134+4C>T; p.?; 16:3504835-3504835	large_intestine; colon	carcinoma; adenocarcinoma	Unknown
c.770A>G; p.D257G; 16:3523214-3523214	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.70A>G; p.M24V; 16:3504767-3504767	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.70A>G; p.M24V; 16:3504767-3504767	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.142C>G; p.P48A; 16:3506338-3506338	urinary_tract; bladder	carcinoma	Substitution - Missense
c.98G>A; p.G33E; 16:3504795-3504795	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.630A>C; p.E210D; 16:3519953-3519953	pancreas	NS	Substitution - Missense
c.1208C>T; p.S403F; 16:3536237-3536237	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.389T>G; p.L130R; 16:3508458-3508458	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.200A>G; p.K67R; 16:3506396-3506396	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.651C>T; p.I217I; 16:3519974-3519974	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - coding silent
c.312T>C; p.L104L; 16:3508381-3508381	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - coding silent
c.1117G>T; p.D373Y; 16:3536146-3536146	breast	carcinoma	Substitution - Missense
c.185G>A; p.R62Q; 16:3506381-3506381	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.861T>C; p.A287A; 16:3526417-3526417	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1137C>T; p.D379D; 16:3536166-3536166	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.1137C>T; p.D379D; 16:3536166-3536166	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1137C>T; p.D379D; 16:3536166-3536166	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1073G>A; p.G358D; 16:3532822-3532822	lung	carcinoma; adenocarcinoma	Substitution - Missense

Annotation category 5

Basic annotation

Literature evidence

Expression

Somatic mutation

Network

ceRNA

Gene information

COSMIC somatic mutation