Cancer metastasis database

Annotation category 5

Gene information

Gene ID 2295
Symbol

FOXF2

Synonymous

FKHL6|FREAC-2|FREAC2

Full name

forkhead box F2

Gene description

forkhead box protein F2|forkhead-like 6|forkhead-related activator 2|forkhead-related protein FKHL6|forkhead-related transcription factor 2

Cytoband

6p25.3

Gene type

protein-coding

Synonymous

MIM:603250; HGNC:HGNC:3810; Ensembl:ENSG00000137273; HPRD:09131; Vega:OTTHUMG00000016243

COSMIC somatic mutation

Mutation (CDS; AA; Chr)

Site

Histology

Mutation Type

c.1130A>G; p.E377G; 6:1391077-1391077

 central_nervous_system; brainglioma; astrocytoma_Grade_IVSubstitution - Missense

c.590G>A; p.R197K; 6:1390537-1390537

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Missense

c.387C>A; p.F129L; 6:1390334-1390334

 urinary_tract; bladdercarcinomaSubstitution - Missense

c.471C>T; p.C157C; 6:1390418-1390418

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.646T>C; p.F216L; 6:1390593-1390593

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.365C>T; p.T122M; 6:1390312-1390312

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.499C>T; p.R167W; 6:1390446-1390446

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - Missense

c.311C>T; p.S104L; 6:1390258-1390258

 urinary_tract; bladdercarcinomaSubstitution - Missense

c.304C>T; p.P102S; 6:1390251-1390251

 skinmalignant_melanomaSubstitution - Missense

c.293C>A; p.P98H; 6:1390240-1390240

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Missense

c.327C>T; p.I109I; 6:1390274-1390274

 breastcarcinomaSubstitution - coding silent

c.989A>T; p.H330L; 6:1390936-1390936

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.896C>T; p.A299V; 6:1390843-1390843

 pancreascarcinomaSubstitution - Missense

c.147G>A; p.S49S; 6:1390094-1390094

 ovaryother; neoplasmSubstitution - coding silent

c.302C>T; p.P101L; 6:1390249-1390249

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.418G>A; p.A140T; 6:1390365-1390365

 oesophaguscarcinoma; adenocarcinomaSubstitution - Missense

c.633G>T; p.V211V; 6:1390580-1390580

 lungcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.465C>A; p.N155K; 6:1390412-1390412

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.920A>G; p.D307G; 6:1390867-1390867

 haematopoietic_and_lymphoid_tissue; abdomenlymphoid_neoplasm; follicular_lymphomaSubstitution - Missense

c.446G>C; p.R149P; 6:1390393-1390393

 pancreascarcinoid-endocrine_tumourSubstitution - Missense

c.899C>G; p.A300G; 6:1390846-1390846

 pancreascarcinoma; acinar_carcinomaSubstitution - Missense

c.1184G>A; p.R395H; 6:1394708-1394708

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.904_905insGGC; p.G302_G303insR; 6:1390851-1390852

 biliary_tract; bile_ductcarcinoma; adenocarcinomaInsertion - In frame

c.1228G>A; p.V410I; 6:1394752-1394752

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - Missense

c.1253C>T; p.S418F; 6:1394777-1394777

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.1291C>G; p.H431D; 6:1394815-1394815

 lung; right_upper_lobecarcinoma; adenocarcinomaSubstitution - Missense

c.600C>T; p.C200C; 6:1390547-1390547

 lungcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.388C>T; p.L130L; 6:1390335-1390335

 breastcarcinomaSubstitution - coding silent

c.146C>A; p.S49*; 6:1390093-1390093

 ovaryother; neoplasmSubstitution - Nonsense

c.344G>T; p.S115I; 6:1390291-1390291

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.493C>G; p.L165V; 6:1390440-1390440

 kidneycarcinoma; papillary_renal_cell_carcinomaSubstitution - Missense

c.378C>A; p.I126I; 6:1390325-1390325

 urinary_tract; bladdercarcinomaSubstitution - coding silent

c.1272C>T; p.S424S; 6:1394796-1394796

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.1109G>C; p.S370T; 6:1391056-1391056

 lung; right_upper_lobecarcinoma; adenocarcinomaSubstitution - Missense

c.502C>A; p.P168T; 6:1390449-1390449

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.1327G>A; p.V443I; 6:1394851-1394851

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.1250C>T; p.S417F; 6:1394774-1394774

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.1033G>A; p.A345T; 6:1390980-1390980

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.1033G>A; p.A345T; 6:1390980-1390980

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.1284T>C; p.Y428Y; 6:1394808-1394808

 haematopoietic_and_lymphoid_tissuehaematopoietic_neoplasm; acute_myeloid_leukaemiaSubstitution - coding silent

c.576G>A; p.R192R; 6:1390523-1390523

 prostatecarcinoma; adenocarcinomaSubstitution - coding silent

c.330C>T; p.V110V; 6:1390277-1390277

 lungcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.1183C>T; p.R395C; 6:1394707-1394707

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.1188C>G; p.Y396*; 6:1394712-1394712

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Nonsense

c.595A>T; p.K199*; 6:1390542-1390542

 large_intestinecarcinoma; adenocarcinomaSubstitution - Nonsense

c.319G>A; p.A107T; 6:1390266-1390266

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.1222G>T; p.D408Y; 6:1394746-1394746

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.1222G>T; p.D408Y; 6:1394746-1394746

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.1309C>T; p.Q437*; 6:1394833-1394833

 large_intestine; coloncarcinomaSubstitution - Nonsense

c.1309C>T; p.Q437*; 6:1394833-1394833

 large_intestinecarcinoma; adenocarcinomaSubstitution - Nonsense

c.1114T>C; p.S372P; 6:1391061-1391061

 lungcarcinoma; small_cell_carcinomaSubstitution - Missense

c.592C>T; p.R198W; 6:1390539-1390539

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Missense

c.548T>C; p.M183T; 6:1390495-1390495

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense