lung cancer gene and literature database Home

Annotation category 5

Basic annotation
Ontology and pathways
Literature evidence
Curated literatures
Expression
Gene expression chart
Somatic mutation
COSMIC and TCGA mutations
Network
Gene interaction
ceRNA
Gene-related ceRNA

Gene information

Gene ID	22846
Symbol	VASH1
Synonymous	KIAA1036
Full name	vasohibin 1
Gene description	vasohibin-1
Cytoband	14q24.3
Gene type	protein-coding
Synonymous	MIM:609011; HGNC:HGNC:19964; Ensembl:ENSG00000071246; HPRD:12353; Vega:OTTHUMG00000171493

COSMIC somatic mutation

Mutation (CDS; AA; Chr)	Site	Histology	Mutation Type
c.192G>A; p.R64R; 14:76763013-76763013	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.18G>A; p.K6K; 14:76762839-76762839	skin	malignant_melanoma	Substitution - coding silent
c.701G>A; p.R234H; 14:76776062-76776062	urinary_tract; bladder	carcinoma	Substitution - Missense
c.701G>A; p.R234H; 14:76776062-76776062	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.591C>A; p.F197L; 14:76775952-76775952	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.562C>T; p.R188C; 14:76775923-76775923	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.591C>A; p.F197L; 14:76775952-76775952	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.591C>A; p.F197L; 14:76775952-76775952	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.665G>A; p.R222Q; 14:76776026-76776026	skin	malignant_melanoma	Substitution - Missense
c.665G>A; p.R222Q; 14:76776026-76776026	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.384C>T; p.Y128Y; 14:76770037-76770037	liver	carcinoma; hepatocellular_carcinoma	Substitution - coding silent
c.384C>T; p.Y128Y; 14:76770037-76770037	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - coding silent
c.450G>C; p.L150L; 14:76771241-76771241	ovary	carcinoma; serous_carcinoma	Substitution - coding silent
c.222G>A; p.W74*; 14:76763043-76763043	upper_aerodigestive_tract; mouth	carcinoma; squamous_cell_carcinoma	Substitution - Nonsense
c.222G>A; p.W74*; 14:76763043-76763043	upper_aerodigestive_tract; mouth	carcinoma	Substitution - Nonsense
c.667C>T; p.R223C; 14:76776028-76776028	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.399G>T; p.Q133H; 14:76771190-76771190	breast	carcinoma	Substitution - Missense
c.1025G>T; p.R342L; 14:76778071-76778071	breast	carcinoma	Substitution - Missense
c.829C>A; p.H277N; 14:76776190-76776190	pancreas	carcinoma	Substitution - Missense
c.313C>T; p.P105S; 14:76769966-76769966	skin	malignant_melanoma	Substitution - Missense
c.313C>T; p.P105S; 14:76769966-76769966	skin	malignant_melanoma	Substitution - Missense
c.1026-3C>T; p.?; 14:76778943-76778943	stomach	carcinoma; adenocarcinoma	Unknown
c.1026-3C>T; p.?; 14:76778943-76778943	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Unknown
c.1026-3C>T; p.?; 14:76778943-76778943	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Unknown
c.972C>T; p.S324S; 14:76778018-76778018	skin	malignant_melanoma	Substitution - coding silent
c.1051G>A; p.E351K; 14:76778971-76778971	stomach	carcinoma; intestinal_adenocarcinoma	Substitution - Missense
c.615C>T; p.I205I; 14:76775976-76775976	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.860G>A; p.R287H; 14:76776221-76776221	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.1032G>T; p.S344S; 14:76778952-76778952	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.275C>T; p.A92V; 14:76763096-76763096	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.275C>T; p.A92V; 14:76763096-76763096	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.846G>A; p.V282V; 14:76776207-76776207	skin	malignant_melanoma	Substitution - coding silent
c.1058A>G; p.K353R; 14:76778978-76778978	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.792A>G; p.S264S; 14:76776153-76776153	breast	carcinoma	Substitution - coding silent
c.427G>C; p.E143Q; 14:76771218-76771218	breast	carcinoma	Substitution - Missense
c.782A>G; p.Q261R; 14:76776143-76776143	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.54G>A; p.T18T; 14:76762875-76762875	pancreas	carcinoma	Substitution - coding silent
c.24_25insG; p.G11fs*33; 14:76762845-76762846	autonomic_ganglia	neuroblastoma	Insertion - Frameshift
c.882G>A; p.L294L; 14:76776243-76776243	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.413G>A; p.G138E; 14:76771204-76771204	oesophagus	carcinoma	Substitution - Missense
c.808G>A; p.V270M; 14:76776169-76776169	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.433A>G; p.K145E; 14:76771224-76771224	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.423C>A; p.F141L; 14:76771214-76771214	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.213G>T; p.E71D; 14:76763034-76763034	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.891C>T; p.H297H; 14:76776252-76776252	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.891C>T; p.H297H; 14:76776252-76776252	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.973_974CC>TT; p.P325L; 14:76778019-76778020	skin; neck	malignant_melanoma	Substitution - Missense
c.39C>T; p.S13S; 14:76762860-76762860	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.398+1G>T; p.?; 14:76770052-76770052	prostate	carcinoma; adenocarcinoma	Unknown
c.566_567insC; p.I191fs*99; 14:76775927-76775928	large_intestine; colon	carcinoma; adenocarcinoma	Insertion - Frameshift
c.843C>T; p.D281D; 14:76776204-76776204	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.587A>G; p.Y196C; 14:76775948-76775948	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.704C>T; p.T235M; 14:76776065-76776065	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.704C>T; p.T235M; 14:76776065-76776065	breast	carcinoma	Substitution - Missense
c.180C>A; p.F60L; 14:76763001-76763001	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.587A>C; p.Y196S; 14:76775948-76775948	thyroid	other; neoplasm	Substitution - Missense
c.1053G>T; p.E351D; 14:76778973-76778973	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.7delG; p.K5fs*146; 14:76762828-76762828	oesophagus	carcinoma; adenocarcinoma	Deletion - Frameshift
c.7delG; p.K5fs*146; 14:76762828-76762828	large_intestine; caecum	carcinoma; adenocarcinoma	Deletion - Frameshift
c.7delG; p.K5fs*146; 14:76762828-76762828	stomach	carcinoma; intestinal_adenocarcinoma	Deletion - Frameshift
c.7delG; p.K5fs*146; 14:76762828-76762828	large_intestine; caecum	carcinoma; adenocarcinoma	Deletion - Frameshift
c.7delG; p.K5fs*146; 14:76762828-76762828	large_intestine	carcinoma; adenocarcinoma	Deletion - Frameshift
c.608_609GC>AT; p.R203>?; 14:76775969-76775970	urinary_tract; bladder	carcinoma	Complex
c.987G>T; p.Q329H; 14:76778033-76778033	lung	carcinoma; non_small_cell_carcinoma	Substitution - Missense
c.925A>G; p.T309A; 14:76777971-76777971	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.765G>A; p.K255K; 14:76776126-76776126	urinary_tract; bladder	carcinoma	Substitution - coding silent
c.608G>A; p.R203H; 14:76775969-76775969	urinary_tract; bladder	carcinoma	Substitution - Missense
c.1069G>T; p.D357Y; 14:76778989-76778989	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.609C>T; p.R203R; 14:76775970-76775970	urinary_tract; bladder	carcinoma	Substitution - coding silent
c.165C>T; p.D55D; 14:76762986-76762986	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.573C>A; p.I191I; 14:76775934-76775934	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.165C>T; p.D55D; 14:76762986-76762986	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.276G>A; p.A92A; 14:76763097-76763097	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.932C>A; p.P311H; 14:76777978-76777978	ovary	other; neoplasm	Substitution - Missense
c.971C>T; p.S324F; 14:76778017-76778017	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.862G>A; p.D288N; 14:76776223-76776223	skin	malignant_melanoma	Substitution - Missense
c.862G>A; p.D288N; 14:76776223-76776223	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.102C>T; p.S34S; 14:76762923-76762923	pancreas	carcinoma	Substitution - coding silent
c.172G>A; p.V58I; 14:76762993-76762993	prostate	adenoma	Substitution - Missense
c.172G>A; p.V58I; 14:76762993-76762993	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.172G>A; p.V58I; 14:76762993-76762993	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.530+6C>A; p.?; 14:76773217-76773217	endometrium	carcinoma; endometrioid_carcinoma	Unknown
c.940C>T; p.P314S; 14:76777986-76777986	skin	malignant_melanoma	Substitution - Missense
c.326T>G; p.V109G; 14:76769979-76769979	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.319C>T; p.P107S; 14:76769972-76769972	skin	malignant_melanoma	Substitution - Missense

Annotation category 5

Basic annotation

Literature evidence

Expression

Somatic mutation

Network

ceRNA

Gene information

COSMIC somatic mutation