Cancer metastasis database

Annotation category 5

Gene information

Gene ID 2277
Symbol

FIGF

Synonymous

VEGF-D|VEGFD

Full name

c-fos induced growth factor (vascular endothelial growth factor D)

Gene description

vascular endothelial growth factor D

Cytoband

Xp22.31

Gene type

protein-coding

Synonymous

MIM:300091; HGNC:HGNC:3708; Ensembl:ENSG00000165197; HPRD:02102; Vega:OTTHUMG00000021175

COSMIC somatic mutation

Mutation (CDS; AA; Chr)

Site

Histology

Mutation Type

c.1052G>A; p.R351Q; 23:15346146-15346146

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.1009C>T; p.R337C; 23:15346189-15346189

 central_nervous_system; brainglioma; astrocytoma_Grade_IVSubstitution - Missense

c.15G>T; p.W5C; 23:15383932-15383932

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - Missense

c.1009C>T; p.R337C; 23:15346189-15346189

 central_nervous_system; brainglioma; astrocytoma_Grade_IVSubstitution - Missense

c.696A>G; p.K232K; 23:15353114-15353114

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.801T>C; p.D267D; 23:15347301-15347301

 haematopoietic_and_lymphoid_tissuelymphoid_neoplasm; Burkitt_lymphomaSubstitution - coding silent

c.422G>A; p.R141Q; 23:15358073-15358073

 haematopoietic_and_lymphoid_tissuelymphoid_neoplasm; hairy_cell_leukaemiaSubstitution - Missense

c.238C>T; p.R80C; 23:15363172-15363172

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Missense

c.13T>A; p.W5R; 23:15383934-15383934

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.846C>G; p.I282M; 23:15347256-15347256

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.55G>A; p.V19M; 23:15383892-15383892

 oesophaguscarcinomaSubstitution - Missense

c.347C>T; p.T116M; 23:15358148-15358148

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - Missense

c.804T>C; p.R268R; 23:15347298-15347298

 central_nervous_system; braingliomaSubstitution - coding silent

c.281_282insGA; p.Y94fs*1; 23:15363128-15363129

 boneEwings_sarcoma-peripheral_primitive_neuroectodermal_tumourInsertion - Frameshift

c.43T>C; p.Y15H; 23:15383904-15383904

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.153G>A; p.E51E; 23:15363257-15363257

 lungcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.686A>C; p.D229A; 23:15353124-15353124

 skinmalignant_melanomaSubstitution - Missense

c.805T>A; p.C269S; 23:15347297-15347297

 skinmalignant_melanomaSubstitution - Missense

c.1031C>A; p.A344D; 23:15346167-15346167

 haematopoietic_and_lymphoid_tissuelymphoid_neoplasm; follicular_lymphomaSubstitution - Missense

c.270G>A; p.A90A; 23:15363140-15363140

 large_intestinecarcinoma; adenocarcinomaSubstitution - coding silent

c.163C>T; p.R55*; 23:15363247-15363247

 oesophaguscarcinoma; adenocarcinomaSubstitution - Nonsense

c.163C>T; p.R55*; 23:15363247-15363247

 central_nervous_system; brainglioma; astrocytoma_Grade_IVSubstitution - Nonsense

c.529G>A; p.E177K; 23:15355262-15355262

 breastcarcinoma; ductal_carcinomaSubstitution - Missense

c.694A>G; p.K232E; 23:15353116-15353116

 central_nervous_system; brainglioma; astrocytoma_Grade_IVSubstitution - Missense

c.403C>T; p.P135S; 23:15358092-15358092

 ovarycarcinoma; serous_carcinomaSubstitution - Missense

c.590G>A; p.R197H; 23:15355201-15355201

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.323G>T; p.R108I; 23:15358172-15358172

 breastcarcinomaSubstitution - Missense

c.323G>T; p.R108I; 23:15358172-15358172

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.323G>T; p.R108I; 23:15358172-15358172

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - Missense

c.311A>C; p.E104A; 23:15358184-15358184

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.874G>A; p.E292K; 23:15347228-15347228

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.1003C>T; p.H335Y; 23:15346195-15346195

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.968G>T; p.R323I; 23:15346230-15346230

 skinmalignant_melanomaSubstitution - Missense

c.129G>T; p.Q43H; 23:15363281-15363281

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.733G>A; p.G245R; 23:15353077-15353077

 oesophagus; lower_thirdcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.860delA; p.N287fs*>68; 23:15347242-15347242

 large_intestine; caecumcarcinoma; adenocarcinomaDeletion - Frameshift

c.3G>A; p.M1I; 23:15383944-15383944

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.997G>T; p.A333S; 23:15346201-15346201

 salivary_glandcarcinoma; adenoid_cystic_carcinomaSubstitution - Missense

c.275C>G; p.T92S; 23:15363135-15363135

 breastcarcinomaSubstitution - Missense

c.91-4delT; p.?; 23:15363323-15363323

 livercarcinomaUnknown

c.920T>C; p.F307S; 23:15347182-15347182

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.928G>C; p.D310H; 23:15347174-15347174

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.421C>T; p.R141*; 23:15358074-15358074

 skinmalignant_melanomaSubstitution - Nonsense

c.204G>A; p.R68R; 23:15363206-15363206

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.470G>A; p.S157N; 23:15358025-15358025

 skinmalignant_melanomaSubstitution - Missense

c.284A>T; p.D95V; 23:15363126-15363126

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.1040G>A; p.G347E; 23:15346158-15346158

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.1036C>T; p.Q346*; 23:15346162-15346162

 skin; facecarcinoma; squamous_cell_carcinomaSubstitution - Nonsense

c.45C>T; p.Y15Y; 23:15383902-15383902

 stomachcarcinoma; adenocarcinomaSubstitution - coding silent

c.961C>T; p.H321Y; 23:15346237-15346237

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.473C>T; p.T158I; 23:15358022-15358022

 skinmalignant_melanomaSubstitution - Missense

c.856A>C; p.K286Q; 23:15347246-15347246

 thyroidcarcinomaSubstitution - Missense

c.880A>C; p.K294Q; 23:15347222-15347222

 upper_aerodigestive_tract; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.456C>T; p.I152I; 23:15358039-15358039

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.922C>T; p.H308Y; 23:15347180-15347180

 NSNSSubstitution - Missense

c.393C>A; p.F131L; 23:15358102-15358102

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - Missense

c.190C>G; p.L64V; 23:15363220-15363220

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.289G>A; p.E97K; 23:15363121-15363121

 breastcarcinomaSubstitution - Missense

c.609C>T; p.I203I; 23:15355182-15355182

 endometriumcarcinoma; serous_carcinomaSubstitution - coding silent

c.1051C>A; p.R351R; 23:15346147-15346147

 breastcarcinomaSubstitution - coding silent

c.726A>G; p.P242P; 23:15353084-15353084

 livercarcinomaSubstitution - coding silent

c.372G>T; p.L124L; 23:15358123-15358123

 lungcarcinoma; adenocarcinomaSubstitution - coding silent

c.100C>A; p.Q34K; 23:15363310-15363310

 urinary_tract; bladdercarcinomaSubstitution - Missense

c.939-1G>A; p.?; 23:15346260-15346260

 large_intestine; coloncarcinoma; adenocarcinomaUnknown

c.617C>A; p.S206Y; 23:15355174-15355174

 lungcarcinoma; small_cell_carcinomaSubstitution - Missense

c.718G>A; p.E240K; 23:15353092-15353092

 urinary_tract; bladdercarcinomaSubstitution - Missense

c.962A>G; p.H321R; 23:15346236-15346236

 breastcarcinomaSubstitution - Missense