lung cancer gene and literature database Home

Annotation category 5

Basic annotation
Ontology and pathways
Literature evidence
Curated literatures
Expression
Gene expression chart
Somatic mutation
COSMIC and TCGA mutations
Network
Gene interaction
ceRNA
Gene-related ceRNA

Gene information

Gene ID	2243
Symbol	FGA
Synonymous	Fib2
Full name	fibrinogen alpha chain
Gene description	fibrinogen, A alpha polypeptide
Cytoband	4q28
Gene type	protein-coding
Synonymous	MIM:134820; HGNC:HGNC:3661; Ensembl:ENSG00000171560; HPRD:00619; Vega:OTTHUMG00000150330

COSMIC somatic mutation

Mutation (CDS; AA; Chr)	Site	Histology	Mutation Type
c.1851T>C; p.H617H; 4:154585578-154585578	liver	carcinoma; hepatocellular_carcinoma	Substitution - coding silent
c.367C>T; p.R123C; 4:154587655-154587655	skin	malignant_melanoma	Substitution - Missense
c.1010G>T; p.G337V; 4:154586419-154586419	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1892-3delT; p.?; 4:154584836-154584836	oesophagus; lower_third	carcinoma; adenocarcinoma	Unknown
c.633C>A; p.D211E; 4:154586796-154586796	breast	carcinoma	Substitution - Missense
c.145G>T; p.D49Y; 4:154589472-154589472	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.2439A>G; p.Q813Q; 4:154584286-154584286	lung	carcinoma; small_cell_carcinoma	Substitution - coding silent
c.426G>A; p.K142K; 4:154587596-154587596	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1206C>T; p.N402N; 4:154586223-154586223	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.2539A>T; p.R847*; 4:154584186-154584186	liver	carcinoma	Substitution - Nonsense
c.2104G>A; p.E702K; 4:154584621-154584621	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.115G>T; p.V39F; 4:154589502-154589502	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2104G>A; p.E702K; 4:154584621-154584621	skin	malignant_melanoma	Substitution - Missense
c.896G>A; p.S299N; 4:154586533-154586533	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.703G>A; p.G235R; 4:154586726-154586726	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2104G>A; p.E702K; 4:154584621-154584621	skin	malignant_melanoma	Substitution - Missense
c.2539A>T; p.R847*; 4:154584186-154584186	liver	carcinoma	Substitution - Nonsense
c.2104G>A; p.E702K; 4:154584621-154584621	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2340C>T; p.H780H; 4:154584385-154584385	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.2233G>T; p.G745C; 4:154584492-154584492	urinary_tract; bladder	carcinoma	Substitution - Missense
c.2569C>T; p.R857C; 4:154584156-154584156	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.2569C>T; p.R857C; 4:154584156-154584156	skin	malignant_melanoma	Substitution - Missense
c.2569C>T; p.R857C; 4:154584156-154584156	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2569C>T; p.R857C; 4:154584156-154584156	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.2569C>T; p.R857C; 4:154584156-154584156	central_nervous_system; brain	primitive_neuroectodermal_tumour-medulloblastoma	Substitution - Missense
c.1701A>G; p.I567M; 4:154585728-154585728	pancreas	carcinoma; acinar_carcinoma	Substitution - Missense
c.2245G>C; p.E749Q; 4:154584480-154584480	cervix	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2229G>C; p.R743R; 4:154584496-154584496	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - coding silent
c.868A>C; p.S290R; 4:154586561-154586561	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.43G>T; p.G15C; 4:154590645-154590645	soft_tissue; striated_muscle	rhabdomyosarcoma	Substitution - Missense
c.43G>T; p.G15C; 4:154590645-154590645	soft_tissue; striated_muscle	rhabdomyosarcoma; embryonal	Substitution - Missense
c.2183T>C; p.L728S; 4:154584542-154584542	skin	malignant_melanoma	Substitution - Missense
c.2518G>T; p.G840*; 4:154584207-154584207	breast	carcinoma	Substitution - Nonsense
c.2518G>T; p.G840*; 4:154584207-154584207	breast	carcinoma	Substitution - Nonsense
c.1953G>T; p.K651N; 4:154584772-154584772	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1268G>A; p.G423E; 4:154586161-154586161	skin	malignant_melanoma	Substitution - Missense
c.757G>A; p.D253N; 4:154586672-154586672	skin; face	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1978_1979insT; p.S660fs*27; 4:154584746-154584747	large_intestine; colon	carcinoma; adenocarcinoma	Insertion - Frameshift
c.744G>C; p.W248C; 4:154586685-154586685	urinary_tract; bladder	carcinoma	Substitution - Missense
c.2252A>T; p.Y751F; 4:154584473-154584473	skin	malignant_melanoma	Substitution - Missense
c.2025C>T; p.I675I; 4:154584700-154584700	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.1198T>G; p.S400A; 4:154586231-154586231	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.555T>G; p.S185R; 4:154586874-154586874	stomach	adenocarcinoma	Substitution - Missense
c.2025C>T; p.I675I; 4:154584700-154584700	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1171G>A; p.G391R; 4:154586258-154586258	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.2082_2083delAG; p.G695fs*6; 4:154584642-154584643	liver	carcinoma; hepatocellular_carcinoma	Deletion - Frameshift
c.2588T>C; p.L863P; 4:154584137-154584137	thyroid	carcinoma	Substitution - Missense
c.1494C>T; p.G498G; 4:154585935-154585935	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.2555C>T; p.S852F; 4:154584170-154584170	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1889G>A; p.R630K; 4:154585540-154585540	urinary_tract; bladder	carcinoma	Substitution - Missense
c.2555C>T; p.S852F; 4:154584170-154584170	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2555C>T; p.S852F; 4:154584170-154584170	skin	malignant_melanoma	Substitution - Missense
c.1541C>A; p.P514H; 4:154585888-154585888	lung; right_lower_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.995G>A; p.G332E; 4:154586434-154586434	skin	malignant_melanoma	Substitution - Missense
c.1071C>A; p.T357T; 4:154586358-154586358	skin	malignant_melanoma	Substitution - coding silent
c.1099C>T; p.R367C; 4:154586330-154586330	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.2416G>A; p.G806S; 4:154584309-154584309	lung	carcinoma; small_cell_carcinoma	Substitution - Missense
c.2455G>A; p.G819R; 4:154584270-154584270	skin	malignant_melanoma	Substitution - Missense
c.2116G>T; p.E706*; 4:154584609-154584609	large_intestine	carcinoma; adenocarcinoma	Substitution - Nonsense
c.1866C>A; p.G622G; 4:154585563-154585563	lung	carcinoma; small_cell_carcinoma	Substitution - coding silent
c.2116G>T; p.E706*; 4:154584609-154584609	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Nonsense
c.1475C>T; p.P492L; 4:154585954-154585954	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.814G>A; p.G272R; 4:154586615-154586615	skin	malignant_melanoma	Substitution - Missense
c.431_432delAA; p.K144fs*16; 4:154587590-154587591	liver	carcinoma	Deletion - Frameshift
c.1643G>A; p.G548D; 4:154585786-154585786	skin	malignant_melanoma	Substitution - Missense
c.2489G>A; p.R830K; 4:154584236-154584236	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1257_1258insT; p.V420fs*18; 4:154586171-154586172	liver	carcinoma	Insertion - Frameshift
c.2233_2234GG>TT; p.G745>?; 4:154584491-154584492	urinary_tract; bladder	carcinoma	Complex
c.1781C>T; p.S594F; 4:154585648-154585648	skin	malignant_melanoma	Substitution - Missense
c.99C>T; p.G33G; 4:154589518-154589518	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.99C>T; p.G33G; 4:154589518-154589518	central_nervous_system; brain	primitive_neuroectodermal_tumour-medulloblastoma	Substitution - coding silent
c.1736A>G; p.Y579C; 4:154585693-154585693	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1641G>T; p.R547S; 4:154585788-154585788	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.585G>T; p.K195N; 4:154586844-154586844	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.460C>A; p.L154I; 4:154587562-154587562	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.2489G>T; p.R830M; 4:154584236-154584236	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1060C>A; p.P354T; 4:154586369-154586369	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.2540G>C; p.R847T; 4:154584185-154584185	upper_aerodigestive_tract; mouth	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2089G>A; p.G697S; 4:154584636-154584636	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.1456G>A; p.E486K; 4:154585973-154585973	skin	malignant_melanoma	Substitution - Missense
c.1456G>A; p.E486K; 4:154585973-154585973	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.346G>A; p.D116N; 4:154588811-154588811	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1102G>A; p.G368R; 4:154586327-154586327	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1103G>T; p.G368V; 4:154586326-154586326	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.395A>G; p.E132G; 4:154587627-154587627	liver	carcinoma	Substitution - Missense
c.395A>G; p.E132G; 4:154587627-154587627	liver	carcinoma	Substitution - Missense
c.1479G>T; p.E493D; 4:154585950-154585950	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1158G>A; p.W386*; 4:154586271-154586271	lung	carcinoma; adenocarcinoma	Substitution - Nonsense
c.864C>A; p.N288K; 4:154586565-154586565	oesophagus; middle_third	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2564C>A; p.A855D; 4:154584161-154584161	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.2564C>A; p.A855D; 4:154584161-154584161	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1452C>T; p.T484T; 4:154585977-154585977	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.74G>T; p.G25V; 4:154589543-154589543	breast	carcinoma	Substitution - Missense
c.1043A>T; p.N348I; 4:154586386-154586386	prostate	carcinoma	Substitution - Missense
c.588C>T; p.D196D; 4:154586841-154586841	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.1561G>A; p.D521N; 4:154585868-154585868	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.1561G>A; p.D521N; 4:154585868-154585868	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.1879C>T; p.R627C; 4:154585550-154585550	skin	malignant_melanoma	Substitution - Missense
c.1150G>A; p.G384R; 4:154586279-154586279	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1879C>T; p.R627C; 4:154585550-154585550	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.528G>C; p.K176N; 4:154586901-154586901	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.1372C>T; p.R458C; 4:154586057-154586057	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.528G>C; p.K176N; 4:154586901-154586901	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.1830A>G; p.E610E; 4:154585599-154585599	skin	malignant_melanoma	Substitution - coding silent
c.1778A>T; p.D593V; 4:154585651-154585651	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1778A>T; p.D593V; 4:154585651-154585651	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.983C>G; p.P328R; 4:154586446-154586446	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1805A>C; p.K602T; 4:154585624-154585624	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1375C>T; p.R459C; 4:154586054-154586054	skin	malignant_melanoma	Substitution - Missense
c.963G>A; p.W321*; 4:154586466-154586466	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Nonsense
c.987A>G; p.G329G; 4:154586442-154586442	oesophagus	carcinoma; adenocarcinoma	Substitution - coding silent
c.541C>T; p.R181*; 4:154586888-154586888	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Nonsense
c.2066G>A; p.W689*; 4:154584659-154584659	stomach	carcinoma; diffuse_adenocarcinoma	Substitution - Nonsense
c.968C>T; p.P323L; 4:154586461-154586461	skin	malignant_melanoma	Substitution - Missense
c.1504G>A; p.G502S; 4:154585925-154585925	skin	malignant_melanoma	Substitution - Missense
c.1663A>G; p.T555A; 4:154585766-154585766	breast	carcinoma	Substitution - Missense
c.640C>T; p.P214S; 4:154586789-154586789	skin	malignant_melanoma	Substitution - Missense
c.640C>T; p.P214S; 4:154586789-154586789	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.565G>T; p.A189S; 4:154586864-154586864	urinary_tract; bladder	carcinoma	Substitution - Missense
c.2320G>T; p.G774W; 4:154584405-154584405	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1094C>T; p.S365F; 4:154586335-154586335	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.427C>T; p.R143C; 4:154587595-154587595	pancreas	carcinoma	Substitution - Missense
c.354C>T; p.S118S; 4:154588803-154588803	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.2198G>A; p.G733E; 4:154584527-154584527	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.1846A>G; p.T616A; 4:154585583-154585583	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.427C>T; p.R143C; 4:154587595-154587595	pancreas	carcinoma	Substitution - Missense
c.2323G>T; p.A775S; 4:154584402-154584402	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; T_cell_large_granular_lymphocytic_leukaemia	Substitution - Missense
c.1761G>C; p.T587T; 4:154585668-154585668	urinary_tract; bladder	carcinoma	Substitution - coding silent
c.1526T>A; p.F509Y; 4:154585903-154585903	skin	malignant_melanoma	Substitution - Missense
c.2317G>A; p.E773K; 4:154584408-154584408	skin	malignant_melanoma	Substitution - Missense
c.1675G>A; p.E559K; 4:154585754-154585754	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1192C>T; p.P398S; 4:154586237-154586237	skin	malignant_melanoma	Substitution - Missense
c.923G>A; p.R308Q; 4:154586506-154586506	central_nervous_system; brain	glioma	Substitution - Missense
c.732A>G; p.V244V; 4:154586697-154586697	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.510G>T; p.E170D; 4:154587512-154587512	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.923G>A; p.R308Q; 4:154586506-154586506	skin	malignant_melanoma	Substitution - Missense
c.923G>A; p.R308Q; 4:154586506-154586506	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.923G>A; p.R308Q; 4:154586506-154586506	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2449C>A; p.L817I; 4:154584276-154584276	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.755C>G; p.T252R; 4:154586674-154586674	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.1575T>A; p.T525T; 4:154585854-154585854	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1391_1392CC>AA; p.T464K; 4:154586037-154586038	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.209T>C; p.M70T; 4:154588948-154588948	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2365G>A; p.D789N; 4:154584360-154584360	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.312G>A; p.S104S; 4:154588845-154588845	pancreas	carcinoma; ductal_carcinoma	Substitution - coding silent
c.312G>A; p.S104S; 4:154588845-154588845	pancreas	carcinoma	Substitution - coding silent
c.2564C>T; p.A855V; 4:154584161-154584161	skin	malignant_melanoma	Substitution - Missense
c.2564C>T; p.A855V; 4:154584161-154584161	skin	malignant_melanoma	Substitution - Missense
c.2367C>A; p.D789E; 4:154584358-154584358	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.816A>T; p.G272G; 4:154586613-154586613	skin	malignant_melanoma	Substitution - coding silent
c.2560A>G; p.R854G; 4:154584165-154584165	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1695T>C; p.P565P; 4:154585734-154585734	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.81_82insT; p.L28fs*3; 4:154589535-154589536	liver	carcinoma	Insertion - Frameshift
c.1753A>T; p.S585C; 4:154585676-154585676	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1695T>C; p.P565P; 4:154585734-154585734	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.415G>A; p.E139K; 4:154587607-154587607	skin	malignant_melanoma	Substitution - Missense
c.533G>A; p.R178Q; 4:154586896-154586896	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.415G>A; p.E139K; 4:154587607-154587607	skin	malignant_melanoma	Substitution - Missense
c.533G>A; p.R178Q; 4:154586896-154586896	pituitary; craniopharyngeal_duct	craniopharyngioma; adamantinomatous	Substitution - Missense
c.415G>A; p.E139K; 4:154587607-154587607	skin	malignant_melanoma	Substitution - Missense
c.533G>A; p.R178Q; 4:154586896-154586896	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.415G>A; p.E139K; 4:154587607-154587607	skin; mucosal	malignant_melanoma	Substitution - Missense
c.898T>A; p.S300T; 4:154586531-154586531	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.331G>A; p.E111K; 4:154588826-154588826	skin	malignant_melanoma	Substitution - Missense
c.331G>A; p.E111K; 4:154588826-154588826	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.331G>A; p.E111K; 4:154588826-154588826	skin	malignant_melanoma	Substitution - Missense
c.2268C>A; p.S756S; 4:154584457-154584457	ovary	carcinoma; serous_carcinoma	Substitution - coding silent
c.1006T>C; p.S336P; 4:154586423-154586423	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.2285C>T; p.A762V; 4:154584440-154584440	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.2237C>A; p.S746Y; 4:154584488-154584488	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.821C>A; p.S274Y; 4:154586608-154586608	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1229G>A; p.W410*; 4:154586200-154586200	breast	carcinoma; lobular_carcinoma	Substitution - Nonsense
c.1622T>A; p.V541D; 4:154585807-154585807	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.885G>T; p.W295C; 4:154586544-154586544	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1976T>G; p.F659C; 4:154584749-154584749	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.569G>A; p.R190H; 4:154586860-154586860	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.2092A>C; p.S698R; 4:154584633-154584633	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1089C>T; p.G363G; 4:154586340-154586340	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.2227C>T; p.R743W; 4:154584498-154584498	prostate	carcinoma	Substitution - Missense
c.2038G>C; p.D680H; 4:154584687-154584687	breast	carcinoma	Substitution - Missense
c.2374G>A; p.A792T; 4:154584351-154584351	skin	malignant_melanoma	Substitution - Missense
c.1355G>T; p.G452V; 4:154586074-154586074	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.2386G>A; p.E796K; 4:154584339-154584339	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.1539_1540CC>TT; p.P514S; 4:154585889-154585890	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.238G>T; p.D80Y; 4:154588919-154588919	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.511G>A; p.V171M; 4:154586918-154586918	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1387A>C; p.K463Q; 4:154586042-154586042	prostate	carcinoma; adenocarcinoma	Substitution - Missense
c.849G>A; p.T283T; 4:154586580-154586580	skin	malignant_melanoma	Substitution - coding silent
c.531C>T; p.I177I; 4:154586898-154586898	skin	malignant_melanoma	Substitution - coding silent
c.2505T>G; p.Y835*; 4:154584220-154584220	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Nonsense
c.2111A>G; p.E704G; 4:154584614-154584614	pancreas	carcinoma	Substitution - Missense
c.332A>G; p.E111G; 4:154588825-154588825	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1817A>G; p.E606G; 4:154585612-154585612	bone	Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	Substitution - Missense
c.507G>A; p.L169L; 4:154587515-154587515	skin	malignant_melanoma	Substitution - coding silent
c.1822G>A; p.G608R; 4:154585607-154585607	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1710C>T; p.F570F; 4:154585719-154585719	skin	malignant_melanoma	Substitution - coding silent
c.1126G>A; p.E376K; 4:154586303-154586303	urinary_tract; bladder	carcinoma	Substitution - Missense
c.1126G>A; p.E376K; 4:154586303-154586303	urinary_tract; bladder	carcinoma; transitional_cell_carcinoma	Substitution - Missense
c.1126G>A; p.E376K; 4:154586303-154586303	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.2459T>G; p.I820S; 4:154584266-154584266	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.2443G>A; p.A815T; 4:154584282-154584282	breast	carcinoma; ductal_carcinoma	Substitution - Missense
c.439G>A; p.E147K; 4:154587583-154587583	skin	malignant_melanoma	Substitution - Missense
c.930T>C; p.P310P; 4:154586499-154586499	skin	malignant_melanoma	Substitution - coding silent
c.520G>A; p.D174N; 4:154586909-154586909	skin	malignant_melanoma	Substitution - Missense
c.1291G>A; p.E431K; 4:154586138-154586138	skin	malignant_melanoma	Substitution - Missense
c.2283T>A; p.T761T; 4:154584442-154584442	pancreas	carcinoid-endocrine_tumour	Substitution - coding silent
c.107G>T; p.G36V; 4:154589510-154589510	liver	carcinoma; hepatocellular_carcinoma	Substitution - Missense
c.2209T>C; p.Y737H; 4:154584516-154584516	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2228G>A; p.R743Q; 4:154584497-154584497	stomach	carcinoma; intestinal_adenocarcinoma	Substitution - Missense
c.1291G>A; p.E431K; 4:154586138-154586138	urinary_tract; bladder	carcinoma	Substitution - Missense
c.922C>T; p.R308*; 4:154586507-154586507	stomach	carcinoma; adenocarcinoma	Substitution - Nonsense
c.1729T>C; p.S577P; 4:154585700-154585700	prostate	carcinoma; adenocarcinoma	Substitution - Missense
c.1980T>G; p.S660S; 4:154584745-154584745	bone	Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	Substitution - coding silent
c.1101C>T; p.R367R; 4:154586328-154586328	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.1101C>T; p.R367R; 4:154586328-154586328	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.2234G>T; p.G745V; 4:154584491-154584491	urinary_tract; bladder	carcinoma	Substitution - Missense
c.145G>A; p.D49N; 4:154589472-154589472	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.214G>T; p.G72W; 4:154588943-154588943	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.902G>A; p.G301E; 4:154586527-154586527	skin	malignant_melanoma	Substitution - Missense
c.1711C>A; p.P571T; 4:154585718-154585718	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2501C>T; p.P834L; 4:154584224-154584224	skin	malignant_melanoma	Substitution - Missense
c.2007G>T; p.L669F; 4:154584718-154584718	skin	malignant_melanoma	Substitution - Missense
c.848C>T; p.T283M; 4:154586581-154586581	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.1728T>G; p.S576S; 4:154585701-154585701	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.600G>C; p.Q200H; 4:154586829-154586829	breast	carcinoma	Substitution - Missense
c.815G>A; p.G272E; 4:154586614-154586614	skin	malignant_melanoma	Substitution - Missense
c.510+10T>A; p.?; 4:154587502-154587502	lung	carcinoma; squamous_cell_carcinoma	Unknown
c.1591G>A; p.G531S; 4:154585838-154585838	urinary_tract; bladder	carcinoma; transitional_cell_carcinoma	Substitution - Missense
c.309T>C; p.H103H; 4:154588848-154588848	prostate	carcinoma; adenocarcinoma	Substitution - coding silent
c.2286G>T; p.A762A; 4:154584439-154584439	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.1591G>A; p.G531S; 4:154585838-154585838	urinary_tract; bladder	carcinoma	Substitution - Missense
c.1782C>T; p.S594S; 4:154585647-154585647	oesophagus	carcinoma; adenocarcinoma	Substitution - coding silent
c.764C>T; p.P255L; 4:154586665-154586665	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.163T>A; p.C55S; 4:154589454-154589454	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.647G>A; p.R216K; 4:154586782-154586782	urinary_tract; bladder	carcinoma	Substitution - Missense
c.653G>T; p.R218M; 4:154586776-154586776	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1694C>A; p.P565H; 4:154585735-154585735	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.2221C>T; p.H741Y; 4:154584504-154584504	skin	malignant_melanoma	Substitution - Missense
c.2585C>A; p.P862H; 4:154584140-154584140	liver	carcinoma	Substitution - Missense
c.2585C>A; p.P862H; 4:154584140-154584140	liver	carcinoma	Substitution - Missense
c.1443A>C; p.E481D; 4:154585986-154585986	breast	carcinoma	Substitution - Missense
c.1302C>A; p.V434V; 4:154586127-154586127	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.1199C>T; p.S400F; 4:154586230-154586230	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1082A>G; p.N361S; 4:154586347-154586347	liver	carcinoma; hepatocellular_carcinoma	Substitution - Missense
c.1880_1881insA; p.V629fs*5; 4:154585548-154585549	liver	carcinoma	Insertion - Frameshift
c.61G>T; p.D21Y; 4:154589556-154589556	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.1704T>A; p.A568A; 4:154585725-154585725	liver	carcinoma	Substitution - coding silent
c.1704T>A; p.A568A; 4:154585725-154585725	liver	carcinoma	Substitution - coding silent
c.685G>C; p.V229L; 4:154586744-154586744	prostate	carcinoma	Substitution - Missense
c.1229G>T; p.W410L; 4:154586200-154586200	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1229G>T; p.W410L; 4:154586200-154586200	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1341G>A; p.E447E; 4:154586088-154586088	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1527C>T; p.F509F; 4:154585902-154585902	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.1527C>T; p.F509F; 4:154585902-154585902	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.986G>A; p.G329E; 4:154586443-154586443	skin	malignant_melanoma	Substitution - Missense
c.1697G>T; p.G566V; 4:154585732-154585732	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2265C>G; p.V755V; 4:154584460-154584460	liver	carcinoma	Substitution - coding silent
c.2265C>G; p.V755V; 4:154584460-154584460	liver	carcinoma	Substitution - coding silent
c.804G>A; p.E268E; 4:154586625-154586625	skin	malignant_melanoma	Substitution - coding silent
c.700C>G; p.P234A; 4:154586729-154586729	urinary_tract; bladder	carcinoma	Substitution - Missense
c.1587C>T; p.F529F; 4:154585842-154585842	skin	malignant_melanoma	Substitution - coding silent
c.1718G>A; p.R573H; 4:154585711-154585711	fallopian_tube	carcinoma; serous_carcinoma	Substitution - Missense
c.1718G>A; p.R573H; 4:154585711-154585711	bone	Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	Substitution - Missense
c.98G>A; p.G33D; 4:154589519-154589519	pancreas	carcinoma	Substitution - Missense
c.98G>A; p.G33D; 4:154589519-154589519	pancreas	carcinoma	Substitution - Missense
c.1587C>T; p.F529F; 4:154585842-154585842	skin	malignant_melanoma	Substitution - coding silent
c.1989C>T; p.C663C; 4:154584736-154584736	kidney	carcinoma; papillary_renal_cell_carcinoma	Substitution - coding silent
c.2129G>T; p.G710V; 4:154584596-154584596	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.901G>T; p.G301*; 4:154586528-154586528	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Nonsense
c.1766A>G; p.Y589C; 4:154585663-154585663	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.100G>A; p.V34M; 4:154589517-154589517	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1562A>T; p.D521V; 4:154585867-154585867	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.103C>T; p.R35C; 4:154589514-154589514	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.625G>T; p.A209S; 4:154586804-154586804	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.103C>T; p.R35C; 4:154589514-154589514	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.878G>T; p.G293V; 4:154586551-154586551	breast	carcinoma	Substitution - Missense
c.44G>A; p.G15D; 4:154590644-154590644	soft_tissue; striated_muscle	rhabdomyosarcoma	Substitution - Missense
c.44G>A; p.G15D; 4:154590644-154590644	soft_tissue; striated_muscle	rhabdomyosarcoma; embryonal	Substitution - Missense
c.1163C>T; p.S388F; 4:154586266-154586266	skin	malignant_melanoma	Substitution - Missense
c.2096T>C; p.L699P; 4:154584629-154584629	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1036A>G; p.N346D; 4:154586393-154586393	central_nervous_system; brain	primitive_neuroectodermal_tumour-medulloblastoma	Substitution - Missense
c.2508G>T; p.E836D; 4:154584217-154584217	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.888C>A; p.N296K; 4:154586541-154586541	lung	carcinoma; small_cell_carcinoma	Substitution - Missense
c.1643G>T; p.G548V; 4:154585786-154585786	urinary_tract; bladder	carcinoma	Substitution - Missense
c.104G>A; p.R35H; 4:154589513-154589513	pancreas	carcinoma; ductal_carcinoma	Substitution - Missense
c.1643G>T; p.G548V; 4:154585786-154585786	urinary_tract; bladder	carcinoma; transitional_cell_carcinoma	Substitution - Missense
c.104G>A; p.R35H; 4:154589513-154589513	pancreas	carcinoma	Substitution - Missense
c.2311G>A; p.V771I; 4:154584414-154584414	prostate	carcinoma; adenocarcinoma	Substitution - Missense
c.1284C>A; p.Y428*; 4:154586145-154586145	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Nonsense
c.784G>A; p.E262K; 4:154586645-154586645	skin	malignant_melanoma	Substitution - Missense
c.1480G>A; p.A494T; 4:154585949-154585949	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2490G>A; p.R830R; 4:154584235-154584235	skin	malignant_melanoma	Substitution - coding silent
c.1247T>G; p.V416G; 4:154586182-154586182	breast	carcinoma	Substitution - Missense
c.1379C>T; p.S460L; 4:154586050-154586050	skin	malignant_melanoma	Substitution - Missense
c.1518G>A; p.L506L; 4:154585911-154585911	oesophagus	carcinoma; adenocarcinoma	Substitution - coding silent
c.1209G>A; p.A403A; 4:154586220-154586220	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.1209G>A; p.A403A; 4:154586220-154586220	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1209G>A; p.A403A; 4:154586220-154586220	prostate	carcinoma	Substitution - coding silent
c.1207G>A; p.A403T; 4:154586222-154586222	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1207G>A; p.A403T; 4:154586222-154586222	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.617A>T; p.Q206L; 4:154586812-154586812	liver	carcinoma; hepatocellular_carcinoma	Substitution - Missense
c.402G>T; p.L134L; 4:154587620-154587620	ovary	carcinoma; serous_carcinoma	Substitution - coding silent
c.151G>T; p.D51Y; 4:154589466-154589466	skin	malignant_melanoma	Substitution - Missense
c.232A>C; p.N78H; 4:154588925-154588925	liver	carcinoma	Substitution - Missense
c.430A>T; p.K144*; 4:154587592-154587592	lung; right_lower_lobe	carcinoma; adenocarcinoma	Substitution - Nonsense
c.397G>A; p.D133N; 4:154587625-154587625	skin	malignant_melanoma	Substitution - Missense
c.305C>A; p.S102Y; 4:154588852-154588852	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.2534C>T; p.S845F; 4:154584191-154584191	skin	malignant_melanoma	Substitution - Missense
c.2534C>T; p.S845F; 4:154584191-154584191	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2534C>T; p.S845F; 4:154584191-154584191	skin	malignant_melanoma	Substitution - Missense
c.305C>A; p.S102Y; 4:154588852-154588852	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1541C>G; p.P514R; 4:154585888-154585888	bone; pelvis	chondrosarcoma	Substitution - Missense
c.2103C>T; p.D701D; 4:154584622-154584622	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.532C>T; p.R178*; 4:154586897-154586897	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Nonsense
c.711T>G; p.F237L; 4:154586718-154586718	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1901A>G; p.D634G; 4:154584824-154584824	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.532C>T; p.R178*; 4:154586897-154586897	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Nonsense
c.2474G>A; p.G825D; 4:154584251-154584251	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2364T>A; p.F788L; 4:154584361-154584361	liver	carcinoma	Substitution - Missense
c.1975T>G; p.F659V; 4:154584750-154584750	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.950G>A; p.G317E; 4:154586479-154586479	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1112G>T; p.G371V; 4:154586317-154586317	lung; right_lower_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.574G>A; p.V192I; 4:154586855-154586855	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.2096T>A; p.L699Q; 4:154584629-154584629	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.2145C>A; p.H715Q; 4:154584580-154584580	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.2334C>A; p.T778T; 4:154584391-154584391	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.1032T>A; p.T344T; 4:154586397-154586397	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1046C>T; p.P349L; 4:154586383-154586383	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.391T>C; p.S131P; 4:154587631-154587631	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.391T>C; p.S131P; 4:154587631-154587631	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.480A>G; p.R160R; 4:154587542-154587542	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.1201G>T; p.G401W; 4:154586228-154586228	autonomic_ganglia	neuroblastoma	Substitution - Missense
c.2179G>A; p.E727K; 4:154584546-154584546	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.311C>T; p.S104L; 4:154588846-154588846	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1091G>C; p.S364T; 4:154586338-154586338	bone	Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	Substitution - Missense
c.1718G>T; p.R573L; 4:154585711-154585711	bone; tibia	chondrosarcoma	Substitution - Missense
c.2570G>A; p.R857H; 4:154584155-154584155	stomach	carcinoma; diffuse_adenocarcinoma	Substitution - Missense
c.311C>T; p.S104L; 4:154588846-154588846	skin	malignant_melanoma	Substitution - Missense
c.311C>T; p.S104L; 4:154588846-154588846	skin	malignant_melanoma	Substitution - Missense
c.765G>A; p.P255P; 4:154586664-154586664	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.311C>T; p.S104L; 4:154588846-154588846	skin	malignant_melanoma	Substitution - Missense
c.2570G>A; p.R857H; 4:154584155-154584155	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.765G>A; p.P255P; 4:154586664-154586664	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.2119T>C; p.F707L; 4:154584606-154584606	prostate	carcinoma	Substitution - Missense
c.991A>G; p.T331A; 4:154586438-154586438	prostate	carcinoma; adenocarcinoma	Substitution - Missense
c.991A>G; p.T331A; 4:154586438-154586438	prostate	carcinoma; adenocarcinoma	Substitution - Missense
c.1883C>A; p.P628H; 4:154585546-154585546	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1693C>T; p.P565S; 4:154585736-154585736	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.2088C>T; p.F696F; 4:154584637-154584637	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.1832C>A; p.A611D; 4:154585597-154585597	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1212G>T; p.R404S; 4:154586217-154586217	lung	carcinoma; small_cell_carcinoma	Substitution - Missense

Annotation category 5

Basic annotation

Literature evidence

Expression

Somatic mutation

Network

ceRNA

Gene information

COSMIC somatic mutation