Cancer metastasis database

Annotation category 5

Gene information

Gene ID 2217
Symbol

FCGRT

Synonymous

FCRN|alpha-chain

Full name

Fc fragment of IgG, receptor, transporter, alpha

Gene description

FcRn alpha chain|IgG Fc fragment receptor transporter alpha chain|IgG receptor FcRn large subunit p51|immunoglobulin receptor, intestinal, heavy chain|major histocompatibility complex class I-like Fc receptor|neonatal Fc receptor|neonatal Fc-receptor for

Cytoband

19q13.3

Gene type

protein-coding

Synonymous

MIM:601437; HGNC:HGNC:3621; Ensembl:ENSG00000104870; HPRD:03257; Vega:OTTHUMG00000183155

COSMIC somatic mutation

Mutation (CDS; AA; Chr)

Site

Histology

Mutation Type

c.621G>A; p.L207L; 19:49524526-49524526

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.204G>A; p.A68A; 19:49514012-49514012

 large_intestinecarcinoma; adenocarcinomaSubstitution - coding silent

c.1093G>A; p.A365T; 19:49526114-49526114

 haematopoietic_and_lymphoid_tissuelymphoid_neoplasm; acute_lymphoblastic_leukaemiaSubstitution - Missense

c.328C>T; p.P110S; 19:49514213-49514213

 prostatecarcinoma; adenocarcinomaSubstitution - Missense

c.779C>T; p.S260L; 19:49524684-49524684

 oesophaguscarcinoma; adenocarcinomaSubstitution - Missense

c.305T>A; p.F102Y; 19:49514113-49514113

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - Missense

c.525C>T; p.L175L; 19:49514410-49514410

 skinmalignant_melanomaSubstitution - coding silent

c.321delA; p.G109fs*27; 19:49514129-49514129

 large_intestinecarcinoma; adenocarcinomaDeletion - Frameshift

c.396G>C; p.K132N; 19:49514281-49514281

 prostatecarcinomaSubstitution - Missense

c.916G>A; p.G306S; 19:49525501-49525501

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Missense

c.295C>T; p.L99L; 19:49514103-49514103

 breastcarcinomaSubstitution - coding silent

c.837C>T; p.H279H; 19:49524742-49524742

 thyroidother; neoplasmSubstitution - coding silent

c.125C>T; p.P42L; 19:49513933-49513933

 oesophagus; upper_thirdcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.55C>T; p.P19S; 19:49513455-49513455

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.680A>G; p.Y227C; 19:49524585-49524585

 lung; right_upper_lobecarcinoma; adenocarcinomaSubstitution - Missense

c.129G>T; p.G43G; 19:49513937-49513937

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - coding silent

c.316G>C; p.G106R; 19:49514124-49514124

 boneEwings_sarcoma-peripheral_primitive_neuroectodermal_tumourSubstitution - Missense

c.1060G>A; p.D354N; 19:49526081-49526081

 urinary_tract; bladdercarcinomaSubstitution - Missense

c.616C>T; p.R206C; 19:49524521-49524521

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.849G>A; p.A283A; 19:49524754-49524754

 large_intestinecarcinoma; adenocarcinomaSubstitution - coding silent

c.724G>A; p.A242T; 19:49524629-49524629

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.315delG; p.G107fs*29; 19:49514123-49514123

 large_intestine; coloncarcinoma; adenocarcinomaDeletion - Frameshift

c.487C>T; p.R163W; 19:49514372-49514372

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.591G>A; p.L197L; 19:49514476-49514476

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - coding silent

c.555C>T; p.R185R; 19:49514440-49514440

 stomachcarcinoma; adenocarcinomaSubstitution - coding silent

c.640C>T; p.P214S; 19:49524545-49524545

 skinmalignant_melanomaSubstitution - Missense

c.502G>A; p.D168N; 19:49514387-49514387

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.582C>T; p.R194R; 19:49514467-49514467

 breastcarcinomaSubstitution - coding silent

c.582C>T; p.R194R; 19:49514467-49514467

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.356G>T; p.C119F; 19:49514241-49514241

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Missense

c.466G>A; p.E156K; 19:49514351-49514351

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.739G>A; p.G247S; 19:49524644-49524644

 skinmalignant_melanomaSubstitution - Missense

c.890C>T; p.S297F; 19:49525475-49525475

 skin; extremitymalignant_melanomaSubstitution - Missense

c.370G>A; p.D124N; 19:49514255-49514255

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.892G>A; p.V298M; 19:49525477-49525477

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.85T>A; p.S29T; 19:49513893-49513893

 breastcarcinomaSubstitution - Missense

c.75A>C; p.E25D; 19:49513883-49513883

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - Missense

c.762C>T; p.D254D; 19:49524667-49524667

 pancreascarcinomaSubstitution - coding silent

c.693G>A; p.L231L; 19:49524598-49524598

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.1068G>T; p.K356N; 19:49526089-49526089

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.1068G>T; p.K356N; 19:49526089-49526089

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.1068G>T; p.K356N; 19:49526089-49526089

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.547C>T; p.P183S; 19:49514432-49514432

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.248A>G; p.Y83C; 19:49514056-49514056

 kidneycarcinoma; papillary_renal_cell_carcinomaSubstitution - Missense

c.84C>T; p.L28L; 19:49513892-49513892

 urinary_tract; bladdercarcinomaSubstitution - coding silent

c.513C>T; p.A171A; 19:49514398-49514398

 lungcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.180C>G; p.S60R; 19:49513988-49513988

 ovarycarcinoma; serous_carcinomaSubstitution - Missense

c.76A>G; p.S26G; 19:49513884-49513884

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - Missense

c.321A>G; p.G107G; 19:49514129-49514129

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.243C>A; p.S81S; 19:49514051-49514051

 livercarcinomaSubstitution - coding silent

c.243C>A; p.S81S; 19:49514051-49514051

 livercarcinomaSubstitution - coding silent

c.938C>T; p.A313V; 19:49525523-49525523

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.193C>T; p.R65W; 19:49514001-49514001

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.118C>G; p.P40A; 19:49513926-49513926

 thyroidcarcinomaSubstitution - Missense

c.118C>G; p.P40A; 19:49513926-49513926

 thyroidcarcinomaSubstitution - Missense

c.782C>T; p.S261L; 19:49524687-49524687

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.782C>T; p.S261L; 19:49524687-49524687

 skinmalignant_melanomaSubstitution - Missense

c.1006C>T; p.R336C; 19:49526027-49526027

 skinmalignant_melanomaSubstitution - Missense

c.783G>A; p.S261S; 19:49524688-49524688

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - coding silent

c.877C>G; p.P293A; 19:49525462-49525462

 prostatecarcinoma; adenocarcinomaSubstitution - Missense

c.314_315insG; p.G109fs*12; 19:49514122-49514123

 large_intestine; coloncarcinoma; adenocarcinomaInsertion - Frameshift

c.617G>A; p.R206H; 19:49524522-49524522

 breastcarcinomaSubstitution - Missense