lung cancer gene and literature database Home

Annotation category 5

Basic annotation
Ontology and pathways
Literature evidence
Curated literatures
Expression
Gene expression chart
Somatic mutation
COSMIC and TCGA mutations
Network
Gene interaction
ceRNA
Gene-related ceRNA

Gene information

Gene ID	2050
Symbol	EPHB4
Synonymous	HTK\|MYK1\|TYRO11
Full name	EPH receptor B4
Gene description	ephrin receptor EphB4\|ephrin type-B receptor 4\|hepatoma transmembrane kinase\|soluble EPHB4 variant 1\|soluble EPHB4 variant 2\|soluble EPHB4 variant 3\|tyrosine-protein kinase TYRO11\|tyrosine-protein kinase receptor HTK
Cytoband	7q22
Gene type	protein-coding
Synonymous	MIM:600011; HGNC:HGNC:3395; Ensembl:ENSG00000196411; HPRD:02481; Vega:OTTHUMG00000157040

COSMIC somatic mutation

Mutation (CDS; AA; Chr)	Site	Histology	Mutation Type
c.2593C>T; p.P865S; 7:100805586-100805586	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2014G>A; p.E672K; 7:100812851-100812851	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.943C>T; p.P315S; 7:100820162-100820162	skin	malignant_melanoma	Substitution - Missense
c.809C>T; p.A270V; 7:100820296-100820296	lung	carcinoma; small_cell_carcinoma	Substitution - Missense
c.2108C>T; p.S703F; 7:100812757-100812757	skin	malignant_melanoma	Substitution - Missense
c.2458C>T; p.P820S; 7:100806446-100806446	skin	malignant_melanoma	Substitution - Missense
c.1401C>T; p.Y467Y; 7:100818541-100818541	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.1414C>T; p.H472Y; 7:100818528-100818528	skin; arm	malignant_melanoma	Substitution - Missense
c.377T>G; p.L126R; 7:100823678-100823678	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1486G>T; p.G496W; 7:100817294-100817294	lung	carcinoma; small_cell_carcinoma	Substitution - Missense
c.1296G>T; p.E432D; 7:100819558-100819558	lung	carcinoma; large_cell_carcinoma	Substitution - Missense
c.794A>T; p.N265I; 7:100822285-100822285	liver	carcinoma; hepatocellular_carcinoma	Substitution - Missense
c.794A>T; p.N265I; 7:100822285-100822285	liver	carcinoma	Substitution - Missense
c.1829T>C; p.I610T; 7:100813136-100813136	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.2466G>A; p.W822*; 7:100806438-100806438	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Nonsense
c.2466G>A; p.W822*; 7:100806438-100806438	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Nonsense
c.359C>T; p.A120V; 7:100823696-100823696	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1292G>A; p.R431Q; 7:100819562-100819562	breast	carcinoma; ER-PR-positive_carcinoma	Substitution - Missense
c.412-1G>T; p.?; 7:100822668-100822668	skin; head_neck	carcinoma; squamous_cell_carcinoma	Unknown
c.1298-6T>G; p.?; 7:100818650-100818650	liver	carcinoma	Unknown
c.360G>A; p.A120A; 7:100823695-100823695	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.1974G>A; p.R658R; 7:100812891-100812891	pancreas	carcinoma	Substitution - coding silent
c.2565C>T; p.D855D; 7:100805614-100805614	lung; right_lower_lobe	carcinoma; adenocarcinoma	Substitution - coding silent
c.2688C>T; p.H896H; 7:100805312-100805312	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.2472G>A; p.M824I; 7:100806432-100806432	urinary_tract; bladder	carcinoma	Substitution - Missense
c.840A>T; p.S280S; 7:100820265-100820265	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.1037C>T; p.P346L; 7:100819817-100819817	skin	malignant_melanoma	Substitution - Missense
c.1037C>T; p.P346L; 7:100819817-100819817	skin	malignant_melanoma	Substitution - Missense
c.1037C>T; p.P346L; 7:100819817-100819817	skin	malignant_melanoma	Substitution - Missense
c.1674C>T; p.V558V; 7:100813936-100813936	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.2484C>T; p.D828D; 7:100806420-100806420	stomach	adenocarcinoma	Substitution - coding silent
c.2378_2379CC>TT; p.A793V; 7:100806525-100806526	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.998G>A; p.R333H; 7:100819856-100819856	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1759A>G; p.T587A; 7:100813206-100813206	prostate	carcinoma	Substitution - Missense
c.1887G>A; p.V629V; 7:100812978-100812978	ovary	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.1887G>A; p.V629V; 7:100812978-100812978	ovary	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.2880A>C; p.K960N; 7:100803545-100803545	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.1918_1920delAAG; p.K640delK; 7:100812945-100812947	oesophagus; lower_third	carcinoma; adenocarcinoma	Deletion - In frame
c.2571G>A; p.W857*; 7:100805608-100805608	lung	carcinoma; squamous_cell_carcinoma	Substitution - Nonsense
c.1919A>C; p.K640T; 7:100812946-100812946	skin	malignant_melanoma	Substitution - Missense
c.1945C>A; p.L649M; 7:100812920-100812920	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1834G>A; p.V612I; 7:100813131-100813131	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; peripheral_T_cell_lymphoma_unspecified	Substitution - Missense
c.2397C>T; p.S799S; 7:100806507-100806507	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.2366C>T; p.P789L; 7:100806538-100806538	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.820G>T; p.G274C; 7:100820285-100820285	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.814G>T; p.A272S; 7:100820291-100820291	liver	carcinoma; hepatocellular_carcinoma	Substitution - Missense
c.2750G>A; p.R917Q; 7:100805250-100805250	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.2196C>G; p.A732A; 7:100807503-100807503	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - coding silent
c.2000T>C; p.I667T; 7:100812865-100812865	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.2324C>T; p.T775M; 7:100807375-100807375	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1216G>A; p.V406I; 7:100819638-100819638	breast	carcinoma	Substitution - Missense
c.2324C>T; p.T775M; 7:100807375-100807375	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1480C>T; p.L494L; 7:100817300-100817300	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.1422G>C; p.K474N; 7:100818520-100818520	prostate	carcinoma	Substitution - Missense
c.537G>A; p.Q179Q; 7:100822542-100822542	skin	malignant_melanoma	Substitution - coding silent
c.2767A>G; p.R923G; 7:100805233-100805233	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.2202G>C; p.M734I; 7:100807497-100807497	oesophagus	carcinoma	Substitution - Missense
c.1620G>C; p.L540L; 7:100813990-100813990	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - coding silent
c.296C>T; p.S99F; 7:100823759-100823759	skin	malignant_melanoma	Substitution - Missense
c.1402G>A; p.E468K; 7:100818540-100818540	skin	malignant_melanoma	Substitution - Missense
c.1527G>A; p.A509A; 7:100817253-100817253	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.27G>A; p.W9*; 7:100827004-100827004	large_intestine	carcinoma; adenocarcinoma	Substitution - Nonsense
c.1989C>T; p.S663S; 7:100812876-100812876	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.2116C>T; p.R706W; 7:100812749-100812749	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.915C>T; p.R305R; 7:100820190-100820190	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - coding silent
c.1724C>T; p.S575L; 7:100813684-100813684	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.1331G>A; p.R444Q; 7:100818611-100818611	breast	carcinoma	Substitution - Missense
c.1891C>T; p.R631W; 7:100812974-100812974	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.2953C>A; p.P985T; 7:100803472-100803472	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.786T>A; p.A262A; 7:100822293-100822293	liver	carcinoma; hepatocellular_carcinoma	Substitution - coding silent
c.786T>A; p.A262A; 7:100822293-100822293	liver	carcinoma	Substitution - coding silent
c.2463C>T; p.Y821Y; 7:100806441-100806441	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.2590C>T; p.R864W; 7:100805589-100805589	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.820G>A; p.G274S; 7:100820285-100820285	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.2883C>A; p.I961I; 7:100803542-100803542	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.1298-1G>C; p.?; 7:100818645-100818645	stomach	carcinoma; adenocarcinoma	Unknown
c.2067C>T; p.V689V; 7:100812798-100812798	skin	malignant_melanoma	Substitution - coding silent
c.2523G>A; p.P841P; 7:100805656-100805656	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.944C>T; p.P315L; 7:100820161-100820161	skin	malignant_melanoma	Substitution - Missense
c.944C>T; p.P315L; 7:100820161-100820161	skin	malignant_melanoma	Substitution - Missense
c.2666G>A; p.R889Q; 7:100805513-100805513	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.2666G>A; p.R889Q; 7:100805513-100805513	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2128G>A; p.G710R; 7:100807571-100807571	skin	malignant_melanoma	Substitution - Missense
c.1083C>T; p.C361C; 7:100819771-100819771	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.2383C>T; p.R795W; 7:100806521-100806521	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.313C>T; p.R105C; 7:100823742-100823742	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1412A>G; p.Y471C; 7:100818530-100818530	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.901G>A; p.V301I; 7:100820204-100820204	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.367G>A; p.A123T; 7:100823688-100823688	urinary_tract; bladder	carcinoma	Substitution - Missense
c.367G>A; p.A123T; 7:100823688-100823688	urinary_tract; bladder	carcinoma; transitional_cell_carcinoma	Substitution - Missense
c.1626G>C; p.A542A; 7:100813984-100813984	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.1760C>T; p.T587I; 7:100813205-100813205	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.494G>A; p.R165H; 7:100822585-100822585	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.945C>T; p.P315P; 7:100820160-100820160	skin	malignant_melanoma	Substitution - coding silent
c.193C>A; p.R65S; 7:100823862-100823862	oesophagus; middle_third	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.930G>T; p.R310R; 7:100820175-100820175	liver	carcinoma	Substitution - coding silent
c.930G>T; p.R310R; 7:100820175-100820175	liver	carcinoma	Substitution - coding silent
c.99G>T; p.V33V; 7:100824227-100824227	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - coding silent
c.1938C>G; p.I646M; 7:100812927-100812927	oesophagus	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.378C>T; p.L126L; 7:100823677-100823677	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1873G>A; p.E625K; 7:100812992-100812992	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.1798A>C; p.N600H; 7:100813167-100813167	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.2197G>A; p.E733K; 7:100807502-100807502	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.859C>G; p.P287A; 7:100820246-100820246	urinary_tract; bladder	carcinoma	Substitution - Missense
c.1241_1242CC>GA; p.S414*; 7:100819612-100819613	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Nonsense
c.600G>A; p.L200L; 7:100822479-100822479	breast	carcinoma	Substitution - coding silent
c.2543C>A; p.S848Y; 7:100805636-100805636	skin	malignant_melanoma	Substitution - Missense
c.180G>T; p.V60V; 7:100823875-100823875	central_nervous_system; brain	glioma	Substitution - coding silent
c.1330C>T; p.R444W; 7:100818612-100818612	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.2636G>A; p.R879Q; 7:100805543-100805543	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.2597G>A; p.R866H; 7:100805582-100805582	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.166C>T; p.R56C; 7:100823889-100823889	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.2597G>A; p.R866H; 7:100805582-100805582	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1603C>T; p.R535W; 7:100814007-100814007	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1773C>T; p.I591I; 7:100813192-100813192	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.1657C>T; p.L553L; 7:100813953-100813953	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.2301G>A; p.E767E; 7:100807398-100807398	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.1603C>T; p.R535W; 7:100814007-100814007	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1855G>A; p.E619K; 7:100813110-100813110	skin	malignant_melanoma	Substitution - Missense
c.267G>A; p.T89T; 7:100823788-100823788	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.1013C>T; p.S338F; 7:100819841-100819841	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.246C>A; p.G82G; 7:100823809-100823809	ovary	carcinoma; serous_carcinoma	Substitution - coding silent
c.1575G>A; p.Q525Q; 7:100817205-100817205	oesophagus	carcinoma; adenocarcinoma	Substitution - coding silent
c.2738G>T; p.G913V; 7:100805262-100805262	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1969C>G; p.Q657E; 7:100812896-100812896	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.742C>T; p.Q248*; 7:100822337-100822337	lung	carcinoma; adenocarcinoma	Substitution - Nonsense
c.1258G>A; p.V420I; 7:100819596-100819596	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2418C>T; p.Y806Y; 7:100806486-100806486	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.1233G>T; p.G411G; 7:100819621-100819621	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - coding silent
c.770C>T; p.P257L; 7:100822309-100822309	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2665C>T; p.R889W; 7:100805514-100805514	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.2665C>T; p.R889W; 7:100805514-100805514	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.2665C>T; p.R889W; 7:100805514-100805514	stomach	carcinoma; intestinal_adenocarcinoma	Substitution - Missense
c.1186C>T; p.L396L; 7:100819668-100819668	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1565A>G; p.H522R; 7:100817215-100817215	pancreas	carcinoma; acinar_carcinoma	Substitution - Missense
c.2665C>T; p.R889W; 7:100805514-100805514	stomach	adenocarcinoma	Substitution - Missense
c.524A>G; p.Y175C; 7:100822555-100822555	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1189C>T; p.R397C; 7:100819665-100819665	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.1357G>A; p.A453T; 7:100818585-100818585	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.1892G>A; p.R631Q; 7:100812973-100812973	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1706G>A; p.G569E; 7:100813702-100813702	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.1262C>A; p.P421Q; 7:100819592-100819592	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.592G>T; p.A198S; 7:100822487-100822487	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1968G>A; p.R656R; 7:100812897-100812897	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.1632G>A; p.T544T; 7:100813978-100813978	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1752A>G; p.G584G; 7:100813656-100813656	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1752A>G; p.G584G; 7:100813656-100813656	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - coding silent
c.1752A>G; p.G584G; 7:100813656-100813656	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - coding silent
c.1309G>A; p.V437M; 7:100818633-100818633	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1719A>G; p.E573E; 7:100813689-100813689	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1120G>T; p.G374W; 7:100819734-100819734	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.942C>A; p.D314E; 7:100820163-100820163	upper_aerodigestive_tract; mouth	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.503C>T; p.P168L; 7:100822576-100822576	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.942C>A; p.D314E; 7:100820163-100820163	upper_aerodigestive_tract; mouth	carcinoma	Substitution - Missense
c.1767C>T; p.V589V; 7:100813198-100813198	urinary_tract; bladder	carcinoma	Substitution - coding silent
c.269T>C; p.L90P; 7:100823786-100823786	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.687C>T; p.P229P; 7:100822392-100822392	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.1751G>A; p.G584E; 7:100813657-100813657	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.1099G>A; p.G367R; 7:100819755-100819755	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.2595C>T; p.P865P; 7:100805584-100805584	skin	malignant_melanoma	Substitution - coding silent
c.128A>T; p.E43V; 7:100823927-100823927	ovary	carcinoma	Substitution - Missense
c.2215C>T; p.R739*; 7:100807484-100807484	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Nonsense
c.369C>A; p.A123A; 7:100823686-100823686	thyroid	other; neoplasm	Substitution - coding silent
c.2280C>T; p.G760G; 7:100807419-100807419	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.2186G>A; p.R729Q; 7:100807513-100807513	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.2065G>A; p.V689I; 7:100812800-100812800	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.2065G>A; p.V689I; 7:100812800-100812800	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.2151C>T; p.L717L; 7:100807548-100807548	skin	malignant_melanoma	Substitution - coding silent
c.1749C>T; p.I583I; 7:100813659-100813659	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.493C>T; p.R165C; 7:100822586-100822586	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.935G>T; p.R312L; 7:100820170-100820170	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.913C>A; p.R305S; 7:100820192-100820192	kidney	carcinoma; papillary_renal_cell_carcinoma	Substitution - Missense
c.361G>T; p.D121Y; 7:100823694-100823694	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.2484+1G>A; p.?; 7:100806419-100806419	lung	carcinoma; squamous_cell_carcinoma	Unknown
c.2603C>T; p.P868L; 7:100805576-100805576	skin	malignant_melanoma	Substitution - Missense
c.2343G>C; p.K781N; 7:100806561-100806561	oesophagus	carcinoma	Substitution - Missense
c.683T>C; p.V228A; 7:100822396-100822396	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1530C>T; p.R510R; 7:100817250-100817250	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.1530C>T; p.R510R; 7:100817250-100817250	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.571C>T; p.H191Y; 7:100822508-100822508	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.2398G>A; p.A800T; 7:100806506-100806506	stomach	carcinoma	Substitution - Missense
c.2773G>A; p.E925K; 7:100805227-100805227	skin	malignant_melanoma	Substitution - Missense
c.1301C>T; p.P434L; 7:100818641-100818641	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.827T>G; p.F276C; 7:100820278-100820278	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.1662G>A; p.V554V; 7:100813948-100813948	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - coding silent
c.1830C>T; p.I610I; 7:100813135-100813135	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.1986G>A; p.L662L; 7:100812879-100812879	breast	carcinoma	Substitution - coding silent
c.1213G>C; p.E405Q; 7:100819641-100819641	urinary_tract; bladder	carcinoma	Substitution - Missense
c.1095A>G; p.R365R; 7:100819759-100819759	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.106C>T; p.P36S; 7:100824220-100824220	skin	malignant_melanoma	Substitution - Missense
c.616C>T; p.R206*; 7:100822463-100822463	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Nonsense
c.1659G>C; p.L553L; 7:100813951-100813951	ovary	carcinoma; serous_carcinoma	Substitution - coding silent
c.1079G>A; p.R360H; 7:100819775-100819775	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.935G>A; p.R312H; 7:100820170-100820170	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.935G>A; p.R312H; 7:100820170-100820170	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.2154G>T; p.V718V; 7:100807545-100807545	oesophagus	carcinoma; adenocarcinoma	Substitution - coding silent
c.1261C>T; p.P421S; 7:100819593-100819593	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2166G>A; p.R722R; 7:100807533-100807533	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - coding silent
c.1159G>A; p.V387M; 7:100819695-100819695	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.118G>A; p.G40R; 7:100824208-100824208	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.444G>A; p.R148R; 7:100822635-100822635	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.2177C>T; p.S726L; 7:100807522-100807522	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2064C>A; p.P688P; 7:100812801-100812801	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.2064C>A; p.P688P; 7:100812801-100812801	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.2272G>C; p.D758H; 7:100807427-100807427	breast	carcinoma	Substitution - Missense
c.1676C>T; p.A559V; 7:100813934-100813934	breast	carcinoma	Substitution - Missense
c.2209G>A; p.V737I; 7:100807490-100807490	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1545C>T; p.Y515Y; 7:100817235-100817235	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1545C>T; p.Y515Y; 7:100817235-100817235	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; peripheral_T_cell_lymphoma_unspecified	Substitution - coding silent
c.947G>A; p.R316Q; 7:100820158-100820158	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1150delC; p.R384fs*26; 7:100819704-100819704	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.2949_2950insACCG; p.A984fs*>6; 7:100803475-100803476	endometrium	carcinoma; endometrioid_carcinoma	Insertion - Frameshift

Annotation category 5

Basic annotation

Literature evidence

Expression

Somatic mutation

Network

ceRNA

Gene information

COSMIC somatic mutation