Cancer metastasis database

Annotation category 5

Gene information

Gene ID 203245
Symbol

NAIF1

Synonymous

C9orf90|bA379C10.2

Full name

nuclear apoptosis inducing factor 1

Gene description

nuclear apoptosis-inducing factor 1

Cytoband

9q34.11

Gene type

protein-coding

Synonymous

MIM:610673; HGNC:HGNC:25446; Ensembl:ENSG00000171169; HPRD:12987; Vega:OTTHUMG00000020727

COSMIC somatic mutation

Mutation (CDS; AA; Chr)

Site

Histology

Mutation Type

c.125C>T; p.A42V; 9:128066977-128066977

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.814G>T; p.A272S; 9:128063598-128063598

 livercarcinoma; hepatocellular_carcinomaSubstitution - Missense

c.178A>C; p.T60P; 9:128066924-128066924

 haematopoietic_and_lymphoid_tissuehaematopoietic_neoplasm; acute_myeloid_leukaemiaSubstitution - Missense

c.701G>A; p.R234Q; 9:128063711-128063711

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.318delG; p.P107fs*14; 9:128066784-128066784

 large_intestine; coloncarcinoma; adenocarcinomaDeletion - Frameshift

c.318delG; p.P107fs*14; 9:128066784-128066784

 large_intestinecarcinoma; adenocarcinomaDeletion - Frameshift

c.150C>T; p.G50G; 9:128066952-128066952

 lungcarcinoma; adenocarcinomaSubstitution - coding silent

c.469C>A; p.P157T; 9:128066633-128066633

 ovaryother; neoplasmSubstitution - Missense

c.897C>T; p.Y299Y; 9:128063515-128063515

 lungcarcinoma; adenocarcinomaSubstitution - coding silent

c.927_928insC; p.A310fs*3; 9:128063484-128063485

 skinmalignant_melanomaInsertion - Frameshift

c.927_928insC; p.A310fs*3; 9:128063484-128063485

 skinmalignant_melanomaInsertion - Frameshift

c.199G>A; p.E67K; 9:128066903-128066903

 upper_aerodigestive_tract; mouthcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.210G>T; p.K70N; 9:128066892-128066892

 urinary_tract; bladdercarcinoma; transitional_cell_carcinomaSubstitution - Missense

c.378C>T; p.T126T; 9:128066724-128066724

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.6C>T; p.A2A; 9:128067096-128067096

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.644C>T; p.P215L; 9:128063768-128063768

 oesophagus; lower_thirdcarcinoma; adenocarcinomaSubstitution - Missense

c.167A>G; p.N56S; 9:128066935-128066935

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.850G>A; p.V284I; 9:128063562-128063562

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.869G>A; p.R290Q; 9:128063543-128063543

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.475G>A; p.A159T; 9:128066627-128066627

 skinmalignant_melanomaSubstitution - Missense

c.475G>A; p.A159T; 9:128066627-128066627

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.109G>A; p.A37T; 9:128066993-128066993

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.967G>A; p.D323N; 9:128063445-128063445

 breastcarcinomaSubstitution - Missense

c.184C>T; p.R62C; 9:128066918-128066918

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Missense

c.36C>A; p.F12L; 9:128067066-128067066

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - Missense

c.284C>T; p.A95V; 9:128066818-128066818

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.293C>T; p.P98L; 9:128066809-128066809

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.808C>T; p.R270C; 9:128063604-128063604

 haematopoietic_and_lymphoid_tissuelymphoid_neoplasm; chronic_lymphocytic_leukaemia-small_lymphocytic_lymphomaSubstitution - Missense

c.582A>G; p.P194P; 9:128063830-128063830

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.679G>A; p.A227T; 9:128063733-128063733

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.679G>A; p.A227T; 9:128063733-128063733

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.964C>T; p.P322S; 9:128063448-128063448

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.485C>T; p.A162V; 9:128066617-128066617

 skinmalignant_melanomaSubstitution - Missense

c.81G>C; p.K27N; 9:128067021-128067021

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.768G>A; p.M256I; 9:128063644-128063644

 lung; right_upper_lobecarcinoma; adenocarcinomaSubstitution - Missense

c.342T>C; p.G114G; 9:128066760-128066760

 thyroidother; neoplasmSubstitution - coding silent

c.99C>G; p.N33K; 9:128067003-128067003

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.330C>T; p.G110G; 9:128066772-128066772

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.889C>T; p.R297C; 9:128063523-128063523

 breastcarcinomaSubstitution - Missense

c.227A>T; p.K76M; 9:128066875-128066875

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.817C>T; p.Q273*; 9:128063595-128063595

 skinmalignant_melanomaSubstitution - Nonsense

c.632C>T; p.T211M; 9:128063780-128063780

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.525C>A; p.T175T; 9:128063887-128063887

 pancreascarcinoid-endocrine_tumourSubstitution - coding silent

c.513_514CC>TT; p.P172S; 9:128063898-128063899

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.62T>C; p.V21A; 9:128067040-128067040

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.822C>A; p.A274A; 9:128063590-128063590

 breastcarcinomaSubstitution - coding silent

c.132G>C; p.K44N; 9:128066970-128066970

 breastcarcinomaSubstitution - Missense

c.54G>A; p.E18E; 9:128067048-128067048

 urinary_tract; bladdercarcinomaSubstitution - coding silent

c.331G>A; p.G111S; 9:128066771-128066771

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.772C>T; p.R258C; 9:128063640-128063640

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.835C>T; p.Q279*; 9:128063577-128063577

 stomachcarcinoma; adenocarcinomaSubstitution - Nonsense

c.924C>T; p.A308A; 9:128063488-128063488

 skinmalignant_melanomaSubstitution - coding silent

c.628G>C; p.D210H; 9:128063784-128063784

 breastcarcinomaSubstitution - Missense

c.231C>T; p.T77T; 9:128066871-128066871

 stomachcarcinoma; adenocarcinomaSubstitution - coding silent

c.961C>A; p.Q321K; 9:128063451-128063451

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.943C>T; p.Q315*; 9:128063469-128063469

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Nonsense

c.604G>A; p.V202M; 9:128063808-128063808

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.818A>T; p.Q273L; 9:128063594-128063594

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.346G>A; p.G116S; 9:128066756-128066756

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.776G>A; p.R259H; 9:128063636-128063636

 central_nervous_system; brainprimitive_neuroectodermal_tumour-medulloblastomaSubstitution - Missense

c.679G>C; p.A227P; 9:128063733-128063733

 boneEwings_sarcoma-peripheral_primitive_neuroectodermal_tumourSubstitution - Missense

c.308G>C; p.G103A; 9:128066794-128066794

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.115G>T; p.V39L; 9:128066987-128066987

 lungcarcinoma; small_cell_carcinomaSubstitution - Missense

c.773G>A; p.R258H; 9:128063639-128063639

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - Missense