lung cancer gene and literature database Home

Annotation category 5

Basic annotation
Ontology and pathways
Literature evidence
Curated literatures
Expression
Gene expression chart
Somatic mutation
COSMIC and TCGA mutations
Network
Gene interaction
ceRNA
Gene-related ceRNA

Gene information

Gene ID	1758
Symbol	DMP1
Synonymous	ARHP\|ARHR\|DMP-1
Full name	dentin matrix acidic phosphoprotein 1
Gene description	dentin matrix protein 1
Cytoband	4q21
Gene type	protein-coding
Synonymous	MIM:600980; HGNC:HGNC:2932; Ensembl:ENSG00000152592; HPRD:02989; Vega:OTTHUMG00000130598

COSMIC somatic mutation

Mutation (CDS; AA; Chr)	Site	Histology	Mutation Type
c.205A>T; p.S69C; 4:87661983-87661983	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.205A>T; p.S69C; 4:87661983-87661983	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.543T>C; p.G181G; 4:87662321-87662321	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.1447A>C; p.N483H; 4:87663225-87663225	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.795G>A; p.R265R; 4:87662573-87662573	skin	malignant_melanoma	Substitution - coding silent
c.1223C>T; p.S408F; 4:87663001-87663001	pancreas	carcinoma	Substitution - Missense
c.29T>G; p.L10R; 4:87656521-87656521	pancreas	carcinoma	Substitution - Missense
c.204C>T; p.D68D; 4:87661982-87661982	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - coding silent
c.1153G>A; p.E385K; 4:87662931-87662931	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1153G>A; p.E385K; 4:87662931-87662931	breast	carcinoma	Substitution - Missense
c.241C>T; p.H81Y; 4:87662019-87662019	skin	malignant_melanoma	Substitution - Missense
c.918C>T; p.L306L; 4:87662696-87662696	oesophagus; lower_third	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.175G>C; p.E59Q; 4:87659470-87659470	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.1453G>A; p.E485K; 4:87663231-87663231	skin	malignant_melanoma	Substitution - Missense
c.1453G>A; p.E485K; 4:87663231-87663231	skin	malignant_melanoma	Substitution - Missense
c.579G>T; p.W193C; 4:87662357-87662357	pancreas	carcinoma	Substitution - Missense
c.579G>T; p.W193C; 4:87662357-87662357	pancreas	carcinoma	Substitution - Missense
c.579G>T; p.W193C; 4:87662357-87662357	pancreas	carcinoma	Substitution - Missense
c.579G>T; p.W193C; 4:87662357-87662357	pancreas	carcinoma; ductal_carcinoma	Substitution - Missense
c.542G>A; p.G181D; 4:87662320-87662320	skin	malignant_melanoma	Substitution - Missense
c.217G>T; p.E73*; 4:87661995-87661995	lung	carcinoma; adenocarcinoma	Substitution - Nonsense
c.217G>T; p.E73*; 4:87661995-87661995	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Nonsense
c.1040C>A; p.S347*; 4:87662818-87662818	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Nonsense
c.388G>A; p.G130R; 4:87662166-87662166	skin	malignant_melanoma	Substitution - Missense
c.745G>A; p.A249T; 4:87662523-87662523	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.292G>T; p.G98*; 4:87662070-87662070	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Nonsense
c.292G>T; p.G98*; 4:87662070-87662070	prostate	carcinoma	Substitution - Nonsense
c.452C>T; p.A151V; 4:87662230-87662230	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1219G>A; p.E407K; 4:87662997-87662997	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.292G>T; p.G98*; 4:87662070-87662070	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Nonsense
c.490G>C; p.E164Q; 4:87662268-87662268	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1094G>A; p.G365E; 4:87662872-87662872	skin; shoulder	malignant_melanoma	Substitution - Missense
c.1167G>A; p.S389S; 4:87662945-87662945	skin	malignant_melanoma	Substitution - coding silent
c.674G>A; p.S225N; 4:87662452-87662452	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.287G>A; p.G96E; 4:87662065-87662065	skin	malignant_melanoma	Substitution - Missense
c.302A>T; p.D101V; 4:87662080-87662080	autonomic_ganglia	neuroblastoma	Substitution - Missense
c.1066C>T; p.Q356*; 4:87662844-87662844	skin	malignant_melanoma	Substitution - Nonsense
c.734A>C; p.N245T; 4:87662512-87662512	central_nervous_system; brain	primitive_neuroectodermal_tumour-medulloblastoma	Substitution - Missense
c.962G>T; p.S321I; 4:87662740-87662740	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.734A>C; p.N245T; 4:87662512-87662512	central_nervous_system; brain	primitive_neuroectodermal_tumour-medulloblastoma; medullomyoblastoma	Substitution - Missense
c.1304C>G; p.S435C; 4:87663082-87663082	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.896G>A; p.S299N; 4:87662674-87662674	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1497A>C; p.K499N; 4:87663275-87663275	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1357G>A; p.D453N; 4:87663135-87663135	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.539G>A; p.G180E; 4:87662317-87662317	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.873C>G; p.V291V; 4:87662651-87662651	urinary_tract; bladder	carcinoma	Substitution - coding silent
c.873C>G; p.V291V; 4:87662651-87662651	urinary_tract; bladder	carcinoma; transitional_cell_carcinoma	Substitution - coding silent
c.1514A>T; p.D505V; 4:87663292-87663292	thyroid	carcinoma	Substitution - Missense
c.1240T>G; p.F414V; 4:87663018-87663018	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1332C>T; p.S444S; 4:87663110-87663110	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.613G>A; p.G205R; 4:87662391-87662391	skin	malignant_melanoma	Substitution - Missense
c.1439A>G; p.Q480R; 4:87663217-87663217	pancreas	carcinoid-endocrine_tumour	Substitution - Missense
c.1293G>A; p.E431E; 4:87663071-87663071	kidney	carcinoma; papillary_renal_cell_carcinoma	Substitution - coding silent
c.1359C>T; p.D453D; 4:87663137-87663137	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - coding silent
c.1069G>A; p.E357K; 4:87662847-87662847	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1069G>A; p.E357K; 4:87662847-87662847	skin	malignant_melanoma	Substitution - Missense
c.1230G>A; p.E410E; 4:87663008-87663008	urinary_tract; bladder	carcinoma	Substitution - coding silent
c.721G>T; p.E241*; 4:87662499-87662499	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Nonsense
c.721G>T; p.E241*; 4:87662499-87662499	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Nonsense
c.1230G>A; p.E410E; 4:87663008-87663008	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.960C>A; p.D320E; 4:87662738-87662738	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1230G>A; p.E410E; 4:87663008-87663008	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - coding silent
c.624C>T; p.S208S; 4:87662402-87662402	pancreas	NS	Substitution - coding silent
c.136-3C>T; p.?; 4:87659428-87659428	lung	carcinoma; squamous_cell_carcinoma	Unknown
c.859A>T; p.T287S; 4:87662637-87662637	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1327C>A; p.Q443K; 4:87663105-87663105	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1404C>T; p.S468S; 4:87663182-87663182	upper_aerodigestive_tract; mouth	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.850G>A; p.D284N; 4:87662628-87662628	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1404C>T; p.S468S; 4:87663182-87663182	upper_aerodigestive_tract; mouth	carcinoma	Substitution - coding silent
c.105T>C; p.G35G; 4:87659222-87659222	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.307G>T; p.D103Y; 4:87662085-87662085	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.815G>A; p.R272H; 4:87662593-87662593	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1144G>A; p.D382N; 4:87662922-87662922	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1218C>T; p.S406S; 4:87662996-87662996	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1218C>T; p.S406S; 4:87662996-87662996	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - coding silent
c.631G>A; p.D211N; 4:87662409-87662409	skin; scalp	malignant_melanoma	Substitution - Missense
c.1408G>A; p.E470K; 4:87663186-87663186	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.767G>T; p.G256V; 4:87662545-87662545	soft_tissue; blood_vessel	angiosarcoma	Substitution - Missense
c.1403C>G; p.S468C; 4:87663181-87663181	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.977C>T; p.S326F; 4:87662755-87662755	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.981G>A; p.Q327Q; 4:87662759-87662759	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - coding silent
c.85G>T; p.D29Y; 4:87657062-87657062	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1351G>A; p.E451K; 4:87663129-87663129	skin	malignant_melanoma	Substitution - Missense
c.336C>T; p.D112D; 4:87662114-87662114	ovary	carcinoma; serous_carcinoma	Substitution - coding silent
c.1336G>A; p.E446K; 4:87663114-87663114	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1336G>A; p.E446K; 4:87663114-87663114	skin	malignant_melanoma	Substitution - Missense
c.216A>G; p.S72S; 4:87661994-87661994	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.229G>T; p.G77C; 4:87662007-87662007	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.625G>A; p.E209K; 4:87662403-87662403	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.625G>A; p.E209K; 4:87662403-87662403	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.1134G>A; p.Q378Q; 4:87662912-87662912	skin	malignant_melanoma	Substitution - coding silent
c.1040C>G; p.S347*; 4:87662818-87662818	lung	carcinoma; adenocarcinoma	Substitution - Nonsense
c.41C>T; p.S14F; 4:87656533-87656533	skin	malignant_melanoma	Substitution - Missense
c.20T>A; p.L7H; 4:87656512-87656512	liver	carcinoma	Substitution - Missense
c.20T>A; p.L7H; 4:87656512-87656512	liver	carcinoma	Substitution - Missense
c.1105G>A; p.D369N; 4:87662883-87662883	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.1432G>T; p.D478Y; 4:87663210-87663210	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.54+4A>C; p.?; 4:87656550-87656550	oesophagus	carcinoma; adenocarcinoma	Unknown
c.414G>A; p.E138E; 4:87662192-87662192	skin	malignant_melanoma	Substitution - coding silent
c.1354G>T; p.D452Y; 4:87663132-87663132	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.91G>A; p.E31K; 4:87657068-87657068	liver	carcinoma	Substitution - Missense
c.91G>A; p.E31K; 4:87657068-87657068	liver	carcinoma	Substitution - Missense
c.1367C>T; p.S456F; 4:87663145-87663145	skin	malignant_melanoma	Substitution - Missense
c.174A>G; p.S58S; 4:87659469-87659469	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.240T>C; p.D80D; 4:87662018-87662018	bone	Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	Substitution - coding silent
c.235G>T; p.D79Y; 4:87662013-87662013	pancreas	pancreatic_intraepithelial_neoplasia_(PanIN)	Substitution - Missense
c.368C>T; p.P123L; 4:87662146-87662146	pancreas	carcinoma; ductal_carcinoma	Substitution - Missense
c.1300C>A; p.Q434K; 4:87663078-87663078	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.368C>T; p.P123L; 4:87662146-87662146	pancreas	pancreatic_intraepithelial_neoplasia_(PanIN)	Substitution - Missense
c.618C>T; p.D206D; 4:87662396-87662396	oesophagus	carcinoma; adenocarcinoma	Substitution - coding silent
c.472G>A; p.A158T; 4:87662250-87662250	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.797A>C; p.K266T; 4:87662575-87662575	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.797A>C; p.K266T; 4:87662575-87662575	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.956A>G; p.E319G; 4:87662734-87662734	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1042T>C; p.S348P; 4:87662820-87662820	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.55-3T>G; p.?; 4:87657029-87657029	pancreas	carcinoma; adenocarcinoma	Unknown
c.1504_1505GG>AT; p.G502M; 4:87663282-87663283	lung; right_lower_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.34G>A; p.G12R; 4:87656526-87656526	skin	malignant_melanoma	Substitution - Missense
c.1096G>T; p.D366Y; 4:87662874-87662874	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1335G>A; p.E445E; 4:87663113-87663113	skin	malignant_melanoma	Substitution - coding silent
c.292G>A; p.G98R; 4:87662070-87662070	skin	malignant_melanoma	Substitution - Missense
c.807G>A; p.R269R; 4:87662585-87662585	skin	malignant_melanoma	Substitution - coding silent
c.943G>A; p.G315S; 4:87662721-87662721	skin	malignant_melanoma	Substitution - Missense
c.943G>A; p.G315S; 4:87662721-87662721	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.475C>A; p.Q159K; 4:87662253-87662253	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.873C>T; p.V291V; 4:87662651-87662651	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.1230G>T; p.E410D; 4:87663008-87663008	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.1485C>G; p.A495A; 4:87663263-87663263	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.1299C>T; p.L433L; 4:87663077-87663077	skin	malignant_melanoma	Substitution - coding silent
c.1392A>C; p.E464D; 4:87663170-87663170	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.868G>T; p.E290*; 4:87662646-87662646	breast	carcinoma	Substitution - Nonsense
c.15C>A; p.I5I; 4:87656507-87656507	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.489T>C; p.S163S; 4:87662267-87662267	ovary	other; neoplasm	Substitution - coding silent
c.1015G>A; p.E339K; 4:87662793-87662793	skin	malignant_melanoma	Substitution - Missense
c.1527delC; p.Q510fs*>4; 4:87663305-87663305	breast	carcinoma	Deletion - Frameshift
c.115C>T; p.Q39*; 4:87659232-87659232	breast	carcinoma	Substitution - Nonsense
c.1102C>A; p.P368T; 4:87662880-87662880	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1176C>T; p.L392L; 4:87662954-87662954	skin	malignant_melanoma	Substitution - coding silent
c.973C>A; p.L325M; 4:87662751-87662751	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.641G>A; p.G214E; 4:87662419-87662419	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.932G>A; p.R311K; 4:87662710-87662710	skin	malignant_melanoma	Substitution - Missense
c.1455G>A; p.E485E; 4:87663233-87663233	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - coding silent
c.344G>A; p.G115D; 4:87662122-87662122	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1257G>A; p.P419P; 4:87663035-87663035	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.730G>A; p.E244K; 4:87662508-87662508	kidney	carcinoma; papillary_renal_cell_carcinoma	Substitution - Missense
c.424G>T; p.D142Y; 4:87662202-87662202	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.1417T>C; p.S473P; 4:87663195-87663195	haematopoietic_and_lymphoid_tissue; lymph_node	lymphoid_neoplasm; diffuse_large_B_cell_lymphoma	Substitution - Missense
c.196C>T; p.P66S; 4:87661974-87661974	autonomic_ganglia	neuroblastoma	Substitution - Missense

Annotation category 5

Basic annotation

Literature evidence

Expression

Somatic mutation

Network

ceRNA

Gene information

COSMIC somatic mutation