Cancer metastasis database

Annotation category 5

Gene information

Gene ID 1672
Symbol

DEFB1

Synonymous

BD1|DEFB-1|DEFB101|HBD1

Full name

defensin, beta 1

Gene description

BD-1|beta defensin 1|beta-defensin 1|beta-defensin-1

Cytoband

8p23.1

Gene type

protein-coding

Synonymous

MIM:602056; HGNC:HGNC:2766; Ensembl:ENSG00000164825; HPRD:03634; Vega:OTTHUMG00000090367

COSMIC somatic mutation

Mutation (CDS; AA; Chr)

Site

Histology

Mutation Type

c.8C>A; p.T3N; 8:6877850-6877850

breastcarcinomaSubstitution - Missense

c.99T>A; p.D33E; 8:6870789-6870789

livercarcinomaSubstitution - Missense

c.99T>A; p.D33E; 8:6870789-6870789

livercarcinomaSubstitution - Missense

c.92G>A; p.R31K; 8:6870796-6870796

skinmalignant_melanomaSubstitution - Missense

c.92G>A; p.R31K; 8:6870796-6870796

skinmalignant_melanomaSubstitution - Missense

c.127C>T; p.Q43*; 8:6870761-6870761

stomachcarcinoma; adenocarcinomaSubstitution - Nonsense

c.79G>C; p.G27R; 8:6870809-6870809

upper_aerodigestive_tract; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.124G>T; p.G42W; 8:6870764-6870764

livercarcinomaSubstitution - Missense

c.14A>G; p.Y5C; 8:6877844-6877844

stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.73C>T; p.L25F; 8:6870815-6870815

skinmalignant_melanomaSubstitution - Missense

c.128A>G; p.Q43R; 8:6870760-6870760

lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense