| Gene ID | 1385 |
| Symbol | CREB1 |
| Synonymous | CREB |
| Full name | cAMP responsive element binding protein 1 |
| Gene description | CREB-1|active transcription factor CREB|cAMP-response element-binding protein-1|cAMP-responsive element-binding protein 1|cyclic AMP-responsive element-binding protein 1|transactivator protein |
| Cytoband | 2q34 |
| Gene type | protein-coding |
| Synonymous | MIM:123810; HGNC:HGNC:2345; Ensembl:ENSG00000118260; HPRD:00442; Vega:OTTHUMG00000132936 |
Mutation (CDS; AA; Chr) | Site | Histology | Mutation Type |
|---|---|---|---|
c.711C>T; p.S237S; 2:207575435-207575435 |
central_nervous_system; brain | glioma; astrocytoma_Grade_IV | Substitution - coding silent |
c.850C>T; p.R284*; 2:207577624-207577624 |
haematopoietic_and_lymphoid_tissue | lymphoid_neoplasm; chronic_lymphocytic_leukaemia-small_lymphocytic_lymphoma | Substitution - Nonsense |
c.693G>A; p.Q231Q; 2:207575417-207575417 |
breast | carcinoma; ER-PR-positive_carcinoma | Substitution - coding silent |
c.151C>G; p.P51A; 2:207560262-207560262 |
upper_aerodigestive_tract; pharynx | carcinoma; squamous_cell_carcinoma | Substitution - Missense |
c.325G>A; p.E109K; 2:207567484-207567484 |
NS | NS | Substitution - Missense |