lung cancer gene and literature database Home

Annotation category 5

Basic annotation
Ontology and pathways
Literature evidence
Curated literatures
Expression
Gene expression chart
Somatic mutation
COSMIC and TCGA mutations
Network
Gene interaction
ceRNA
Gene-related ceRNA

Gene information

Gene ID	1244
Symbol	ABCC2
Synonymous	ABC30\|CMOAT\|DJS\|MRP2\|cMRP
Full name	ATP-binding cassette, sub-family C (CFTR/MRP), member 2
Gene description	canalicular multidrug resistance protein\|canalicular multispecific organic anion transporter 1\|multidrug resistance-associated protein 2
Cytoband	10q24
Gene type	protein-coding
Synonymous	MIM:601107; HGNC:HGNC:53; Ensembl:ENSG00000023839; HPRD:03065; Vega:OTTHUMG00000018895

COSMIC somatic mutation

Mutation (CDS; AA; Chr)	Site	Histology	Mutation Type
c.2446C>T; p.L816F; 10:99819095-99819095	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.2079G>T; p.G693G; 10:99813129-99813129	ovary	carcinoma; serous_carcinoma	Substitution - coding silent
c.3119T>C; p.I1040T; 10:99831992-99831992	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.3299G>A; p.R1100H; 10:99834420-99834420	central_nervous_system; brainstem	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.1666C>A; p.L556M; 10:99807519-99807519	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.2732G>A; p.R911Q; 10:99830418-99830418	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.1815G>C; p.Q605H; 10:99808229-99808229	breast	carcinoma	Substitution - Missense
c.778C>T; p.R260W; 10:99797242-99797242	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.778C>T; p.R260W; 10:99797242-99797242	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.778C>T; p.R260W; 10:99797242-99797242	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.778C>T; p.R260W; 10:99797242-99797242	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.997G>T; p.D333Y; 10:99799336-99799336	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.2767C>T; p.H923Y; 10:99830735-99830735	skin	malignant_melanoma	Substitution - Missense
c.1099T>G; p.L367V; 10:99800453-99800453	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.3692A>G; p.D1231G; 10:99842044-99842044	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.1099T>G; p.L367V; 10:99800453-99800453	liver	carcinoma	Substitution - Missense
c.4413A>G; p.T1471T; 10:99850701-99850701	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - coding silent
c.3055_3056CA>AG; p.Q1019R; 10:99831782-99831783	skin	malignant_melanoma	Substitution - Missense
c.1731A>C; p.Q577H; 10:99808145-99808145	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1479G>A; p.K493K; 10:99805396-99805396	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.1462C>G; p.Q488E; 10:99804271-99804271	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.2826C>T; p.D942D; 10:99830794-99830794	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1831G>A; p.E611K; 10:99810149-99810149	skin	malignant_melanoma	Substitution - Missense
c.1831G>A; p.E611K; 10:99810149-99810149	skin	malignant_melanoma	Substitution - Missense
c.2307C>T; p.I769I; 10:99818825-99818825	skin	malignant_melanoma	Substitution - coding silent
c.1669-8C>T; p.?; 10:99808075-99808075	endometrium	carcinoma; serous_carcinoma	Unknown
c.2164G>A; p.G722R; 10:99817377-99817377	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.4600G>A; p.E1534K; 10:99851593-99851593	skin; scalp	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.3716G>A; p.G1239D; 10:99842068-99842068	pancreas	carcinoma; ductal_carcinoma	Substitution - Missense
c.2875A>G; p.T959A; 10:99830843-99830843	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1154G>T; p.C385F; 10:99800508-99800508	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.1154G>T; p.C385F; 10:99800508-99800508	prostate	carcinoma; adenocarcinoma	Substitution - Missense
c.213C>T; p.F71F; 10:99792239-99792239	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - coding silent
c.213C>T; p.F71F; 10:99792239-99792239	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.516C>T; p.Y172Y; 10:99793939-99793939	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.2199A>G; p.V733V; 10:99817412-99817412	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.2563T>A; p.F855I; 10:99819212-99819212	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.288C>T; p.V96V; 10:99792314-99792314	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.4285G>A; p.E1429K; 10:99847099-99847099	breast	carcinoma	Substitution - Missense
c.3926A>G; p.Y1309C; 10:99844404-99844404	liver	carcinoma	Substitution - Missense
c.2281C>A; p.L761I; 10:99818799-99818799	oesophagus	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2955G>A; p.A985A; 10:99831682-99831682	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.4121G>A; p.R1374Q; 10:99845757-99845757	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.983T>C; p.L328P; 10:99799322-99799322	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1733A>C; p.K578T; 10:99808147-99808147	urinary_tract; bladder	carcinoma	Substitution - Missense
c.3399T>G; p.I1133M; 10:99834520-99834520	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1034T>C; p.L345S; 10:99800388-99800388	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1882C>T; p.R628*; 10:99810200-99810200	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Nonsense
c.704C>T; p.T235I; 10:99797168-99797168	skin	malignant_melanoma	Substitution - Missense
c.1882C>T; p.R628*; 10:99810200-99810200	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Nonsense
c.1882C>T; p.R628*; 10:99810200-99810200	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Nonsense
c.1882C>T; p.R628*; 10:99810200-99810200	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Nonsense
c.3040G>A; p.D1014N; 10:99831767-99831767	skin	malignant_melanoma	Substitution - Missense
c.3091G>T; p.G1031*; 10:99831818-99831818	lung	carcinoma; small_cell_carcinoma	Substitution - Nonsense
c.3972C>T; p.I1324I; 10:99844450-99844450	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.3771G>T; p.R1257S; 10:99843828-99843828	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.4545C>T; p.C1515C; 10:99851538-99851538	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.3972C>T; p.I1324I; 10:99844450-99844450	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.4494C>T; p.I1498I; 10:99850782-99850782	upper_aerodigestive_tract; mouth	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.2444G>A; p.R815Q; 10:99819093-99819093	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.2444G>A; p.R815Q; 10:99819093-99819093	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.4545C>T; p.C1515C; 10:99851538-99851538	oesophagus; lower_third	carcinoma; adenocarcinoma	Substitution - coding silent
c.3254C>T; p.A1085V; 10:99832127-99832127	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.3372C>T; p.T1124T; 10:99834493-99834493	oesophagus	carcinoma	Substitution - coding silent
c.2778C>T; p.S926S; 10:99830746-99830746	skin	malignant_melanoma	Substitution - coding silent
c.4175G>A; p.R1392K; 10:99846989-99846989	upper_aerodigestive_tract; mouth	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1071G>A; p.L357L; 10:99800425-99800425	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.2766G>A; p.R922R; 10:99830734-99830734	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.2118G>A; p.Q706Q; 10:99817331-99817331	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.3053C>A; p.S1018Y; 10:99831780-99831780	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.1869C>T; p.D623D; 10:99810187-99810187	kidney	carcinoma; papillary_renal_cell_carcinoma	Substitution - coding silent
c.1756T>A; p.F586I; 10:99808170-99808170	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.3122C>T; p.A1041V; 10:99831995-99831995	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.3122C>T; p.A1041V; 10:99831995-99831995	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.2557G>A; p.G853R; 10:99819206-99819206	skin	malignant_melanoma	Substitution - Missense
c.3247A>T; p.R1083W; 10:99832120-99832120	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.3212T>G; p.F1071C; 10:99832085-99832085	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1579A>C; p.N527H; 10:99807432-99807432	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2366C>G; p.S789C; 10:99818884-99818884	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.4275G>T; p.G1425G; 10:99847089-99847089	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.4356T>C; p.L1452L; 10:99850644-99850644	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.3787G>A; p.E1263K; 10:99843844-99843844	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.3787G>T; p.E1263*; 10:99843844-99843844	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Nonsense
c.2571G>T; p.K857N; 10:99819220-99819220	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.3847C>A; p.P1283T; 10:99844325-99844325	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.632G>A; p.S211N; 10:99794468-99794468	skin	malignant_melanoma	Substitution - Missense
c.806C>T; p.S269F; 10:99797270-99797270	skin; face	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1769G>A; p.R590H; 10:99808183-99808183	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.1769G>A; p.R590H; 10:99808183-99808183	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1270A>G; p.M424V; 10:99804079-99804079	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.2083A>G; p.I695V; 10:99813133-99813133	liver	carcinoma	Substitution - Missense
c.3541C>T; p.R1181*; 10:99836217-99836217	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Nonsense
c.1109C>T; p.A370V; 10:99800463-99800463	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2083A>G; p.I695V; 10:99813133-99813133	liver	carcinoma	Substitution - Missense
c.1283C>A; p.A428D; 10:99804092-99804092	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.2548G>T; p.A850S; 10:99819197-99819197	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.3298C>T; p.R1100C; 10:99834419-99834419	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1634T>C; p.V545A; 10:99807487-99807487	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.2548G>T; p.A850S; 10:99819197-99819197	liver	carcinoma	Substitution - Missense
c.2548G>T; p.A850S; 10:99819197-99819197	liver	carcinoma	Substitution - Missense
c.131delC; p.W46fs*33; 10:99784705-99784705	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.131delC; p.W46fs*33; 10:99784705-99784705	large_intestine; caecum	carcinoma; adenocarcinoma	Deletion - Frameshift
c.15C>A; p.F5L; 10:99782859-99782859	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.131delC; p.W46fs*33; 10:99784705-99784705	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.3706G>A; p.D1236N; 10:99842058-99842058	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1789C>T; p.P597S; 10:99808203-99808203	skin	malignant_melanoma	Substitution - Missense
c.2800C>T; p.R934W; 10:99830768-99830768	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1862A>G; p.D621G; 10:99810180-99810180	liver	carcinoma; hepatocellular_carcinoma	Substitution - Missense
c.3606C>T; p.T1202T; 10:99836282-99836282	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.904_905insA; p.D304fs*30; 10:99799243-99799244	stomach	carcinoma; intestinal_adenocarcinoma	Insertion - Frameshift
c.3757A>C; p.N1253H; 10:99843814-99843814	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.2827G>A; p.E943K; 10:99830795-99830795	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2827G>A; p.E943K; 10:99830795-99830795	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.450G>A; p.L150L; 10:99793667-99793667	NS	NS	Substitution - coding silent
c.1457C>T; p.T486I; 10:99804266-99804266	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.4529G>A; p.G1510E; 10:99851522-99851522	skin	malignant_melanoma	Substitution - Missense
c.1249G>A; p.V417I; 10:99804058-99804058	prostate	adenoma	Substitution - Missense
c.1249G>A; p.V417I; 10:99804058-99804058	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.298C>T; p.R100*; 10:99792324-99792324	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Nonsense
c.3314G>A; p.C1105Y; 10:99834435-99834435	urinary_tract; bladder	carcinoma	Substitution - Missense
c.295G>C; p.V99L; 10:99792321-99792321	lung	carcinoma; small_cell_carcinoma	Substitution - Missense
c.2513C>A; p.T838K; 10:99819162-99819162	kidney	carcinoma; papillary_renal_cell_carcinoma	Substitution - Missense
c.2969C>A; p.S990Y; 10:99831696-99831696	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1590G>C; p.K530N; 10:99807443-99807443	breast	carcinoma	Substitution - Missense
c.2701A>G; p.I901V; 10:99830387-99830387	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.2624A>G; p.H875R; 10:99830310-99830310	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2152A>C; p.N718H; 10:99817365-99817365	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.1433C>T; p.A478V; 10:99804242-99804242	prostate	carcinoma	Substitution - Missense
c.1433C>T; p.A478V; 10:99804242-99804242	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1294A>G; p.M432V; 10:99804103-99804103	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1433C>T; p.A478V; 10:99804242-99804242	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.171G>A; p.K57K; 10:99784745-99784745	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.412C>A; p.L138I; 10:99793629-99793629	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1281T>G; p.D427E; 10:99804090-99804090	skin	malignant_melanoma	Substitution - Missense
c.4156C>A; p.L1386M; 10:99846970-99846970	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.608G>A; p.S203N; 10:99794444-99794444	lung	carcinoma; small_cell_carcinoma	Substitution - Missense
c.412C>A; p.L138I; 10:99793629-99793629	breast	carcinoma	Substitution - Missense
c.412C>A; p.L138I; 10:99793629-99793629	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.171G>A; p.K57K; 10:99784745-99784745	skin	malignant_melanoma	Substitution - coding silent
c.412C>A; p.L138I; 10:99793629-99793629	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.882G>C; p.K294N; 10:99799221-99799221	breast	carcinoma; HER-positive_carcinoma	Substitution - Missense
c.1091C>T; p.A364V; 10:99800445-99800445	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.2473C>A; p.L825I; 10:99819122-99819122	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1091C>T; p.A364V; 10:99800445-99800445	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1091C>T; p.A364V; 10:99800445-99800445	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2448C>A; p.L816L; 10:99819097-99819097	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.2689G>T; p.D897Y; 10:99830375-99830375	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; acute_lymphoblastic_B_cell_leukaemia	Substitution - Missense
c.2933C>T; p.S978L; 10:99831660-99831660	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2933C>T; p.S978L; 10:99831660-99831660	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.2216T>C; p.L739P; 10:99817429-99817429	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.3645G>A; p.G1215G; 10:99841997-99841997	skin	malignant_melanoma	Substitution - coding silent
c.1668+7A>T; p.?; 10:99807528-99807528	liver	carcinoma	Unknown
c.3407C>T; p.S1136F; 10:99834528-99834528	oesophagus; lower_third	carcinoma; adenocarcinoma	Substitution - Missense
c.1132C>A; p.L378I; 10:99800486-99800486	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1668+7A>T; p.?; 10:99807528-99807528	liver	carcinoma	Unknown
c.1132C>A; p.L378I; 10:99800486-99800486	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.4585T>C; p.Y1529H; 10:99851578-99851578	breast	carcinoma	Substitution - Missense
c.3448C>T; p.R1150C; 10:99836124-99836124	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2727T>G; p.F909L; 10:99830413-99830413	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.2367T>C; p.S789S; 10:99818885-99818885	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.2367T>C; p.S789S; 10:99818885-99818885	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.3477C>A; p.I1159I; 10:99836153-99836153	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - coding silent
c.1768C>T; p.R590C; 10:99808182-99808182	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; acute_lymphoblastic_leukaemia	Substitution - Missense
c.2775G>A; p.K925K; 10:99830743-99830743	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.285A>G; p.T95T; 10:99792311-99792311	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - coding silent
c.57G>A; p.P19P; 10:99784631-99784631	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.3791C>T; p.T1264I; 10:99843848-99843848	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1032-1G>T; p.?; 10:99800385-99800385	lung	carcinoma; squamous_cell_carcinoma	Unknown
c.1179G>A; p.R393R; 10:99800533-99800533	upper_aerodigestive_tract; mouth	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.3216_3217insT; p.D1073fs*1; 10:99832089-99832090	prostate	carcinoma	Insertion - Frameshift
c.1179G>A; p.R393R; 10:99800533-99800533	upper_aerodigestive_tract; mouth	carcinoma	Substitution - coding silent
c.2500C>A; p.L834M; 10:99819149-99819149	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.3728C>T; p.S1243F; 10:99842080-99842080	liver	carcinoma	Substitution - Missense
c.3568A>T; p.I1190F; 10:99836244-99836244	thyroid	carcinoma	Substitution - Missense
c.3619C>A; p.L1207I; 10:99841971-99841971	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.3728C>T; p.S1243F; 10:99842080-99842080	liver	carcinoma; hepatocellular_carcinoma	Substitution - Missense
c.984G>A; p.L328L; 10:99799323-99799323	kidney	carcinoma; papillary_renal_cell_carcinoma	Substitution - coding silent
c.293C>T; p.A98V; 10:99792319-99792319	autonomic_ganglia	neuroblastoma	Substitution - Missense
c.3121G>T; p.A1041S; 10:99831994-99831994	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.532A>G; p.I178V; 10:99793955-99793955	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.3258C>T; p.G1086G; 10:99832131-99832131	bone; femur	Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	Substitution - coding silent
c.1158C>T; p.F386F; 10:99800512-99800512	biliary_tract; gallbladder	carcinoma; adenocarcinoma	Substitution - coding silent
c.2883+1G>A; p.?; 10:99830852-99830852	stomach	carcinoma; adenocarcinoma	Unknown
c.2731C>T; p.R911*; 10:99830417-99830417	skin	malignant_melanoma	Substitution - Nonsense
c.4045A>G; p.R1349G; 10:99845681-99845681	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.2731C>T; p.R911*; 10:99830417-99830417	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Nonsense
c.412C>T; p.L138F; 10:99793629-99793629	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.2729G>A; p.R910H; 10:99830415-99830415	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.2706C>A; p.T902T; 10:99830392-99830392	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.945C>T; p.F315F; 10:99799284-99799284	breast	carcinoma	Substitution - coding silent
c.2647G>A; p.D883N; 10:99830333-99830333	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.898G>A; p.G300R; 10:99799237-99799237	thyroid	carcinoma	Substitution - Missense
c.732G>A; p.T244T; 10:99797196-99797196	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.898G>A; p.G300R; 10:99799237-99799237	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	Substitution - Missense
c.4210_4212delGAG; p.E1405delE; 10:99847024-99847026	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Deletion - In frame
c.1328C>T; p.S443L; 10:99804137-99804137	oesophagus; middle_third	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2113C>T; p.P705S; 10:99817326-99817326	liver	carcinoma; hepatocellular_carcinoma	Substitution - Missense
c.1602G>T; p.K534N; 10:99807455-99807455	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.4437C>G; p.I1479M; 10:99850725-99850725	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.2365T>C; p.S789P; 10:99818883-99818883	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.2365T>C; p.S789P; 10:99818883-99818883	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.4437C>G; p.I1479M; 10:99850725-99850725	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1949C>T; p.S650L; 10:99811584-99811584	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1949C>T; p.S650L; 10:99811584-99811584	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1908C>A; p.A636A; 10:99811543-99811543	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.940C>T; p.L314L; 10:99799279-99799279	liver	carcinoma	Substitution - coding silent
c.2923G>T; p.G975*; 10:99831650-99831650	oesophagus; middle_third	carcinoma; squamous_cell_carcinoma	Substitution - Nonsense
c.3236G>T; p.R1079L; 10:99832109-99832109	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.431C>A; p.T144N; 10:99793648-99793648	liver	carcinoma	Substitution - Missense
c.431C>A; p.T144N; 10:99793648-99793648	liver	carcinoma	Substitution - Missense
c.3812G>A; p.R1271Q; 10:99843869-99843869	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.460_461delCT; p.L155fs*3; 10:99793677-99793678	lung	carcinoma; adenocarcinoma	Deletion - Frameshift
c.4230G>A; p.L1410L; 10:99847044-99847044	skin	malignant_melanoma	Substitution - coding silent
c.1752C>T; p.T584T; 10:99808166-99808166	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - coding silent
c.497G>A; p.C166Y; 10:99793920-99793920	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.4075A>G; p.I1359V; 10:99845711-99845711	liver	carcinoma	Substitution - Missense
c.2620+1G>A; p.?; 10:99819270-99819270	endometrium	carcinoma; endometrioid_carcinoma	Unknown
c.3148G>A; p.V1050I; 10:99832021-99832021	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.3738C>G; p.L1246L; 10:99842090-99842090	breast	carcinoma	Substitution - coding silent
c.3545T>G; p.F1182C; 10:99836221-99836221	liver	carcinoma; hepatocellular_carcinoma	Substitution - Missense
c.1155C>T; p.C385C; 10:99800509-99800509	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.4186G>A; p.D1396N; 10:99847000-99847000	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2551A>T; p.K851*; 10:99819200-99819200	NS	NS	Substitution - Nonsense
c.912T>A; p.D304E; 10:99799251-99799251	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.3562G>A; p.V1188M; 10:99836238-99836238	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.4273G>T; p.G1425W; 10:99847087-99847087	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.2148G>T; p.K716N; 10:99817361-99817361	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.3628C>T; p.R1210C; 10:99841980-99841980	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.3361C>A; p.P1121T; 10:99834482-99834482	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1405G>T; p.V469L; 10:99804214-99804214	bone	Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	Substitution - Missense
c.1668+9C>T; p.?; 10:99807530-99807530	liver	carcinoma	Unknown
c.1668+9C>T; p.?; 10:99807530-99807530	liver	carcinoma	Unknown
c.2889G>A; p.K963K; 10:99831616-99831616	bone; femur	Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	Substitution - coding silent
c.3027C>A; p.I1009I; 10:99831754-99831754	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - coding silent
c.3027C>A; p.I1009I; 10:99831754-99831754	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.2503G>T; p.G835W; 10:99819152-99819152	kidney	carcinoma; renal_cell_carcinoma	Substitution - Missense
c.1032-10T>C; p.?; 10:99800376-99800376	ovary	other; neoplasm	Unknown
c.3294C>A; p.S1098S; 10:99834415-99834415	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.3294C>A; p.S1098S; 10:99834415-99834415	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.789G>T; p.K263N; 10:99797253-99797253	liver	carcinoma; hepatocellular_carcinoma	Substitution - Missense
c.2008A>G; p.I670V; 10:99813058-99813058	breast	carcinoma	Substitution - Missense
c.3192C>T; p.I1064I; 10:99832065-99832065	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.3436C>T; p.R1146C; 10:99836112-99836112	breast	carcinoma	Substitution - Missense
c.1362C>T; p.F454F; 10:99804171-99804171	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.2821G>A; p.E941K; 10:99830789-99830789	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.632+1G>T; p.?; 10:99794469-99794469	biliary_tract; bile_duct	carcinoma; adenocarcinoma	Unknown
c.908A>T; p.K303I; 10:99799247-99799247	pancreas	carcinoma	Substitution - Missense
c.1883G>A; p.R628Q; 10:99810201-99810201	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.681G>A; p.W227*; 10:99797145-99797145	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Nonsense
c.3039C>T; p.T1013T; 10:99831766-99831766	breast	carcinoma	Substitution - coding silent
c.196C>A; p.L66I; 10:99784770-99784770	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.1745C>T; p.S582F; 10:99808159-99808159	skin	malignant_melanoma	Substitution - Missense
c.4198A>T; p.N1400Y; 10:99847012-99847012	ovary	carcinoma	Substitution - Missense
c.2934G>A; p.S978S; 10:99831661-99831661	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1950G>A; p.S650S; 10:99811585-99811585	oesophagus	carcinoma; adenocarcinoma	Substitution - coding silent
c.2685C>T; p.P895P; 10:99830371-99830371	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.1840G>A; p.E614K; 10:99810158-99810158	breast	carcinoma	Substitution - Missense
c.1950G>A; p.S650S; 10:99811585-99811585	liver	carcinoma	Substitution - coding silent
c.1950G>A; p.S650S; 10:99811585-99811585	liver	carcinoma	Substitution - coding silent
c.2551delA; p.G853fs*7; 10:99819200-99819200	large_intestine; caecum	carcinoma; adenocarcinoma	Deletion - Frameshift
c.4349C>T; p.A1450V; 10:99850637-99850637	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.3147C>T; p.F1049F; 10:99832020-99832020	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.2856T>A; p.I952I; 10:99830824-99830824	skin	malignant_melanoma	Substitution - coding silent
c.2954C>T; p.A985V; 10:99831681-99831681	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.191T>A; p.L64H; 10:99784765-99784765	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.145C>T; p.L49F; 10:99784719-99784719	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.2077G>A; p.G693R; 10:99813127-99813127	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1041C>A; p.I347I; 10:99800395-99800395	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.2728C>T; p.R910C; 10:99830414-99830414	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2127G>A; p.W709*; 10:99817340-99817340	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Nonsense
c.779G>A; p.R260Q; 10:99797243-99797243	breast	carcinoma	Substitution - Missense
c.1002C>A; p.I334I; 10:99799341-99799341	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.455G>A; p.R152Q; 10:99793672-99793672	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.455G>A; p.R152Q; 10:99793672-99793672	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1959A>T; p.T653T; 10:99811594-99811594	urinary_tract; bladder	carcinoma	Substitution - coding silent
c.455G>A; p.R152Q; 10:99793672-99793672	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.2064delG; p.E689fs*27; 10:99813114-99813114	lung	carcinoma; adenocarcinoma	Deletion - Frameshift
c.2368G>T; p.A790S; 10:99818886-99818886	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.913G>C; p.V305L; 10:99799252-99799252	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.1342A>C; p.I448L; 10:99804151-99804151	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.2322T>A; p.A774A; 10:99818840-99818840	kidney	other; neoplasm	Substitution - coding silent
c.2686G>A; p.E896K; 10:99830372-99830372	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.4473C>T; p.I1491I; 10:99850761-99850761	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.3767T>G; p.V1256G; 10:99843824-99843824	thyroid	other; neoplasm	Substitution - Missense
c.572C>A; p.S191*; 10:99793995-99793995	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Nonsense
c.4085G>C; p.G1362A; 10:99845721-99845721	pancreas	carcinoma; ductal_carcinoma	Substitution - Missense
c.164G>T; p.R55M; 10:99784738-99784738	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense

Annotation category 5

Basic annotation

Literature evidence

Expression

Somatic mutation

Network

ceRNA

Gene information

COSMIC somatic mutation