lung cancer gene and literature database Home

Annotation category 5

Basic annotation
Ontology and pathways
Literature evidence
Curated literatures
Expression
Gene expression chart
Somatic mutation
COSMIC and TCGA mutations
Network
Gene interaction
ceRNA
Gene-related ceRNA

Gene information

Gene ID	116154
Symbol	PHACTR3
Synonymous	C20orf101\|H17739\|PPP1R123\|SCAPIN1\|SCAPININ
Full name	phosphatase and actin regulator 3
Gene description	protein phosphatase 1, regulatory subunit 123\|scaffold-associated PP1-inhibiting protein
Cytoband	20q13.32-q13.33
Gene type	protein-coding
Synonymous	MIM:608725; HGNC:HGNC:15833; Ensembl:ENSG00000087495; HPRD:10571; Vega:OTTHUMG00000032869

COSMIC somatic mutation

Mutation (CDS; AA; Chr)	Site	Histology	Mutation Type
c.1516G>A; p.E506K; 20:59841464-59841464	skin	malignant_melanoma	Substitution - Missense
c.1370G>T; p.R457I; 20:59836546-59836546	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1384+1G>A; p.?; 20:59836561-59836561	stomach	carcinoma; adenocarcinoma	Unknown
c.502G>A; p.D168N; 20:59755325-59755325	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.1377C>A; p.I459I; 20:59836553-59836553	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - coding silent
c.135G>C; p.T45T; 20:59743123-59743123	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - coding silent
c.1603G>T; p.E535*; 20:59845204-59845204	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Nonsense
c.1603G>T; p.E535*; 20:59845204-59845204	large_intestine	carcinoma; adenocarcinoma	Substitution - Nonsense
c.1616A>G; p.Y539C; 20:59845217-59845217	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1356A>C; p.E452D; 20:59836532-59836532	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.504C>A; p.D168E; 20:59755327-59755327	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.504C>A; p.D168E; 20:59755327-59755327	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.504C>A; p.D168E; 20:59755327-59755327	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.504C>A; p.D168E; 20:59755327-59755327	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.504C>A; p.D168E; 20:59755327-59755327	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.504C>A; p.D168E; 20:59755327-59755327	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.895A>G; p.R299G; 20:59773422-59773422	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1618A>C; p.K540Q; 20:59845219-59845219	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.990G>A; p.T330T; 20:59774306-59774306	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.311G>A; p.G104D; 20:59747788-59747788	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.250delA; p.N85fs*4; 20:59743238-59743238	large_intestine	carcinoma; adenocarcinoma	Deletion - Frameshift
c.1409A>C; p.E470A; 20:59840393-59840393	stomach	carcinoma; intestinal_adenocarcinoma	Substitution - Missense
c.283C>T; p.L95L; 20:59747760-59747760	skin	malignant_melanoma	Substitution - coding silent
c.1038C>T; p.D346D; 20:59774354-59774354	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.398G>A; p.R133Q; 20:59755221-59755221	oesophagus; lower_third	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.243G>A; p.R81R; 20:59743231-59743231	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.398G>A; p.R133Q; 20:59755221-59755221	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1038C>T; p.D346D; 20:59774354-59774354	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1420G>A; p.E474K; 20:59840404-59840404	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.184G>T; p.V62L; 20:59743172-59743172	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1545G>A; p.R515R; 20:59841493-59841493	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.462C>T; p.P154P; 20:59755285-59755285	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.1513G>A; p.V505M; 20:59841461-59841461	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; acute_lymphoblastic_T_cell_leukaemia	Substitution - Missense
c.1138C>A; p.Q380K; 20:59774454-59774454	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.301G>A; p.G101S; 20:59747778-59747778	breast	carcinoma	Substitution - Missense
c.317A>G; p.E106G; 20:59747794-59747794	skin	malignant_melanoma	Substitution - Missense
c.711G>A; p.P237P; 20:59767355-59767355	breast	carcinoma	Substitution - coding silent
c.1139A>T; p.Q380L; 20:59774455-59774455	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.860C>A; p.P287H; 20:59773387-59773387	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.894C>G; p.H298Q; 20:59773421-59773421	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1328A>C; p.K443T; 20:59806194-59806194	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.219G>T; p.R73S; 20:59743207-59743207	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.219G>T; p.R73S; 20:59743207-59743207	lung	carcinoma; small_cell_carcinoma	Substitution - Missense
c.1091A>G; p.E364G; 20:59774407-59774407	bone	Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	Substitution - Missense
c.721G>A; p.A241T; 20:59767365-59767365	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.1622G>T; p.S541I; 20:59845223-59845223	ovary	other; neoplasm	Substitution - Missense
c.148C>A; p.P50T; 20:59743136-59743136	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.934G>A; p.G312R; 20:59774250-59774250	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.862C>A; p.L288I; 20:59773389-59773389	lung; right_lower_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.404T>C; p.V135A; 20:59755227-59755227	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1492C>T; p.L498L; 20:59841440-59841440	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.441G>A; p.L147L; 20:59755264-59755264	oesophagus; lower_third	carcinoma; adenocarcinoma	Substitution - coding silent
c.141G>T; p.P47P; 20:59743129-59743129	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.144G>A; p.A48A; 20:59743132-59743132	pancreas	carcinoma	Substitution - coding silent
c.1614G>A; p.E538E; 20:59845215-59845215	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.739A>T; p.K247*; 20:59767383-59767383	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Nonsense
c.135G>A; p.T45T; 20:59743123-59743123	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.178C>T; p.P60S; 20:59743166-59743166	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.684_685CC>AA; p.P229T; 20:59767328-59767329	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.824C>T; p.P275L; 20:59773351-59773351	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1090G>T; p.E364*; 20:59774406-59774406	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Nonsense
c.437C>T; p.T146M; 20:59755260-59755260	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.437C>T; p.T146M; 20:59755260-59755260	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.134C>T; p.T45M; 20:59743122-59743122	oesophagus; lower_third	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.745G>T; p.V249F; 20:59767389-59767389	lung	carcinoma; small_cell_carcinoma	Substitution - Missense
c.1187G>A; p.R396Q; 20:59806053-59806053	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.384C>T; p.P128P; 20:59755207-59755207	pancreas	NS	Substitution - coding silent
c.1311C>T; p.I437I; 20:59806177-59806177	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.119-1G>A; p.?; 20:59743106-59743106	lung	carcinoma; adenocarcinoma	Unknown
c.710C>T; p.P237L; 20:59767354-59767354	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1071G>T; p.K357N; 20:59774387-59774387	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.485C>T; p.T162M; 20:59755308-59755308	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.816C>G; p.L272L; 20:59773343-59773343	upper_aerodigestive_tract; mouth	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.197G>T; p.S66I; 20:59743185-59743185	lung	carcinoma; small_cell_carcinoma	Substitution - Missense
c.1243G>A; p.E415K; 20:59806109-59806109	skin	malignant_melanoma	Substitution - Missense
c.996C>T; p.S332S; 20:59774312-59774312	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.364G>A; p.E122K; 20:59755187-59755187	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.984G>A; p.S328S; 20:59774300-59774300	pancreas	carcinoma; ductal_carcinoma	Substitution - coding silent
c.1493T>G; p.L498R; 20:59841441-59841441	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.579C>T; p.D193D; 20:59767223-59767223	pancreas	carcinoma	Substitution - coding silent
c.1109C>T; p.S370F; 20:59774425-59774425	skin	malignant_melanoma	Substitution - Missense
c.286G>C; p.E96Q; 20:59747763-59747763	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1443A>C; p.R481S; 20:59840427-59840427	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1299C>A; p.I433I; 20:59806165-59806165	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.281C>T; p.A94V; 20:59747758-59747758	urinary_tract; bladder	carcinoma	Substitution - Missense
c.216C>A; p.G72G; 20:59743204-59743204	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1143C>T; p.D381D; 20:59774459-59774459	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.275C>T; p.T92M; 20:59743263-59743263	ovary	other; neoplasm	Substitution - Missense
c.607G>T; p.E203*; 20:59767251-59767251	kidney	other; neoplasm	Substitution - Nonsense
c.143C>T; p.A48V; 20:59743131-59743131	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.298G>C; p.A100P; 20:59747775-59747775	breast	carcinoma	Substitution - Missense
c.806G>T; p.R269L; 20:59773333-59773333	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.765C>G; p.L255L; 20:59773292-59773292	breast	carcinoma	Substitution - coding silent
c.542-7G>A; p.?; 20:59767179-59767179	pancreas	carcinoma	Unknown
c.145C>A; p.R49S; 20:59743133-59743133	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.172C>T; p.R58*; 20:59743160-59743160	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Nonsense
c.1529C>T; p.A510V; 20:59841477-59841477	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1439C>T; p.T480I; 20:59840423-59840423	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1158C>T; p.N386N; 20:59774474-59774474	oesophagus	carcinoma; adenocarcinoma	Substitution - coding silent
c.1678T>C; p.*560Q; 20:59847128-59847128	liver	carcinoma	Nonstop extension
c.1338C>T; p.S446S; 20:59836514-59836514	liver	carcinoma	Substitution - coding silent
c.1338C>T; p.S446S; 20:59836514-59836514	liver	carcinoma	Substitution - coding silent
c.303C>A; p.G101G; 20:59747780-59747780	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.993C>T; p.S331S; 20:59774309-59774309	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.242G>A; p.R81K; 20:59743230-59743230	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1554C>A; p.D518E; 20:59841502-59841502	upper_aerodigestive_tract; larynx	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1301G>C; p.R434P; 20:59806167-59806167	breast	carcinoma	Substitution - Missense
c.950G>A; p.G317E; 20:59774266-59774266	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.146G>A; p.R49H; 20:59743134-59743134	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.146G>A; p.R49H; 20:59743134-59743134	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.146G>A; p.R49H; 20:59743134-59743134	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.998T>G; p.V333G; 20:59774314-59774314	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.571G>A; p.E191K; 20:59767215-59767215	skin	malignant_melanoma	Substitution - Missense
c.792C>T; p.A264A; 20:59773319-59773319	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1224G>A; p.R408R; 20:59806090-59806090	skin	malignant_melanoma	Substitution - coding silent
c.675G>T; p.V225V; 20:59767319-59767319	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.389G>A; p.G130E; 20:59755212-59755212	skin	malignant_melanoma	Substitution - Missense
c.173G>A; p.R58Q; 20:59743161-59743161	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.173G>A; p.R58Q; 20:59743161-59743161	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.173G>A; p.R58Q; 20:59743161-59743161	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.420C>T; p.P140P; 20:59755243-59755243	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.313C>T; p.R105*; 20:59747790-59747790	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Nonsense
c.1417A>C; p.R473R; 20:59840401-59840401	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.1186C>T; p.R396W; 20:59806052-59806052	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.1186C>T; p.R396W; 20:59806052-59806052	central_nervous_system; brain	glioma	Substitution - Missense
c.639C>T; p.S213S; 20:59767283-59767283	ovary	other; neoplasm	Substitution - coding silent
c.280+1G>A; p.?; 20:59743269-59743269	ovary	carcinoma; serous_carcinoma	Unknown
c.1212C>T; p.A404A; 20:59806078-59806078	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.1212C>T; p.A404A; 20:59806078-59806078	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - coding silent
c.671C>T; p.S224F; 20:59767315-59767315	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1498C>T; p.R500*; 20:59841446-59841446	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Nonsense
c.1498C>T; p.R500*; 20:59841446-59841446	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Nonsense
c.1498C>T; p.R500*; 20:59841446-59841446	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Nonsense
c.858G>T; p.R286R; 20:59773385-59773385	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.475G>A; p.A159T; 20:59755298-59755298	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1253A>G; p.D418G; 20:59806119-59806119	urinary_tract; bladder	carcinoma; transitional_cell_carcinoma	Substitution - Missense
c.126_127GG>AA; p.M42_D43>IN; 20:59743114-59743115	skin; head_neck	carcinoma; squamous_cell_carcinoma	Complex - compound substitution
c.1253A>G; p.D418G; 20:59806119-59806119	urinary_tract; bladder	carcinoma	Substitution - Missense
c.139C>T; p.P47S; 20:59743127-59743127	urinary_tract; bladder	carcinoma	Substitution - Missense
c.1494G>A; p.L498L; 20:59841442-59841442	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - coding silent
c.139C>T; p.P47S; 20:59743127-59743127	urinary_tract; bladder	carcinoma; transitional_cell_carcinoma	Substitution - Missense
c.1065C>T; p.A355A; 20:59774381-59774381	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.1065C>T; p.A355A; 20:59774381-59774381	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.976C>T; p.R326C; 20:59774292-59774292	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.1642G>T; p.A548S; 20:59845243-59845243	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.690C>T; p.S230S; 20:59767334-59767334	skin	malignant_melanoma	Substitution - coding silent
c.329A>G; p.K110R; 20:59747806-59747806	oesophagus; lower_third	carcinoma; adenocarcinoma	Substitution - Missense
c.612C>A; p.L204L; 20:59767256-59767256	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.989C>T; p.T330M; 20:59774305-59774305	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.748A>G; p.T250A; 20:59767392-59767392	pancreas	carcinoma	Substitution - Missense
c.748A>G; p.T250A; 20:59767392-59767392	pancreas	carcinoma; ductal_carcinoma	Substitution - Missense
c.1003C>T; p.R335W; 20:59774319-59774319	liver	carcinoma; hepatocellular_carcinoma	Substitution - Missense
c.1003C>T; p.R335W; 20:59774319-59774319	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1003C>T; p.R335W; 20:59774319-59774319	liver	carcinoma; hepatocellular_carcinoma	Substitution - Missense
c.248A>G; p.K83R; 20:59743236-59743236	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.1089G>A; p.K363K; 20:59774405-59774405	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.595C>T; p.P199S; 20:59767239-59767239	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1011G>A; p.K337K; 20:59774327-59774327	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.737_738insA; p.N248fs*48; 20:59767381-59767382	large_intestine; colon	carcinoma; adenocarcinoma	Insertion - Frameshift
c.793G>A; p.D265N; 20:59773320-59773320	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1072G>C; p.E358Q; 20:59774388-59774388	breast	carcinoma	Substitution - Missense
c.1566G>A; p.T522T; 20:59841514-59841514	skin	malignant_melanoma	Substitution - coding silent
c.638C>T; p.S213F; 20:59767282-59767282	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.638C>T; p.S213F; 20:59767282-59767282	skin; hand	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1566G>A; p.T522T; 20:59841514-59841514	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1144G>A; p.E382K; 20:59774460-59774460	skin	malignant_melanoma	Substitution - Missense
c.638C>T; p.S213F; 20:59767282-59767282	skin	malignant_melanoma	Substitution - Missense
c.1144G>A; p.E382K; 20:59774460-59774460	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; NK-T_cell_lymphoma	Substitution - Missense
c.697C>A; p.L233M; 20:59767341-59767341	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.951G>A; p.G317G; 20:59774267-59774267	central_nervous_system; brain	glioma	Substitution - coding silent
c.342G>A; p.L114L; 20:59747819-59747819	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - coding silent
c.253A>G; p.N85D; 20:59743241-59743241	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.639C>A; p.S213S; 20:59767283-59767283	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.254delA; p.N85fs*4; 20:59743242-59743242	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.256G>A; p.E86K; 20:59743244-59743244	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.906C>T; p.A302A; 20:59773433-59773433	liver	carcinoma	Substitution - coding silent
c.906C>T; p.A302A; 20:59773433-59773433	liver	carcinoma	Substitution - coding silent
c.802C>T; p.L268F; 20:59773329-59773329	lung	carcinoma; small_cell_carcinoma	Substitution - Missense
c.1399A>C; p.T467P; 20:59840383-59840383	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.692C>T; p.P231L; 20:59767336-59767336	skin	malignant_melanoma	Substitution - Missense
c.140C>T; p.P47L; 20:59743128-59743128	oesophagus	carcinoma	Substitution - Missense
c.318G>A; p.E106E; 20:59747795-59747795	skin	malignant_melanoma	Substitution - coding silent
c.833C>A; p.S278Y; 20:59773360-59773360	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.916C>T; p.R306C; 20:59773443-59773443	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.740A>G; p.K247R; 20:59767384-59767384	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; diffuse_large_B_cell_lymphoma	Substitution - Missense
c.964C>T; p.R322W; 20:59774280-59774280	pancreas	carcinoma	Substitution - Missense
c.464G>A; p.G155E; 20:59755287-59755287	skin	malignant_melanoma	Substitution - Missense
c.345G>C; p.E115D; 20:59747822-59747822	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.119-5T>G; p.?; 20:59743102-59743102	prostate	carcinoma	Unknown
c.362C>T; p.A121V; 20:59755185-59755185	urinary_tract; bladder	carcinoma	Substitution - Missense

Annotation category 5

Basic annotation

Literature evidence

Expression

Somatic mutation

Network

ceRNA

Gene information

COSMIC somatic mutation