lung cancer gene and literature database Home

Annotation category 5

Basic annotation
Ontology and pathways
Literature evidence
Curated literatures
Expression
Gene expression chart
Somatic mutation
COSMIC and TCGA mutations
Network
Gene interaction
ceRNA
Gene-related ceRNA

Gene information

Gene ID	11167
Symbol	FSTL1
Synonymous	FRP\|FSL1\|MIR198
Full name	follistatin-like 1
Gene description	follistatin-like protein 1\|follistatin-related protein 1
Cytoband	3q13.33
Gene type	protein-coding
Synonymous	MIM:605547; HGNC:HGNC:3972; HPRD:16120

COSMIC somatic mutation

Mutation (CDS; AA; Chr)	Site	Histology	Mutation Type
c.261A>G; p.G87G; 3:120411891-120411891	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.261A>G; p.G87G; 3:120411891-120411891	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.343C>T; p.Q115*; 3:120409651-120409651	urinary_tract; bladder	carcinoma	Substitution - Nonsense
c.102G>T; p.V34V; 3:120415989-120415989	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - coding silent
c.379C>A; p.Q127K; 3:120409615-120409615	skin	malignant_melanoma	Substitution - Missense
c.273_274GG>AA; p.V92I; 3:120411878-120411879	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.329C>A; p.P110Q; 3:120410954-120410954	adrenal_gland; adrenal_gland	adrenal_cortical_carcinoma; functioning	Substitution - Missense
c.716C>T; p.T239M; 3:120402897-120402897	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.716C>T; p.T239M; 3:120402897-120402897	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.241C>T; p.R81*; 3:120411911-120411911	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Nonsense
c.549G>T; p.T183T; 3:120404885-120404885	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.260G>T; p.G87V; 3:120411892-120411892	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.300G>A; p.E100E; 3:120410983-120410983	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.526G>A; p.E176K; 3:120404908-120404908	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.624T>C; p.N208N; 3:120403312-120403312	kidney	carcinoma; papillary_renal_cell_carcinoma	Substitution - coding silent
c.678C>A; p.F226L; 3:120403258-120403258	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.768C>T; p.A256A; 3:120402845-120402845	skin	malignant_melanoma	Substitution - coding silent
c.310G>A; p.V104I; 3:120410973-120410973	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.195G>T; p.V65V; 3:120411957-120411957	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.256_257delAC; p.T86fs*7; 3:120411895-120411896	liver	carcinoma; hepatocellular_carcinoma	Deletion - Frameshift
c.883-1G>T; p.?; 3:120396997-120396997	endometrium	carcinoma; endometrioid_carcinoma	Unknown
c.582G>A; p.R194R; 3:120403354-120403354	skin	malignant_melanoma	Substitution - coding silent
c.718T>C; p.Y240H; 3:120402895-120402895	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.25G>A; p.A9T; 3:120450722-120450722	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.861C>A; p.V287V; 3:120399904-120399904	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.501A>G; p.E167E; 3:120404933-120404933	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.674C>A; p.S225Y; 3:120403262-120403262	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.646C>T; p.Q216*; 3:120403290-120403290	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Nonsense
c.897G>T; p.K299N; 3:120396982-120396982	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.74G>A; p.R25K; 3:120416017-120416017	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.556G>T; p.D186Y; 3:120404878-120404878	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.708G>A; p.E236E; 3:120402905-120402905	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.605T>A; p.I202N; 3:120403331-120403331	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.235C>T; p.L79L; 3:120411917-120411917	prostate	carcinoma; adenocarcinoma	Substitution - coding silent
c.368G>A; p.R123H; 3:120409626-120409626	large_intestine; rectum	NS	Substitution - Missense
c.694+1G>A; p.?; 3:120403241-120403241	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Unknown
c.694+1G>A; p.?; 3:120403241-120403241	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Unknown
c.361C>T; p.L121F; 3:120409633-120409633	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.682C>T; p.P228S; 3:120403254-120403254	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.298G>T; p.E100*; 3:120411854-120411854	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Nonsense
c.759T>C; p.C253C; 3:120402854-120402854	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.739G>T; p.E247*; 3:120402874-120402874	lung	carcinoma; squamous_cell_carcinoma	Substitution - Nonsense
c.113C>T; p.A38V; 3:120415978-120415978	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.697T>A; p.C233S; 3:120402916-120402916	stomach	adenocarcinoma	Substitution - Missense
c.522G>T; p.Q174H; 3:120404912-120404912	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.364C>T; p.R122*; 3:120409630-120409630	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Nonsense
c.371G>A; p.R124H; 3:120409623-120409623	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.549G>A; p.T183T; 3:120404885-120404885	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - coding silent
c.549G>A; p.T183T; 3:120404885-120404885	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - coding silent
c.558C>A; p.D186E; 3:120404876-120404876	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.251G>A; p.C84Y; 3:120411901-120411901	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.549G>A; p.T183T; 3:120404885-120404885	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - coding silent
c.51G>T; p.W17C; 3:120450696-120450696	lung	carcinoma; small_cell_carcinoma	Substitution - Missense
c.324C>T; p.A108A; 3:120410959-120410959	liver	carcinoma	Substitution - coding silent
c.324C>T; p.A108A; 3:120410959-120410959	liver	carcinoma	Substitution - coding silent
c.375C>T; p.I125I; 3:120409619-120409619	skin	malignant_melanoma	Substitution - coding silent
c.75G>A; p.R25R; 3:120416016-120416016	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.118C>T; p.R40W; 3:120415973-120415973	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.33G>C; p.A11A; 3:120450714-120450714	skin	malignant_melanoma	Substitution - coding silent
c.202A>C; p.S68R; 3:120411950-120411950	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.367C>T; p.R123C; 3:120409627-120409627	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.585A>T; p.G195G; 3:120403351-120403351	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.578T>G; p.L193R; 3:120404856-120404856	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.485G>T; p.R162L; 3:120404949-120404949	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.285T>C; p.D95D; 3:120411867-120411867	breast	carcinoma	Substitution - coding silent
c.537C>T; p.I179I; 3:120404897-120404897	skin	malignant_melanoma	Substitution - coding silent
c.832C>A; p.Q278K; 3:120399933-120399933	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.260G>C; p.G87A; 3:120411892-120411892	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.260G>C; p.G87A; 3:120411892-120411892	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.83C>T; p.S28F; 3:120416008-120416008	skin	malignant_melanoma	Substitution - Missense
c.914C>T; p.T305I; 3:120396965-120396965	skin; trunk	malignant_melanoma	Substitution - Missense
c.365G>A; p.R122Q; 3:120409629-120409629	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.365G>A; p.R122Q; 3:120409629-120409629	breast	carcinoma	Substitution - Missense

Annotation category 5

Basic annotation

Literature evidence

Expression

Somatic mutation

Network

ceRNA

Gene information

COSMIC somatic mutation