lung cancer gene and literature database Home

Annotation category 5

Basic annotation
Ontology and pathways
Literature evidence
Curated literatures
Expression
Gene expression chart
Somatic mutation
COSMIC and TCGA mutations
Network
Gene interaction
ceRNA
Gene-related ceRNA

Gene information

Gene ID	11082
Symbol	ESM1
Synonymous	endocan
Full name	endothelial cell-specific molecule 1
Gene description	ESM-1
Cytoband	5q11.2
Gene type	protein-coding
Synonymous	MIM:601521; HGNC:HGNC:3466; Ensembl:ENSG00000164283; HPRD:03310; Vega:OTTHUMG00000097010

COSMIC somatic mutation

Mutation (CDS; AA; Chr)	Site	Histology	Mutation Type
c.328G>T; p.D110Y; 5:54982120-54982120	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.292A>G; p.I98V; 5:54985226-54985226	skin	malignant_melanoma	Substitution - Missense
c.379G>A; p.G127R; 5:54982069-54982069	skin	malignant_melanoma	Substitution - Missense
c.322G>T; p.G108W; 5:54982126-54982126	adrenal_gland; adrenal_gland	adrenal_cortical_carcinoma; functioning	Substitution - Missense
c.171C>T; p.C57C; 5:54985347-54985347	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.171C>T; p.C57C; 5:54985347-54985347	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - coding silent
c.313G>A; p.G105S; 5:54982135-54982135	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.209C>T; p.S70L; 5:54985309-54985309	skin	malignant_melanoma	Substitution - Missense
c.181C>T; p.R61W; 5:54985337-54985337	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.277G>C; p.G93R; 5:54985241-54985241	oesophagus; lower_third	carcinoma; adenocarcinoma	Substitution - Missense
c.181C>T; p.R61W; 5:54985337-54985337	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.163C>T; p.R55*; 5:54985355-54985355	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Nonsense
c.421A>C; p.K141Q; 5:54982027-54982027	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.380G>A; p.G127E; 5:54982068-54982068	skin	malignant_melanoma	Substitution - Missense
c.432C>T; p.N144N; 5:54982016-54982016	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.34G>A; p.V12M; 5:54985484-54985484	liver	carcinoma	Substitution - Missense
c.439G>C; p.V147L; 5:54982009-54982009	prostate	carcinoma; adenocarcinoma	Substitution - Missense
c.525C>T; p.P175P; 5:54979362-54979362	oesophagus	carcinoma; adenocarcinoma	Substitution - coding silent
c.485T>C; p.V162A; 5:54979402-54979402	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.337G>T; p.E113*; 5:54982111-54982111	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Nonsense
c.147C>T; p.D49D; 5:54985371-54985371	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.359G>A; p.G120D; 5:54982089-54982089	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.523C>T; p.P175S; 5:54979364-54979364	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.350G>A; p.C117Y; 5:54982098-54982098	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.26C>T; p.T9M; 5:54985492-54985492	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.307C>T; p.P103S; 5:54982141-54982141	skin	malignant_melanoma	Substitution - Missense
c.554G>T; p.*185L; 5:54979333-54979333	breast	carcinoma; ductal_carcinoma	Nonstop extension
c.490G>A; p.E164K; 5:54979397-54979397	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.182G>A; p.R61Q; 5:54985336-54985336	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.324G>A; p.G108G; 5:54982124-54982124	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.534G>A; p.R178R; 5:54979353-54979353	skin	malignant_melanoma	Substitution - coding silent
c.117C>A; p.S39R; 5:54985401-54985401	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.534G>A; p.R178R; 5:54979353-54979353	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.273T>C; p.P91P; 5:54985245-54985245	skin	malignant_melanoma	Substitution - coding silent
c.60G>A; p.W20*; 5:54985458-54985458	oesophagus; middle_third	carcinoma; squamous_cell_carcinoma	Substitution - Nonsense
c.21G>C; p.L7L; 5:54985497-54985497	prostate	carcinoma; adenocarcinoma	Substitution - coding silent
c.124C>T; p.R42C; 5:54985394-54985394	stomach	carcinoma; intestinal_adenocarcinoma	Substitution - Missense
c.449C>T; p.T150M; 5:54981999-54981999	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.449C>T; p.T150M; 5:54981999-54981999	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.280G>A; p.E94K; 5:54985238-54985238	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.360C>A; p.G120G; 5:54982088-54982088	oesophagus; lower_third	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.12C>T; p.V4V; 5:54985506-54985506	skin	malignant_melanoma	Substitution - coding silent
c.33C>T; p.L11L; 5:54985485-54985485	skin	malignant_melanoma	Substitution - coding silent
c.516C>T; p.A172A; 5:54979371-54979371	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.526G>A; p.V176I; 5:54979361-54979361	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.397C>T; p.P133S; 5:54982051-54982051	skin	malignant_melanoma	Substitution - Missense
c.475G>A; p.G159S; 5:54979412-54979412	oesophagus; lower_third	carcinoma; adenocarcinoma	Substitution - Missense
c.274T>C; p.F92L; 5:54985244-54985244	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.272C>T; p.P91L; 5:54985246-54985246	skin	malignant_melanoma	Substitution - Missense
c.439G>A; p.V147I; 5:54982009-54982009	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.252G>A; p.Q84Q; 5:54985266-54985266	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - coding silent
c.490G>T; p.E164*; 5:54979397-54979397	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Nonsense
c.458A>T; p.D153V; 5:54979429-54979429	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.378G>T; p.T126T; 5:54982070-54982070	skin	malignant_melanoma	Substitution - coding silent
c.493G>A; p.E165K; 5:54979394-54979394	skin	malignant_melanoma	Substitution - Missense
c.46C>T; p.L16L; 5:54985472-54985472	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.76G>A; p.V26M; 5:54985442-54985442	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.339G>A; p.E113E; 5:54982109-54982109	urinary_tract; bladder	carcinoma	Substitution - coding silent
c.339G>A; p.E113E; 5:54982109-54982109	urinary_tract; bladder	carcinoma; transitional_cell_carcinoma	Substitution - coding silent
c.371G>A; p.R124K; 5:54982077-54982077	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.245G>C; p.R82T; 5:54985273-54985273	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.354G>A; p.Q118Q; 5:54982094-54982094	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.217G>A; p.D73N; 5:54985301-54985301	skin	malignant_melanoma	Substitution - Missense
c.31C>T; p.L11F; 5:54985487-54985487	skin	malignant_melanoma	Substitution - Missense
c.179G>T; p.G60V; 5:54985339-54985339	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.464C>A; p.A155E; 5:54979423-54979423	stomach	carcinoma; adenocarcinoma	Substitution - Missense

Annotation category 5

Basic annotation

Literature evidence

Expression

Somatic mutation

Network

ceRNA

Gene information

COSMIC somatic mutation