lung cancer gene and literature database Home

Annotation category 5

Basic annotation
Ontology and pathways
Literature evidence
Curated literatures
Expression
Gene expression chart
Somatic mutation
COSMIC and TCGA mutations
Network
Gene interaction
ceRNA
Gene-related ceRNA

Gene information

Gene ID	11074
Symbol	TRIM31
Synonymous	C6orf13\|HCG1\|HCGI\|RNF
Full name	tripartite motif containing 31
Gene description	E3 ubiquitin-protein ligase TRIM31\|ring finger protein\|tripartite motif-containing 31 gamma\|tripartite motif-containing protein 31
Cytoband	6p21.3
Gene type	protein-coding
Synonymous	MIM:609316; HGNC:HGNC:16289; Ensembl:ENSG00000204616; HPRD:10281; Vega:OTTHUMG00000031064

COSMIC somatic mutation

Mutation (CDS; AA; Chr)	Site	Histology	Mutation Type
c.12G>A; p.G4G; 6:30112794-30112794	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.869_870insG; p.F293fs*8; 6:30108066-30108067	lung	carcinoma; adenocarcinoma	Insertion - Frameshift
c.862G>A; p.G288R; 6:30108074-30108074	skin	malignant_melanoma	Substitution - Missense
c.1190A>G; p.D397G; 6:30103624-30103624	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.50C>T; p.P17L; 6:30112756-30112756	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.642G>A; p.G214G; 6:30110550-30110550	skin	malignant_melanoma	Substitution - coding silent
c.642G>A; p.G214G; 6:30110550-30110550	skin	malignant_melanoma	Substitution - coding silent
c.564G>A; p.L188L; 6:30110628-30110628	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.642G>A; p.G214G; 6:30110550-30110550	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - coding silent
c.487G>A; p.G163S; 6:30111674-30111674	liver	carcinoma	Substitution - Missense
c.487G>A; p.G163S; 6:30111674-30111674	liver	carcinoma	Substitution - Missense
c.655G>A; p.A219T; 6:30110537-30110537	prostate	carcinoma; adenocarcinoma	Substitution - Missense
c.439C>T; p.Q147*; 6:30111722-30111722	skin	malignant_melanoma	Substitution - Nonsense
c.855C>T; p.S285S; 6:30108081-30108081	skin	malignant_melanoma	Substitution - coding silent
c.756C>T; p.V252V; 6:30109037-30109037	skin	malignant_melanoma	Substitution - coding silent
c.616C>T; p.L206L; 6:30110576-30110576	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1238C>T; p.T413I; 6:30103576-30103576	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.726A>G; p.P242P; 6:30110466-30110466	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.375C>T; p.S125S; 6:30112431-30112431	skin	malignant_melanoma	Substitution - coding silent
c.269G>A; p.R90K; 6:30112537-30112537	skin	malignant_melanoma	Substitution - Missense
c.31C>A; p.Q11K; 6:30112775-30112775	autonomic_ganglia	neuroblastoma	Substitution - Missense
c.960G>A; p.W320*; 6:30104166-30104166	skin	malignant_melanoma	Substitution - Nonsense
c.270G>A; p.R90R; 6:30112536-30112536	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.853T>G; p.S285A; 6:30108083-30108083	liver	carcinoma; hepatocellular_carcinoma	Substitution - Missense
c.853T>G; p.S285A; 6:30108083-30108083	liver	carcinoma	Substitution - Missense
c.1011G>A; p.G337G; 6:30104115-30104115	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.301A>C; p.M101L; 6:30112505-30112505	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.31delC; p.Q11fs*4; 6:30112775-30112775	lung	carcinoma; small_cell_carcinoma	Deletion - Frameshift
c.742G>A; p.E248K; 6:30110450-30110450	skin	malignant_melanoma	Substitution - Missense
c.178G>A; p.V60I; 6:30112628-30112628	prostate	carcinoma; adenocarcinoma	Substitution - Missense
c.1141G>A; p.D381N; 6:30103673-30103673	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.781C>A; p.Q261K; 6:30108155-30108155	skin	malignant_melanoma	Substitution - Missense
c.800C>T; p.P267L; 6:30108136-30108136	skin	malignant_melanoma	Substitution - Missense
c.352C>T; p.R118C; 6:30112454-30112454	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.610T>G; p.Y204D; 6:30110582-30110582	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.307C>T; p.H103Y; 6:30112499-30112499	oesophagus; middle_third	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1093T>G; p.S365A; 6:30103721-30103721	prostate	carcinoma; adenocarcinoma	Substitution - Missense
c.1236G>A; p.L412L; 6:30103578-30103578	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - coding silent
c.460_462delAAG; p.K154delK; 6:30111699-30111701	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - In frame
c.1026C>T; p.G342G; 6:30103788-30103788	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1204G>A; p.E402K; 6:30103610-30103610	salivary_gland; parotid	carcinoma; adenoid_cystic_carcinoma	Substitution - Missense
c.1118C>T; p.P373L; 6:30103696-30103696	central_nervous_system; brain	primitive_neuroectodermal_tumour-medulloblastoma	Substitution - Missense
c.637G>A; p.A213T; 6:30110555-30110555	skin; trunk	malignant_melanoma	Substitution - Missense
c.729C>T; p.P243P; 6:30110463-30110463	lung	carcinoma	Substitution - coding silent
c.193A>C; p.I65L; 6:30112613-30112613	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.740T>G; p.L247R; 6:30110452-30110452	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.13C>A; p.Q5K; 6:30112793-30112793	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.193A>G; p.I65V; 6:30112613-30112613	urinary_tract; bladder	carcinoma	Substitution - Missense
c.723G>A; p.M241I; 6:30110469-30110469	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1100C>A; p.A367D; 6:30103714-30103714	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.98A>C; p.H33P; 6:30112708-30112708	skin	malignant_melanoma	Substitution - Missense
c.300G>A; p.E100E; 6:30112506-30112506	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.423G>A; p.Q141Q; 6:30111738-30111738	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.574C>T; p.L192L; 6:30110618-30110618	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1042G>A; p.G348R; 6:30103772-30103772	urinary_tract; bladder	carcinoma	Substitution - Missense
c.539G>T; p.R180M; 6:30110653-30110653	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.454A>C; p.K152Q; 6:30111707-30111707	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.364G>A; p.D122N; 6:30112442-30112442	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.849T>C; p.H283H; 6:30108087-30108087	prostate	carcinoma; adenocarcinoma	Substitution - coding silent
c.638C>T; p.A213V; 6:30110554-30110554	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.435G>A; p.Q145Q; 6:30111726-30111726	bone; femur	chondrosarcoma	Substitution - coding silent
c.810G>A; p.L270L; 6:30108126-30108126	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.88G>A; p.D30N; 6:30112718-30112718	urinary_tract; bladder	carcinoma	Substitution - Missense
c.305T>A; p.F102Y; 6:30112501-30112501	skin	malignant_melanoma	Substitution - Missense
c.162C>T; p.P54P; 6:30112644-30112644	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.992A>T; p.N331I; 6:30104134-30104134	stomach	carcinoma; intestinal_adenocarcinoma	Substitution - Missense
c.598C>A; p.L200I; 6:30110594-30110594	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.177C>T; p.S59S; 6:30112629-30112629	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.728C>T; p.P243L; 6:30110464-30110464	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.728C>T; p.P243L; 6:30110464-30110464	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.1152T>C; p.S384S; 6:30103662-30103662	ovary	carcinoma; serous_carcinoma	Substitution - coding silent
c.438C>T; p.I146I; 6:30111723-30111723	skin	malignant_melanoma	Substitution - coding silent
c.1062T>A; p.S354S; 6:30103752-30103752	skin	malignant_melanoma	Substitution - coding silent
c.903G>A; p.R301R; 6:30105223-30105223	skin; head_neck	malignant_melanoma; superficial_spreading	Substitution - coding silent
c.903G>A; p.R301R; 6:30105223-30105223	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.918C>G; p.N306K; 6:30105208-30105208	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.791A>G; p.N264S; 6:30108145-30108145	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.876delA; p.K292fs*21; 6:30108060-30108060	large_intestine	carcinoma; adenocarcinoma	Deletion - Frameshift
c.1261G>A; p.E421K; 6:30103553-30103553	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.520G>A; p.V174I; 6:30110672-30110672	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.520G>A; p.V174I; 6:30110672-30110672	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.30G>A; p.L10L; 6:30112776-30112776	lung	carcinoma; small_cell_carcinoma	Substitution - coding silent

Annotation category 5

Basic annotation

Literature evidence

Expression

Somatic mutation

Network

ceRNA

Gene information

COSMIC somatic mutation