lung cancer gene and literature database Home

Annotation category 5

Basic annotation
Ontology and pathways
Literature evidence
Curated literatures
Expression
Gene expression chart
Somatic mutation
COSMIC and TCGA mutations
Network
Gene interaction
ceRNA
Gene-related ceRNA

Gene information

Gene ID	11009
Symbol	IL24
Synonymous	C49A\|FISP\|IL10B\|MDA7\|MOB5\|ST16
Full name	interleukin 24
Gene description	IL-4-induced secreted protein\|interleukin-24\|melanocyte-associated Mda-7\|melanoma differentiation-associated gene 7 protein\|suppression of tumorigenicity 16 (melanoma differentiation)
Cytoband	1q32
Gene type	protein-coding
Synonymous	MIM:604136; HGNC:HGNC:11346; Ensembl:ENSG00000162892; HPRD:04995; Vega:OTTHUMG00000036459

COSMIC somatic mutation

Mutation (CDS; AA; Chr)	Site	Histology	Mutation Type
c.69G>A; p.A23A; 1:206899344-206899344	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - coding silent
c.522G>A; p.R174R; 1:206902057-206902057	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.429C>G; p.N143K; 1:206901619-206901619	soft_tissue; striated_muscle	rhabdomyosarcoma	Substitution - Missense
c.351G>A; p.L117L; 1:206901541-206901541	skin	malignant_melanoma	Substitution - coding silent
c.125T>A; p.L42H; 1:206899400-206899400	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.147C>T; p.A49A; 1:206899422-206899422	prostate	carcinoma	Substitution - coding silent
c.147C>T; p.A49A; 1:206899422-206899422	liver	carcinoma	Substitution - coding silent
c.147C>T; p.A49A; 1:206899422-206899422	liver	carcinoma	Substitution - coding silent
c.86A>G; p.Q29R; 1:206899361-206899361	urinary_tract; bladder	carcinoma	Substitution - Missense
c.597G>A; p.W199*; 1:206903035-206903035	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Nonsense
c.578T>C; p.V193A; 1:206903016-206903016	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.578T>C; p.V193A; 1:206903016-206903016	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.47C>T; p.P16L; 1:206899322-206899322	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.172C>T; p.P58S; 1:206899447-206899447	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.297C>T; p.N99N; 1:206900351-206900351	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.40G>T; p.A14S; 1:206897872-206897872	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.298G>A; p.V100I; 1:206900352-206900352	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.278A>T; p.Q93L; 1:206900332-206900332	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.565G>A; p.A189T; 1:206903003-206903003	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.146C>T; p.A49V; 1:206899421-206899421	kidney	other; neoplasm	Substitution - Missense
c.87G>T; p.Q29H; 1:206899362-206899362	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.454C>A; p.Q152K; 1:206901644-206901644	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.397A>G; p.T133A; 1:206901587-206901587	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.397A>G; p.T133A; 1:206901587-206901587	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.428A>C; p.N143T; 1:206901618-206901618	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.439A>G; p.I147V; 1:206901629-206901629	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.460A>T; p.S154C; 1:206901650-206901650	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.163C>T; p.H55Y; 1:206899438-206899438	lung	carcinoma; small_cell_carcinoma	Substitution - Missense
c.211G>A; p.E71K; 1:206899486-206899486	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.211G>A; p.E71K; 1:206899486-206899486	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.149A>G; p.Q50R; 1:206899424-206899424	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.568C>T; p.L190F; 1:206903006-206903006	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.27C>T; p.S9S; 1:206897859-206897859	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.345C>G; p.F115L; 1:206901535-206901535	breast	carcinoma	Substitution - Missense
c.442G>A; p.V148M; 1:206901632-206901632	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.249G>A; p.Q83Q; 1:206900303-206900303	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.508T>A; p.F170I; 1:206902043-206902043	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.363C>G; p.F121L; 1:206901553-206901553	breast	carcinoma	Substitution - Missense
c.564A>C; p.K188N; 1:206903002-206903002	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.388G>A; p.E130K; 1:206901578-206901578	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.416C>A; p.T139N; 1:206901606-206901606	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.334C>T; p.L112L; 1:206901524-206901524	liver	carcinoma	Substitution - coding silent
c.334C>T; p.L112L; 1:206901524-206901524	liver	carcinoma	Substitution - coding silent
c.133C>A; p.Q45K; 1:206899408-206899408	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense

Annotation category 5

Basic annotation

Literature evidence

Expression

Somatic mutation

Network

ceRNA

Gene information

COSMIC somatic mutation