Cancer metastasis database

Annotation category 5

Gene information

Gene ID 10935
Symbol

PRDX3

Synonymous

AOP-1|AOP1|HBC189|MER5|PRO1748|SP-22|prx-III

Full name

peroxiredoxin 3

Gene description

antioxidant protein 1|peroxiredoxin III|peroxiredoxin-3|protein MER5 homolog|thioredoxin-dependent peroxide reductase, mitochondrial

Cytoband

10q25-q26

Gene type

protein-coding

Synonymous

MIM:604769; HGNC:HGNC:9354; Ensembl:ENSG00000165672; HPRD:05305; Vega:OTTHUMG00000019146

COSMIC somatic mutation

Mutation (CDS; AA; Chr)

Site

Histology

Mutation Type

c.717G>A; p.T239T; 10:119169177-119169177

 urinary_tract; bladdercarcinomaSubstitution - coding silent

c.604G>A; p.D202N; 10:119169290-119169290

 breastcarcinomaSubstitution - Missense

c.640C>T; p.R214C; 10:119169254-119169254

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.92_93GG>TT; p.R31I; 10:119177097-119177098

 lung; right_upper_lobecarcinoma; adenocarcinomaSubstitution - Missense

c.589C>T; p.H197Y; 10:119169305-119169305

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.68_69insG; p.I24fs*50; 10:119177121-119177122

 lungcarcinoma; small_cell_carcinomaInsertion - Frameshift

c.476C>T; p.A159V; 10:119172457-119172457

 lung; right_upper_lobecarcinoma; adenocarcinomaSubstitution - Missense

c.136T>G; p.S46A; 10:119177054-119177054

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.754C>T; p.Q252*; 10:119168497-119168497

 oesophagus; lower_thirdcarcinoma; adenocarcinomaSubstitution - Nonsense

c.625G>A; p.V209M; 10:119169269-119169269

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.625G>A; p.V209M; 10:119169269-119169269

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.557T>A; p.L186H; 10:119169337-119169337

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.283T>G; p.L95V; 10:119174479-119174479

 stomachcarcinoma; intestinal_adenocarcinomaSubstitution - Missense

c.390C>T; p.V130V; 10:119173794-119173794

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.516C>T; p.Y172Y; 10:119172417-119172417

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.628G>A; p.E210K; 10:119169266-119169266

 urinary_tract; bladdercarcinomaSubstitution - Missense

c.628G>A; p.E210K; 10:119169266-119169266

 urinary_tract; bladdercarcinoma; transitional_cell_carcinomaSubstitution - Missense

c.407C>T; p.S136F; 10:119173777-119173777

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.361G>A; p.E121K; 10:119173823-119173823

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.361G>A; p.E121K; 10:119173823-119173823

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.285G>A; p.L95L; 10:119174477-119174477

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.212A>G; p.Y71C; 10:119174550-119174550

 pancreascarcinomaSubstitution - Missense

c.512A>G; p.D171G; 10:119172421-119172421

 lungcarcinoid-endocrine_tumour; atypicalSubstitution - Missense

c.301C>T; p.P101S; 10:119174461-119174461

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.624C>T; p.S208S; 10:119169270-119169270

 boneEwings_sarcoma-peripheral_primitive_neuroectodermal_tumourSubstitution - coding silent

c.207A>T; p.A69A; 10:119174555-119174555

 pancreascarcinoma; ductal_carcinomaSubstitution - coding silent

c.207A>T; p.A69A; 10:119174555-119174555

 pancreascarcinomaSubstitution - coding silent

c.227C>T; p.A76V; 10:119174535-119174535

 skinmalignant_melanomaSubstitution - Missense

c.322T>C; p.C108R; 10:119173862-119173862

 livercarcinomaSubstitution - Missense

c.120G>A; p.L40L; 10:119177070-119177070

 breastcarcinomaSubstitution - coding silent

c.8C>T; p.A3V; 10:119178783-119178783

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.98C>G; p.A33G; 10:119177092-119177092

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - Missense