lung cancer gene and literature database Home

Annotation category 5

Basic annotation
Ontology and pathways
Literature evidence
Curated literatures
Expression
Gene expression chart
Somatic mutation
COSMIC and TCGA mutations
Network
Gene interaction
ceRNA
Gene-related ceRNA

Gene information

Gene ID	10928
Symbol	RALBP1
Synonymous	RIP1\|RLIP1\|RLIP76
Full name	ralA binding protein 1
Gene description	76 kDa Ral-interacting protein\|DNP-SG ATPase\|dinitrophenyl S-glutathione ATPase\|ral-interacting protein 1\|ralA-binding protein 1
Cytoband	18p11.3
Gene type	protein-coding
Synonymous	MIM:605801; HGNC:HGNC:9841; Ensembl:ENSG00000017797; HPRD:09013; Vega:OTTHUMG00000131596

COSMIC somatic mutation

Mutation (CDS; AA; Chr)	Site	Histology	Mutation Type
c.211delA; p.K74fs*30; 18:9513256-9513256	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.1752C>G; p.I584M; 18:9535721-9535721	kidney	carcinoma; papillary_renal_cell_carcinoma	Substitution - Missense
c.670G>A; p.G224S; 18:9517270-9517270	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1191C>T; p.G397G; 18:9524731-9524731	autonomic_ganglia	neuroblastoma	Substitution - coding silent
c.317C>T; p.S106F; 18:9516917-9516917	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.632C>T; p.A211V; 18:9517232-9517232	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.642T>C; p.R214R; 18:9517242-9517242	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.202C>G; p.H68D; 18:9513247-9513247	breast	carcinoma	Substitution - Missense
c.1166C>G; p.P389R; 18:9524706-9524706	kidney	carcinoma; papillary_renal_cell_carcinoma	Substitution - Missense
c.1278A>C; p.E426D; 18:9525782-9525782	breast	carcinoma	Substitution - Missense
c.1879G>C; p.E627Q; 18:9535848-9535848	urinary_tract; bladder	carcinoma	Substitution - Missense
c.1546C>T; p.R516C; 18:9533425-9533425	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1763G>A; p.R588H; 18:9535732-9535732	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1142G>A; p.R381Q; 18:9524682-9524682	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1580G>A; p.R527H; 18:9533705-9533705	oesophagus; lower_third	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1064G>A; p.R355Q; 18:9524604-9524604	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1935G>A; p.S645S; 18:9535904-9535904	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.1064G>A; p.R355Q; 18:9524604-9524604	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1302A>C; p.R434S; 18:9525806-9525806	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1528G>C; p.E510Q; 18:9533407-9533407	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1279G>T; p.E427*; 18:9525783-9525783	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Nonsense
c.1822G>A; p.D608N; 18:9535791-9535791	central_nervous_system; brain	glioma	Substitution - Missense
c.364G>T; p.E122*; 18:9516964-9516964	lung	carcinoma; adenocarcinoma	Substitution - Nonsense
c.1147T>G; p.S383A; 18:9524687-9524687	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.828G>A; p.E276E; 18:9522284-9522284	skin	malignant_melanoma	Substitution - coding silent
c.1922C>T; p.P641L; 18:9535891-9535891	skin	malignant_melanoma	Substitution - Missense
c.814C>T; p.R272*; 18:9522270-9522270	prostate	carcinoma; adenocarcinoma	Substitution - Nonsense
c.1623G>T; p.E541D; 18:9533748-9533748	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.498G>T; p.K166N; 18:9517098-9517098	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.801G>A; p.L267L; 18:9522257-9522257	urinary_tract; bladder	carcinoma	Substitution - coding silent
c.828G>T; p.E276D; 18:9522284-9522284	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1455+1G>C; p.?; 18:9530942-9530942	autonomic_ganglia	neuroblastoma	Unknown
c.1620C>A; p.S540S; 18:9533745-9533745	skin	malignant_melanoma	Substitution - coding silent
c.138G>A; p.E46E; 18:9513183-9513183	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.1557T>C; p.A519A; 18:9533436-9533436	bone; tibia	Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	Substitution - coding silent
c.1730T>G; p.I577S; 18:9535699-9535699	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1255G>A; p.G419R; 18:9525759-9525759	skin	malignant_melanoma	Substitution - Missense
c.1254T>G; p.G418G; 18:9525758-9525758	breast	carcinoma	Substitution - coding silent
c.1059C>T; p.S353S; 18:9524599-9524599	breast	carcinoma	Substitution - coding silent
c.393C>A; p.P131P; 18:9516993-9516993	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; chronic_lymphocytic_leukaemia-small_lymphocytic_lymphoma	Substitution - coding silent
c.1082T>A; p.F361Y; 18:9524622-9524622	skin	malignant_melanoma	Substitution - Missense
c.1086A>G; p.T362T; 18:9524626-9524626	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.1374G>A; p.E458E; 18:9530860-9530860	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.1934C>T; p.S645L; 18:9535903-9535903	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; mantle_cell_lymphoma	Substitution - Missense
c.1934C>T; p.S645L; 18:9535903-9535903	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.295A>G; p.S99G; 18:9516895-9516895	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.295A>G; p.S99G; 18:9516895-9516895	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.1157_1158CC>TT; p.A386V; 18:9524697-9524698	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1590C>T; p.H530H; 18:9533715-9533715	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.1590C>T; p.H530H; 18:9533715-9533715	skin	malignant_melanoma	Substitution - coding silent
c.805C>T; p.Q269*; 18:9522261-9522261	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Nonsense
c.41A>G; p.E14G; 18:9513086-9513086	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.128G>A; p.R43H; 18:9513173-9513173	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1594C>T; p.R532*; 18:9533719-9533719	large_intestine	carcinoma; adenocarcinoma	Substitution - Nonsense
c.540G>T; p.Q180H; 18:9517140-9517140	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1594C>T; p.R532*; 18:9533719-9533719	large_intestine	carcinoma; adenocarcinoma	Substitution - Nonsense
c.749A>G; p.E250G; 18:9522205-9522205	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.283G>A; p.D95N; 18:9516883-9516883	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.1375A>G; p.I459V; 18:9530861-9530861	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.1949G>A; p.R650K; 18:9535918-9535918	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.657C>T; p.Y219Y; 18:9517257-9517257	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.1528G>A; p.E510K; 18:9533407-9533407	pancreas	carcinoma	Substitution - Missense
c.1873G>A; p.V625I; 18:9535842-9535842	bone; femur	Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	Substitution - Missense
c.1515G>A; p.R505R; 18:9533394-9533394	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.1626C>T; p.S542S; 18:9533751-9533751	breast	carcinoma	Substitution - coding silent
c.162_163CC>TT; p.H55Y; 18:9513207-9513208	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.387G>A; p.E129E; 18:9516987-9516987	bone	Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	Substitution - coding silent
c.124T>C; p.Y42H; 18:9513169-9513169	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.1316T>C; p.L439P; 18:9525820-9525820	breast	carcinoma	Substitution - Missense
c.686G>A; p.G229D; 18:9517286-9517286	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1959G>A; p.T653T; 18:9535928-9535928	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.601A>G; p.T201A; 18:9517201-9517201	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.321G>C; p.K107N; 18:9516921-9516921	breast	carcinoma	Substitution - Missense
c.1187C>T; p.A396V; 18:9524727-9524727	autonomic_ganglia	neuroblastoma	Substitution - Missense
c.1815G>A; p.A605A; 18:9535784-9535784	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1182C>T; p.T394T; 18:9524722-9524722	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1162A>C; p.M388L; 18:9524702-9524702	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.1842C>T; p.R614R; 18:9535811-9535811	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.703G>T; p.G235*; 18:9517303-9517303	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Nonsense
c.1840C>T; p.R614C; 18:9535809-9535809	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1328T>G; p.L443R; 18:9525832-9525832	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.247G>A; p.E83K; 18:9516847-9516847	upper_aerodigestive_tract; mouth	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.913C>T; p.R305C; 18:9522369-9522369	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.472G>C; p.D158H; 18:9517072-9517072	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.925G>T; p.E309*; 18:9522381-9522381	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Nonsense
c.155A>G; p.D52G; 18:9513200-9513200	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1240C>T; p.R414*; 18:9525744-9525744	skin	malignant_melanoma	Substitution - Nonsense
c.1488C>T; p.L496L; 18:9533367-9533367	skin	malignant_melanoma	Substitution - coding silent
c.1518G>C; p.Q506H; 18:9533397-9533397	pancreas	carcinoma	Substitution - Missense
c.1938C>T; p.P646P; 18:9535907-9535907	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1073A>G; p.Y358C; 18:9524613-9524613	urinary_tract; bladder	carcinoma; transitional_cell_carcinoma	Substitution - Missense
c.392C>T; p.P131L; 18:9516992-9516992	skin	malignant_melanoma	Substitution - Missense
c.1073A>G; p.Y358C; 18:9524613-9524613	urinary_tract; bladder	carcinoma	Substitution - Missense
c.1063C>T; p.R355*; 18:9524603-9524603	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Nonsense

Annotation category 5

Basic annotation

Literature evidence

Expression

Somatic mutation

Network

ceRNA

Gene information

COSMIC somatic mutation